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Volumn 57, Issue 8, 2010, Pages 381-390

Insulin resistance as a mechanism of adaptation during human evolution;La resistencia a la insulina como mecanismo de adaptación durante la evolución humana

Author keywords

Diabetes mellitus; Evolution; Insulin resistance; Microbiota; Obesity

Indexed keywords

INSULIN;

EID: 77957252375     PISSN: 15750922     EISSN: 15792021     Source Type: Journal    
DOI: 10.1016/j.endonu.2010.05.003     Document Type: Short Survey
Times cited : (3)

References (146)
  • 1
    • 33748472083 scopus 로고    scopus 로고
    • A commentary on neuronal degeneration and cell death in Guam ALS and PD: An evolutionary process of understanding
    • Garruto R.M. A commentary on neuronal degeneration and cell death in Guam ALS and PD: An evolutionary process of understanding. Curr Alzheimer Res 2006, 3:397-401.
    • (2006) Curr Alzheimer Res , vol.3 , pp. 397-401
    • Garruto, R.M.1
  • 2
    • 33749361499 scopus 로고    scopus 로고
    • Gene regulatory networks in the evolution and development of the heart
    • Olson E.N. Gene regulatory networks in the evolution and development of the heart. Science 2006, 313:1922-1927.
    • (2006) Science , vol.313 , pp. 1922-1927
    • Olson, E.N.1
  • 3
    • 33845394000 scopus 로고    scopus 로고
    • From latent incubation launched into hostile symptomatic pathology: A probable survival strategy for common respiratory infectious agents
    • Mingomataj E.C., Rudzeviciene O. From latent incubation launched into hostile symptomatic pathology: A probable survival strategy for common respiratory infectious agents. Med Hypotheses 2007, 68:397-400.
    • (2007) Med Hypotheses , vol.68 , pp. 397-400
    • Mingomataj, E.C.1    Rudzeviciene, O.2
  • 4
    • 33947260958 scopus 로고    scopus 로고
    • Haptoglobin 1-1 genotype and the risk of life-threatening Streptococcus infection: Evolutionary implications
    • Wasserzug O., Blum S., Klement E., Lejbkowicz F., Miller-Lotan R., Levy A.P. Haptoglobin 1-1 genotype and the risk of life-threatening Streptococcus infection: Evolutionary implications. J Infect 2007, 54:410.
    • (2007) J Infect , vol.54 , pp. 410
    • Wasserzug, O.1    Blum, S.2    Klement, E.3    Lejbkowicz, F.4    Miller-Lotan, R.5    Levy, A.P.6
  • 5
    • 33646389601 scopus 로고    scopus 로고
    • An evolutionary concept of polycystic ovarian disease: Does evolution favour reproductive success over survival?
    • Gleicher N., Barad D. An evolutionary concept of polycystic ovarian disease: Does evolution favour reproductive success over survival?. Reprod Biomed Online 2006, 12:587-589.
    • (2006) Reprod Biomed Online , vol.12 , pp. 587-589
    • Gleicher, N.1    Barad, D.2
  • 6
    • 33746113794 scopus 로고    scopus 로고
    • Hypertensive disorders of pregnancy are an evolutionary adaptation to mitigate the reproductive consequences of the human physique
    • Ayuk P.T. Hypertensive disorders of pregnancy are an evolutionary adaptation to mitigate the reproductive consequences of the human physique. Med Hypotheses 2006, 67:796-801.
    • (2006) Med Hypotheses , vol.67 , pp. 796-801
    • Ayuk, P.T.1
  • 7
    • 24344505815 scopus 로고    scopus 로고
    • The etiopathogenesis of autoimmunity
    • Mackay I.R. The etiopathogenesis of autoimmunity. Semin Liver Dis 2005, 25:239-250.
    • (2005) Semin Liver Dis , vol.25 , pp. 239-250
    • Mackay, I.R.1
  • 8
    • 14944342522 scopus 로고    scopus 로고
    • The degeneration of dopamine neurons in Parkinson's disease: Insights from embryology and evolution of the mesostriatocortical system
    • Vernier P., Moret F., Callier S., Snapyan M., Wersinger C., Sidhu A. The degeneration of dopamine neurons in Parkinson's disease: Insights from embryology and evolution of the mesostriatocortical system. Ann N Y Acad Sci 2004, 1035:231-249.
    • (2004) Ann N Y Acad Sci , vol.1035 , pp. 231-249
    • Vernier, P.1    Moret, F.2    Callier, S.3    Snapyan, M.4    Wersinger, C.5    Sidhu, A.6
  • 9
    • 0345529921 scopus 로고    scopus 로고
    • Integrated evolutionary, immunological, and neuroendocrine framework for the pathogenesis of chronic disabling inflammatory diseases
    • Straub R.H., Besedovsky H.O. Integrated evolutionary, immunological, and neuroendocrine framework for the pathogenesis of chronic disabling inflammatory diseases. FASEB J 2003, 17:2176-2183.
    • (2003) FASEB J , vol.17 , pp. 2176-2183
    • Straub, R.H.1    Besedovsky, H.O.2
  • 10
    • 0036515448 scopus 로고    scopus 로고
    • Diffuse pulmonary hemorrhage: Evolutionary 'flaw' or consequence of evolutionary progress?
    • Cohen S. Diffuse pulmonary hemorrhage: Evolutionary 'flaw' or consequence of evolutionary progress?. Am J Med Sci 2002, 323:130-139.
    • (2002) Am J Med Sci , vol.323 , pp. 130-139
    • Cohen, S.1
  • 11
    • 0034512243 scopus 로고    scopus 로고
    • Alzheimer's disease and some speculations about the evolution of its modifiers
    • Sapolsky R.M., Finch C.E. Alzheimer's disease and some speculations about the evolution of its modifiers. Ann N Y Acad Sci 2000, 924:99-103.
    • (2000) Ann N Y Acad Sci , vol.924 , pp. 99-103
    • Sapolsky, R.M.1    Finch, C.E.2
  • 12
    • 0027712222 scopus 로고
    • Evolutionary models of quantitative disease risk factors
    • Connor A., Weiss K.M., Weeks S.C. Evolutionary models of quantitative disease risk factors. Hum Biol 1993, 65:917-940.
    • (1993) Hum Biol , vol.65 , pp. 917-940
    • Connor, A.1    Weiss, K.M.2    Weeks, S.C.3
  • 13
    • 45949103489 scopus 로고    scopus 로고
    • Fetal-maternal conflict, trophoblast invasion, preeclampsia, and the red queen
    • Pijnenborg R., Vercruysse L., Hanssens M. Fetal-maternal conflict, trophoblast invasion, preeclampsia, and the red queen. Hypertens Pregnancy 2008, 27:183-196.
    • (2008) Hypertens Pregnancy , vol.27 , pp. 183-196
    • Pijnenborg, R.1    Vercruysse, L.2    Hanssens, M.3
  • 14
    • 39449133661 scopus 로고    scopus 로고
    • Thyroid-adrenergic interactions: Physiological and clinical implications
    • Silva J.E., Bianco S.D. Thyroid-adrenergic interactions: Physiological and clinical implications. Thyroid 2008, 18:157-165.
    • (2008) Thyroid , vol.18 , pp. 157-165
    • Silva, J.E.1    Bianco, S.D.2
  • 15
    • 70949093635 scopus 로고    scopus 로고
    • Some considerations about evolution of idiopathic primary aldosteronism
    • Armanini D., Fiore C. Some considerations about evolution of idiopathic primary aldosteronism. J Endocrinol Invest 2009, 32:623-625.
    • (2009) J Endocrinol Invest , vol.32 , pp. 623-625
    • Armanini, D.1    Fiore, C.2
  • 16
    • 67651036860 scopus 로고    scopus 로고
    • Aneuploidy: From a physiological mechanism of variance to Down syndrome
    • Dierssen M., Herault Y., Estivill X. Aneuploidy: From a physiological mechanism of variance to Down syndrome. Physiol Rev 2009, 89:887-920.
    • (2009) Physiol Rev , vol.89 , pp. 887-920
    • Dierssen, M.1    Herault, Y.2    Estivill, X.3
  • 17
    • 67749084497 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis-evolutionary and other perspectives
    • Eisen A. Amyotrophic lateral sclerosis-evolutionary and other perspectives. Muscle Nerve 2009, 40:297-304.
    • (2009) Muscle Nerve , vol.40 , pp. 297-304
    • Eisen, A.1
  • 18
    • 67651113860 scopus 로고    scopus 로고
    • Enhancing versus suppressive effects of stress on immune function: Implications for immunoprotection and immunopathology
    • Dhabhar F.S. Enhancing versus suppressive effects of stress on immune function: Implications for immunoprotection and immunopathology. Neuroimmunomodulation 2009, 16:300-317.
    • (2009) Neuroimmunomodulation , vol.16 , pp. 300-317
    • Dhabhar, F.S.1
  • 22
    • 65449189111 scopus 로고    scopus 로고
    • Evaluation of iron deficiency as a nutritional adaptation to infectious disease: An evolutionary medicine perspective
    • Wander K., Shell-Duncan B., McDade T.W. Evaluation of iron deficiency as a nutritional adaptation to infectious disease: An evolutionary medicine perspective. Am J Hum Biol 2009, 21:172-179.
    • (2009) Am J Hum Biol , vol.21 , pp. 172-179
    • Wander, K.1    Shell-Duncan, B.2    McDade, T.W.3
  • 24
    • 58249095114 scopus 로고    scopus 로고
    • WHO recognition of the global obesity epidemic
    • James W.P. WHO recognition of the global obesity epidemic. Int J Obes (Lond) 2008, 32:S120-S126.
    • (2008) Int J Obes (Lond) , vol.32
    • James, W.P.1
  • 25
    • 77957263213 scopus 로고    scopus 로고
    • Intenational Diabetes Federation (IDF). Diabetes Atlas (e-Atlas);. [consultado 15/2/2010]. Disponible en:
    • Intenational Diabetes Federation (IDF). Diabetes Atlas (e-Atlas); 2008. [consultado 15/2/2010]. Disponible en: http://www.eatlas.idf.org/index2983.html.
    • (2008)
  • 26
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S., Roglic G., Green A., Sicree R., King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27:1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 27
    • 0034109077 scopus 로고    scopus 로고
    • Obesity, insulin resistance and diabetes--a worldwide epidemic
    • Seidell J.C. Obesity, insulin resistance and diabetes--a worldwide epidemic. Br J Nutr 2000, 83:S5-S8.
    • (2000) Br J Nutr , vol.83
    • Seidell, J.C.1
  • 28
    • 51849146897 scopus 로고    scopus 로고
    • Global burden of obesity in 2005 and projections to 2030
    • Kelly T., Yang W., Chen C.S., Reynolds K., He J. Global burden of obesity in 2005 and projections to 2030. Int J Obes (Lond) 2008, 32:1431-1437.
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1431-1437
    • Kelly, T.1    Yang, W.2    Chen, C.S.3    Reynolds, K.4    He, J.5
  • 29
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers C.D., Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006, 3:e442.
    • (2006) PLoS Med , vol.3
    • Mathers, C.D.1    Loncar, D.2
  • 30
    • 77957284129 scopus 로고    scopus 로고
    • The extended Phenotype: The Long Reach of the Gene. Oxford: Oxford University Press. p. xiii. ISBN 0-19-288051-9.
    • Dawkins R. The extended Phenotype: The Long Reach of the Gene. Oxford: Oxford University Press. p. xiii. ISBN 0-19-288051-9.
    • Dawkins, R.1
  • 31
    • 77957268890 scopus 로고    scopus 로고
    • La peligrosa idea de Darwin: evolución y signifcados de la vida.. Círculo de Lectores. Galaxia Gutenberg, Barcelona.
    • Bennet DC. La peligrosa idea de Darwin: evolución y signifcados de la vida. 1999. Círculo de Lectores. Galaxia Gutenberg, Barcelona.
    • (1999)
    • Bennet, D.C.1
  • 32
    • 0032735973 scopus 로고    scopus 로고
    • Insulin resistance and inflammation in an evolutionary perspective: The contribution of cytokine genotype/phenotype to thriftiness
    • Fernández-Real J.M., Ricart W. Insulin resistance and inflammation in an evolutionary perspective: The contribution of cytokine genotype/phenotype to thriftiness. Diabetologia 1999, 42:1367-1374.
    • (1999) Diabetologia , vol.42 , pp. 1367-1374
    • Fernández-Real, J.M.1    Ricart, W.2
  • 33
    • 70349566593 scopus 로고
    • Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
    • Neel J.V. Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?. Am J Hum Genet 1962, 14:353-362.
    • (1962) Am J Hum Genet , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 34
    • 0026008824 scopus 로고
    • Fetal and infant growth and impaired glucose tolerance at age 64
    • Hales C.N., Barker D.J., Clark P.M., Cox L.J., Fall C., Osmond C., et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991, 303:1019-1022.
    • (1991) BMJ , vol.303 , pp. 1019-1022
    • Hales, C.N.1    Barker, D.J.2    Clark, P.M.3    Cox, L.J.4    Fall, C.5    Osmond, C.6
  • 35
    • 38949142226 scopus 로고    scopus 로고
    • Thrifty energy metabolism in catch-up growth trajectories to insulin and leptin resistance
    • Dulloo A.G. Thrifty energy metabolism in catch-up growth trajectories to insulin and leptin resistance. Best Pract Res Clin Endocrinol Metab 2008, 22:155-171.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , pp. 155-171
    • Dulloo, A.G.1
  • 36
    • 33745024819 scopus 로고    scopus 로고
    • Regulation of fat storage via suppressed thermogenesis: A thrifty phenotype that predisposes individuals with catch-up growth to insulin resistance and obesity
    • Dulloo A.G. Regulation of fat storage via suppressed thermogenesis: A thrifty phenotype that predisposes individuals with catch-up growth to insulin resistance and obesity. Horm Res 2006, 65:90-97.
    • (2006) Horm Res , vol.65 , pp. 90-97
    • Dulloo, A.G.1
  • 37
    • 10744228850 scopus 로고    scopus 로고
    • Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood
    • Bhargava S.K., Sachdev H.S., Fall C.H., Osmond C., Lakshmy R., Barker D.J., et al. Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N Engl J Med 2004, 350:865-875.
    • (2004) N Engl J Med , vol.350 , pp. 865-875
    • Bhargava, S.K.1    Sachdev, H.S.2    Fall, C.H.3    Osmond, C.4    Lakshmy, R.5    Barker, D.J.6
  • 38
    • 27244457374 scopus 로고    scopus 로고
    • Trajectories of growth among children who have coronary events as adults
    • Barker D.J., Osmond C., Forsén T.J., Kajantie E., Eriksson J.G. Trajectories of growth among children who have coronary events as adults. N Engl J Med 2005, 353:1802-1809.
    • (2005) N Engl J Med , vol.353 , pp. 1802-1809
    • Barker, D.J.1    Osmond, C.2    Forsén, T.J.3    Kajantie, E.4    Eriksson, J.G.5
  • 39
    • 33744952660 scopus 로고    scopus 로고
    • Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children
    • Ibáñez L., Ong K., Dunger D.B., De Zegher F. Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab 2006, 91:2153-2158.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2153-2158
    • Ibáñez, L.1    Ong, K.2    Dunger, D.B.3    De Zegher, F.4
  • 40
    • 40849113046 scopus 로고    scopus 로고
    • Early development of visceral fat excess after spontaneous catch-up growth in children with low birth weight
    • Ibáñez L., Suárez L., Lopez-Bermejo A., Díaz M., Valls C., De Zegher F. Early development of visceral fat excess after spontaneous catch-up growth in children with low birth weight. J Clin Endocrinol Metab 2008, 93:925-928.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 925-928
    • Ibáñez, L.1    Suárez, L.2    Lopez-Bermejo, A.3    Díaz, M.4    Valls, C.5    De Zegher, F.6
  • 41
    • 58149234293 scopus 로고    scopus 로고
    • Birth weight and risk of type 2 diabetes: A systematic review
    • Whincup P.H., Kaye S.J., Owen C.G., Huxley R., Cook D.G., Anazawa S., et al. Birth weight and risk of type 2 diabetes: A systematic review. JAMA 2008, 300:2886-2897.
    • (2008) JAMA , vol.300 , pp. 2886-2897
    • Whincup, P.H.1    Kaye, S.J.2    Owen, C.G.3    Huxley, R.4    Cook, D.G.5    Anazawa, S.6
  • 42
    • 40449137038 scopus 로고    scopus 로고
    • Thrifty metabolism that favors fat storage after caloric restriction: A role for skeletal muscle phosphatidylinositol-3-kinase activity and AMP-activated protein kinase
    • Summermatter S., Mainieri D., Russell A.P., Seydoux J., Montani J.P., Buchala A., et al. Thrifty metabolism that favors fat storage after caloric restriction: A role for skeletal muscle phosphatidylinositol-3-kinase activity and AMP-activated protein kinase. FASEB J 2008, 22:774-785.
    • (2008) FASEB J , vol.22 , pp. 774-785
    • Summermatter, S.1    Mainieri, D.2    Russell, A.P.3    Seydoux, J.4    Montani, J.P.5    Buchala, A.6
  • 44
    • 3543146669 scopus 로고    scopus 로고
    • Obesity: The integrated roles of environment and genetics
    • Speakman J.R. Obesity: The integrated roles of environment and genetics. J Nutr 2004, 134:2090S-2105S.
    • (2004) J Nutr , vol.134
    • Speakman, J.R.1
  • 45
    • 0035064229 scopus 로고    scopus 로고
    • Hypothalamic neuropeptide mechanisms for regulating energy balance: From rodent models to human obesity
    • Mercer J.G., Speakman J.R. Hypothalamic neuropeptide mechanisms for regulating energy balance: From rodent models to human obesity. Neurosci Biobehav Rev 2001, 25:101-116.
    • (2001) Neurosci Biobehav Rev , vol.25 , pp. 101-116
    • Mercer, J.G.1    Speakman, J.R.2
  • 46
    • 0035513652 scopus 로고    scopus 로고
    • Control of food intake in the obese
    • Blundell J.E., Gillett A. Control of food intake in the obese. Obes Res 2001, 9:263S-270S.
    • (2001) Obes Res , vol.9
    • Blundell, J.E.1    Gillett, A.2
  • 47
    • 33745503229 scopus 로고    scopus 로고
    • Body mass index and risk of diabetes mellitus in the Asia-Pacific region
    • Asia Pacific Cohort Studies Collaboration
    • Ni Mhurchu C., Parag V., Nakamura M., Patel A., Rodgers A., Lam T.H. Body mass index and risk of diabetes mellitus in the Asia-Pacific region. Asia Pac J Clin Nutr 2006, 15:127-133. Asia Pacific Cohort Studies Collaboration.
    • (2006) Asia Pac J Clin Nutr , vol.15 , pp. 127-133
    • Ni Mhurchu, C.1    Parag, V.2    Nakamura, M.3    Patel, A.4    Rodgers, A.5    Lam, T.H.6
  • 48
    • 33644791703 scopus 로고
    • Obesity in minority populations: An epidemiologic assessment
    • Kumanyika S.K. Obesity in minority populations: An epidemiologic assessment. Obes Res 1994, 2:166-182.
    • (1994) Obes Res , vol.2 , pp. 166-182
    • Kumanyika, S.K.1
  • 49
    • 29244451846 scopus 로고    scopus 로고
    • An overview of obesity and diabetes in the diverse populations of the Pacific
    • Okihiro M., Harrigan R. An overview of obesity and diabetes in the diverse populations of the Pacific. Ethn Dis 2005, 15:S71-S80.
    • (2005) Ethn Dis , vol.15
    • Okihiro, M.1    Harrigan, R.2
  • 50
    • 0037631831 scopus 로고    scopus 로고
    • Insulin resistance and chronic cardiovascular inflammatory syndrome
    • Fernández-Real J.M., Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003, 24:278-301.
    • (2003) Endocr Rev , vol.24 , pp. 278-301
    • Fernández-Real, J.M.1    Ricart, W.2
  • 51
    • 34247522803 scopus 로고    scopus 로고
    • Evolutionary origins of insulin resistance: A behavioral switch hypothesis
    • Watve M.G., Yajnik C.S. Evolutionary origins of insulin resistance: A behavioral switch hypothesis. BMC Evol Biol 2007, 7:61.
    • (2007) BMC Evol Biol , vol.7 , pp. 61
    • Watve, M.G.1    Yajnik, C.S.2
  • 52
    • 0034739050 scopus 로고    scopus 로고
    • Density cycles and an offspring quantity and quality game driven by natural selection
    • Sinervo B., Svensson E., Comendant T. Density cycles and an offspring quantity and quality game driven by natural selection. Nature 2000, 406:985-988.
    • (2000) Nature , vol.406 , pp. 985-988
    • Sinervo, B.1    Svensson, E.2    Comendant, T.3
  • 53
    • 0014739115 scopus 로고
    • Cellular growth of cerebrum, cerebellum and brain stem in normal and merasmic children
    • Winick M., Rosso P., Waterlow J.C. Cellular growth of cerebrum, cerebellum and brain stem in normal and merasmic children. Exp Neurol 1970, 26:393-400.
    • (1970) Exp Neurol , vol.26 , pp. 393-400
    • Winick, M.1    Rosso, P.2    Waterlow, J.C.3
  • 54
    • 0014508299 scopus 로고
    • Malnutrition and brain development
    • Winick M. Malnutrition and brain development. J Pediatr 1969, 74:667-679.
    • (1969) J Pediatr , vol.74 , pp. 667-679
    • Winick, M.1
  • 56
    • 0031915684 scopus 로고    scopus 로고
    • Regional differences in cerebral blood flowand glucose utilization in diabetic man: The effect of insulin
    • Cranston I., Marsden P., Matyka K., Evans M., Lomas J., Sonksen P., et al. Regional differences in cerebral blood flowand glucose utilization in diabetic man: The effect of insulin. J of Cerebral Blood Flow & Metab 1998, 18:130-140.
    • (1998) J of Cerebral Blood Flow & Metab , vol.18 , pp. 130-140
    • Cranston, I.1    Marsden, P.2    Matyka, K.3    Evans, M.4    Lomas, J.5    Sonksen, P.6
  • 57
    • 12144290448 scopus 로고    scopus 로고
    • Role of neuronal insulin resistance in neurodegenerative diseases
    • Schubert M., Gautam D., Surjo D., Ueki K., Baudler S., Schubert D., et al. Role of neuronal insulin resistance in neurodegenerative diseases. PNAS 2004, 101:3100-3105.
    • (2004) PNAS , vol.101 , pp. 3100-3105
    • Schubert, M.1    Gautam, D.2    Surjo, D.3    Ueki, K.4    Baudler, S.5    Schubert, D.6
  • 58
    • 0035947044 scopus 로고    scopus 로고
    • Role of insulin and insulin receptor in learning and memory
    • Zhao W.-Q., Alkon D.L. Role of insulin and insulin receptor in learning and memory. Mol and Cell Endocrinol 2001, 177:125-134.
    • (2001) Mol and Cell Endocrinol , vol.177 , pp. 125-134
    • Zhao, W.-Q.1    Alkon, D.L.2
  • 60
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis Z., Wilson R.S., Bienias J.L., Evans D.A., Bennett D.A. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004, 61:661-666.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 61
    • 1442355804 scopus 로고    scopus 로고
    • Insulin resistance, affective disorders, and Alzheimer's disease: Review and hypothesis
    • Rasgon N., Jarvik L. Insulin resistance, affective disorders, and Alzheimer's disease: Review and hypothesis. J Gerontol 2004, 59A:178-183.
    • (2004) J Gerontol , vol.59 A , pp. 178-183
    • Rasgon, N.1    Jarvik, L.2
  • 63
    • 0033759456 scopus 로고    scopus 로고
    • Why is learning and memory dysfunction in type 2 diabetes limited to older adults
    • Ryan C.M., Geckle M. Why is learning and memory dysfunction in type 2 diabetes limited to older adults. Diabetes Metab Res Rev 2000, 16:308-315.
    • (2000) Diabetes Metab Res Rev , vol.16 , pp. 308-315
    • Ryan, C.M.1    Geckle, M.2
  • 64
  • 65
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • De la Monte S.M. Insulin resistance and Alzheimer's disease. BMB Rep 2009, 42:475-481.
    • (2009) BMB Rep , vol.42 , pp. 475-481
    • De la Monte, S.M.1
  • 68
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 69
    • 0031720795 scopus 로고    scopus 로고
    • Is type II diabetes mellitus a disease of the innate immune system?
    • Pickup J.C., Crook M.A. Is type II diabetes mellitus a disease of the innate immune system?. Diabetologia 1998, 41:1241-1248.
    • (1998) Diabetologia , vol.41 , pp. 1241-1248
    • Pickup, J.C.1    Crook, M.A.2
  • 70
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
    • Pickup J.C. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 2004, 27:813-823.
    • (2004) Diabetes Care , vol.27 , pp. 813-823
    • Pickup, J.C.1
  • 71
    • 12744263365 scopus 로고    scopus 로고
    • Dyslipidemia and inflammation: An evolutionary conserved mechanism
    • Esteve E., Ricart W., Fernández-Real J.M. Dyslipidemia and inflammation: An evolutionary conserved mechanism. Clin Nutr 2005, 24:16-31.
    • (2005) Clin Nutr , vol.24 , pp. 16-31
    • Esteve, E.1    Ricart, W.2    Fernández-Real, J.M.3
  • 72
    • 40749148910 scopus 로고    scopus 로고
    • Innate immunity, insulin resistance and type 2 diabetes
    • Fernández-Real J.M., Pickup J.C. Innate immunity, insulin resistance and type 2 diabetes. Trends Endocrinol Metab 2008, 19:10-16.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 10-16
    • Fernández-Real, J.M.1    Pickup, J.C.2
  • 73
    • 0026791975 scopus 로고
    • The immune system evolved to discriminate infectious nonself from noninfectious self
    • Janeway C.A. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol Today 1992, 13:11-16.
    • (1992) Immunol Today , vol.13 , pp. 11-16
    • Janeway, C.A.1
  • 74
    • 1542373661 scopus 로고    scopus 로고
    • Injury, sepsis, and the regulation of Toll-like receptor responses
    • Murphy T.J., Paterson H.M., Mannick J.A., Lederer J.A. Injury, sepsis, and the regulation of Toll-like receptor responses. J Leukoc Biol 2004, 75:400-407.
    • (2004) J Leukoc Biol , vol.75 , pp. 400-407
    • Murphy, T.J.1    Paterson, H.M.2    Mannick, J.A.3    Lederer, J.A.4
  • 75
    • 56749164791 scopus 로고    scopus 로고
    • Nutrient sensing and inflammation in metabolic diseases
    • Hotamisligil G.S., Erbay E. Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol 2008, 8:923-934.
    • (2008) Nat Rev Immunol , vol.8 , pp. 923-934
    • Hotamisligil, G.S.1    Erbay, E.2
  • 76
    • 0027168655 scopus 로고
    • Homology between the mammalian liver and the Drosophila fat body
    • Søndergaard L. Homology between the mammalian liver and the Drosophila fat body. Trends Genet 1993, 9:193.
    • (1993) Trends Genet , vol.9 , pp. 193
    • Søndergaard, L.1
  • 77
    • 33751235259 scopus 로고    scopus 로고
    • Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes
    • Chung S., Lapoint K., Martinez K., Kennedy A., Boysen Sandberg M., McIntosh MK Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. Endocrinology 2006, 147:5340-5351.
    • (2006) Endocrinology , vol.147 , pp. 5340-5351
    • Chung, S.1    Lapoint, K.2    Martinez, K.3    Kennedy, A.4    Boysen Sandberg, M.5    McIntosh, M.K.6
  • 79
    • 26844502509 scopus 로고    scopus 로고
    • Expression of macrophage-selective markers in human and rodent adipocytes
    • Khazen W., M'bika J.P., Tomkiewicz C., Benelli C., Chany C., Achour A., et al. Expression of macrophage-selective markers in human and rodent adipocytes. FEBS Lett 2005, 579:5631-5634.
    • (2005) FEBS Lett , vol.579 , pp. 5631-5634
    • Khazen, W.1    M'bika, J.P.2    Tomkiewicz, C.3    Benelli, C.4    Chany, C.5    Achour, A.6
  • 80
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R. Origin and physiological roles of inflammation. Nature 2008, 454:428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 81
    • 0035524488 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into Medzhitov R Toll-like receptors and innate immunity
    • Taniguchi C.M., Emanuelli B., Kahn C.R. Critical nodes in signalling pathways: Insights into Medzhitov R Toll-like receptors and innate immunity. Nat Rev Immunol 2001, 1:135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 82
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006, 116:3015-3025.
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 83
    • 44449110675 scopus 로고    scopus 로고
    • Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat
    • Davis J.E., Gabler N.K., Walker-Daniels J., Spurlock M.E. Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) 2008, 16:1248-1255.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1248-1255
    • Davis, J.E.1    Gabler, N.K.2    Walker-Daniels, J.3    Spurlock, M.E.4
  • 85
    • 33846302361 scopus 로고    scopus 로고
    • Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation
    • Suganami T., Mieda T., Itoh M., Shimoda Y., Kamei Y., Ogawa Y. Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochem Biophys Res Commun 2007, 354:45-49.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 45-49
    • Suganami, T.1    Mieda, T.2    Itoh, M.3    Shimoda, Y.4    Kamei, Y.5    Ogawa, Y.6
  • 86
    • 0037836086 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and serum fatty acid composition
    • Fernández-Real J.M., Broch M., Vendrell J., Ricart W. Insulin resistance, inflammation, and serum fatty acid composition. Diabetes Care 2003, 26:1362-1368.
    • (2003) Diabetes Care , vol.26 , pp. 1362-1368
    • Fernández-Real, J.M.1    Broch, M.2    Vendrell, J.3    Ricart, W.4
  • 88
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: insights into insulin action
    • Taniguchi CM, Emanuelli B, Kahn CR Critical nodes in signalling pathways: insights into insulin action. Nature Rev Mol Cell Biol 2006, 7:85-96.
    • (2006) Nature Rev Mol Cell Biol , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 89
    • 65349162278 scopus 로고    scopus 로고
    • Innate recognition of intracellular pathogens: Detection and activation of the first line of defense
    • Rasmussen S.B., Reinert L.S., Paludan S.R. Innate recognition of intracellular pathogens: Detection and activation of the first line of defense. APMIS 2009, 117:323-337.
    • (2009) APMIS , vol.117 , pp. 323-337
    • Rasmussen, S.B.1    Reinert, L.S.2    Paludan, S.R.3
  • 90
    • 66449088641 scopus 로고    scopus 로고
    • Pathogen recognition and inflammatory signaling in innate immune defenses
    • Mogensen T.H. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 2009, 22:240-273.
    • (2009) Clin Microbiol Rev , vol.22 , pp. 240-273
    • Mogensen, T.H.1
  • 91
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • Kawai T., Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 2009, 21:317-337.
    • (2009) Int Immunol , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 95
  • 96
    • 68249111407 scopus 로고    scopus 로고
    • Low serum mannose-binding lectin as a risk factor for new onset diabetes mellitus after renal transplantation
    • Ibernon M., Moreso F., Moreno J.M., Bestard O., Cruzado J.M., Grinyó J.M., et al. Low serum mannose-binding lectin as a risk factor for new onset diabetes mellitus after renal transplantation. Transplantation 2009, 88:272-278.
    • (2009) Transplantation , vol.88 , pp. 272-278
    • Ibernon, M.1    Moreso, F.2    Moreno, J.M.3    Bestard, O.4    Cruzado, J.M.5    Grinyó, J.M.6
  • 97
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • Goldberg R.B. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J Clin Endocrinol Metab 2009, 94:3171-3182.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 98
    • 67049099210 scopus 로고    scopus 로고
    • Human C-reactive protein and the metabolic syndrome
    • Devaraj S., Singh U., Jialal I. Human C-reactive protein and the metabolic syndrome. Curr Opin Lipidol 2009, 20:182-189.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 182-189
    • Devaraj, S.1    Singh, U.2    Jialal, I.3
  • 99
    • 77957276388 scopus 로고    scopus 로고
    • Increase in plasma endotoxin concentrations and the expression of Toll like receptors and suppressor of cytokine signaling-3 in mononuclear cells following a high fat high carbohydrate meal: Implications for insulin resistance
    • En prensa
    • Ghanim H., Abuaysheh S., Sia C.L., Korzeniewski K., Chaudhuri A., Fernández Real J.M., et al. Increase in plasma endotoxin concentrations and the expression of Toll like receptors and suppressor of cytokine signaling-3 in mononuclear cells following a high fat high carbohydrate meal: Implications for insulin resistance. Diabetes Care 2010, En prensa.
    • (2010) Diabetes Care
    • Ghanim, H.1    Abuaysheh, S.2    Sia, C.L.3    Korzeniewski, K.4    Chaudhuri, A.5    Fernández Real, J.M.6
  • 100
    • 33644757817 scopus 로고    scopus 로고
    • Natural antibiotics and insulin sensitivity: The role of bactericidal/permeability-increasing protein
    • Gubern C., López-Bermejo A., Biarnés J., Vendrell J., Ricart W., Fernández-Real J.M. Natural antibiotics and insulin sensitivity: The role of bactericidal/permeability-increasing protein. Diabetes 2006, 55:216-224.
    • (2006) Diabetes , vol.55 , pp. 216-224
    • Gubern, C.1    López-Bermejo, A.2    Biarnés, J.3    Vendrell, J.4    Ricart, W.5    Fernández-Real, J.M.6
  • 101
    • 24944459011 scopus 로고    scopus 로고
    • Opposite relationship between circulating soluble CD14 concentration and endothelial function in diabetic and nondiabetic subjects
    • Fernández-Real J.M., López-Bermejo A., Castro A., Broch M., Peñarroja G., Vendrell J., et al. Opposite relationship between circulating soluble CD14 concentration and endothelial function in diabetic and nondiabetic subjects. Thromb Haemost 2005, 94:615-619.
    • (2005) Thromb Haemost , vol.94 , pp. 615-619
    • Fernández-Real, J.M.1    López-Bermejo, A.2    Castro, A.3    Broch, M.4    Peñarroja, G.5    Vendrell, J.6
  • 104
  • 106
    • 70349088147 scopus 로고    scopus 로고
    • Lactoferrin increases (172Thr) AMPK phosphorylation and insulin-induced (p473Ser) AKT while impairing adipocyte differentiation
    • Moreno-Navarrete J.M., Ortega F.J., Ricart W., Fernández-Real J.M. Lactoferrin increases (172Thr) AMPK phosphorylation and insulin-induced (p473Ser) AKT while impairing adipocyte differentiation. Int J Obes (Lond) 2009, 33:991-1000.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 991-1000
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Ricart, W.3    Fernández-Real, J.M.4
  • 107
    • 70349923422 scopus 로고    scopus 로고
    • Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes
    • Moreno-Navarrete J.M., Ortega F.J., Bassols J., Ricart W., Fernández-Real J.M. Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes. J Clin Endocrinol Metab 2009, 94:4036-4044.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4036-4044
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Bassols, J.3    Ricart, W.4    Fernández-Real, J.M.5
  • 108
    • 48249113844 scopus 로고    scopus 로고
    • Circulating retinol-binding protein-4 concentration might reflect insulin resistance-associated iron overload
    • Fernández-Real J.M., Moreno J.M., Ricart W. Circulating retinol-binding protein-4 concentration might reflect insulin resistance-associated iron overload. Diabetes 2008, 57:1918-1925.
    • (2008) Diabetes , vol.57 , pp. 1918-1925
    • Fernández-Real, J.M.1    Moreno, J.M.2    Ricart, W.3
  • 109
    • 39749199066 scopus 로고    scopus 로고
    • Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status
    • Moreno-Navarrete J.M., Ortega F.J., Bassols J., Castro A., Ricart W., Fernández-Real J.M. Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status. Clin Chem 2008, 54:301-309.
    • (2008) Clin Chem , vol.54 , pp. 301-309
    • Moreno-Navarrete, J.M.1    Ortega, F.J.2    Bassols, J.3    Castro, A.4    Ricart, W.5    Fernández-Real, J.M.6
  • 111
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N., Kihara S., Arita Y., Nishida M., Matsuyama A., Okamoto Y., et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001, 103:1057-1063.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Nishida, M.4    Matsuyama, A.5    Okamoto, Y.6
  • 112
    • 63249106129 scopus 로고    scopus 로고
    • Macrophage content in subcutaneous adipose tissue: Associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians
    • Ortega Martínez de Victoria E., Xu X., Koska J., Francisco A.M., Scalise M., Ferrante A.W., et al. Macrophage content in subcutaneous adipose tissue: Associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians. Diabetes 2009, 58:385-393.
    • (2009) Diabetes , vol.58 , pp. 385-393
    • Ortega Martínez de Victoria, E.1    Xu, X.2    Koska, J.3    Francisco, A.M.4    Scalise, M.5    Ferrante, A.W.6
  • 113
    • 50249116184 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in immunity and autoimmunity
    • Todd D.J., Lee A.H., Glimcher L.H. The endoplasmic reticulum stress response in immunity and autoimmunity. Nature Rev Immunol 2008, 8:663-674.
    • (2008) Nature Rev Immunol , vol.8 , pp. 663-674
    • Todd, D.J.1    Lee, A.H.2    Glimcher, L.H.3
  • 114
    • 33750044112 scopus 로고    scopus 로고
    • Stress and mTORture signaling
    • Reiling J.H., Sabatini D.M. Stress and mTORture signaling. Oncogene 2006, 25:6373-6383.
    • (2006) Oncogene , vol.25 , pp. 6373-6383
    • Reiling, J.H.1    Sabatini, D.M.2
  • 115
    • 35448999348 scopus 로고    scopus 로고
    • Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome
    • Erbay E., Cao H., Hotamisligil G.S. Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome. Curr Atheroscler Rep 2007, 9:222-229.
    • (2007) Curr Atheroscler Rep , vol.9 , pp. 222-229
    • Erbay, E.1    Cao, H.2    Hotamisligil, G.S.3
  • 116
    • 16844379483 scopus 로고    scopus 로고
    • The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities
    • Makowski L., Brittingham K.C., Reynolds J.M., Suttles J., Hotamisligil G.S. The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. J Biol Chem 2005, 280:12888-12895.
    • (2005) J Biol Chem , vol.280 , pp. 12888-12895
    • Makowski, L.1    Brittingham, K.C.2    Reynolds, J.M.3    Suttles, J.4    Hotamisligil, G.S.5
  • 117
    • 4444296764 scopus 로고    scopus 로고
    • Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses
    • Makowski L., Hotamisligil G.S. Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses. J Nutr 2004, 134:2464S-2468S.
    • (2004) J Nutr , vol.134
    • Makowski, L.1    Hotamisligil, G.S.2
  • 118
    • 46749084688 scopus 로고    scopus 로고
    • Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice
    • Furuhashi M., Fucho R., Görgün C.Z., Tuncman G., Cao H., Hotamisligil G.S. Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice. J Clin Invest 2008, 118:2640-2650.
    • (2008) J Clin Invest , vol.118 , pp. 2640-2650
    • Furuhashi, M.1    Fucho, R.2    Görgün, C.Z.3    Tuncman, G.4    Cao, H.5    Hotamisligil, G.S.6
  • 119
    • 0019501740 scopus 로고
    • Immune response in overnutrition
    • Chandra R.K. Immune response in overnutrition. Cancer Res 1981, 41:3795-3796.
    • (1981) Cancer Res , vol.41 , pp. 3795-3796
    • Chandra, R.K.1
  • 120
    • 0037470488 scopus 로고    scopus 로고
    • Evolutionary medicine: From dwarf model systems to healthy centenarians?
    • Longo V.D., Finch C.E. Evolutionary medicine: From dwarf model systems to healthy centenarians?. Science 2003, 299:1342-1346.
    • (2003) Science , vol.299 , pp. 1342-1346
    • Longo, V.D.1    Finch, C.E.2
  • 123
    • 33845602247 scopus 로고    scopus 로고
    • The association of metabolic syndrome and Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus type 1: The Persian Gulf Healthy Heart Study
    • Nabipour I., Vahdat K., Jafari S.M., Pazoki R., Sanjdideh Z. The association of metabolic syndrome and Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus type 1: The Persian Gulf Healthy Heart Study. Cardiovasc Diabetol 2006, 5:25.
    • (2006) Cardiovasc Diabetol , vol.5 , pp. 25
    • Nabipour, I.1    Vahdat, K.2    Jafari, S.M.3    Pazoki, R.4    Sanjdideh, Z.5
  • 124
    • 42049119699 scopus 로고    scopus 로고
    • Association of chronic hepatitis B virus infection with insulin resistance and hepatic steatosis
    • Wang C.C., Hsu C.S., Liu C.J., Kao J.H., Chen D.S. Association of chronic hepatitis B virus infection with insulin resistance and hepatic steatosis. J Gastroenterol Hepatol 2008, 23:779-782.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 779-782
    • Wang, C.C.1    Hsu, C.S.2    Liu, C.J.3    Kao, J.H.4    Chen, D.S.5
  • 126
    • 0142026205 scopus 로고    scopus 로고
    • Inaugural article: Honor thy symbionts
    • Xu J., Gordon J.I. Inaugural article: Honor thy symbionts. PNAS 2003, 100:10452-10459.
    • (2003) PNAS , vol.100 , pp. 10452-10459
    • Xu, J.1    Gordon, J.I.2
  • 127
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • Strober W., Fuss I.J., Blumberg R.S. The immunology of mucosal models of inflammation. Ann Rev Immunology 2002, 20:495-549.
    • (2002) Ann Rev Immunology , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 128
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., Magrini V., Mardis E.R., Gordon J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 129
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: Human gut microbes associated with obesity. Nature 2006, 444:1022-1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 130
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Bäckhed F., Ding H., Wang T., Hooper L.V., Koh G.Y., Nagy A., et al. The gut microbiota as an environmental factor that regulates fat storage. PNAS 2004, 101:15718-15723.
    • (2004) PNAS , vol.101 , pp. 15718-15723
    • Bäckhed, F.1    Ding, H.2    Wang, T.3    Hooper, L.V.4    Koh, G.Y.5    Nagy, A.6
  • 132
    • 33846542071 scopus 로고    scopus 로고
    • Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
    • Bäckhed F., Manchester J.K., Semenkovich C.F., Gordon J.I. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. PNAS 2007, 104:979-984.
    • (2007) PNAS , vol.104 , pp. 979-984
    • Bäckhed, F.1    Manchester, J.K.2    Semenkovich, C.F.3    Gordon, J.I.4
  • 134
    • 58849149821 scopus 로고    scopus 로고
    • Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
    • Milanski M., Degasperi G., Coope A., Morari J., Denis R., Cintra D.E., et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity. J Neurosci 2009, 29:359-370.
    • (2009) J Neurosci , vol.29 , pp. 359-370
    • Milanski, M.1    Degasperi, G.2    Coope, A.3    Morari, J.4    Denis, R.5    Cintra, D.E.6
  • 135
    • 44449110675 scopus 로고    scopus 로고
    • Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat
    • Davis J.E., Gabler N.K., Walker-Daniels J., Spurlock M.E. Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) 2008, 16:1248-1255.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1248-1255
    • Davis, J.E.1    Gabler, N.K.2    Walker-Daniels, J.3    Spurlock, M.E.4
  • 136
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006, 116:3015-3025.
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 137
    • 0003116733 scopus 로고    scopus 로고
    • The Antiquity of Hunter-gatherers
    • Cambridge University Press, Cambridge, C. Panter-Brick, P. Rowley-Conwy, R. Layton (Eds.)
    • Kuhn S.L., Stiner M.C. The Antiquity of Hunter-gatherers. Hunter-gatherers: An interdisciplinary perspective 2001, Cambridge University Press, Cambridge, p. 99-142. C. Panter-Brick, P. Rowley-Conwy, R. Layton (Eds.).
    • (2001) Hunter-gatherers: An interdisciplinary perspective , pp. 99-142
    • Kuhn, S.L.1    Stiner, M.C.2
  • 138
    • 84961466391 scopus 로고
    • Lectins in food: Their importance in health and disease
    • Freed D.L.J. Lectins in food: Their importance in health and disease. J Nutr Med 1991, 2:45-65.
    • (1991) J Nutr Med , vol.2 , pp. 45-65
    • Freed, D.L.J.1
  • 139
    • 0032488367 scopus 로고    scopus 로고
    • Identification of intact peanut lectin in peripheral venous blood
    • Wang Q., Yu L.G., Campbell B.J., Milton J.D., Rhodes J.M. Identification of intact peanut lectin in peripheral venous blood. Lancet 1998, 352:1831-1832.
    • (1998) Lancet , vol.352 , pp. 1831-1832
    • Wang, Q.1    Yu, L.G.2    Campbell, B.J.3    Milton, J.D.4    Rhodes, J.M.5
  • 140
    • 0034088071 scopus 로고    scopus 로고
    • Modulation of immune function by dietary lectins in rheumatoid arthritis
    • Cordain L., Toohey L., Smith M.J., Hickey M.S. Modulation of immune function by dietary lectins in rheumatoid arthritis. Br J Nutr 2000, 83:207-217.
    • (2000) Br J Nutr , vol.83 , pp. 207-217
    • Cordain, L.1    Toohey, L.2    Smith, M.J.3    Hickey, M.S.4
  • 141
    • 0035912884 scopus 로고    scopus 로고
    • The interaction between wheat germ agglutinin and other plant lectins with prostate cancer cells Du-145
    • Gabor F., Klausegger U., Wirth M. The interaction between wheat germ agglutinin and other plant lectins with prostate cancer cells Du-145. Int J Pharm 2001, 221:35-47.
    • (2001) Int J Pharm , vol.221 , pp. 35-47
    • Gabor, F.1    Klausegger, U.2    Wirth, M.3
  • 142
    • 0022545036 scopus 로고
    • Lectin binding to distinguish cell types in fixed atherosclerotic arteries
    • Davis H.R., Glagov S. Lectin binding to distinguish cell types in fixed atherosclerotic arteries. Atherosclerosis 1986, 61:193-203.
    • (1986) Atherosclerosis , vol.61 , pp. 193-203
    • Davis, H.R.1    Glagov, S.2
  • 143
    • 29244490643 scopus 로고    scopus 로고
    • Agrarian diet and diseases of affluence--do evolutionary novel dietary lectins cause leptin resistance?
    • Jönsson T., Olsson S., Ahrén B., Bøg-Hansen T.C., Dole A., Lindeberg S. Agrarian diet and diseases of affluence--do evolutionary novel dietary lectins cause leptin resistance?. BMC Endocr Disord 2005, 5:10.
    • (2005) BMC Endocr Disord , vol.5 , pp. 10
    • Jönsson, T.1    Olsson, S.2    Ahrén, B.3    Bøg-Hansen, T.C.4    Dole, A.5    Lindeberg, S.6
  • 144
    • 33750818180 scopus 로고    scopus 로고
    • A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs
    • Jönsson T., Ahrén B., Pacini G., Sundler F., Wierup N., Steen S., et al. A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs. Nutr Metab (Lond) 2006, 3:39.
    • (2006) Nutr Metab (Lond) , vol.3 , pp. 39
    • Jönsson, T.1    Ahrén, B.2    Pacini, G.3    Sundler, F.4    Wierup, N.5    Steen, S.6
  • 145
    • 34547701720 scopus 로고    scopus 로고
    • A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease
    • Lindeberg S., Jönsson T., Granfeldt Y., Borgstrand E., Soffman J., Sjöström K., et al. A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia 2007, 50:1795-1807.
    • (2007) Diabetologia , vol.50 , pp. 1795-1807
    • Lindeberg, S.1    Jönsson, T.2    Granfeldt, Y.3    Borgstrand, E.4    Soffman, J.5    Sjöström, K.6
  • 146
    • 69049109277 scopus 로고    scopus 로고
    • Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: A randomized cross-over pilot study
    • Jönsson T., Granfeldt Y., Ahrén B., Branell U.C., Pålsson G., Hansson A., et al. Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: A randomized cross-over pilot study. Cardiovasc Diabetol 2009, 8:35.
    • (2009) Cardiovasc Diabetol , vol.8 , pp. 35
    • Jönsson, T.1    Granfeldt, Y.2    Ahrén, B.3    Branell, U.C.4    Pålsson, G.5    Hansson, A.6


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