Phylogenetic and immunological definition of four lipoylated proteins from Novosphingobium aromaticivorans, implications for primary biliary cirrhosis

Journal of Autoimmunity

Volumn 24, Issue 3, 2005, Pages 209-219

  Padgett, Kerstien A ^a   Selmi, Carlo ^a,b   Kenny, Thomas P ^a   Leung, Patrick S C ^a   Balkwill, David L ^c   Ansari, Aftab A ^d   Coppel, Ross L ^e   Gershwin, M Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c FLORIDA STATE UNIVERSITY   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MONASH UNIVERSITY   (Australia)

Author keywords

Lipoic acid; Molecular mimicry; Protein homology; Pyruvate dehydrogenase

Indexed keywords

AMINO ACID; AUTOANTIGEN; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; MITOCHONDRIAL PROTEIN; MONOCLONAL ANTIBODY; NOVO 1 PROTEIN; NOVO 2 PROTEIN; NOVO 3 PROTEIN; NOVO 4 PROTEIN; RABBIT ANTISERUM; THIOCTIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIUM; CONTROLLED STUDY; GENE SEQUENCE; IMMUNOLOGY; IMMUNOREACTIVITY; MOLECULAR CLONING; NONHUMAN; NOVOSPHINGOBIUM AROMATICIVORANS; PHYLOGENY; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; SEQUENCE HOMOLOGY;

EID: 17444431516     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaut.2005.01.012     Document Type: Article

References (34)

1. J.A. Talwalkar, and K.D. Lindor Primary biliary cirrhosis Lancet 362 2003 53 61
2. M.E. Gershwin, A.A. Ansari, I.R. Mackay, Y. Nakanuma, A. Nishio, and M.J. Rowley Primary biliary cirrhosis: an orchestrated immune response against epithelial cells Immunol Rev 174 2000 210 225
3. C. Selmi, M.J. Mayo, N. Bach, H. Ishibashi, P. Invernizzi, and R.G. Gish Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment Gastroenterology 127 2004 485 492
4. P.S. Leung, C. Quan, O. Park, J. Van de Water, M.J. Kurth, and M.H. Nantz Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies J Immunol 170 2003 5326 5332
5. J. Van de Water, H. Ishibashi, R.L. Coppel, and M.E. Gershwin Molecular mimicry and primary biliary cirrhosis: premises not promises Hepatology 33 2001 771 775
6. M. Takeuchi, K. Hamana, and A. Hiraishi Proposal of the genus Sphingomonas sensu stricto and three new genera. Sphingobium, Novosphingobium and Sphingopyxis, on the basis of phylogenetic and chemotaxonomic analyses Int J Syst Evol Microbiol 51 2001 1405 1417
7. D.L. Balkwill, G.R. Drake, R.H. Reeves, J.K. Fredrickson, D.C. White, and D.B. Ringelberg Taxonomic study of aromatic-degrading bacteria from deep-terrestrial-subsurface sediments and description of Sphingomonas aromaticivorans sp. nov., Sphingomonas subterranea sp. nov., Sphingomonas stygia sp. nov Int J Syst Bacteriol 47 1997 191 201
8. K. Fujii, S. Kikuchi, M. Satomi, N. Ushio-Sata, and N. Morita Degradation of 17beta-estradiol by a gram-negative bacterium isolated from activated sludge in a sewage treatment plant in Tokyo Japan. Appl Environ Microbiol 68 2002 2057 2060
9. C. Selmi, D.L. Balkwill, P. Invernizzi, A.A. Ansari, R.L. Coppel, and M. Podda Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium Hepatology 38 2003 1250 1257
10. S.P. Fussey, S.T. Ali, J.R. Guest, O.F. James, M.F. Bassendine, and S.J. Yeaman Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region Proc Natl Acad Sci USA 87 1990 3987 3991
11. A.S. Abdulkarim, L.M. Petrovic, W.R. Kim, P. Angulo, R.V. Lloyd, and K.D. Lindor Primary biliary cirrhosis: an infectious disease caused by Chlamydia pneumoniae? J Hepatol 40 2004 380 384
12. P. Muratori, L. Muratori, M. Guidi, S. Maccariello, G. Pappas, and R. Ferrari Anti-Saccharomyces cerevisiae antibodies (ASCA) and autoimmune liver diseases Clin Exp Immunol 132 2003 473 476
13. H. Miyakawa, A. Tanaka, K. Kikuchi, M. Matsushita, E. Kitazawa, and N. Kawaguchi Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens Hepatology 34 2001 243 248
14. C. Selmi, and M.E. Gershwin Bacteria and human autoimmunity: the case of primary biliary cirrhosis Curr Opin Rheumatol 16 2004 406 410
15. S. Olafsson, H. Gudjonsson, C. Selmi, K. Amano, P. Invernizzi, and M. Podda Antimitochondrial antibodies and reactivity to N. aromaticivorans proteins in Icelandic patients with primary biliary cirrhosis and their relatives Am J Gastroenterol 99 2004 2143 2146
16. S.F. Bruggraber, P.S. Leung, K. Amano, C. Quan, M.J. Kurth, and M.H. Nantz Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis Gastroenterology 125 2003 1705 1713
17. J.M. Palmer, A.J. Robe, A.D. Burt, J.A. Kirby, and D.E. Jones Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse Hepatology 39 2004 1583 1592
18. M.D. Van Norstrand, M. Malinchoc, K.D. Lindor, T.M. Therneau, M.E. Gershwin, and P.S. Leung Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in patients with primary biliary cirrhosis: relationship of levels of autoantibodies to disease progression Hepatology 25 1997 6 11
19. F.P. Vleggaar, and H.R. van Buuren No prognostic significance of antimitochondrial antibody profile testing in primary biliary cirrhosis Hepatogastroenterology 51 2004 937 940
20. C. Vitali, W. Bencivelli, D.A. Isenberg, J.S. Smolen, M.L. Snaith, and M. Sciuto Disease activity in systemic lupus erythematosus: report of the Consensus Study Group of the European Workshop for Rheumatology Research. II. Identification of the variables indicative of disease activity and their use in the development of an activity score. The European Consensus Study Group for Disease Activity in SLE Clin Exp Rheumatol 10 1992 541 547
21. M.L. Souan, M. Geffard, J. Vieillemaringe, P. Lebrun-Grandie, and J.M. Orgogozo Anti-acetylcholine antibodies and the pathogenesis of myasthenia gravis Ann N Y Acad Sci 505 1987 423 438
22. A. Falorni, and F. Calcinaro Humoral responses in type 1 diabetes mellitus Rev Endocr Metab Disord 4 2003 281 290
23. J. Orgiazzi Anti-TSH receptor antibodies in clinical practice Endocrinol Metab Clin North Am 29 2000 339 355 vii
24. H. Kita, M. Imawari, and M.E. Gershwin Cellular immune response in primary biliary cirrhosis Hepatol Res 28 2004 12 17
25. J.V. Metcalf, H.C. Mitchison, J.M. Palmer, D.E. Jones, M.F. Bassendine, and O.F. James Natural history of early primary biliary cirrhosis Lancet 348 1996 1399 1402
26. A. Mattalia, S. Quaranta, P.S. Leung, M. Bauducci, J. Van de Water, and P.L. Calvo Characterization of antimitochondrial antibodies in health adults Hepatology 27 1998 656 661
27. L. Xu, Z. Shen, L. Guo, B. Fodera, A. Keogh, and R. Joplin Does a betaretrovirus infection trigger primary biliary cirrhosis? Proc Natl Acad Sci USA 100 2003 8454 8459
28. C. Selmi, S.R. Ross, A.A. Ansari, P. Invernizzi, M. Podda, and R.L. Coppel Lack of immunological or molecular evidence for a role of mouse mammary tumor retrovirus in primary biliary cirrhosis Gastroenterology 127 2004 493 501
29. T. Shi, J.K. Fredrickson, and D.L. Balkwill Biodegradation of polycyclic aromatic hydrocarbons by Sphingomonas strains isolated from the terrestrial subsurface J Ind Microbiol Biotechnol 26 2001 283 289
30. A. Nishio, E.B. Keeffe, and M.E. Gershwin Immunopathogenesis of primary biliary cirrhosis Semin Liver Dis 22 2002 291 302
31. S.A. Long, C. Quan, J. Van de Water, M.H. Nantz, M.J. Kurth, and D. Barsky Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis J Immunol 167 2001 2956 2963
32. N. Fukushima, G. Nalbandian, J. Van de Water, K. White, A.A. Ansari, and P. Leung Characterization of recombinant monoclonal IgA anti-PDC-E2 autoantibodies derived from patients with PBC Hepatology 36 2002 1383 1392
33. J.A. Odin, R.C. Huebert, L. Casciola-Rosen, N.F. LaRusso, and A. Rosen Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis J Clin Invest 108 2001 223 232
34. S. Matsumura, J. Van de Water, H. Kita, R.L. Coppel, T. Tsuji, and K. Yamamoto Contribution to antimitochondrial antibody production: cleavage of pyruvate dehydrogenase complex-E2 by apoptosis-related proteases Hepatology 35 2002 14 22