-
1
-
-
0141885079
-
Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway
-
Alam J, Deharo D, Redding KM, Re RN, and Cook JL. Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway. Curr Pharm Des 9: 2499-2511, 2003.
-
(2003)
Curr Pharm des
, vol.9
, pp. 2499-2511
-
-
Alam, J.1
Deharo, D.2
Redding, K.M.3
Re, R.N.4
Cook, J.L.5
-
2
-
-
0027243681
-
Erythroid transcription factor NF-E2 is a hematopoietic-specific basic-leucine zipper protein
-
Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, and Orkin SH. Erythroid transcription factor NF-E2 is a hematopoietic-specific basic-leucine zipper protein. Nature 362: 722-728, 1993.
-
(1993)
Nature
, vol.362
, pp. 722-728
-
-
Andrews, N.C.1
Erdjument-Bromage, H.2
Davidson, M.B.3
Tempst, P.4
Orkin, S.H.5
-
3
-
-
0027145162
-
The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene
-
Andrews NC, Kotkow K J, Ney PA, Erdjument-Bromage H, Tempst P, and Orkin SH. The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene. Proc Natl Acad Sci USA 90: 11488-11492, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11488-11492
-
-
Andrews, N.C.1
Kotkow, K.J.2
Ney, P.A.3
Erdjument-Bromage, H.4
Tempst, P.5
Orkin, S.H.6
-
4
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expres-sion
-
Bloom DA and Jaiswal AK. Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expres-sion. J Biol Chem 278: 44675-44682, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
5
-
-
11844253848
-
Protection from mitochondrial complex II in-hibition in vitro and in vivo by Nrf2-mediated transcription
-
Calkins MJ, Jakel RJ, Johnson DA, Chan K, Kan YW, and Johnson JA. Protection from mitochondrial complex II in-hibition in vitro and in vivo by Nrf2-mediated transcription. Proc Natl Acad Sci USA 102: 244-249, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 244-249
-
-
Calkins, M.J.1
Jakel, R.J.2
Johnson, D.A.3
Chan, K.4
Kan, Y.W.5
Johnson, J.A.6
-
6
-
-
0037101768
-
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and in-ducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3, and Gstm4 genes in the livers of male and female mice
-
Chanas SA, Jiang Q, McMahon M, McWalter GK, McLellan LI, Elcombe CR, Henderson CJ, Wolf CR, Moffat GJ, Itoh K, Yamamoto M, and Hayes JD. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and in-ducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3, and Gstm4 genes in the livers of male and female mice. Biochem J 365: 405-416, 2002.
-
(2002)
Biochem J
, vol.365
, pp. 405-416
-
-
Chanas, S.A.1
Jiang, Q.2
McMahon, M.3
McWalter, G.K.4
McLellan, L.I.5
Elcombe, C.R.6
Henderson, C.J.7
Wolf, C.R.8
Moffat, G.J.9
Itoh, K.10
Yamamoto, M.11
Hayes, J.D.12
-
7
-
-
0027360226
-
Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast
-
Chan JY, Han XL, and Kan YW. Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci USA 90: 11371-11375, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11371-11375
-
-
Chan, J.Y.1
Han, X.L.2
Kan, Y.W.3
-
8
-
-
13044304201
-
Nrf2 is essential for protection against acute pulmonary injury in mice
-
Chan K and Kan YW. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc Natl Acad Sci USA 96: 12731-12736, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12731-12736
-
-
Chan, K.1
Kan, Y.W.2
-
9
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth and development
-
Chan K, Lu R, Chang JC, and Kan YW. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth and development. Proc Natl Acad Sci USA 93: 13943-13948, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
10
-
-
0036007313
-
Role of NRF2 in pro-tection against hyperoxic lung injury in mice
-
Cho HY, Jedlicka AE, Reddy SP, Kensler TW, Yamamoto M, Zhang LY, and Kleeberger SR. Role of NRF2 in pro-tection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26: 175-178, 2002.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 175-178
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Reddy, S.P.3
Kensler, T.W.4
Yamamoto, M.5
Zhang, L.Y.6
Kleeberger, S.R.7
-
11
-
-
58049088157
-
Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism in-volving an antioxidant response element
-
Chowdhury I, Mo Y, Gao L, Kazi A, Fisher AB, and Fein-stein SI. Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism in-volving an antioxidant response element. Free Radic Biol Med 46: 146-153, 2009.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 146-153
-
-
Chowdhury, I.1
Mo, Y.2
Gao, L.3
Kazi, A.4
Fisher, A.B.5
Fein-Stein, S.I.6
-
12
-
-
30344448851
-
"Phase i and Phase II" drug metabolism: Terminology that we should phase out?
-
David JP, Peter GF, and Miners JO. "Phase I and Phase II" drug metabolism: Terminology that we should phase out? Drug Metab Rev 37: 575-580, 2005.
-
(2005)
Drug Metab Rev
, vol.37
, pp. 575-580
-
-
David, J.P.1
Peter, G.F.2
Miners, J.O.3
-
13
-
-
0032086074
-
The detoxification enzyme system
-
DeAnn JL. The detoxification enzyme system. Alternat Med Rev 3: 187-198, 1998.
-
(1998)
Alternat Med Rev
, vol.3
, pp. 187-198
-
-
Deann, J.L.1
-
14
-
-
0035963293
-
Functional character-ization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: Quinone oxidoreductase1 gene
-
Dhakshinamoorthy S and Jaiswal AK. Functional character-ization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: quinone oxidoreductase1 gene. Oncogene 20: 3906-3917,2001.
-
(2001)
Oncogene
, vol.20
, pp. 3906-3917
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
15
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that pro-tect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, and Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that pro-tect against carcinogens and oxidants. Proc Natl Acad Sci USA 99: 11908-11913, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
17
-
-
33644662839
-
Heme oxygenase-1 gene enhancer manifests silencing activity in a chromatin environment prior to oxidative stress
-
Dohi Y, Alam J, Yoshizumi M, Sun J, and Igarashi K. Heme oxygenase-1 gene enhancer manifests silencing activity in a chromatin environment prior to oxidative stress. Antioxid Redox Signal 8: 60-67, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 60-67
-
-
Dohi, Y.1
Alam, J.2
Yoshizumi, M.3
Sun, J.4
Igarashi, K.5
-
18
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T, O'Connor T, Harada T, and Yamamoto M. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci 59: 169-177, 2001.
-
(2001)
Toxicol Sci
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
Harada, T.7
Yamamoto, M.8
-
19
-
-
0037163092
-
Iden-tification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence
-
Erickson AM, Nevarea Z, Gipp JJ, and Mulcahy RT. Iden-tification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence. J Biol Chem 277: 30730-30737, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 30730-30737
-
-
Erickson, A.M.1
Nevarea, Z.2
Gipp, J.J.3
Mulcahy, R.T.4
-
20
-
-
0025145723
-
Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element
-
Friling RS, Bensimon S, and Daniel V. Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element. Proc Natl Acad Sci USA 87: 6258-6262, 1990.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6258-6262
-
-
Friling, R.S.1
Bensimon, S.2
Daniel, V.3
-
21
-
-
0033000906
-
Inducible cyclooxygenase may have anti-inflammatory properties
-
Gilroy DW, Colville-Nash PR, Willis D, Chivers J, Paul-Clark MJ, and Willoughby DA. Inducible cyclooxygenase may have anti-inflammatory properties. Nat Med 5: 698-701, 1999.
-
(1999)
Nat Med
, vol.5
, pp. 698-701
-
-
Gilroy, D.W.1
Colville-Nash, P.R.2
Willis, D.3
Chivers, J.4
Paul-Clark, M.J.5
Willoughby, D.A.6
-
22
-
-
0036090689
-
12,14-prostaglandin J2 is mediated by the stress re-sponse elements and transcription factor Nrf2
-
12,14- prostaglandin J2 is mediated by the stress re-sponse elements and transcription factor Nrf2. Antioxid Redox Signal 4: 249-257, 2002.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 249-257
-
-
Gong, P.1
Stewart, D.2
Hu, B.3
Li, N.4
Cook, J.5
Nel, A.6
Alam, J.7
-
23
-
-
63549121490
-
NRF2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer
-
Hayes JD and McMahon M. NRF2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer. Trends Biochem Sci 34: 176-188, 2009.
-
(2009)
Trends Biochem Sci
, vol.34
, pp. 176-188
-
-
Hayes, J.D.1
McMahon, M.2
-
24
-
-
0033956744
-
The Nrf2 tran-scription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their in-duction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
-
Hayes JD, Chanas SA, Henderson CJ, McMahon M, Sun C, Moffat GJ, Wolf CR, and Yamamoto M. The Nrf2 tran-scription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their in-duction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin. Biochem Soc Trans 28: 33-41, 2000.
-
(2000)
Biochem Soc Trans
, vol.28
, pp. 33-41
-
-
Hayes, J.D.1
Chanas, S.A.2
Henderson, C.J.3
McMahon, M.4
Sun, C.5
Moffat, G.J.6
Wolf, C.R.7
Yamamoto, M.8
-
26
-
-
22844450096
-
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
-
Hosoya T, Maruyama A, Kang MI, Kawatani Y, Shibata T, Uchida K, Warabi E, Noguchi N, Itoh K, and Yamamoto M. Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. J Biol Chem 280: 27244-27250, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 27244-27250
-
-
Hosoya, T.1
Maruyama, A.2
Kang, M.I.3
Kawatani, Y.4
Shibata, T.5
Uchida, K.6
Warabi, E.7
Noguchi, N.8
Itoh, K.9
Yamamoto, M.10
-
27
-
-
34447326718
-
Vacuolar leukoence-phalopathy with widespread astrogliosis in mice lack-ing transcription factor Nrf2
-
Hubbs AF, Benkovic SA, Miller DB, O'Callaghan JP, Battelli L, Schwegler-Berry D, and Ma Q. Vacuolar leukoence-phalopathy with widespread astrogliosis in mice lack-ing transcription factor Nrf2. Am J Pathol 170: 2068-2076, 2007.
-
(2007)
Am J Pathol
, vol.170
, pp. 2068-2076
-
-
Hubbs, A.F.1
Benkovic, S.A.2
Miller, D.B.3
O'Callaghan, J.P.4
Battelli, L.5
Schwegler-Berry, D.6
Ma, Q.7
-
28
-
-
33644643191
-
The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid dif-ferentiation
-
Igarashi K and Sun J. The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid dif-ferentiation. Antioxid Redox Signal 8: 107-118, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 107-118
-
-
Igarashi, K.1
Sun, J.2
-
29
-
-
0028118492
-
Regulation of transcription by dimer-ization of erythroid factor NF-E2 p45 with small Maf pro-teins
-
Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, and Yamamoto, M. Regulation of transcription by dimer-ization of erythroid factor NF-E2 p45 with small Maf pro-teins. Nature 367: 568-572, 1994.
-
(1994)
Nature
, vol.367
, pp. 568-572
-
-
Igarashi, K.1
Kataoka, K.2
Itoh, K.3
Hayashi, N.4
Nishizawa, M.5
Yamamoto, M.6
-
30
-
-
4644328941
-
Nrf2 is essential for the chemopreventive efficacy of oltipraz against uri-nary bladder carcinogenesis
-
Iida K, Itoh K, Kumagai Y, Oyasu R, Hattori K, Kawai K, Shimazui T, Akaza H, and Yamamoto M. Nrf2 is essential for the chemopreventive efficacy of oltipraz against uri-nary bladder carcinogenesis. Cancer Res 64: 6424-6431, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 6424-6431
-
-
Iida, K.1
Itoh, K.2
Kumagai, Y.3
Oyasu, R.4
Hattori, K.5
Kawai, K.6
Shimazui, T.7
Akaza, H.8
Yamamoto, M.9
-
31
-
-
29244473882
-
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema
-
Iizuka T, Ishii Y, Itoh K, Kiwamoto T, Kimura T, Matsuno Y, Morishima Y, Hegab AE, Homma S, Nomura A, Sakamoto T, Shimura M, Yoshida A, Yamamoto M, and Sekizawa K. Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema. Genes Cells 10: 1113-1125, 2005.
-
(2005)
Genes Cells
, vol.10
, pp. 1113-1125
-
-
Iizuka, T.1
Ishii, Y.2
Itoh, K.3
Kiwamoto, T.4
Kimura, T.5
Matsuno, Y.6
Morishima, Y.7
Hegab, A.E.8
Homma, S.9
Nomura, A.10
Sakamoto, T.11
Shimura, M.12
Yoshida, A.13
Yamamoto, M.14
Sekizawa, K.15
-
32
-
-
0029945755
-
The heme-responsive element of the mouse heme oxygenase-1 gene is an extended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors
-
DOI 10.1006/bbrc.1996.0637
-
Inamdar NM, Ahn YI, and Alam J. The heme-responsive element of the mouse heme oxygenase-1 gene is an ex-tended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors. Bio-chem Biophys Res Commun 221: 570-576, 1996. (Pubitemid 26153905)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.221
, Issue.3
, pp. 570-576
-
-
Inamdar, N.M.1
Ahn, Y.I.2
Alam, J.3
-
33
-
-
0032843695
-
Oxidative stress-in-ducible proteins in macrophages
-
Ishii T, Itoh K, Sato H, and Bannai S. Oxidative stress-in-ducible proteins in macrophages. Free Radic Res 31: 351-355, 1999.
-
(1999)
Free Radic Res
, vol.31
, pp. 351-355
-
-
Ishii, T.1
Itoh, K.2
Sato, H.3
Bannai, S.4
-
34
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S, and Yamamoto M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275: 16023-16029, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
Bannai, S.7
Yamamoto, M.8
-
35
-
-
27744450995
-
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema
-
Ishii Y, Itoh K, Morishima Y, Kimura T, Kiwamoto T, Iizuka T, Hegab AE, Hosoya T, Nomura A, Sakamoto T, Yamamoto M, and Sekizawa K. Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema. J Immunol 175: 6968-6975, 2005.
-
(2005)
J Immunol
, vol.175
, pp. 6968-6975
-
-
Ishii, Y.1
Itoh, K.2
Morishima, Y.3
Kimura, T.4
Kiwamoto, T.5
Iizuka, T.6
Hegab, A.E.7
Hosoya, T.8
Nomura, A.9
Sakamoto, T.10
Yamamoto, M.11
Sekizawa, K.12
-
36
-
-
33646675588
-
Protective mechanism against oxidative stress by Keap1/Nrf2 pathway
-
Itoh K. Protective mechanism against oxidative stress by Keap1/Nrf2 pathway. Seikagaku 78: 79-92, 2006.
-
(2006)
Seikagaku
, vol.78
, pp. 79-92
-
-
Itoh, K.1
-
37
-
-
29344450927
-
Regulatory role of the COX-2 pathway in the Nrf2-mediated anti-inflammatory response
-
Itoh K and Yamamoto M. Regulatory role of the COX-2 pathway in the Nrf2-mediated anti-inflammatory response. J Clin Biochem Nutri 37: 9-18, 2005.
-
(2005)
J Clin Biochem Nutri
, vol.37
, pp. 9-18
-
-
Itoh, K.1
Yamamoto, M.2
-
38
-
-
0031577292
-
An Nrf2/small Maf heterodimer medi-ates the induction of phase II detoxifying enzyme genes through antioxidant responsive elements
-
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, and Nabeshima Y. An Nrf2/small Maf heterodimer medi-ates the induction of phase II detoxifying enzyme genes through antioxidant responsive elements. Biochem Biophys Res Commun 236: 313-322, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
39
-
-
0029043995
-
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor hetero-dimerizing with the small maf family proteins
-
Itoh K, Igarashi K, Hayashi N, Nishizawa M, and Yama-moto M. Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor hetero-dimerizing with the small maf family proteins. Mol Cell Biol 15: 4184-4193, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4184-4193
-
-
Itoh, K.1
Igarashi, K.2
Hayashi, N.3
Nishizawa, M.4
Yama-Moto, M.5
-
40
-
-
10744230015
-
2
-
2. Mol Cell Biol 24: 36-45, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 36-45
-
-
Itoh, K.1
Mochizuki, M.2
Ishii, Y.3
Ishii, T.4
Shibata, T.5
Kawamoto, Y.6
Kelly, V.7
Sekizawa, K.8
Uchida, K.9
Yamamoto, M.10
-
41
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive element by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, and Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive element by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13: 76-86, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
42
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electro-philes
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, O'Connor T, and Yamamoto M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electro-philes. Genes Cells 8: 379-391, 2003.
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
O'Connor, T.5
Yamamoto, M.6
-
43
-
-
0025611278
-
The enzyme of detoxification
-
Jakoby WB and Ziegler DM. The enzyme of detoxification. J Biol Chem 265: 20715-20718, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 20715-20718
-
-
Jakoby, W.B.1
Ziegler, D.M.2
-
44
-
-
1242274394
-
Scaffolding of Keap1 to the actin cytoskele-ton controls the function of Nrf2 as key regulator of cyto-protective phase 2 genes
-
Kang MI, Kobayashi A, Wakabayashi N, Kim SG, and Yamamoto M. Scaffolding of Keap1 to the actin cytoskele-ton controls the function of Nrf2 as key regulator of cyto-protective phase 2 genes. Proc Natl Acad Sci USA 101: 2046-2051, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2046-2051
-
-
Kang, M.I.1
Kobayashi, A.2
Wakabayashi, N.3
Kim, S.G.4
Yamamoto, M.5
-
45
-
-
0027954409
-
Maf nuclear on-coprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun
-
Kataoka K, Noda M, and Nishizawa M. Maf nuclear on-coprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol Cell Biol 14: 700-712, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 700-712
-
-
Kataoka, K.1
Noda, M.2
Nishizawa, M.3
-
46
-
-
0028986047
-
Small Maf proteins het-erodimerize with Fos and may act as competitive repres-sors of the NF-E2 transcription factor
-
Kataoka K, Igarashi K, Itoh K, Fujiwara KT, Noda M, Yamamoto M, and Nishizawa M. Small Maf proteins het-erodimerize with Fos and may act as competitive repres-sors of the NF-E2 transcription factor. Mol Cell Biol 15: 2180-2190, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2180-2190
-
-
Kataoka, K.1
Igarashi, K.2
Itoh, K.3
Fujiwara, K.T.4
Noda, M.5
Yamamoto, M.6
Nishizawa, M.7
-
47
-
-
9944255781
-
Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome
-
Katoh Y, Iida K, Kang MI, Kobayashi A, Mizukami M, Tong KI, McMahon M, Hayes JD, Itoh K, and Yamamoto M. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome. Arch Biochem Biophys 433: 342-350, 2005.
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 342-350
-
-
Katoh, Y.1
Iida, K.2
Kang, M.I.3
Kobayashi, A.4
Mizukami, M.5
Tong, K.I.6
McMahon, M.7
Hayes, J.D.8
Itoh, K.9
Yamamoto, M.10
-
48
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, and Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6: 857-868, 2001.
-
(2001)
Genes Cells
, vol.6
, pp. 857-868
-
-
Katoh, Y.1
Itoh, K.2
Yoshida, E.3
Miyagishi, M.4
Fukamizu, A.5
Yamamoto, M.6
-
49
-
-
0034646646
-
2-induced expression of glutathione S-transferases
-
2-induced expression of glutathione S-transferases. J Biol Chem 275: 11291-11299, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 11291-11299
-
-
Kawamoto, Y.1
Nakamura, Y.2
Naito, Y.3
Torii, Y.4
Kumagai, T.5
Osawa, T.6
Ohigashi, H.7
Satoh, K.8
Imagawa, M.9
Uchida, K.10
-
50
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler TW, Wakabayashi N, and Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 47: 89-116, 2007.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
51
-
-
0028053782
-
A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins
-
Kerppola TK and Curran T. A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins. Oncogene 9: 3149-3158, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3149-3158
-
-
Kerppola, T.K.1
Curran, T.2
-
52
-
-
33846264538
-
Nrf2-deficient mice have an increased suscepti-bility to dextran sulfate sodium-induced colitis
-
Khor TO, Huang MT, Kwon KH, Chan JY, Reddy BS, and Kong AN. Nrf2-deficient mice have an increased suscepti-bility to dextran sulfate sodium-induced colitis. Cancer Res 66: 11580-11584, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 11580-11584
-
-
Khor, T.O.1
Huang, M.T.2
Kwon, K.H.3
Chan, J.Y.4
Reddy, B.S.5
Kong, A.N.6
-
53
-
-
36349030396
-
Molecular basis distin-guishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer
-
Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M. Molecular basis distin-guishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer. J Biol Chem 282: 33681-33690, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 33681-33690
-
-
Kimura, M.1
Yamamoto, T.2
Zhang, J.3
Itoh, K.4
Kyo, M.5
Kamiya, T.6
Aburatani, H.7
Katsuoka, F.8
Kurokawa, H.9
Tanaka, T.10
Motohashi, H.11
Yamamoto, M.12
-
54
-
-
0033525730
-
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3
-
Kobayashi A, Ito E, Toki T, Kogame K, Takahashi S, Igar-ashi K, Hayashi N, and Yamamoto M. Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J Biol Chem 274: 6443-6452, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 6443-6452
-
-
Kobayashi, A.1
Ito, E.2
Toki, T.3
Kogame, K.4
Takahashi, S.5
Igar-Ashi, K.6
Hayashi, N.7
Yamamoto, M.8
-
55
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, and Yamamoto M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 24: 7130-7139, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
56
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
Kobayashi M, Itoh K, Suzuki T, Osanai H, Nishikawa K, Katoh Y, Takagi Y, and Yamamoto M. Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7: 807-820, 2002.
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
Takagi, Y.7
Yamamoto, M.8
-
57
-
-
71949088553
-
Structural basis of alternative DNA recognition by Maf transcription fac-tors
-
Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, and Tanaka T. Structural basis of alternative DNA recognition by Maf transcription fac-tors. Mol Cell Biol 29: 6232-6244, 2009.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6232-6244
-
-
Kurokawa, H.1
Motohashi, H.2
Sueno, S.3
Kimura, M.4
Takagawa, H.5
Kanno, Y.6
Yamamoto, M.7
Tanaka, T.8
-
58
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway
-
Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yama-moto M, and Kensler TW. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. J Biol Chem 278: 8135-8145, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yama-Moto, M.5
Kensler, T.W.6
-
59
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide micro-array analysis
-
Lee JM, Calkins MJ, Chan K, Kan YW, and Johnson JA. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide micro-array analysis. J Biol Chem 278: 12029-12038, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 12029-12038
-
-
Lee, J.M.1
Calkins, M.J.2
Chan, K.3
Kan, Y.W.4
Johnson, J.A.5
-
60
-
-
0026755187
-
Regulation of human NAD(P)H:qui-none oxidoreductase gene. Role of AP1 binding site con-tained within human antioxidant response element
-
Li Y and Jaiswal AK. Regulation of human NAD(P)H:qui-none oxidoreductase gene. Role of AP1 binding site con-tained within human antioxidant response element. J Biol Chem 267: 15097-5104, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 15097-5104
-
-
Li, Y.1
Jaiswal, A.K.2
-
61
-
-
70249138697
-
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: Demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 path-way, controls cytoprotection against electrophiles as well as redox-cycling compounds
-
MacLeod AK, McMahon M, Plummer SM, Higgins LG, Penning TM, Igarashi K, and Hayes JD. Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: Demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 path-way, controls cytoprotection against electrophiles as well as redox-cycling compounds. Carcinogenesis 30: 1571-1580, 2009.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1571-1580
-
-
MacLeod, A.K.1
McMahon, M.2
Plummer, S.M.3
Higgins, L.G.4
Penning, T.M.5
Igarashi, K.6
Hayes, J.D.7
-
62
-
-
33744729373
-
Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and im-paired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
-
Ma Q, Battelli L, and Hubbs AF. Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and im-paired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2. Am J Pathol 168: 1960-1974, 2006.
-
(2006)
Am J Pathol
, vol.168
, pp. 1960-1974
-
-
Ma, Q.1
Battelli, L.2
Hubbs, A.F.3
-
63
-
-
48749091560
-
Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant re-sponse elements
-
Maruyama A, Tsukamoto S, Nishikawa K, Yoshida A, Harada N, Motojima K, Ishii T, Nakane A, Yamamoto M, and Itoh K. Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant re-sponse elements. Arch Biochem Biophys 477: 139-145, 2008.
-
(2008)
Arch Biochem Biophys
, vol.477
, pp. 139-145
-
-
Maruyama, A.1
Tsukamoto, S.2
Nishikawa, K.3
Yoshida, A.4
Harada, N.5
Motojima, K.6
Ishii, T.7
Nakane, A.8
Yamamoto, M.9
Itoh, K.10
-
64
-
-
0035870298
-
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and gluta-thione biosynthetic enzymes
-
McMahon M, Itoh K, Yamamoto M, Chanas SA, Henderson CJ, McLellan LI, Wolf CR, Cavin C, and Hayes JD. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and gluta-thione biosynthetic enzymes. Cancer Res 61: 3299-3307, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 3299-3307
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Chanas, S.A.4
Henderson, C.J.5
McLellan, L.I.6
Wolf, C.R.7
Cavin, C.8
Hayes, J.D.9
-
65
-
-
3843104763
-
Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
-
McMahon M, Thomas N, Itoh K, Yamamoto M, and Hayes JD. Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron. J Biol Chem 279: 31556-31567, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 31556-31567
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
66
-
-
0000976220
-
Cis-and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deami-nase gene
-
Mignotte V, Eleouet JF, Raich N, and Romeo PH. Cis-and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deami-nase gene. Proc Natl Acad Sci USA 89: 6548-6552, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.89
, pp. 6548-6552
-
-
Mignotte, V.1
Eleouet, J.F.2
Raich, N.3
Romeo, P.H.4
-
67
-
-
0016721066
-
Metabolic activation and reactivity of chemical carcinogens
-
Miller JA and Miller EC Metabolic activation and reactivity of chemical carcinogens. Mutat Res 33: 25-26, 1975.
-
(1975)
Mutat Res
, vol.33
, pp. 25-26
-
-
Miller, J.A.1
Miller, E.C.2
-
68
-
-
21144456105
-
2 pathways in protection against acute lung injury
-
DOI 10.1164/rccm.200406-755OC
-
2 and Nrf2 path-ways in protection against acute lung injury. Am J Respir Crit Care Med 171: 1260-1266, 2005. (Pubitemid 40740733)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.11
, pp. 1260-1266
-
-
Mochizuki, M.1
Ishii, Y.2
Itoh, K.3
Iizuka, T.4
Morishima, Y.5
Kimura, T.6
Kiwamoto, T.7
Matsuno, Y.8
Hegab, A.E.9
Nomura, A.10
Sakamoto, T.11
Uchida, K.12
Yamamoto, M.13
Sekizawa, K.14
-
69
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
Moi P, Chan K, Asunis I, Cao A, and Kan YW. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 91: 9926-9930, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
70
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
Motohashi H and Yamamoto M. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol Med 10: 549-557, 2004.
-
(2004)
Trends Mol Med
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
71
-
-
0030791154
-
The world according to Maf
-
Motohashi H, Shavit JA, Igarashi K, Yamamoto M, and Engel JD. The world according to Maf. Nucleic Acids Res 25: 2953-2959, 1997.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2953-2959
-
-
Motohashi, H.1
Shavit, J.A.2
Igarashi, K.3
Yamamoto, M.4
Engel, J.D.5
-
72
-
-
0025274623
-
Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals
-
Nelson SD and Pearson PG. Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals. Annu Rev Pharmacol Toxicol 30: 169-195, 1990.
-
(1990)
Annu Rev Pharmacol Toxicol
, vol.30
, pp. 169-195
-
-
Nelson, S.D.1
Pearson, P.G.2
-
73
-
-
0025080566
-
Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein
-
Ney PA, Sorrentino BP, Lowrey CH, and Nienhuis AW. Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res 18: 6011-6017, 1990.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6011-6017
-
-
Ney, P.A.1
Sorrentino, B.P.2
Lowrey, C.H.3
Nienhuis, A.W.4
-
74
-
-
67649402187
-
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T, Nioi P, and Pickett CB. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284: 13291-13295, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
75
-
-
25444449520
-
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nu-cleocytoplasmic shuttling by Keap1
-
Nguyen T, Sherratt PJ, Nioi P, Yang CS, and Pickett CB. Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nu-cleocytoplasmic shuttling by Keap1. J Biol Chem 280: 32485-32492, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 32485-32492
-
-
Nguyen, T.1
Sherratt, P.J.2
Nioi, P.3
Yang, C.S.4
Pickett, C.B.5
-
76
-
-
28544450507
-
The carboxy-terminal Neh3 domain of Nrf2 is required for transcrip-tional activation
-
Nioi P, Nguyen T, Sherratt PJ, and Pickett CB. The carboxy-terminal Neh3 domain of Nrf2 is required for transcrip-tional activation. Mol Cell Biol 25: 10895-10906, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10895-10906
-
-
Nioi, P.1
Nguyen, T.2
Sherratt, P.J.3
Pickett, C.B.4
-
77
-
-
0344142025
-
V-maf a viral oncogene that encodes a "leucine zipper" motif
-
Nishizawa M, Kataoka K, Goto N, Fujiwara KT, and Kawai S. v-maf, a viral oncogene that encodes a "leucine zipper" motif. Proc Natl Acad Sci USA 86: 7711-7715, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7711-7715
-
-
Nishizawa, M.1
Kataoka, K.2
Goto, N.3
Fujiwara, K.T.4
Kawai, S.5
-
78
-
-
70449713440
-
Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems
-
Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, and Yamamoto M. Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems. Biochem Biophys Res Commun 389: 431-436, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 431-436
-
-
Okada, K.1
Shoda, J.2
Taguchi, K.3
Maher, J.M.4
Ishizaki, K.5
Inoue, Y.6
Ohtsuki, M.7
Goto, N.8
Sugimoto, H.9
Utsunomiya, H.10
Oda, K.11
Warabi, E.12
Ishii, T.13
Yamamoto, M.14
-
79
-
-
28144445947
-
Hepatocyte-specific dele-tion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
-
Okawa H, Motohashi H, Kobayashi A, Aburatani H, Kensler TW, and Yamamoto M. Hepatocyte-specific dele-tion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem Biophys Res Commun 339: 79-88, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 79-88
-
-
Okawa, H.1
Motohashi, H.2
Kobayashi, A.3
Aburatani, H.4
Kensler, T.W.5
Yamamoto, M.6
-
80
-
-
0029805130
-
Bach proteins belong to a novel family of BTB-basic leucine zipper tran-scription factors that interact with MafK and regulate transcription through the NF-E2 site
-
Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M, Yamamoto M, and Igarashi K. Bach proteins belong to a novel family of BTB-basic leucine zipper tran-scription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16: 6083-6095, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6083-6095
-
-
Oyake, T.1
Itoh, K.2
Motohashi, H.3
Hayashi, N.4
Hoshino, H.5
Nishizawa, M.6
Yamamoto, M.7
Igarashi, K.8
-
81
-
-
33344456501
-
Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer
-
Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, and Yamamoto M. Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell 21: 689-700, 2006.
-
(2006)
Mol Cell
, vol.21
, pp. 689-700
-
-
Padmanabhan, B.1
Tong, K.I.2
Ohta, T.3
Nakamura, Y.4
Scharlock, M.5
Ohtsuji, M.6
Kang, M.I.7
Kobayashi, A.8
Yokoyama, S.9
Yamamoto, M.10
-
82
-
-
0020534572
-
Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA
-
Pearson WR, Windle JJ, Morrow JF, Benson AM, and Ta-lalay P. Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. J Biol Chem 258: 2052-2062, 1983.
-
(1983)
J Biol Chem
, vol.258
, pp. 2052-2062
-
-
Pearson, W.R.1
Windle, J.J.2
Morrow, J.F.3
Benson, A.M.4
Talalay, P.5
-
83
-
-
0027394238
-
Che-mical and molecular regulation of enzymes that detoxify carcinogens
-
Prestera T, Holtzclaw WD, Zhang Y, and Talalay P. Che-mical and molecular regulation of enzymes that detoxify carcinogens. Proc Natl Acad Sci USA 90: 2965-2969, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2965-2969
-
-
Prestera, T.1
Holtzclaw, W.D.2
Zhang, Y.3
Talalay, P.4
-
84
-
-
0029411321
-
Parallel induction of heme oxygenase-1 and che-moprotective phase 2 enzymes by electrophiles and anti-oxidants: Regulation by upstream antioxidant-responsive elements (ARE)
-
Prestera T, Talalay P, Alam J, Ahn Y, Lee PJ, and Choi AMK. Parallel induction of heme oxygenase-1 and che-moprotective phase 2 enzymes by electrophiles and anti-oxidants: Regulation by upstream antioxidant-responsive elements (ARE). Mol Med 1: 827-837, 1995.
-
(1995)
Mol Med
, vol.1
, pp. 827-837
-
-
Prestera, T.1
Talalay, P.2
Alam, J.3
Ahn, Y.4
Lee, P.J.5
Choi, A.M.K.6
-
86
-
-
0022361083
-
Specificity of induction of cancer protective enzymes by analogues of tert-butyl-4-hydroxyanisole (BHA)
-
Prochaska HJ, Bregman HS, De Long MJ, and Talalay P. Specificity of induction of cancer protective enzymes by analogues of tert-butyl-4- hydroxyanisole (BHA). Biochem Pharmacol 34: 3909-3914, 1985.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 3909-3914
-
-
Prochaska, H.J.1
Bregman, H.S.2
De Long, M.J.3
Talalay, P.4
-
87
-
-
0001143581
-
On the mecha-nisms of induction of cancer-protective enzymes: A unify-ing proposal
-
Prochaska HJ, De Long MJ, and Talalay P. On the mecha-nisms of induction of cancer-protective enzymes: A unify-ing proposal. Proc Natl Acad Sci USA 82: 8232-8236, 1985.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 8232-8236
-
-
Prochaska, H.J.1
De Long, M.J.2
Talalay, P.3
-
88
-
-
0023777834
-
Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver
-
Prochaska HJ and Talalay P. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res 48: 4776-4782, 1988.
-
(1988)
Cancer Res
, vol.48
, pp. 4776-4782
-
-
Prochaska, H.J.1
Talalay, P.2
-
89
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme in-ducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, and Kensler TW. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme in-ducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98: 3410-3415, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
90
-
-
61349117533
-
Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that de-toxify electrophiles more than those that detoxify reactive oxygen species
-
Reisman SA, Yeager RL, Yamamoto M, and Klaassen CD. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that de-toxify electrophiles more than those that detoxify reactive oxygen species. Toxicol Sci 108: 35-47, 2009.
-
(2009)
Toxicol Sci
, vol.108
, pp. 35-47
-
-
Reisman, S.A.1
Yeager, R.L.2
Yamamoto, M.3
Klaassen, C.D.4
-
91
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, and Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391: 79-82, 1998.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
92
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase
-
Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, Karin M, and Santoro MG. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 403: 103-108, 2000.
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
Santoro, M.G.7
-
93
-
-
0024997241
-
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Char-acterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
-
Rushmore TH and Pickett CB. Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Char-acterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants. J Biol Chem 265: 14648-14653, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 14648-14653
-
-
Rushmore, T.H.1
Pickett, C.B.2
-
95
-
-
0037160092
-
Electrophile response element-mediated induc-tion of the cystine/glutamate exchange transporter gene expression
-
Sasaki H, Sato H, Kuriyama-Matsumura K, Sato K, Mae-bara K, Wang H, Tamba M, Itoh K, Yamamoto M, and Bannai S. Electrophile response element-mediated induc-tion of the cystine/glutamate exchange transporter gene expression. J Biol Chem 277: 44765-44771, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 44765-44771
-
-
Sasaki, H.1
Sato, H.2
Kuriyama-Matsumura, K.3
Sato, K.4
Mae-Bara, K.5
Wang, H.6
Tamba, M.7
Itoh, K.8
Yamamoto, M.9
Bannai, S.10
-
96
-
-
0037996661
-
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
-
Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, and Murphy TH. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 23: 3394-3406, 2003.
-
(2003)
J Neurosci
, vol.23
, pp. 3394-3406
-
-
Shih, A.Y.1
Johnson, D.A.2
Wong, G.3
Kraft, A.D.4
Jiang, L.5
Erb, H.6
Johnson, J.A.7
Murphy, T.H.8
-
97
-
-
20744440945
-
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo
-
Shih AY, Imbeault S, Barakauskas V, Erb H, Jiang L, Li P, and Murphy TH. Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. J Biol Chem 280: 22925-22936, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 22925-22936
-
-
Shih, A.Y.1
Imbeault, S.2
Barakauskas, V.3
Erb, H.4
Jiang, L.5
Li, P.6
Murphy, T.H.7
-
98
-
-
24344509192
-
Extracellular acidification enhances DNA binding activity of MafG-FosB heterodimer
-
Shimokawa N, Kumaki I, Qiu CH, Ohmiya Y, Takayama K, and Koibuchi N. Extracellular acidification enhances DNA binding activity of MafG-FosB heterodimer. J Cell Physiol 205: 77-85, 2005.
-
(2005)
J Cell Physiol
, vol.205
, pp. 77-85
-
-
Shimokawa, N.1
Kumaki, I.2
Qiu, C.H.3
Ohmiya, Y.4
Takayama, K.5
Koibuchi, N.6
-
99
-
-
0031474716
-
Ah receptor, a novel ligand-activated transcription factor
-
Sogawa K and Fujii-Kuriyama Y. Ah receptor, a novel ligand-activated transcription factor. J Biochem 122: 1075-1079, 1997.
-
(1997)
J Biochem
, vol.122
, pp. 1075-1079
-
-
Sogawa, K.1
Fujii-Kuriyama, Y.2
-
100
-
-
34548772935
-
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2
-
Sun Z, Zhang S, Chan JY, and Zhang DD. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Mol Cell Biol 27: 6334-6349, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6334-6349
-
-
Sun, Z.1
Zhang, S.2
Chan, J.Y.3
Zhang, D.D.4
-
101
-
-
2942689213
-
MafT a new member of the small Maf protein family in zebrafish
-
Takagi Y, Kobayashi M, Li L, Suzuki T, Nishikawa K, and Yamamoto M. MafT, a new member of the small Maf protein family in zebrafish Biochem Biophys Res Commun 320: 62-69, 2004.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 62-69
-
-
Takagi, Y.1
Kobayashi, M.2
Li, L.3
Suzuki, T.4
Nishikawa, K.5
Yamamoto, M.6
-
102
-
-
0026576256
-
Structure of the human ferrochelatase gene. Exon/intron gene organization and location of the gene to chromosome 18
-
Taketani S, Inazawa J, Nakahashi Y, Abe T, and Tokunaga R. Structure of the human ferrochelatase gene. Exon/intron gene organization and location of the gene to chromosome 18. Eur J Biochem 205: 217-222, 1992.
-
(1992)
Eur J Biochem
, vol.205
, pp. 217-222
-
-
Taketani, S.1
Inazawa, J.2
Nakahashi, Y.3
Abe, T.4
Tokunaga, R.5
-
103
-
-
0034490852
-
Chemoprotection against cancer by induction of phase 2 enzymes
-
Talalay P. Chemoprotection against cancer by induction of phase 2 enzymes. Biofactors 12: 5-11, 2000.
-
(2000)
Biofactors
, vol.12
, pp. 5-11
-
-
Talalay, P.1
-
104
-
-
0024781837
-
Mechanisms of induction of enzymes that pro-tect against chemical carcinogenesis
-
Talalay P. Mechanisms of induction of enzymes that pro-tect against chemical carcinogenesis. Adv Enzyme Regul 28: 237-250, 1989.
-
(1989)
Adv Enzyme Regul
, vol.28
, pp. 237-250
-
-
Talalay, P.1
-
105
-
-
33645530745
-
Nrf2 is a critical regulator of the innate immune response and sur-vival during experimental sepsis
-
Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, and Biswal S. Nrf2 is a critical regulator of the innate immune response and sur-vival during experimental sepsis. J Clin Invest 116: 984-995, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
Reddy, S.P.4
Yamamoto, M.5
Kensler, T.W.6
Biswal, S.7
-
106
-
-
33344463325
-
Keap1 recruits Neh2 through binding to ETGE and DLG motifs: Characterization of the two-site molecular recognition model
-
Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, and Yamamoto M. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: Characterization of the two-site molecular recognition model. Mol Cell Biol 26: 2887-2900, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
107
-
-
33750613056
-
Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism
-
Tong KI, Kobayashi A, Katsuoka F, and Yamamoto M. Two-site substrate recognition model for the Keap1-Nrf2 system: A hinge and latch mechanism. Biol Chem 387:1311-1320, 2006.
-
(2006)
Biol Chem
, vol.387
, pp. 1311-1320
-
-
Tong, K.I.1
Kobayashi, A.2
Katsuoka, F.3
Yamamoto, M.4
-
108
-
-
46449115525
-
Peroxynitrite de-toxification and its biologic implications
-
Trujillo M, Ferrer-Sueta G, and Radi R. Peroxynitrite de-toxification and its biologic implications. Antioxid Redox Signal 10: 1607-1620, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1607-1620
-
-
Trujillo, M.1
Ferrer-Sueta, G.2
Radi, R.3
-
109
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:qui-none oxidoreductase1 gene
-
Venugopal R and Jaiswal AK. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:qui-none oxidoreductase1 gene. Proc Natl Acad Sci USA 93: 14960-14965, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
110
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, Harada T, Engel JD, and Yamamoto M. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet 35: 238-245, 2003.
-
(2003)
Nat Genet
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
111
-
-
0034698045
-
A conserved tran-scription motif suggesting functional parallels between Caenorhabditis elegans SKN-1 and Cap'n'Collar-related basic leucine zipper proteins
-
Walker AK, See R, Batchelder C, Kophengnavong T, Gronniger JT, Shi Y, and Blackwell TK. A conserved tran-scription motif suggesting functional parallels between Caenorhabditis elegans SKN-1 and Cap'n'Collar-related basic leucine zipper proteins. J Biol Chem 275: 22166-22171, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 22166-22171
-
-
Walker, A.K.1
See, R.2
Batchelder, C.3
Kophengnavong, T.4
Gronniger, J.T.5
Shi, Y.6
Blackwell, T.K.7
-
112
-
-
0031000208
-
Functional antioxidant re-sponsive elements
-
Wasserman WW and Fahl WE. Functional antioxidant re-sponsive elements. Proc Natl Acad Sci USA 94: 5361-5366, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5361-5366
-
-
Wasserman, W.W.1
Fahl, W.E.2
-
113
-
-
0023178836
-
Induction of cystine transport activity in mouse peritoneal macrophages
-
Watanabe H and Bannai S. Induction of cystine transport activity in mouse peritoneal macrophages. J Exp Med 165: 628-640, 1987.
-
(1987)
J Exp Med
, vol.165
, pp. 628-640
-
-
Watanabe, H.1
Bannai, S.2
-
114
-
-
0017917866
-
Inhibitors of chemical carcinogenesis
-
Wattenberg, LW. Inhibitors of chemical carcinogenesis. Adv Cancer Res 26: 197-226, 1978.
-
(1978)
Adv Cancer Res
, vol.26
, pp. 197-226
-
-
Wattenberg, L.W.1
-
115
-
-
0030045835
-
Heme oxygenase: A novel target for the modulation of the inflammatory response
-
Willis D, Moore AR, Frederick R, and Willoughby DA. Heme oxygenase: A novel target for the modulation of the inflammatory response. Nat Med 2: 87-90, 1996.
-
(1996)
Nat Med
, vol.2
, pp. 87-90
-
-
Willis, D.1
Moore, A.R.2
Frederick, R.3
Willoughby, D.A.4
-
116
-
-
4344594011
-
Nrf2 defi-ciency causes tooth decolourization due to iron transport disorder in enamel organ
-
Yanagawa T, Itoh K, Uwayama J, Shibata Y, Yamaguchi A, Sano T, Ishii T, Yoshida H, and Yamamoto M. Nrf2 defi-ciency causes tooth decolourization due to iron transport disorder in enamel organ. Genes Cells 9: 641-651, 2004.
-
(2004)
Genes Cells
, vol.9
, pp. 641-651
-
-
Yanagawa, T.1
Itoh, K.2
Uwayama, J.3
Shibata, Y.4
Yamaguchi, A.5
Sano, T.6
Ishii, T.7
Yoshida, H.8
Yamamoto, M.9
-
117
-
-
34249051418
-
Large Maf transcription factors: Cousins of AP-1 proteins and important regulators of cel-lular differentiation
-
Yang Y and Cvekl A. Large Maf transcription factors: Cousins of AP-1 proteins and important regulators of cel-lular differentiation. Einstein J Biol Med 23: 2-11, 2007.
-
(2007)
Einstein J Biol Med
, vol.23
, pp. 2-11
-
-
Yang, Y.1
Cvekl, A.2
-
118
-
-
33646196955
-
Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells
-
Yeh CT and Yen GC. Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells. Carcinogenesis 27: 1008-1017, 2006.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1008-1017
-
-
Yeh, C.T.1
Yen, G.C.2
-
119
-
-
0034785941
-
Nrf2-deficient female mice develop lupus-like autoimmune nephritis
-
Yoh K, Itoh K, Enomoto A, Hirayama A, Yamaguchi N, Kobayashi M, Morito N, Koyama A, Yamamoto M, and Takahashi S. Nrf2-deficient female mice develop lupus-like autoimmune nephritis. Kidney Int 60: 1343-1353, 2001.
-
(2001)
Kidney Int
, vol.60
, pp. 1343-1353
-
-
Yoh, K.1
Itoh, K.2
Enomoto, A.3
Hirayama, A.4
Yamaguchi, N.5
Kobayashi, M.6
Morito, N.7
Koyama, A.8
Yamamoto, M.9
Takahashi, S.10
-
120
-
-
33644842869
-
Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites
-
Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Tallman MN, and Brouwer KL. Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites. Eur J Pharm Sci 27: 447-486, 2006.
-
(2006)
Eur J Pharm Sci
, vol.27
, pp. 447-486
-
-
Zamek-Gliszczynski, M.J.1
Hoffmaster, K.A.2
Nezasa, K.3
Tallman, M.N.4
Brouwer, K.L.5
-
121
-
-
34250743585
-
-
Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K and Yamamoto M. Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes. Bio-chem J 404: 459-466, 2007.
-
(2007)
Nrf2 Neh5 Domain Is Differentially Utilized in the Transactivation of Cytoprotective Genes. Bio-chem J
, vol.404
, pp. 459-466
-
-
Zhang, J.1
Hosoya, T.2
Maruyama, A.3
Nishikawa, K.4
Maher, J.M.5
Ohta, T.6
Motohashi, H.7
Fukamizu, A.8
Shibahara, S.9
Itoh, K.10
Yamamoto, M.11
-
122
-
-
33750308605
-
BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress
-
Zhang J, Ohta T, Maruyama A, Hosoya T, Nishikawa K, Maher JM, Shibahara S, Itoh K, and Yamamoto M. BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress. Mol Cell Biol 26: 7942-7952, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7942-7952
-
-
Zhang, J.1
Ohta, T.2
Maruyama, A.3
Hosoya, T.4
Nishikawa, K.5
Maher, J.M.6
Shibahara, S.7
Itoh, K.8
Yamamoto, M.9
-
123
-
-
0037183998
-
The Keap1 BTB/POZ di-merization function is required to sequester Nrf2 in cyto-plasm
-
Zipper LM and Mulcahy RT. The Keap1 BTB/POZ di-merization function is required to sequester Nrf2 in cyto-plasm. J Biol Chem 277: 36544-36552, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
|