Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 657, Issue 2, 2008, Pages 133-139

  Winter, Heike K ^a   Ehrlich, Veronika A ^a   Grusch, Michael ^a   Lackner, Andreas ^a   Schulte Hermann, Rolf ^a   Grasl Kraupp, Bettina ^a   Mikulits, Wolfgang ^a   Knasmüller, Siegfried ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Comet assay; Enzyme expression; Genotoxic carcinogens; Human hepatoma cells; Metabolic activation

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 3 AMINO 1,4 DIMETHYL 5H PYRIDO[4,3 B]INDOLE; AFLATOXIN B1; BENZO[A]PYRENE; CARCINOGEN; DRUG METABOLIZING ENZYME; HYDROGEN PEROXIDE; NITROSAMINE N NITROSODIMETHYLAMINE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; CANCER CELL CULTURE; CELL ISOLATION; COMET ASSAY; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMOBILIZED CELL; METABOLIC ACTIVATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CELL LINE; CELL LINE, TUMOR; COMET ASSAY; HUMANS; LIVER; LIVER NEOPLASMS; MUTAGENS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 56249086796     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.08.012     Document Type: Article

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