메뉴 건너뛰기




Volumn 340, Issue 1, 2010, Pages 209-228

Plasticity of immunological synapses

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; REGULATOR PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 77950876065     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-03858-7_11     Document Type: Review
Times cited : (10)

References (89)
  • 1
    • 33846246384 scopus 로고    scopus 로고
    • Force as a Facilitator of Integrin Conformational Changes during Leukocyte Arrest on Blood Vessels and Antigen-Presenting Cells
    • DOI 10.1016/j.immuni.2007.01.002, PII S1074761307001021
    • Alon R, Dustin ML (2007) Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity 26:17-27 (Pubitemid 46109349)
    • (2007) Immunity , vol.26 , Issue.1 , pp. 17-27
    • Alon, R.1    Dustin, M.L.2
  • 2
    • 0347915637 scopus 로고    scopus 로고
    • Fyn and PTP-PEST-mediated Regulation of Wiskott-Aldrich Syndrome Protein (WASp) Tyrosine Phosphorylation Is Required for Coupling T Cell Antigen Receptor Engagement to WASp Effector Function and T Cell Activation
    • DOI 10.1084/jem.20030976
    • Badour K, Zhang J, Shi F, Leng Y, Collins M, Siminovitch KA (2004) Fyn and PTP-PESTmediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation. J Exp Med 199:99-112 (Pubitemid 38076482)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.1 , pp. 99-111
    • Badour, K.1    Zhang, J.2    Shi, F.3    Leng, Y.4    Collins, M.5    Siminovitch, K.A.6
  • 3
    • 33845455093 scopus 로고    scopus 로고
    • Stromal Cell Networks Regulate Lymphocyte Entry, Migration, and Territoriality in Lymph Nodes
    • DOI 10.1016/j.immuni.2006.10.011, PII S1074761306004833
    • Bajenoff M, Egen JG, Koo LY, Laugier JP, Brau F, Glaichenhaus N, Germain RN (2006) Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25:989-1001 (Pubitemid 44914055)
    • (2006) Immunity , vol.25 , Issue.6 , pp. 989-1001
    • Bajenoff, M.1    Egen, J.G.2    Koo, L.Y.3    Laugier, J.4    Brau, F.5    Glaichenhaus, N.6    Germain, R.N.7
  • 5
    • 33846626054 scopus 로고    scopus 로고
    • Regulation of T-cell activation by the cytoskeleton
    • Billadeau DD, Nolz JC, Gomez TS (2007) Regulation of T-cell activation by the cytoskeleton. Nat Rev Immunol 7:131-143
    • (2007) Nat Rev Immunol , vol.7 , pp. 131-143
    • Billadeau, D.D.1    Nolz, J.C.2    Gomez, T.S.3
  • 6
    • 0037501371 scopus 로고    scopus 로고
    • + T cell priming by dendritic cells in intact lymph nodes
    • DOI 10.1038/ni928
    • Bousso P, Robey E (2003) Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nat Immunol 4:579-585 (Pubitemid 36701342)
    • (2003) Nature Immunology , vol.4 , Issue.6 , pp. 579-585
    • Bousso, P.1    Robey, E.2
  • 8
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
    • DOI 10.1084/jem.20051182
    • Campi G, Varma R, Dustin ML (2005) Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med 202:1031-1036 (Pubitemid 41540032)
    • (2005) Journal of Cell Biology , vol.171 , Issue.2 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 9
    • 3242762840 scopus 로고    scopus 로고
    • Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production
    • Cannon J, Burkhardt J (2004) Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production. J Immunol 173:1658-1662 (Pubitemid 38971596)
    • (2004) Journal of Immunology , vol.173 , Issue.3 , pp. 1658-1662
    • Cannon, J.L.1    Burkhardt, J.K.2
  • 11
    • 33645866471 scopus 로고    scopus 로고
    • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
    • Castellino F, Huang AY, Altan-Bonnet G, Stoll S, Scheinecker C, Germain RN (2006) Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature 440:890-895
    • (2006) Nature , vol.440 , pp. 890-895
    • Castellino, F.1    Huang, A.Y.2    Altan-Bonnet, G.3    Stoll, S.4    Scheinecker, C.5    Germain, R.N.6
  • 12
    • 27744502556 scopus 로고    scopus 로고
    • CD4 T cells integrate signals delivered during successive DC encounters in vivo
    • DOI 10.1084/jem.20051018
    • Celli S, Garcia Z, Bousso P (2005) CD4 T cells integrate signals delivered during successive DC encounters in vivo. J Exp Med 202:1271-1278 (Pubitemid 41586957)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.9 , pp. 1271-1278
    • Celli, S.1    Garcia, Z.2    Bousso, P.3
  • 13
    • 35348978611 scopus 로고    scopus 로고
    • + T Cell Activation
    • DOI 10.1016/j.immuni.2007.08.018, PII S1074761307004517
    • Celli S, Lemaitre F, Bousso P (2007) Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation. Immunity 27:625-634 (Pubitemid 47615508)
    • (2007) Immunity , vol.27 , Issue.4 , pp. 625-634
    • Celli, S.1    Lemaitre, F.2    Bousso, P.3
  • 15
    • 51349131307 scopus 로고    scopus 로고
    • The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
    • Cemerski S, Das J, Giurisato E, Markiewicz MA, Allen PM, Chakraborty AK, Shaw AS (2008) The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity 29:414-422
    • (2008) Immunity , vol.29 , pp. 414-422
    • Cemerski, S.1    Das, J.2    Giurisato, E.3    Markiewicz, M.A.4    Allen, P.M.5    Chakraborty, A.K.6    Shaw, A.S.7
  • 17
    • 0035652354 scopus 로고    scopus 로고
    • Exclusion of CD43 from the immunological synapce is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor Moesin
    • DOI 10.1016/S1074-7613(01)00231-X
    • Delon J, Kaibuchi K, Germain RN (2001) Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 15:691-701 (Pubitemid 34008498)
    • (2001) Immunity , vol.15 , Issue.5 , pp. 691-701
    • Delon, J.1    Kaibuchi, K.2    Germain, R.N.3
  • 19
    • 0036669692 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation
    • DOI 10.1016/S1074-7613(02)00360-6
    • Dupre L, Aiuti A, Trifari S, Martino S, Saracco P, Bordignon C, Roncarolo MG (2002) Wiskott- Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. Immunity 17:157-166 (Pubitemid 35245958)
    • (2002) Immunity , vol.17 , Issue.2 , pp. 157-166
    • Dupre, L.1    Aiuti, A.2    Trifari, S.3    Martino, S.4    Saracco, P.5    Bordignon, C.6    Roncarolo, M.-G.7
  • 20
    • 57749120551 scopus 로고    scopus 로고
    • Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery
    • Dushek O, Mueller S, Soubies S, Depoil D, Caramalho I, Coombs D, Valitutti S (2008) Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery. PLoS ONE 3:e3913
    • (2008) PLoS ONE , vol.3
    • Dushek, O.1    Mueller, S.2    Soubies, S.3    Depoil, D.4    Caramalho, I.5    Coombs, D.6    Valitutti, S.7
  • 23
    • 33847419853 scopus 로고    scopus 로고
    • CD2 and TCR synergize for the activation of phospholipase Cγ1/calcium pathway at the immunological synapse
    • DOI 10.1093/intimm/dxl141
    • Espagnolle N, Depoil D, Zaru R, Demeur C, Champagne E, Guiraud M, Valitutti S (2007) CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse. Int Immunol 19:239-248 (Pubitemid 46344688)
    • (2007) International Immunology , vol.19 , Issue.3 , pp. 239-248
    • Espagnolle, N.1    Depoil, D.2    Zaru, R.3    Demeur, C.4    Champagne, E.5    Guiraud, M.6    Valitutti, S.7
  • 26
    • 0042847271 scopus 로고    scopus 로고
    • Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling
    • Faroudi M, Zaru R, Paulet P, Muller S, Valitutti S (2003b) Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling. J Immunol 171:1128-1132 (Pubitemid 36900039)
    • (2003) Journal of Immunology , vol.171 , Issue.3 , pp. 1128-1132
    • Faroudi, M.1    Zaru, R.2    Paulet, P.3    Muller, S.4    Valitutti, S.5
  • 28
    • 21844440052 scopus 로고    scopus 로고
    • Tuning immune responses: Diversity and adaptation of the immunological synapse
    • DOI 10.1038/nri1647
    • Friedl P, den Boer AT, Gunzer M (2005) Tuning immune responses: diversity and adaptation of the immunological synapse. Nat Rev Immunol 5:532-545 (Pubitemid 40961331)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.7 , pp. 532-545
    • Friedl, P.1    Den Boer, A.Th.2    Gunzer, M.3
  • 30
    • 38949137056 scopus 로고    scopus 로고
    • Making friends in out-of-the-way places: How cells of the immune system get together and how they conduct their business as revealed by intravital imaging
    • DOI 10.1111/j.1600-065X.2008.00591.x
    • Germain RN, Bajenoff M, Castellino F, Chieppa M, Egen JG, Huang AY, Ishii M, Koo LY, Qi H (2008) Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging. Immunol Rev 221:163-181 (Pubitemid 351230117)
    • (2008) Immunological Reviews , vol.221 , Issue.1 , pp. 163-181
    • Germain, R.N.1    Bajenoff, M.2    Castellino, F.3    Chieppa, M.4    Egen, J.G.5    Huang, A.Y.C.6    Ishii, M.7    Koo, L.Y.8    Qi, H.9
  • 32
    • 33847311403 scopus 로고    scopus 로고
    • Formins Regulate the Actin-Related Protein 2/3 Complex-Independent Polarization of the Centrosome to the Immunological Synapse
    • DOI 10.1016/j.immuni.2007.01.008, PII S1074761307001355
    • Gomez TS, Kumar K, Medeiros RB, Shimizu Y, Leibson PJ, Billadeau DD (2007) Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. Immunity 26:177-190 (Pubitemid 46329435)
    • (2007) Immunity , vol.26 , Issue.2 , pp. 177-190
    • Gomez, T.S.1    Kumar, K.2    Medeiros, R.B.3    Shimizu, Y.4    Leibson, P.J.5    Billadeau, DanielD.6
  • 33
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • DOI 10.1126/science.285.5425.221
    • Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML (1999) The immunological synapse: a molecular machine controlling T cell activation. Science 285:221-227 (Pubitemid 29329988)
    • (1999) Science , vol.285 , Issue.5425 , pp. 221-227
    • Grakoui, A.1    Bromley, S.K.2    Sumen, C.3    Davis, M.M.4    Shaw, A.S.5    Allen, P.M.6    Dustin, M.L.7
  • 34
    • 0033666324 scopus 로고    scopus 로고
    • Antigen presentation in extracellular matrix: Interactions of T cells with dendritic cells are dynamic, short lived, and sequential
    • Gunzer M, Schafer A, Borgmann S, Grabbe S, Zanker KS, Brocker EB, Kampgen E, Friedl P (2000) Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity 13:323-332
    • (2000) Immunity , vol.13 , pp. 323-332
    • Gunzer, M.1    Schafer, A.2    Borgmann, S.3    Grabbe, S.4    Zanker, K.S.5    Brocker, E.B.6    Kampgen, E.7    Friedl, P.8
  • 35
    • 34548012864 scopus 로고    scopus 로고
    • Plasma membrane segregation during T cell activation: probing the order of domains
    • DOI 10.1016/j.coi.2007.05.002, PII S0952791507000970
    • Harder T, Rentero C, Zech T, Gaus K (2007) Plasma membrane segregation during T cell activation: probing the order of domains. Curr Opin Immunol 19:470-475 (Pubitemid 47284850)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.4 , pp. 470-475
    • Harder, T.1    Rentero, C.2    Zech, T.3    Gaus, K.4
  • 37
    • 0346244099 scopus 로고    scopus 로고
    • T-cell-antigen recognition and the immunological synapse
    • Huppa JB, Davis MM (2003) T-cell-antigen recognition and the immunological synapse. Nat Rev Immunol 3:973-983
    • (2003) Nat Rev Immunol , vol.3 , pp. 973-983
    • Huppa, J.B.1    Davis, M.M.2
  • 39
    • 34447647655 scopus 로고    scopus 로고
    • Spatial and Temporal Dynamics of T Cell Receptor Signaling with a Photoactivatable Agonist
    • DOI 10.1016/j.immuni.2007.05.017, PII S1074761307003299
    • Huse M, Klein LO, Girvin AT, Faraj JM, Li QJ, Kuhns MS, Davis MM (2007) Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. Immunity 27:76-88 (Pubitemid 47089024)
    • (2007) Immunity , vol.27 , Issue.1 , pp. 76-88
    • Huse, M.1    Klein, L.O.2    Girvin, A.T.3    Faraj, J.M.4    Li, Q.-J.5    Kuhns, M.S.6    Davis, M.M.7
  • 40
    • 2342643498 scopus 로고    scopus 로고
    • A single class II myosin modulates T cell motility and stopping, but not synapse formation
    • DOI 10.1038/ni1065
    • Jacobelli J, Chmura SA, Buxton DB, Davis MM, Krummel MF (2004) A single class II myosin modulates T cell motility and stopping, but not synapse formation. Nat Immunol 5:531-538 (Pubitemid 38660466)
    • (2004) Nature Immunology , vol.5 , Issue.5 , pp. 531-538
    • Jacobelli, J.1    Chmura, S.A.2    Buxton, D.B.3    Davis, M.M.4    Krummel, M.F.5
  • 41
    • 38049136514 scopus 로고    scopus 로고
    • Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
    • Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD (2007) Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc Natl Acad Sci USA 104:20296-20301
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20296-20301
    • Kaizuka, Y.1    Douglass, A.D.2    Varma, R.3    Dustin, M.L.4    Vale, R.D.5
  • 42
    • 0034599541 scopus 로고    scopus 로고
    • Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
    • DOI 10.1083/jcb.149.1.181
    • Krause M, Sechi A, Konradt M, Monner D, Gertler F, Wehland J (2000) Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator- stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J Cell Biol 149:181-194 (Pubitemid 30196708)
    • (2000) Journal of Cell Biology , vol.149 , Issue.1 , pp. 181-194
    • Krause, M.1    Sechi, A.S.2    Konradt, M.3    Monner, D.4    Gertler, F.B.5    Wehland, J.6
  • 43
    • 0036199184 scopus 로고    scopus 로고
    • Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
    • DOI 10.1016/S1074-7613(02)00291-1
    • Krawczyk C, Oliveira-dos-Santos A, Sasaki T, Griffiths E, Ohashi PS, Snapper S, Alt F, Penninger JM (2002) Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity 16:331-343 (Pubitemid 34260912)
    • (2002) Immunity , vol.16 , Issue.3 , pp. 331-343
    • Krawczyk, C.1    Oliveira-Dos-Santos, A.2    Sasaki, T.3    Griffiths, E.4    Ohashi, P.S.5    Snapper, S.6    Alt, F.7    Penninger, J.M.8
  • 44
    • 0036166541 scopus 로고    scopus 로고
    • Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing
    • DOI 10.1016/S1074-7613(02)00262-5
    • Kuhn JR, Poenie M (2002) Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. Immunity 16:111-121 (Pubitemid 34143221)
    • (2002) Immunity , vol.16 , Issue.1 , pp. 111-121
    • Kuhn, J.R.1    Poenie, M.2
  • 48
    • 0034624809 scopus 로고    scopus 로고
    • Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes
    • DOI 10.1016/S0960-9822(00)00362-6
    • Leupin O, Zaru R, Laroche T, Muller S, Valitutti S (2000) Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes. Curr Biol 10:277-280 (Pubitemid 30152951)
    • (2000) Current Biology , vol.10 , Issue.5 , pp. 277-280
    • Leupin, O.1    Zaru, R.2    Laroche, T.3    Muller, S.4    Valitutti, S.5
  • 50
    • 4944266186 scopus 로고    scopus 로고
    • A role for the immunological synapse in lineage commitment of CD4 lymphocytes
    • DOI 10.1038/nature02916
    • Maldonado RA, Irvine DJ, Schreiber R, Glimcher LH (2004) A role for the immunological synapse in lineage commitment of CD4 lymphocytes. Nature 431:527-532 (Pubitemid 39336325)
    • (2004) Nature , vol.431 , Issue.7008 , pp. 527-532
    • Maldonade, R.A.1    Irvine, D.J.2    Schreiber, R.3    Glimcher, L.H.4
  • 51
    • 0035905308 scopus 로고    scopus 로고
    • The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis
    • DOI 10.1084/jem.194.12.1777
    • McGavin MK, Badour K, Hardy LA, Kubiseski TJ, Zhang J, Siminovitch KA (2001) The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis. J Exp Med 194:1777-1787 (Pubitemid 34028657)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.12 , pp. 1777-1787
    • McGavin, M.K.H.1    Badour, K.2    Hardy, L.A.3    Kubiseski, T.J.4    Zhang, J.5    Siminovitch, K.A.6
  • 52
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel TR, Henrickson SE, Von Andrian UH (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427:154-159
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    Von Andrian, U.H.3
  • 53
    • 0037036142 scopus 로고    scopus 로고
    • Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
    • DOI 10.1126/science.1070051
    • Miller MJ, Wei SH, Parker I, Cahalan MD (2002) Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296:1869-1873 (Pubitemid 34596273)
    • (2002) Science , vol.296 , Issue.5574 , pp. 1869-1873
    • Miller, M.J.1    Wei, S.H.2    Parker, I.3    Cahalan, M.D.4
  • 54
    • 5444229324 scopus 로고    scopus 로고
    • + T cell activation by dendritic cells in lymph nodes
    • DOI 10.1084/jem.20041236
    • Miller MJ, Safrina O, Parker I, Cahalan MD (2004) Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med 200:847-856 (Pubitemid 39362921)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.7 , pp. 847-856
    • Miller, M.J.1    Safrina, O.2    Parker, I.3    Cahalan, M.D.4
  • 55
    • 0027444915 scopus 로고
    • T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses
    • Molina IJ, Sancho J, Terhorst C, Rosen FS, Remold-ODonnell E (1993) T cells of patients with the Wiskott-Aldrich Syndrome have a restricted defect in proliferative responses. J Immunol 151:4383-4390 (Pubitemid 23298772)
    • (1993) Journal of Immunology , vol.151 , Issue.8 , pp. 4383-4390
    • Molina, I.J.1    Sancho, J.2    Terhorst, C.3    Rosen, F.S.4    Remold-O'Donnell, E.5
  • 56
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • DOI 10.1038/25764
    • Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82-86 (Pubitemid 28420234)
    • (1998) Nature , vol.395 , Issue.6697 , pp. 82-86
    • Monks, C.R.F.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 57
    • 0005448458 scopus 로고    scopus 로고
    • Polarity of T cell shape, motility, and sensitivity to antigen
    • DOI 10.1016/S1074-7613(00)80409-4
    • Negulescu PA, Krasieva TB, Khan A, Kerschbaum HH, Cahalan MD (1996) Polarity of T cell shape, motility, and sensitivity to antigen. Immunity 4:421-430 (Pubitemid 26354652)
    • (1996) Immunity , vol.4 , Issue.5 , pp. 421-430
    • Negulescu, P.A.1    Krasieva, T.B.2    Khan, A.3    Kerschbaum, H.H.4    Cahalan, M.D.5
  • 58
    • 44649191160 scopus 로고    scopus 로고
    • T Cell Costimulation via the Integrin VLA-4 Inhibits the Actin-Dependent Centralization of Signaling Microclusters Containing the Adaptor SLP-76
    • DOI 10.1016/j.immuni.2008.04.019, PII S1074761308002379
    • Nguyen K, Sylvain NR, Bunnell SC (2008) T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76. Immunity 28:810-821 (Pubitemid 351778409)
    • (2008) Immunity , vol.28 , Issue.6 , pp. 810-821
    • Nguyen, K.1    Sylvain, N.R.2    Bunnell, S.C.3
  • 59
    • 30044446991 scopus 로고    scopus 로고
    • The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation
    • DOI 10.1016/j.cub.2005.11.036, PII S0960982205014338
    • Nolz JC, Gomez TS, Zhu P, Li S, Medeiros RB, Shimizu Y, Burkhardt JK, Freedman BD, Billadeau DD (2006) The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation. Curr Biol 16:24-34 (Pubitemid 43049883)
    • (2006) Current Biology , vol.16 , Issue.1 , pp. 24-34
    • Nolz, J.C.1    Gomez, T.S.2    Zhu, P.3    Li, S.4    Medeiros, R.B.5    Shimizu, Y.6    Burkhardt, J.K.7    Freedman, B.D.8    Billadeau, D.D.9
  • 60
    • 0021175671 scopus 로고
    • A synaptic basis for T-lymphocyte activation
    • Norcross M (1984) A synaptic basis for T-lymphocyte activation. Ann Immunol (Paris) 135D:113-134 (Pubitemid 14024063)
    • (1984) Annales d'Immunologie , vol.135 , Issue.2 , pp. 113-134
    • Norcross, M.A.1
  • 64
    • 0345086416 scopus 로고    scopus 로고
    • Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: Role of calpain proteolytic pathway
    • Penna D, Muller S, Martinon F, Demotz S, Iwashima M, Valitutti S (1999) Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway. J Immunol 163:50-56 (Pubitemid 29295823)
    • (1999) Journal of Immunology , vol.163 , Issue.1 , pp. 50-56
    • Penna, D.1    Muller, S.2    Martinon, F.3    Demotz, S.4    Iwashima, M.5    Valitutti, S.6
  • 65
    • 2442651482 scopus 로고    scopus 로고
    • T cell killing does not require the formation of a stable mature immunological synapse
    • Purbhoo MA, Irvine DJ, Huppa JB, Davis MM (2004) T cell killing does not require the formation of a stable mature immunological synapse. Nat Immunol 5:524-530
    • (2004) Nat Immunol , vol.5 , pp. 524-530
    • Purbhoo, M.A.1    Irvine, D.J.2    Huppa, J.B.3    Davis, M.M.4
  • 66
    • 0036225013 scopus 로고    scopus 로고
    • Imaging synapse formation during thymocyte selection: Inability of CD3zeta to form a stable central accumulation during negative selection
    • Richie LI, Ebert PJ, Wu LC, Krummel MF, Owen JJ, Davis MM (2002) Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selection. Immunity 16:595-606
    • (2002) Immunity , vol.16 , pp. 595-606
    • Richie, L.I.1    Ebert, P.J.2    Wu, L.C.3    Krummel, M.F.4    Owen, J.J.5    Davis, M.M.6
  • 67
    • 0036928182 scopus 로고    scopus 로고
    • Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation
    • DOI 10.1016/S1097-2765(02)00728-1
    • Sasahara Y, Rachid R, Byrne MJ, de la Fuente MA, Abraham RT, Ramesh N, Geha RS (2002) Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Mol Cell 10:1269-1281 (Pubitemid 36050870)
    • (2002) Molecular Cell , vol.10 , Issue.6 , pp. 1269-1281
    • Sasahara, Y.1    Rachid, R.2    Byrne, M.J.3    De La Fuente, M.A.4    Abraham, R.T.5    Ramesh, N.6    Geha, R.S.7
  • 70
    • 0025182959 scopus 로고
    • Adhesion receptors of the immune system
    • Springer TA (1990) Adhesion receptors of the immune system. Nature 346:425-434 (Pubitemid 120005914)
    • (1990) Nature , vol.346 , Issue.6283 , pp. 425-434
    • Springer, T.A.1
  • 71
    • 0035655587 scopus 로고    scopus 로고
    • The immunological synapse of CTL contains a secretory domain and membrane bridges
    • DOI 10.1016/S1074-7613(01)00234-5
    • Stinchcombe JC, Bossi G, Booth S, Griffiths GM (2001) The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 15:751-761 (Pubitemid 34008503)
    • (2001) Immunity , vol.15 , Issue.5 , pp. 751-761
    • Stinchcombe, J.C.1    Bossi, G.2    Booth, S.3    Griffiths, G.M.4
  • 72
    • 33749185296 scopus 로고    scopus 로고
    • Centrosome polarization delivers secretory granules to the immunological synapse
    • DOI 10.1038/nature05071, PII NATURE05071
    • Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM (2006) Centrosome polarization delivers secretory granules to the immunological synapse. Nature 443:462-465 (Pubitemid 44477283)
    • (2006) Nature , vol.443 , Issue.7110 , pp. 462-465
    • Stinchcombe, J.C.1    Majorovits, E.2    Bossi, G.3    Fuller, S.4    Griffiths, G.M.5
  • 73
    • 0037036114 scopus 로고    scopus 로고
    • Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
    • DOI 10.1126/science.1071065
    • Stoll S, Delon J, Brotz TM, Germain RN (2002) Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296:1873-1876 (Pubitemid 34596274)
    • (2002) Science , vol.296 , Issue.5574 , pp. 1873-1876
    • Stoll, S.1    Delon, J.2    Brotz, T.M.3    Germain, R.N.4
  • 74
    • 33646468223 scopus 로고    scopus 로고
    • Regulatory T cells inhibit protein kinase C theta recruitment to the immune synapse of naive T cells with the same antigen specificity
    • Sumoza-Toledo A, Eaton AD, Sarukhan A (2006) Regulatory T cells inhibit protein kinase C theta recruitment to the immune synapse of naive T cells with the same antigen specificity. J Immunol 176:5779-5787
    • (2006) J Immunol , vol.176 , pp. 5779-5787
    • Sumoza-Toledo, A.1    Eaton, A.D.2    Sarukhan, A.3
  • 76
    • 33845729059 scopus 로고    scopus 로고
    • The WASP-WAVE protein network: Connecting the membrane to the cytoskeleton
    • DOI 10.1038/nrm2069, PII NRM2069
    • Takenawa T, Suetsugu S (2007) The WASP-WAVE protein network: connecting the membrane to the cytoskeleton. Nat Rev Mol Cell Biol 8:37-48 (Pubitemid 46012013)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.1 , pp. 37-48
    • Takenawa, T.1    Suetsugu, S.2
  • 77
    • 0037716822 scopus 로고    scopus 로고
    • The diversity of immunological synapses
    • DOI 10.1016/S0952-7915(03)00040-2
    • Trautmann A, Valitutti S (2003) The diversity of immunological synapses. Curr Opin Immunol 15:249-254 (Pubitemid 36645100)
    • (2003) Current Opinion in Immunology , vol.15 , Issue.3 , pp. 249-254
    • Trautmann, A.1    Valitutti, S.2
  • 79
    • 0042931251 scopus 로고    scopus 로고
    • Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization
    • Tskvitaria-Fuller I, Rozelle AL, Yin HL, Wulfing C (2003) Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization. J Immunol 171:2287-2295 (Pubitemid 37025533)
    • (2003) Journal of Immunology , vol.171 , Issue.5 , pp. 2287-2295
    • Tskvitaria-Fuller, I.1    Rozelle, A.L.2    Yin, H.L.3    Wulfing, C.4
  • 80
    • 51549097744 scopus 로고    scopus 로고
    • Immunological synapse: Center of attention again
    • Valitutti S (2008) Immunological synapse: center of attention again. Immunity 29:384-386
    • (2008) Immunity , vol.29 , pp. 384-386
    • Valitutti, S.1
  • 81
    • 0028961573 scopus 로고
    • Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
    • Valitutti S, Dessing M, Aktories K, Gallati H, Lanzavecchia A (1995) Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J Exp Med 181:577-584
    • (1995) J Exp Med , vol.181 , pp. 577-584
    • Valitutti, S.1    Dessing, M.2    Aktories, K.3    Gallati, H.4    Lanzavecchia, A.5
  • 82
    • 0030002902 scopus 로고    scopus 로고
    • Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
    • DOI 10.1084/jem.183.4.1917
    • Valitutti S, Muller S, Dessing M, Lanzavecchia A (1996a) Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J Exp Med 183:1917-1921 (Pubitemid 26134333)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.4 , pp. 1917-1921
    • Valitutti, S.1    Muller, S.2    Dessing, M.3    Lanzavecchia, A.4
  • 83
    • 0029797674 scopus 로고    scopus 로고
    • Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates
    • Valitutti S, Muller S, Dessing M, Lanzavecchia A (1996b) Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur J Immunol 26:2012-2016 (Pubitemid 26297495)
    • (1996) European Journal of Immunology , vol.26 , Issue.9 , pp. 2012-2016
    • Valitutti, S.1    Muller, S.2    Dessing, M.3    Lanzavecchia, A.4
  • 84
    • 33746011209 scopus 로고    scopus 로고
    • T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster
    • DOI 10.1016/j.immuni.2006.04.010, PII S1074761306002974
    • Varma R, Campi G, Yokosuka T, Saito T, Dustin ML (2006) T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25:117-127 (Pubitemid 44066825)
    • (2006) Immunity , vol.25 , Issue.1 , pp. 117-127
    • Varma, R.1    Campi, G.2    Yokosuka, T.3    Saito, T.4    Dustin, M.L.5
  • 85
    • 33747050163 scopus 로고    scopus 로고
    • T cells and their partners: the chemokine dating agency
    • DOI 10.1016/j.it.2006.07.004, PII S1471490606002146
    • Viola A, Contento RL, Molon B (2006) T cells and their partners: the chemokine dating agency. Trends Immunol 27:421-427 (Pubitemid 44216192)
    • (2006) Trends in Immunology , vol.27 , Issue.9 , pp. 421-427
    • Viola, A.1    Contento, R.L.2    Molon, B.3
  • 86
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, Cui K, Kanno Y, Roh TY, Watford WT et al (2009) Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 30:155-167
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6    Cui, K.7    Kanno, Y.8    Roh, T.Y.9    Watford, W.T.10
  • 88
    • 44549088283 scopus 로고    scopus 로고
    • The concept of brain plasticity - Paillards systemic analysis and emphasis on structure and function (followed by the translation of a seminal paper by Paillard on plasticity
    • Will B, Dalrymple-Alford J, Wolff M, Cassel JC (2008) The concept of brain plasticity - Paillards systemic analysis and emphasis on structure and function (followed by the translation of a seminal paper by Paillard on plasticity). Behav Brain Res 192:2-7
    • (2008) Behav Brain Res , vol.192 , pp. 2-7
    • Will, B.1    Dalrymple-Alford, J.2    Wolff, M.3    Cassel, J.C.4
  • 89
    • 0036568944 scopus 로고    scopus 로고
    • Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site
    • Zaru R, Cameron TO, Stern LJ, Muller S, Valitutti S (2002) Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site. J Immunol 168:4287-4291 (Pubitemid 34441327)
    • (2002) Journal of Immunology , vol.168 , Issue.9 , pp. 4287-4291
    • Zaru, R.1    Cameron, T.O.2    Stern, L.J.3    Muller, S.4    Valitutti, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.