A comparative study of using comet assay and γH2AX foci formation in the detection of N-methyl-N′-nitro-N-nitrosoguanidine-induced DNA damage

Toxicology in Vitro

Volumn 20, Issue 6, 2006, Pages 959-965

  Yu, Yanke ^a   Zhu, Wen ^a   Diao, Huiling ^a   Zhou, Chunxian ^a   Chen, Fanqing F ^b   Yang, Jun ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Comet assay; Double strand breaks; H2AX; N methyl N nitro N nitrosoguanidine; Phosphatidylinositol 3 kinase family

Indexed keywords

ALKALI; HISTONE H2AX; ISOPROTEIN; METHYLNITRONITROSOGUANIDINE;

ACCURACY; AMNION CELL; ARTICLE; CELL NUCLEUS; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; FLUORESCENCE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; STAINING;

CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; HISTONES; HUMANS; METHYLNITRONITROSOGUANIDINE; MICROSCOPY, FLUORESCENCE;

EID: 33745215101     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.01.004     Document Type: Article

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