-
1
-
-
33644517508
-
3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha
-
Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, Wlodarczyk B, et al. (2006) 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res 66:2459-2467.
-
(2006)
Cancer Res
, vol.66
, pp. 2459-2467
-
-
Abdelrahim, M.1
Ariazi, E.2
Kim, K.3
Khan, S.4
Barhoumi, R.5
Burghardt, R.6
Liu, S.7
Hill, D.8
Finnell, R.9
Wlodarczyk, B.10
-
2
-
-
0033049171
-
Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells
-
Arcaro KF, O'Keefe PW, Yang Y, Clayton W, and Gierthy JF (1999) Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells. Toxicology 133:115-127.
-
(1999)
Toxicology
, vol.133
, pp. 115-127
-
-
Arcaro, K.F.1
O'Keefe, P.W.2
Yang, Y.3
Clayton, W.4
Gierthy, J.F.5
-
3
-
-
0025050740
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibition of 17 beta-estradiol-induced increases in rat uterine epidermal growth factor receptor binding activity and gene expression
-
Astroff B, Rowlands C, Dickerson R, and Safe S (1990) 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibition of 17 beta-estradiol-induced increases in rat uterine epidermal growth factor receptor binding activity and gene expression. Mol Cell Endocrinol 72:247-252.
-
(1990)
Mol Cell Endocrinol
, vol.72
, pp. 247-252
-
-
Astroff, B.1
Rowlands, C.2
Dickerson, R.3
Safe, S.4
-
4
-
-
0030731796
-
Characterization of the "estrogenicity" of tamoxifen and raloxifene in HepG2 cells: Regulation of gene expression from an ERE controlled reporter vector versus regulation of the endogenous SHBG and PS2 genes
-
Barkhem T, Andersson-Ross C, Hoglund M, and Nilsson S (1997) Characterization of the "estrogenicity" of tamoxifen and raloxifene in HepG2 cells: regulation of gene expression from an ERE controlled reporter vector versus regulation of the endogenous SHBG and PS2 genes. J Steroid Biochem Mol Biol 62:53-64.
-
(1997)
J Steroid Biochem Mol Biol
, vol.62
, pp. 53-64
-
-
Barkhem, T.1
Andersson-Ross, C.2
Hoglund, M.3
Nilsson, S.4
-
5
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
6
-
-
31444453937
-
Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines
-
Brandon EF, Bosch TM, Deenen MJ, Levink R, van der Wal E, van Meerveld JB, Bijl M, Beijnen JH, Schellens JH, and Meijerman I (2006) Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines. Toxicol Appl Pharmacol 211:1-10.
-
(2006)
Toxicol Appl Pharmacol
, vol.211
, pp. 1-10
-
-
Brandon, E.F.1
Bosch, T.M.2
Deenen, M.J.3
Levink, R.4
van der Wal, E.5
van Meerveld, J.B.6
Bijl, M.7
Beijnen, J.H.8
Schellens, J.H.9
Meijerman, I.10
-
7
-
-
0037637542
-
The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription
-
Brunnberg S, Pettersson K, Rydin E, Matthews J, Hanberg A, and Pongratz I (2003) The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription. Proc Natl Acad Sci U S A 100:6517-6522.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 6517-6522
-
-
Brunnberg, S.1
Pettersson, K.2
Rydin, E.3
Matthews, J.4
Hanberg, A.5
Pongratz, I.6
-
8
-
-
0035834974
-
Identification of estrogen-induced genes downregulated by AhR agonists in MCF-7 breast cancer cells using suppression subtractive hybridization
-
Chen I, Hsieh T, Thomas T, and Safe S (2001) Identification of estrogen-induced genes downregulated by AhR agonists in MCF-7 breast cancer cells using suppression subtractive hybridization. Gene 262:207-214.
-
(2001)
Gene
, vol.262
, pp. 207-214
-
-
Chen, I.1
Hsieh, T.2
Thomas, T.3
Safe, S.4
-
9
-
-
0442279183
-
Estrogen receptor functional activity changes during differentiation of mammary epithelial cells
-
Faulds MH, Olsen H, Helguero LA, Gustafsson JA, and Haldosen LA (2004) Estrogen receptor functional activity changes during differentiation of mammary epithelial cells. Mol Endocrinol 18:412-421.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 412-421
-
-
Faulds, M.H.1
Olsen, H.2
Helguero, L.A.3
Gustafsson, J.A.4
Haldosen, L.A.5
-
10
-
-
0030245635
-
Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity
-
Fernandez-Salguero PM, Hilbert DM, Rudikoff S, Ward JM, and Gonzalez FJ (1996) Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity. Toxicol Appl Pharmacol 140:173-179.
-
(1996)
Toxicol Appl Pharmacol
, vol.140
, pp. 173-179
-
-
Fernandez-Salguero, P.M.1
Hilbert, D.M.2
Rudikoff, S.3
Ward, J.M.4
Gonzalez, F.J.5
-
11
-
-
0035912592
-
Interaction of PAH-related compounds with the alpha and beta isoforms of the estrogen receptor
-
Fertuck KC, Kumar S, Sikka HC, Matthews JB, and Zacharewski TR (2001) Interaction of PAH-related compounds with the alpha and beta isoforms of the estrogen receptor. Toxicol Lett 121:167-177.
-
(2001)
Toxicol Lett
, vol.121
, pp. 167-177
-
-
Fertuck, K.C.1
Kumar, S.2
Sikka, H.C.3
Matthews, J.B.4
Zacharewski, T.R.5
-
12
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
Gronemeyer H, Gustafsson JA, and Laudet V (2004) Principles for modulation of the nuclear receptor superfamily. Nat Rev Drug Discov 3:950-964.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 950-964
-
-
Gronemeyer, H.1
Gustafsson, J.A.2
Laudet, V.3
-
13
-
-
0034116376
-
The PAS superfamily: Sensors of environmental and developmental signals
-
Gu YZ, Hogenesch JB, and Bradfield CA (2000) The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol 40:519-561.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 519-561
-
-
Gu, Y.Z.1
Hogenesch, J.B.2
Bradfield, C.A.3
-
14
-
-
1842627852
-
Phase I and II enzyme characterization of two sources of HepG2 cell lines
-
Hewitt NJ and Hewitt P (2004) Phase I and II enzyme characterization of two sources of HepG2 cell lines. Xenobiotica 34:243-256.
-
(2004)
Xenobiotica
, vol.34
, pp. 243-256
-
-
Hewitt, N.J.1
Hewitt, P.2
-
15
-
-
0029918651
-
Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling
-
Kharat I and Saatcioglu F (1996) Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling. J Biol Chem 271:10533-10537.
-
(1996)
J Biol Chem
, vol.271
, pp. 10533-10537
-
-
Kharat, I.1
Saatcioglu, F.2
-
16
-
-
0037098451
-
Conditional expression of a constitutively active aryl hydrocarbon receptor in MCF-7 human breast cancer cells
-
Köhle C, Hassepass I, Bock-Hennig BS, Walter Bock K, Poellinger L, and McGuire J (2002) Conditional expression of a constitutively active aryl hydrocarbon receptor in MCF-7 human breast cancer cells. Arch Biochem Biophys 402:172-179.
-
(2002)
Arch Biochem Biophys
, vol.402
, pp. 172-179
-
-
Köhle, C.1
Hassepass, I.2
Bock-Hennig, B.S.3
Walter Bock, K.4
Poellinger, L.5
McGuire, J.6
-
17
-
-
0031241140
-
Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
-
Mimura J, Yamashita K, Nakamura K, Morita M, Takagi TN, Nakao K, Ema M, Sogawa K, Yasuda M, Katsuki M, et al. (1997) Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells 2:645-654.
-
(1997)
Genes Cells
, vol.2
, pp. 645-654
-
-
Mimura, J.1
Yamashita, K.2
Nakamura, K.3
Morita, M.4
Takagi, T.N.5
Nakao, K.6
Ema, M.7
Sogawa, K.8
Yasuda, M.9
Katsuki, M.10
-
18
-
-
0025053559
-
Metabolism of the carcinogen 3-methylcholanthrene in human bone marrow preparations
-
Myers SR and Flesher JW (1990) Metabolism of the carcinogen 3-methylcholanthrene in human bone marrow preparations. Drug Metab Dispos 18:664-669.
-
(1990)
Drug Metab Dispos
, vol.18
, pp. 664-669
-
-
Myers, S.R.1
Flesher, J.W.2
-
19
-
-
0034783960
-
Mechanisms of estrogen action
-
Nilsson S, Makela S, Treuter E, Tujague M, Thomsen J, Andersson G, Enmark E, Pettersson K, Warner M, and Gustafsson JA (2001) Mechanisms of estrogen action. Physiol Rev 81:1535-1565.
-
(2001)
Physiol Rev
, vol.81
, pp. 1535-1565
-
-
Nilsson, S.1
Makela, S.2
Treuter, E.3
Tujague, M.4
Thomsen, J.5
Andersson, G.6
Enmark, E.7
Pettersson, K.8
Warner, M.9
Gustafsson, J.A.10
-
20
-
-
0038100188
-
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
-
Ohtake F, Takeyama K, Matsumoto T, Kitagawa H, Yamamoto Y, Nohara K, Tohyama C, Krust A, Mimura J, Chambon P, et al. (2003) Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423:545-550.
-
(2003)
Nature
, vol.423
, pp. 545-550
-
-
Ohtake, F.1
Takeyama, K.2
Matsumoto, T.3
Kitagawa, H.4
Yamamoto, Y.5
Nohara, K.6
Tohyama, C.7
Krust, A.8
Mimura, J.9
Chambon, P.10
-
21
-
-
0020010617
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
-
Poland A and Knutson JC (1982) 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 22:517-554.
-
(1982)
Annu Rev Pharmacol Toxicol
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
22
-
-
0035977882
-
Molecular biology of the Ah receptor and its role in carcinogenesis
-
Safe S (2001) Molecular biology of the Ah receptor and its role in carcinogenesis. Toxicol Lett 120:1-7.
-
(2001)
Toxicol Lett
, vol.120
, pp. 1-7
-
-
Safe, S.1
-
23
-
-
0029195930
-
Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression
-
Safe S and Krishnan V (1995) Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression. Arch Toxicol Suppl 17:99-115.
-
(1995)
Arch Toxicol Suppl
, vol.17
, pp. 99-115
-
-
Safe, S.1
Krishnan, V.2
-
24
-
-
0034485357
-
Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells
-
Safe S, Wormke M, and Samudio I (2000) Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. J Mammary Gland Biol Neoplasia 5:295-306.
-
(2000)
J Mammary Gland Biol Neoplasia
, vol.5
, pp. 295-306
-
-
Safe, S.1
Wormke, M.2
Samudio, I.3
-
25
-
-
0025153350
-
Metabolism of 2S-hydroxy-3-methylcholanthrene by rat liver microsomes
-
Shou MG and Yang SK (1990) Metabolism of 2S-hydroxy-3-methylcholanthrene by rat liver microsomes. Carcinogenesis 11:2037-2045.
-
(1990)
Carcinogenesis
, vol.11
, pp. 2037-2045
-
-
Shou, M.G.1
Yang, S.K.2
-
26
-
-
0042904900
-
Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties
-
Wilkening S, Stahl F, and Bader A (2003) Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. Drug Metab Dispos 31:1035-1042.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1035-1042
-
-
Wilkening, S.1
Stahl, F.2
Bader, A.3
-
27
-
-
0028285855
-
Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced pS2 expression
-
Zacharewski TR, Bondy KL, McDonell P, and Wu ZF (1994) Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced pS2 expression. Cancer Res 54:2707-2713.
-
(1994)
Cancer Res
, vol.54
, pp. 2707-2713
-
-
Zacharewski, T.R.1
Bondy, K.L.2
McDonell, P.3
Wu, Z.F.4
|