메뉴 건너뛰기




Volumn 105, Issue 31, 2008, Pages 10895-10900

Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease

Author keywords

Cholangitis; Primary sclerosing cholangitis

Indexed keywords

DEATH RECEPTOR 5; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DEATH RECEPTOR 5;

EID: 49449097533     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802702105     Document Type: Article
Times cited : (120)

References (43)
  • 1
    • 1642300863 scopus 로고    scopus 로고
    • The role of TNF and its family members in inflammation and cancer: Lessons from gene deletion
    • Aggarwal BB, Shishodia S, Ashikawa K, Bharti AC (2002) The role of TNF and its family members in inflammation and cancer: lessons from gene deletion. Current Drug Targets 1:327-341.
    • (2002) Current Drug Targets , vol.1 , pp. 327-341
    • Aggarwal, B.B.1    Shishodia, S.2    Ashikawa, K.3    Bharti, A.C.4
  • 2
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 3
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumour-necrosis factor superfamily
    • Ashkenazi A (2002) Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer 2:420-430.
    • (2002) Nat Rev Cancer , vol.2 , pp. 420-430
    • Ashkenazi, A.1
  • 4
    • 14544288632 scopus 로고    scopus 로고
    • + T-cell memory via TRAIL-mediated activation-induced cell death
    • + T-cell memory via TRAIL-mediated activation-induced cell death. Nature 434:88-93.
    • (2005) Nature , vol.434 , pp. 88-93
    • Janssen, E.M.1
  • 6
    • 35948941870 scopus 로고    scopus 로고
    • H2 cells and the expression of allergic airway disease
    • H2 cells and the expression of allergic airway disease. Nat Med 13:1308-1315.
    • (2007) Nat Med , vol.13 , pp. 1308-1315
    • Weckmann, M.1
  • 7
    • 0035137696 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
    • Takeda K, et al. (2001) Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 7:94-100.
    • (2001) Nat Med , vol.7 , pp. 94-100
    • Takeda, K.1
  • 8
    • 0037148518 scopus 로고    scopus 로고
    • Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
    • Takeda K, et al. (2002) Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J Exp Med 195:161-169.
    • (2002) J Exp Med , vol.195 , pp. 161-169
    • Takeda, K.1
  • 10
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand
    • Ashkenazi A, et al. (1999) Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 104:155-162.
    • (1999) J Clin Invest , vol.104 , pp. 155-162
    • Ashkenazi, A.1
  • 11
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5:157-163.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1
  • 12
    • 0035871757 scopus 로고    scopus 로고
    • Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
    • Chuntharapai A, et al. (2001) Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4. J Immunol 166:4891-4898.
    • (2001) J Immunol , vol.166 , pp. 4891-4898
    • Chuntharapai, A.1
  • 13
    • 17944376030 scopus 로고    scopus 로고
    • Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
    • Ichikawa K, et al. (2001) Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 7:954-960.
    • (2001) Nat Med , vol.7 , pp. 954-960
    • Ichikawa, K.1
  • 14
    • 10744220151 scopus 로고    scopus 로고
    • Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy
    • Takeda K, et al. (2004) Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy. J Exp Med 199:437-448.
    • (2004) J Exp Med , vol.199 , pp. 437-448
    • Takeda, K.1
  • 15
    • 34248187996 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1
    • Tolcher AW, et al. (2007) Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1. J Clin Oncol 25:1390-1395.
    • (2007) J Clin Oncol , vol.25 , pp. 1390-1395
    • Tolcher, A.W.1
  • 16
    • 35948952826 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
    • Plummer R, et al. (2007) Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers. Clin Cancer Res 13:6187-6194.
    • (2007) Clin Cancer Res , vol.13 , pp. 6187-6194
    • Plummer, R.1
  • 17
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S (1997) Essential roles of the Fas ligand in the development of hepatitis. Nat Med 3:409-413.
    • (1997) Nat Med , vol.3 , pp. 409-413
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 18
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, et al. (2000) Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 6:564-567.
    • (2000) Nat Med , vol.6 , pp. 564-567
    • Jo, M.1
  • 19
    • 0035050960 scopus 로고    scopus 로고
    • Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
    • Lawrence D, et al. (2001) Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 7:383-385.
    • (2001) Nat Med , vol.7 , pp. 383-385
    • Lawrence, D.1
  • 20
    • 0742272016 scopus 로고    scopus 로고
    • Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2
    • Mori E, et al. (2004) Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2. Cell Death Differ 11:203-207.
    • (2004) Cell Death Differ , vol.11 , pp. 203-207
    • Mori, E.1
  • 21
    • 36348941705 scopus 로고    scopus 로고
    • Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver
    • Volkmann X, et al. (2007) Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver. Hepatology 46:1498-1508.
    • (2007) Hepatology , vol.46 , pp. 1498-1508
    • Volkmann, X.1
  • 23
    • 0036127860 scopus 로고    scopus 로고
    • Management of primary sclerosing cholangitis
    • Lee YM, Kaplan MM (2002) Management of primary sclerosing cholangitis. Am J Gastroenterol 97:528-534.
    • (2002) Am J Gastroenterol , vol.97 , pp. 528-534
    • Lee, Y.M.1    Kaplan, M.M.2
  • 24
    • 0037218038 scopus 로고    scopus 로고
    • Current management of primary biliary cirrhosis and primary sclerosing cholangitis
    • Levy C, Lindor KD (2003) Current management of primary biliary cirrhosis and primary sclerosing cholangitis. J Hepatol 38 Suppl 1:S24-S37.
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. 1
    • Levy, C.1    Lindor, K.D.2
  • 26
    • 0033607006 scopus 로고    scopus 로고
    • Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
    • Yin XM, et al. (1999) Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 400:886-891.
    • (1999) Nature , vol.400 , pp. 886-891
    • Yin, X.M.1
  • 27
    • 0037174864 scopus 로고    scopus 로고
    • TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid
    • Werner AB, de Vries E, Tait SWG, Bontjer I, Borst J (2002) TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid. J Biol Chem 277:40760-40767.
    • (2002) J Biol Chem , vol.277 , pp. 40760-40767
    • Werner, A.B.1    de Vries, E.2    Tait, S.W.G.3    Bontjer, I.4    Borst, J.5
  • 28
    • 4544253226 scopus 로고    scopus 로고
    • Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity
    • Ricci MS, et al. (2004) Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. Mol Cell Biol 24:8541-8555.
    • (2004) Mol Cell Biol , vol.24 , pp. 8541-8555
    • Ricci, M.S.1
  • 29
    • 1542466794 scopus 로고    scopus 로고
    • Critical roles of TRAIL in hepatic cell death and hepatic inflammation
    • Zheng SJ, Wang P, Tsabary G, Chen YH (2004) Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J Clin Invest 113:58-64.
    • (2004) J Clin Invest , vol.113 , pp. 58-64
    • Zheng, S.J.1    Wang, P.2    Tsabary, G.3    Chen, Y.H.4
  • 30
    • 9244237679 scopus 로고    scopus 로고
    • TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
    • Hao C, et al. (2004) TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res 64:8502-8506.
    • (2004) Cancer Res , vol.64 , pp. 8502-8506
    • Hao, C.1
  • 32
    • 0036827808 scopus 로고    scopus 로고
    • Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity
    • Higuchi H, Bronk SF, Taniai M, Canbay A, Gores GJ (2002) Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther 303:461-467.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 461-467
    • Higuchi, H.1    Bronk, S.F.2    Taniai, M.3    Canbay, A.4    Gores, G.J.5
  • 33
    • 42249091320 scopus 로고    scopus 로고
    • TRAIL mediated liver injury by the innate immune systems in the bile duct-lagated mice
    • Kahraman A, et al. (2008) TRAIL mediated liver injury by the innate immune systems in the bile duct-lagated mice. Hepatology 47:1317-1330.
    • (2008) Hepatology , vol.47 , pp. 1317-1330
    • Kahraman, A.1
  • 34
    • 33748931670 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis: Summary of a workshop
    • LaRusso NF, et al. (2006) Primary sclerosing cholangitis: summary of a workshop. Hepatology 44:746-764.
    • (2006) Hepatology , vol.44 , pp. 746-764
    • LaRusso, N.F.1
  • 35
    • 10644245899 scopus 로고    scopus 로고
    • + gut-homing lymphocytes to the liver in primary sclerosing cholangitis
    • + gut-homing lymphocytes to the liver in primary sclerosing cholangitis. J Exp Med 200:1511-1517.
    • (2004) J Exp Med , vol.200 , pp. 1511-1517
    • Eksteen, B.1
  • 36
    • 16244409253 scopus 로고    scopus 로고
    • Interferons as pathogenic effectors in autoimmunity
    • Baccala R, Kono DH, Theofilopoulos AN (2005) Interferons as pathogenic effectors in autoimmunity. Immunol Rev 204:9-26.
    • (2005) Immunol Rev , vol.204 , pp. 9-26
    • Baccala, R.1    Kono, D.H.2    Theofilopoulos, A.N.3
  • 37
    • 0033519303 scopus 로고    scopus 로고
    • Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs
    • Kayagaki N, et al. (1999) Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs. J Exp Med 189:1451-1460.
    • (1999) J Exp Med , vol.189 , pp. 1451-1460
    • Kayagaki, N.1
  • 38
    • 84889271499 scopus 로고    scopus 로고
    • IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
    • Fulda S, Debatin KM (2002) IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 21:2295-2308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 39
    • 36349035570 scopus 로고    scopus 로고
    • Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia
    • Harada K et al. (2007) Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia. Hepatology 46:1146-1154.
    • (2007) Hepatology , vol.46 , pp. 1146-1154
    • Harada, K.1
  • 40
    • 0036296996 scopus 로고    scopus 로고
    • High frequency of autoantibodies in patients with primary sclerosing cholangitis that bind biliary epithelial cells and induce expression of CD44 and production of interleukin 6
    • Xu B, Broome U, Ericzon BG, Sumitran-Holgersson S (2002) High frequency of autoantibodies in patients with primary sclerosing cholangitis that bind biliary epithelial cells and induce expression of CD44 and production of interleukin 6. Gut 51:120-127.
    • (2002) Gut , vol.51 , pp. 120-127
    • Xu, B.1    Broome, U.2    Ericzon, B.G.3    Sumitran-Holgersson, S.4
  • 43
    • 0031978211 scopus 로고    scopus 로고
    • Isolation, culture and characterization of biliary epithelial cells from different anatomical levels of the intrahepatic and extrahepatic biliary tree from a mouse
    • Katayanagi K, Kono N, Nakanuma Y (1998) Isolation, culture and characterization of biliary epithelial cells from different anatomical levels of the intrahepatic and extrahepatic biliary tree from a mouse. Liver 18:90-98.
    • (1998) Liver , vol.18 , pp. 90-98
    • Katayanagi, K.1    Kono, N.2    Nakanuma, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.