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Volumn 25, Issue 1, 2010, Pages 57-62

Assessment of in vivo genotoxicity of the rodent carcinogen furan: Evaluation of DNA damage and induction of micronuclei in mouse splenocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; FURAN; HISTONE H2AX;

EID: 73649144555     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gep043     Document Type: Article
Times cited : (50)

References (25)
  • 1
    • 34547865431 scopus 로고
    • Toxicology and carcinogenesis studies of furan (CAS No. 110-00-9) in F344/N rats and B6C3Fl mice (gavage studies)
    • National Toxicology Program U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC
    • National Toxicology Program (1993) Toxicology and carcinogenesis studies of furan (CAS No. 110-00-9) in F344/N rats and B6C3Fl mice (gavage studies). NTP Technical Report No. 402. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.
    • (1993) NTP Technical Report No. 402
  • 4
    • 34547871290 scopus 로고    scopus 로고
    • Data requirements for risk assessment of furan in food
    • Heppner, C. W. and Schlatter, J. R. (2007) Data requirements for risk assessment of furan in food. Food Addit. Contam., 24 (Suppl. 1), 114-121.
    • (2007) Food Addit. Contam. , vol.24 , Issue.SUPPL. 1 , pp. 114-121
    • Heppner, C.W.1    Schlatter, J.R.2
  • 5
    • 34250158586 scopus 로고    scopus 로고
    • Report of the Scientific Panel on Contaminants in the Food Chain on provisional findings on furan in food
    • European Food Safety Authority
    • European Food Safety Authority (2004) Report of the Scientific Panel on Contaminants in the Food Chain on provisional findings on furan in food. EFSA J., 137, 1-20.
    • (2004) EFSA J , vol.137 , pp. 1-20
  • 8
    • 0033914808 scopus 로고    scopus 로고
    • A reactive metabolite of furan, cis-2-butene-1,4-dial is mutagenic in the Ames assay
    • Peterson, L. A., Naruko, K. C. and Predecki, D. P. (2000) A reactive metabolite of furan, cis-2-butene-1,4-dial is mutagenic in the Ames assay. Chem. Res. Toxicol., 13, 531-534.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 531-534
    • Peterson, L.A.1    Naruko, K.C.2    Predecki, D.P.3
  • 9
    • 0021732385 scopus 로고
    • DNA-damaging activity of biotic and xenobiotic aldehydes in Chinese hamster ovary cells
    • Marinari, U. M., Ferro, M., Sciaba, F. et al. (1984) DNA-damaging activity of biotic and xenobiotic aldehydes in Chinese hamster ovary cells. Cell Biochem. Funct., 2, 243-248.
    • (1984) Cell Biochem. Funct. , vol.2 , pp. 243-248
    • Marinari, U.M.1    Ferro, M.2    Sciaba, F.3
  • 10
    • 56249144108 scopus 로고    scopus 로고
    • Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk +/-mouse lymphoma cells
    • Kellert, M., Brink, A., Richter, I. et al. (2008) Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk +/-mouse lymphoma cells. Mutat. Res., 657, 127-132.
    • (2008) Mutat. Res. , vol.657 , pp. 127-132
    • Kellert, M.1    Brink, A.2    Richter, I.3
  • 11
    • 30344443429 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency, Washington, DC accessed October 9, 2009
    • U.S. Environmental Protection Agency (2005) Guidelines for Carcinogen Risk Assessment. U.S. Environmental Protection Agency, Washington, DC http://www.epa.gov/cancerguidelines (accessed October 9, 2009).
    • (2005) Guidelines for Carcinogen Risk Assessment
  • 12
    • 0028306101 scopus 로고
    • Validation of the in vivo CD1 mouse splenocyte micronucleus test
    • Benning, V., Brault, D., Duvinage, C. et al. (1994) Validation of the in vivo CD1 mouse splenocyte micronucleus test. Mutagenesis, 9, 199-204.
    • (1994) Mutagenesis , vol.9 , pp. 199-204
    • Benning, V.1    Brault, D.2    Duvinage, C.3
  • 13
    • 0026593221 scopus 로고
    • Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes
    • Fenech, M. and Neville, S. (1992) Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen., 19, 27-36.
    • (1992) Environ. Mol. Mutagen. , vol.19 , pp. 27-36
    • Fenech, M.1    Neville, S.2
  • 14
    • 0032875309 scopus 로고    scopus 로고
    • Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: Analysis by alkaline single cell gel electrophoresis and cytogenetic methods
    • Andreoli, C., Leopardi, P., Rossi, S. and Crebelli, R. (1999) Processing of DNA damage induced by hydrogen peroxide and methyl methanesulfonate in human lymphocytes: analysis by alkaline single cell gel electrophoresis and cytogenetic methods. Mutagenesis, 14, 497-504.
    • (1999) Mutagenesis , vol.14 , pp. 497-504
    • Andreoli, C.1    Leopardi, P.2    Rossi, S.3    Crebelli, R.4
  • 15
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N. P., McCoy, M. T., Tice, R. R. and Schneider, E. L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 16
    • 0031797733 scopus 로고    scopus 로고
    • Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis
    • Merck, O. and Speit, G. (1998) Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis. Environ. Mol. Mutagen., 32, 260-268.
    • (1998) Environ. Mol. Mutagen. , vol.32 , pp. 260-268
    • Merck, O.1    Speit, G.2
  • 17
    • 33846817437 scopus 로고    scopus 로고
    • Furan is not genotoxic in the micronucleus assay in vivo or in vitro
    • Durling, L. J., Svensson, K. and Abramsson-Zetterberg, L. (2007) Furan is not genotoxic in the micronucleus assay in vivo or in vitro. Toxicol Lett., 169, 43-50.
    • (2007) Toxicol Lett , vol.169 , pp. 43-50
    • Durling, L.J.1    Svensson, K.2    Abramsson-Zetterberg, L.3
  • 18
    • 0026750827 scopus 로고
    • Detection of micronuclei after exposure to mitomycin C, cyclophosphamide and diethylnitrosamine by the in vivo micronucleus test in mouse splenocytes
    • Benning, V., Depasse, F., Melcion, C. and Cordier, A. (1992) Detection of micronuclei after exposure to mitomycin C, cyclophosphamide and diethylnitrosamine by the in vivo micronucleus test in mouse splenocytes. Mutat. Res., 280, 137-142.
    • (1992) Mutat. Res. , vol.280 , pp. 137-142
    • Benning, V.1    Depasse, F.2    Melcion, C.3    Cordier, A.4
  • 19
    • 10844243981 scopus 로고    scopus 로고
    • The formation of substituted 1, N6-etheno-2'-deoxyadenosine and 1, N2-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan
    • Byrns, M. C., Vu, C. C. and Peterson, L. (2004) The formation of substituted 1, N6-etheno-2'-deoxyadenosine and 1, N2-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan. Chem. Res. Toxicol., 17, 1607-1613.
    • (2004) Chem. Res. Toxicol. , vol.17 , pp. 1607-1613
    • Byrns, M.C.1    Vu, C.C.2    Peterson, L.3
  • 20
    • 33845432139 scopus 로고    scopus 로고
    • Electrophilic intermediates produced by bioactivation of furan
    • Peterson, L. A. (2006) Electrophilic intermediates produced by bioactivation of furan. Drug Metab. Rev., 38, 615-626.
    • (2006) Drug Metab. Rev. , vol.38 , pp. 615-626
    • Peterson, L.A.1
  • 21
    • 33644623520 scopus 로고    scopus 로고
    • Formation and repair of interstrand cross-links in DNA
    • Noll, D. M., Manson, T. M. and Muller, P. S. (2006) Formation and repair of interstrand cross-links in DNA. Chem. Rev., 106, 277-301.
    • (2006) Chem. Rev. , vol.106 , pp. 277-301
    • Noll, D.M.1    Manson, T.M.2    Muller, P.S.3
  • 22
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation of serine 139
    • Rogakou, E. P., Pilch, D. R., Orr, A. H. et al. (1998) DNA double-stranded breaks induce histone H2AX phosphorylation of serine 139. J. Biol. Chem., 273, 5858-5868.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3
  • 23
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou, E. P., Bonn, C., Redon, C. and Bonner, W. M. (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol., 146, 905-916.
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Bonn, C.2    Redon, C.3    Bonner, W.M.4
  • 24
    • 66249084554 scopus 로고    scopus 로고
    • Kinetics of H2AX phosphorylation after exposure to cisplatin
    • Olive, P. L. and Banáth, J. P. (2009) Kinetics of H2AX phosphorylation after exposure to cisplatin. Cytometry B Clin. Cytom., 76, 79-90.
    • (2009) Cytometry B Clin. Cytom. , vol.76 , pp. 79-90
    • Olive, P.L.1    Banáth, J.P.2
  • 25
    • 56249128207 scopus 로고    scopus 로고
    • Low sensitivity of the comet assay to detect acetaldehyde-induced genotoxicity
    • Speit, G., Fröhler-Keller, M., Schütz, P. and Neuss, S. (2008) Low sensitivity of the comet assay to detect acetaldehyde-induced genotoxicity. Mutat. Res., 657, 93-97.
    • (2008) Mutat. Res. , vol.657 , pp. 93-97
    • Speit, G.1    Fröhler-Keller, M.2    Schütz, P.3    Neuss, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.