Pathogenesis of cholestatic liver disease and therapeutic approaches

Gastroenterology

Volumn 139, Issue 5, 2010, Pages 1481-1496

  Hirschfield, Gideon M ^a,b   Heathcote, E Jenny ^a,b   Gershwin, M Eric ^c  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cholestasis; Primary Biliary Cirrhosis; Primary Sclerosing Cholangitis; Ursodeoxycholic Acid

Indexed keywords

AZATHIOPRINE; BEZAFIBRATE; BILE ACID; BUDESONIDE; COLCHICINE; CYCLOSPORIN; FARNESOID X RECEPTOR; FENOFIBRATE; HORMONE RECEPTOR STIMULATING AGENT; INT 747; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; JAGGED1; LAMIVUDINE PLUS ZIDOVUDINE; METHOTREXATE; MINOCYCLINE; MOEXIPRIL; MONOCYTE CHEMOTACTIC PROTEIN 1; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NOTCH2 RECEPTOR; PENICILLAMINE; PREDNISONE; RITUXIMAB; TAMOXIFEN; TETRATHIOMOLYBDATE AMMONIUM; TETRATHIOMOLYBDIC ACID; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID; VANCOMYCIN;

ALAGILLE SYNDROME; APOPTOSIS; AUTOIMMUNE DISEASE; BILE ACID SYNTHESIS; BILE DUCT; BILE DUCT ATRESIA; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL PROLIFERATION; CHOLANGIOGRAPHY; CHOLESTASIS; CYTOKINE PRODUCTION; CYTOLOGY; FIBROGENESIS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; INFLAMMATION; INNATE IMMUNITY; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; NECROSIS; OXIDATION; PATHOGENESIS; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SEX DIFFERENCE; TH1 CELL; TH17 CELL; TH2 CELL;

EID: 78049486376     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.09.004     Document Type: Review

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