Pathology of immune-mediated liver injury

Digestive Diseases

Volumn 28, Issue 1, 2010, Pages 57-62

  Dienes, Hans Peter ^a   Drebber, Uta ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Histology of autoimmune liver disease; Histopathology; Histopathology of viral hepatitis; Toxic liver injury

Indexed keywords

CARBON TETRACHLORIDE; CD8 ANTIGEN; EPITOPE; FAS ANTIGEN; FAS LIGAND; HALOTHANE; PROGRAMMED DEATH 1 RECEPTOR;

AUTOIMMUNE HEPATITIS; BYSTANDER EFFECT; CD8+ T LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; DELTA AGENT HEPATITIS; EFFECTOR CELL; EPSTEIN BARR VIRUS INFECTION; HEPATITIS A; HEPATITIS B; HEPATITIS C; HISTOPATHOLOGY; HUMAN; IMMUNOPATHOGENESIS; IMMUNOPATHOLOGY; LIVER CELL DAMAGE; LIVER INJURY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; TOXIC HEPATITIS;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DRUG-INDUCED LIVER INJURY; HEPATITIS, AUTOIMMUNE; HEPATITIS, VIRAL, HUMAN; HUMANS; IMMUNITY, INNATE; LIVER; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; NATURAL KILLER T-CELLS; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, REGULATORY;

EID: 77952575494     PISSN: 02572753     EISSN: None     Source Type: Journal    
DOI: 10.1159/000282065     Document Type: Review

References (20)

1. Crispe IN: The liver as a lymphoid organ. Annu Rev Immunol 2009;27:147-163.
2. Zimmerman HJ: Hepatoxicity: The Adverse Effects of Drugs and Other Chemicals on the Liver. Philadelphia, Lippinkott Williams & Wilkins, 1999.
3. Lewis JH, Kleiner DE: Hepatic injury due to drugs, chemicals and toxins;in MacSween RNM, Burt AD, Portmann B, Ferrell LD: MacSween's Pathology of the Liver. New York, Churchill Livingstone Elsevier, 2007, pp 649-760.
4. Park O, et al: Diverse roles ofinvariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride. Hepatology 2009;49:1683-1694.
5. Gunawan BK, Kaplowitz N: Mechanisms of drug-induced liver disease. Clin Liver Dis 2007;11:459-475, v.
6. Feinstone SM, et al: Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness. Science 1973;182:1026-1028.
7. Fleischer B, et al: Clonal analysis ofinfiltrating T lymphocytes in liver tissue in viral hepatitis A. Immunology 1990;69:14-19.
8. Chisari FV, et al: A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science 1985;230:1157-1160.
9. Rizzetto M, et al: Immunofluorescence detection of new antigen-antibody system (delta/anti-delta) associated to hepatitis B virus in liver and in serum of HBsAg carriers. Gut 1977;18:997-1003.
10. Zachou K, et al: Quantitative HBsAg and HDV-RNA levels in chronic delta hepatitis. Liver Int 2009, E-pub ahead of print.
11. Dienes HP, et al: Liver biopsy in hepatitis C. J Hepatol 1999;31(suppl 1):43-46.
12. Wang AG, et al: Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J Pathol 2009;219:253-262.
13. Rehermann B: Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence. J Clin Invest 2009;119:1745-1754.
14. Thimme R, et al: CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J Virol 2003;77:68-76.
15. Thimme R, et al: Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease. Proc Natl Acad Sci USA 2002;99:15661-15668.
16. Johnson LD, Jameson SC: Immunology. A chronic need for IL-21. Science 2009;324:1525-1526.
17. Drebber U, et al: The role of Epstein-Barr virus in acute and chronic hepatitis. J Hepatol 2006;44:879-885.
18. Lohse AW, et al: Suppression of murine experimental autoimmune hepatitis by T-cell vaccination or immunosuppression. Hepatology 1998;27:1536-1543.
19. Meyer zum Büschenfelde KH, et al: Experimental chronic active hepatitis in rabbits following immunization with human liver proteins. Clin Exp Immunol 1972;11:99-108.
20. Dienes H P, et al: Histologic features in autoimmune hepatitis. Z Gastroenterol 1989;27:325-330.