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Volumn 2010, Issue , 2010, Pages

Therapeutic strategies for SLE involving cytokines: Mechanism-oriented therapies especially IFN-λ targeting gene therapy

Author keywords

[No Author keywords available]

Indexed keywords

ABETIMUS; ADENOVIRUS VECTOR; ALPHA INTERFERON; BETA INTERFERON; CD40 LIGAND MONOCLONAL ANTIBODY; CORTICOSTEROID; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EDRATIDE; GAMMA INTERFERON; IMMUNOLOGIC AGENT; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY BH7; OLIGONUCLEOTIDE; PEPTIDE; PLASMID DNA; PROTEIN TBETA EXR; TOLEROGENIC PEPTIDE; TRANSFORMING GROWTH FACTOR BETA1; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VACCINIA VACCINE;

EID: 77956844800     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2010/461641     Document Type: Review
Times cited : (25)

References (147)
  • 2
    • 0015997305 scopus 로고
    • Immunopathogenesis of systemic lupus erythematosus
    • Koffler D., Immunopathogenesis of systemic lupus erythematosus Annual Review of Medicine 1974 25 149 164
    • (1974) Annual Review of Medicine , vol.25 , pp. 149-164
    • Koffler, D.1
  • 3
    • 42549093135 scopus 로고    scopus 로고
    • Lupus: Improving long-term prognosis
    • Doria A., Briani C., Lupus: improving long-term prognosis Lupus 2008 17 3 166 170
    • (2008) Lupus , vol.17 , Issue.3 , pp. 166-170
    • Doria, A.1    Briani, C.2
  • 4
    • 58649095526 scopus 로고    scopus 로고
    • Novel insights into glucocorticoid-mediated diabetogenic effects: Towards expansion of therapeutic options?
    • Van Raalte D. H., Ouwens D. M., Diamant M., Novel insights into glucocorticoid-mediated diabetogenic effects: towards expansion of therapeutic options? European Journal of Clinical Investigation 2009 39 2 81 93
    • (2009) European Journal of Clinical Investigation , vol.39 , Issue.2 , pp. 81-93
    • Van Raalte, D.H.1    Ouwens, D.M.2    Diamant, M.3
  • 5
    • 74549208358 scopus 로고    scopus 로고
    • Molecular therapies for systemic lupus erythematosus: Clinical trials and future prospects
    • Monneaux F., Muller S., Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects Arthritis Research Therapy 2009 11 3, article 234
    • (2009) Arthritis Research Therapy , vol.11 , Issue.3 ARTICLE 234
    • Monneaux, F.1    Muller, S.2
  • 6
    • 50049125275 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: Future therapeutic avenues
    • Amoura Z., Haroche J., Piette J.-C., Systemic lupus erythematosus: future therapeutic avenues Revue de Medecine Interne 2008 29 9 718 724
    • (2008) Revue de Medecine Interne , vol.29 , Issue.9 , pp. 718-724
    • Amoura, Z.1    Haroche, J.2    Piette, J.-C.3
  • 7
    • 67349261724 scopus 로고    scopus 로고
    • Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): Immunomodulation of gene expression
    • Sthoeger Z. M., Sharabi A., Molad Y., Asher I., Zinger H., Dayan M., Mozes E., Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): immunomodulation of gene expression Journal of Autoimmunity 2009 33 1 77 82
    • (2009) Journal of Autoimmunity , vol.33 , Issue.1 , pp. 77-82
    • Sthoeger, Z.M.1    Sharabi, A.2    Molad, Y.3    Asher, I.4    Zinger, H.5    Dayan, M.6    Mozes, E.7
  • 8
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente L., Richaud-Patin Y., Garca-Padilla C., Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus Arthritis Rheumatism 2000 43 1790 1800
    • (2000) Arthritis Rheumatism , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richaud-Patin, Y.2    Garca-Padilla, C.3
  • 9
    • 14044278824 scopus 로고    scopus 로고
    • IFN- induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White)F1 but not in BALB/c mice
    • Mathian A., Weinberg A., Gallegos M., Banchereau J., Koutouzov S., IFN- induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White)F1 but not in BALB/c mice Journal of Immunology 2005 174 5 2499 2506
    • (2005) Journal of Immunology , vol.174 , Issue.5 , pp. 2499-2506
    • Mathian, A.1    Weinberg, A.2    Gallegos, M.3    Banchereau, J.4    Koutouzov, S.5
  • 10
    • 4344617762 scopus 로고    scopus 로고
    • Interferon- in systemic lupus erythematosus
    • Crow M. K., Kirou K. A., Interferon- in systemic lupus erythematosus Current Opinion in Rheumatology 2004 16 5 541 547
    • (2004) Current Opinion in Rheumatology , vol.16 , Issue.5 , pp. 541-547
    • Crow, M.K.1    Kirou, K.A.2
  • 11
    • 0027930909 scopus 로고
    • Interleukin 6 promotes murine lupus in NZB/NZW F 1 mice
    • Finck B. K., Chan B., Wofsy D., Interleukin 6 promotes murine lupus in NZB/NZW F 1 mice Journal of Clinical Investigation 1994 94 2 585 591
    • (1994) Journal of Clinical Investigation , vol.94 , Issue.2 , pp. 585-591
    • Finck, B.K.1    Chan, B.2    Wofsy, D.3
  • 13
    • 70449441060 scopus 로고    scopus 로고
    • Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity
    • Kunz M., Ibrahim S. M., Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity Mediators of Inflammation 2009 2009
    • (2009) Mediators of Inflammation , vol.2009
    • Kunz, M.1    Ibrahim, S.M.2
  • 14
    • 45249097325 scopus 로고    scopus 로고
    • Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity
    • Wong C. K., Lit L. C. W., Tam L. S., Li E. K. M., Wong P. T. Y., Lam C. W. K., Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity Clinical Immunology 2008 127 3 385 393
    • (2008) Clinical Immunology , vol.127 , Issue.3 , pp. 385-393
    • Wong, C.K.1    Lit, L.C.W.2    Tam, L.S.3    Li, E.K.M.4    Wong, P.T.Y.5    Lam, C.W.K.6
  • 18
    • 0036899589 scopus 로고    scopus 로고
    • Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: A randomized, double-blind, placebo-controlled trial
    • Kalunian K. C., Davis JC. Jr., Merrill J. T., Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial Arthritis Rheumatism 2002 46 3251 3258
    • (2002) Arthritis Rheumatism , vol.46 , pp. 3251-3258
    • Kalunian, K.C.1    Davis Jr., J.C.2    Merrill, J.T.3
  • 20
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4- and IL-4 receptor -deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling
    • Mohrs M., Ledermann B., Khler G., Dorfmller A., Gessner A., Brombacher F., Differences between IL-4- and IL-4 receptor -deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling Journal of Immunology 1999 162 12 7302 7308
    • (1999) Journal of Immunology , vol.162 , Issue.12 , pp. 7302-7308
    • Mohrs, M.1    Ledermann, B.2    Khler, G.3    Dorfmller, A.4    Gessner, A.5    Brombacher, F.6
  • 22
    • 44849096534 scopus 로고    scopus 로고
    • Critical role of IL-2 and TGF- in generation, function and stabilization of Foxp3+ CD4+ Treg
    • Horwitz D. A., Zheng S. G., Wang J., Gray J. D., Critical role of IL-2 and TGF- in generation, function and stabilization of Foxp3+ CD4+ Treg European Journal of Immunology 2008 38 4 912 915
    • (2008) European Journal of Immunology , vol.38 , Issue.4 , pp. 912-915
    • Horwitz, D.A.1    Zheng, S.G.2    Wang, J.3    Gray, J.D.4
  • 24
    • 11144339428 scopus 로고    scopus 로고
    • ICAM-1 expression on endothelium and systemic cytokine production in cutaneous neutrophilic leukocytoclastic vasculitis in NZBxNZWF 1 mice
    • Hayashi T., Hasegawa K., Ichinohe N., ICAM-1 expression on endothelium and systemic cytokine production in cutaneous neutrophilic leukocytoclastic vasculitis in NZBxNZWF 1 mice Histology and Histopathology 2005 20 1 45 52
    • (2005) Histology and Histopathology , vol.20 , Issue.1 , pp. 45-52
    • Hayashi, T.1    Hasegawa, K.2    Ichinohe, N.3
  • 25
    • 49349094343 scopus 로고    scopus 로고
    • Ultrastructure of myoepithelial cells as a target cell in sialoadenitis of submandibular glands of lupus-prone female NZBxNZWF 1 mice
    • Hayashi T., Hayashi H., Fujii T., Adachi C., Hasegawa K., Ultrastructure of myoepithelial cells as a target cell in sialoadenitis of submandibular glands of lupus-prone female NZBxNZWF 1 mice Virchows Archiv 2008 453 2 177 188
    • (2008) Virchows Archiv , vol.453 , Issue.2 , pp. 177-188
    • Hayashi, T.1    Hayashi, H.2    Fujii, T.3    Adachi, C.4    Hasegawa, K.5
  • 26
    • 33748447541 scopus 로고    scopus 로고
    • Type i interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J., Pascual V., Type I interferon in systemic lupus erythematosus and other autoimmune diseases Immunity 2006 25 3 383 392
    • (2006) Immunity , vol.25 , Issue.3 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 27
    • 34250162775 scopus 로고    scopus 로고
    • Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells
    • Kang H.-K., Liu M., Datta S. K., Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells Journal of Immunology 2007 178 12 7849 7858
    • (2007) Journal of Immunology , vol.178 , Issue.12 , pp. 7849-7858
    • Kang, H.-K.1    Liu, M.2    Datta, S.K.3
  • 28
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann T. R., Coffman R. L., TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annual Review of Immunology 1989 7 145 173
    • (1989) Annual Review of Immunology , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 29
    • 0035053491 scopus 로고    scopus 로고
    • The role of IFN- in systemic erythematosus: A challenge tothe Th1/Th2 paradigm in autoimmunity
    • Theofilopoulos A. N., Koundouris S., Kono D. H., Lawson B. R., The role of IFN- in systemic erythematosus: a challenge tothe Th1/Th2 paradigm in autoimmunity Arthritis Research 2001 3 3 136 141
    • (2001) Arthritis Research , vol.3 , Issue.3 , pp. 136-141
    • Theofilopoulos, A.N.1    Koundouris, S.2    Kono, D.H.3    Lawson, B.R.4
  • 30
    • 36849075379 scopus 로고    scopus 로고
    • Targeting of Th1-associated chemokine receptors CXCR3 and CCR5 as therapeutic strategy for inflammatory diseases
    • Turner J. E., Steinmetz O. M., Stahl R. A., Panzer U., Targeting of Th1-associated chemokine receptors CXCR3 and CCR5 as therapeutic strategy for inflammatory diseases Mini-Reviews in Medicinal Chemistry 2007 7 11 1089 1096
    • (2007) Mini-Reviews in Medicinal Chemistry , vol.7 , Issue.11 , pp. 1089-1096
    • Turner, J.E.1    Steinmetz, O.M.2    Stahl, R.A.3    Panzer, U.4
  • 32
    • 0028081880 scopus 로고
    • Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice
    • Ishida H., Muchamuel T., Sakaguchi S., Andrade S., Menon S., Howard M., Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice Journal of Experimental Medicine 1994 179 1 305 310
    • (1994) Journal of Experimental Medicine , vol.179 , Issue.1 , pp. 305-310
    • Ishida, H.1    Muchamuel, T.2    Sakaguchi, S.3    Andrade, S.4    Menon, S.5    Howard, M.6
  • 33
    • 0029826107 scopus 로고    scopus 로고
    • CD40-mediated stimulation of B1 and B2 cells: Implication in autoantibody production in murine lupus
    • Kaneko Y., Hirose S., Abe M., Yagita H., Okumura K., Shirai T., CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus European Journal of Immunology 1996 26 12 3061 3065
    • (1996) European Journal of Immunology , vol.26 , Issue.12 , pp. 3061-3065
    • Kaneko, Y.1    Hirose, S.2    Abe, M.3    Yagita, H.4    Okumura, K.5    Shirai, T.6
  • 34
    • 0031065236 scopus 로고    scopus 로고
    • Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice
    • Nakajima A., Hirose S., Yagita H., Okumura K., Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice Journal of Immunology 1997 158 3 1466 1472
    • (1997) Journal of Immunology , vol.158 , Issue.3 , pp. 1466-1472
    • Nakajima, A.1    Hirose, S.2    Yagita, H.3    Okumura, K.4
  • 35
  • 36
    • 0032522778 scopus 로고    scopus 로고
    • IFN- receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice
    • Haas C., Ryffel B., Le Hir M., IFN- receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice Journal of Immunology 1998 160 8 3713 3718
    • (1998) Journal of Immunology , vol.160 , Issue.8 , pp. 3713-3718
    • Haas, C.1    Ryffel, B.2    Le Hir, M.3
  • 37
    • 0037565297 scopus 로고    scopus 로고
    • Using single-gene deletions to identify checkpoints in the progression of systemic autoimmunity
    • Pollard K. M., Hultman P., Kono D. H., Using single-gene deletions to identify checkpoints in the progression of systemic autoimmunity Annals of the New York Academy of Sciences 2003 987 236 239
    • (2003) Annals of the New York Academy of Sciences , vol.987 , pp. 236-239
    • Pollard, K.M.1    Hultman, P.2    Kono, D.H.3
  • 38
    • 0035182394 scopus 로고    scopus 로고
    • Interferon- is required for lupus nephritis in mice treated with the hydrocarbon oil pristane
    • Richards H. B., Satoh M., Jennette J. C., Croker B. P., Yoshida H., Reeves W. H., Interferon- is required for lupus nephritis in mice treated with the hydrocarbon oil pristane Kidney International 2001 60 6 2173 2180
    • (2001) Kidney International , vol.60 , Issue.6 , pp. 2173-2180
    • Richards, H.B.1    Satoh, M.2    Jennette, J.C.3    Croker, B.P.4    Yoshida, H.5    Reeves, W.H.6
  • 46
    • 0036201362 scopus 로고    scopus 로고
    • Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array
    • Rus V., Atamas S. P., Shustova V., Luzina I. G., Selaru F., Magder L. S., Via C. S., Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array Clinical Immunology 2002 102 3 283 290
    • (2002) Clinical Immunology , vol.102 , Issue.3 , pp. 283-290
    • Rus, V.1    Atamas, S.P.2    Shustova, V.3    Luzina, I.G.4    Selaru, F.5    Magder, L.S.6    Via, C.S.7
  • 47
    • 0345306152 scopus 로고    scopus 로고
    • Synthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB NZWF 1 mice
    • Hasegawa K., Hayashi T., Synthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB NZWF 1 mice Lupus 2003 12 11 838 845
    • (2003) Lupus , vol.12 , Issue.11 , pp. 838-845
    • Hasegawa, K.1    Hayashi, T.2
  • 49
  • 50
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul W. E., Seder R. A., Lymphocyte responses and cytokines Cell 1994 76 2 241 251
    • (1994) Cell , vol.76 , Issue.2 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 51
    • 0018192570 scopus 로고
    • Treatment of lupus nephritis in adult (NZB + NZW)F 1 mice by cortisone-facilitated tolerance to nucleic acid antigens
    • Borel Y., Lewis R. M., Andre-Schwartz J., Stollar B. D., Diener E., Treatment of lupus nephritis in adult (NZB + NZW)F 1 mice by cortisone-facilitated tolerance to nucleic acid antigens Journal of Clinical Investigation 1978 61 2 276 286
    • (1978) Journal of Clinical Investigation , vol.61 , Issue.2 , pp. 276-286
    • Borel, Y.1    Lewis, R.M.2    Andre-Schwartz, J.3    Stollar, B.D.4    Diener, E.5
  • 52
    • 0042346153 scopus 로고    scopus 로고
    • Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation
    • Gursel I., Gursel M., Yamada H., Ishii K. J., Takeshita F., Klinman D. M., Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation Journal of Immunology 2003 171 3 1393 1400
    • (2003) Journal of Immunology , vol.171 , Issue.3 , pp. 1393-1400
    • Gursel, I.1    Gursel, M.2    Yamada, H.3    Ishii, K.J.4    Takeshita, F.5    Klinman, D.M.6
  • 53
    • 13444302229 scopus 로고    scopus 로고
    • Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice
    • Dong L., Ito S., Ishii K. J., Klinman D. M., Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice Arthritis and Rheumatism 2005 52 2 651 658
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.2 , pp. 651-658
    • Dong, L.1    Ito, S.2    Ishii, K.J.3    Klinman, D.M.4
  • 54
    • 0037637548 scopus 로고    scopus 로고
    • Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis
    • Zeuner R. A., Verthelyi D., Gursel M., Ishii K. J., Klinman D. M., Influence of stimulatory and suppressive DNA motifs on host susceptibility to inflammatory arthritis Arthritis and Rheumatism 2003 48 6 1701 1707
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.6 , pp. 1701-1707
    • Zeuner, R.A.1    Verthelyi, D.2    Gursel, M.3    Ishii, K.J.4    Klinman, D.M.5
  • 55
    • 0037371208 scopus 로고    scopus 로고
    • Oligodeoxynucleotides without CpG motifs work as adjuvant for the induction of Th2 differentiation in a sequence-independent manner
    • Sano K., Shirota H., Terui T., Hattori T., Tamura G., Oligodeoxynucleotides without CpG motifs work as adjuvant for the induction of Th2 differentiation in a sequence-independent manner Journal of Immunology 2003 170 5 2367 2373
    • (2003) Journal of Immunology , vol.170 , Issue.5 , pp. 2367-2373
    • Sano, K.1    Shirota, H.2    Terui, T.3    Hattori, T.4    Tamura, G.5
  • 56
    • 6344262317 scopus 로고    scopus 로고
    • Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN- - And IL-12-mediated signaling
    • Shirota H., Gursel M., Klinman D. M., Suppressive oligodeoxynucleotides inhibit Th1 differentiation by blocking IFN- -and IL-12-mediated signaling Journal of Immunology 2004 173 8 5002 5007
    • (2004) Journal of Immunology , vol.173 , Issue.8 , pp. 5002-5007
    • Shirota, H.1    Gursel, M.2    Klinman, D.M.3
  • 57
    • 2342491490 scopus 로고    scopus 로고
    • Suppressive oligonucleotides protect against collagen-induced arthritis in mice
    • Dong L., Ito S.-I., Ishii K. J., Klinman D. M., Suppressive oligonucleotides protect against collagen-induced arthritis in mice Arthritis and Rheumatism 2004 50 5 1686 1689
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.5 , pp. 1686-1689
    • Dong, L.1    Ito, S.-I.2    Ishii, K.J.3    Klinman, D.M.4
  • 58
    • 0037899021 scopus 로고    scopus 로고
    • Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice
    • Hayashi T., Yasutomi Y., Hasegawa K., Sasaki Y., Onodera T., Interleukin-4-expressing plasmid DNA inhibits reovirus type-2-triggered autoimmune insulitis in DBA/1 J suckling mice International Journal of Experimental Pathology 2003 84 2 101 106
    • (2003) International Journal of Experimental Pathology , vol.84 , Issue.2 , pp. 101-106
    • Hayashi, T.1    Yasutomi, Y.2    Hasegawa, K.3    Sasaki, Y.4    Onodera, T.5
  • 60
    • 0024857899 scopus 로고
    • Interleukin-4 (B-cell stimulatory factor-1) augments the in vivo generation of cytotoxic cells in immunosuppressed animals
    • Conlon P. J., Tyler S., Grabstein K. H., Morrissey P., Interleukin-4 (B-cell stimulatory factor-1) augments the in vivo generation of cytotoxic cells in immunosuppressed animals Biotechnology Therapeutics 1989 1 1 31 41
    • (1989) Biotechnology Therapeutics , vol.1 , Issue.1 , pp. 31-41
    • Conlon, P.J.1    Tyler, S.2    Grabstein, K.H.3    Morrissey, P.4
  • 64
    • 0025736362 scopus 로고
    • Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia
    • Muller W., Kuhn R., Rajewsky K., Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia European Journal of Immunology 1991 21 4 921 925
    • (1991) European Journal of Immunology , vol.21 , Issue.4 , pp. 921-925
    • Muller, W.1    Kuhn, R.2    Rajewsky, K.3
  • 65
    • 0027472336 scopus 로고
    • Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection
    • Leal L. M. C. C., Moss D. W., Kuhn R., Muller W., Liew F. Y., Interleukin-4 transgenic mice of resistant background are susceptible to Leishmania major infection European Journal of Immunology 1993 23 2 566 569
    • (1993) European Journal of Immunology , vol.23 , Issue.2 , pp. 566-569
    • Leal, L.M.C.C.1    Moss, D.W.2    Kuhn, R.3    Muller, W.4    Liew, F.Y.5
  • 66
    • 0026708718 scopus 로고
    • Regulation of immunity to parasites by T cells and T cell-derived cytokines
    • Sher A., Coffman R. L., Regulation of immunity to parasites by T cells and T cell-derived cytokines Annual Review of Immunology 1992 10 385 409
    • (1992) Annual Review of Immunology , vol.10 , pp. 385-409
    • Sher, A.1    Coffman, R.L.2
  • 67
    • 0343773445 scopus 로고    scopus 로고
    • IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease
    • Rcken M., Racke M., Shevach E. M., IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease Immunology Today 1996 17 5 225 231
    • (1996) Immunology Today , vol.17 , Issue.5 , pp. 225-231
    • Rcken, M.1    Racke, M.2    Shevach, E.M.3
  • 68
    • 36749051248 scopus 로고    scopus 로고
    • Systemic administration of interleukin-4 expressing plasmid DNA delays the development of glomerulonephritis and prolongs survival in lupus-prone female NZB NZW F 1 mice
    • Hayashi T., Hasegawa K., Sasaki Y., Mori T., Adachi C., Maeda K., Systemic administration of interleukin-4 expressing plasmid DNA delays the development of glomerulonephritis and prolongs survival in lupus-prone female NZB NZW F 1 mice Nephrology Dialysis Transplantation 2007 22 11 3131 3138
    • (2007) Nephrology Dialysis Transplantation , vol.22 , Issue.11 , pp. 3131-3138
    • Hayashi, T.1    Hasegawa, K.2    Sasaki, Y.3    Mori, T.4    Adachi, C.5    Maeda, K.6
  • 69
    • 0032504602 scopus 로고    scopus 로고
    • Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice
    • Nitta Y., Tashiro F., Tokui M., Shimada A., Takei I., Tabayashi K., Miyazaki J.-I., Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice Human Gene Therapy 1998 9 12 1701 1707
    • (1998) Human Gene Therapy , vol.9 , Issue.12 , pp. 1701-1707
    • Nitta, Y.1    Tashiro, F.2    Tokui, M.3    Shimada, A.4    Takei, I.5    Tabayashi, K.6    Miyazaki, J.-I.7
  • 70
    • 0036198813 scopus 로고    scopus 로고
    • Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and biodegradable polymeric carrier
    • Lee M., Jae J. K., Han S.-O., Ko K. S., Ki S. W., Prevention of autoimmune insulitis by delivery of interleukin-4 plasmid using a soluble and biodegradable polymeric carrier Pharmaceutical Research 2002 19 3 246 249
    • (2002) Pharmaceutical Research , vol.19 , Issue.3 , pp. 246-249
    • Lee, M.1    Jae, J.K.2    Han, S.-O.3    Ko, K.S.4    Ki, S.W.5
  • 71
    • 0037250461 scopus 로고    scopus 로고
    • Immune modulation by plasmid DNA-mediated cytokine gene transfer
    • Piccirillo C. A., Prud'homme G. J., Immune modulation by plasmid DNA-mediated cytokine gene transfer Current Pharmaceutical Design 2003 9 1 83 94
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.1 , pp. 83-94
    • Piccirillo, C.A.1    Prud'Homme, G.J.2
  • 73
    • 0030273086 scopus 로고    scopus 로고
    • Immune activation by bacterial DNA: A new genetic code
    • Pisetsky D. S., Immune activation by bacterial DNA: a new genetic code Immunity 1996 5 4 303 310
    • (1996) Immunity , vol.5 , Issue.4 , pp. 303-310
    • Pisetsky, D.S.1
  • 74
    • 0036728587 scopus 로고    scopus 로고
    • Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectors
    • Mazda O., Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectors Current Gene Therapy 2002 2 3 379 392
    • (2002) Current Gene Therapy , vol.2 , Issue.3 , pp. 379-392
    • Mazda, O.1
  • 75
    • 0024425654 scopus 로고
    • CD5 + B lymphocytes, polyreactive antibodies and the human B-cell repertoire
    • Casali P., Notkins A. L., CD5 + B lymphocytes, polyreactive antibodies and the human B-cell repertoire Immunology Today 1989 10 11 364 368
    • (1989) Immunology Today , vol.10 , Issue.11 , pp. 364-368
    • Casali, P.1    Notkins, A.L.2
  • 78
    • 0038146960 scopus 로고    scopus 로고
    • Immunopathology and the gene therapy of lupus
    • Mageed R. A., Prud'homme G. J., Immunopathology and the gene therapy of lupus Gene Therapy 2003 10 10 861 874
    • (2003) Gene Therapy , vol.10 , Issue.10 , pp. 861-874
    • Mageed, R.A.1    Prud'Homme, G.J.2
  • 79
    • 0028963222 scopus 로고
    • Experimental therapy of systemic lupus erythematosus: The treatment of NZB/W mice with mouse soluble interferon- receptor inhibits the onset of glomerulonephritis
    • Ozmen L., Roman D., Fountoulakis M., Schmid G., Ryffel B., Garotta G., Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon- receptor inhibits the onset of glomerulonephritis European Journal of Immunology 1995 25 1 6 12
    • (1995) European Journal of Immunology , vol.25 , Issue.1 , pp. 6-12
    • Ozmen, L.1    Roman, D.2    Fountoulakis, M.3    Schmid, G.4    Ryffel, B.5    Garotta, G.6
  • 81
    • 0034220667 scopus 로고    scopus 로고
    • Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors
    • Prud'homme G. J., Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors Journal of Gene Medicine 2000 2 4 222 232
    • (2000) Journal of Gene Medicine , vol.2 , Issue.4 , pp. 222-232
    • Prud'Homme, G.J.1
  • 85
    • 3042620058 scopus 로고    scopus 로고
    • Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus
    • Park M. C., Park Y. B., Lee S. K., Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus Clinical Rheumatology 2004 23 3 225 229
    • (2004) Clinical Rheumatology , vol.23 , Issue.3 , pp. 225-229
    • Park, M.C.1    Park, Y.B.2    Lee, S.K.3
  • 86
    • 33744823535 scopus 로고    scopus 로고
    • Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients
    • Wozniacka A., Lesiak A., Narbutt J., McCauliffe D. P., Sysa-Jedrzejowska A., Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients Lupus 2006 15 5 268 275
    • (2006) Lupus , vol.15 , Issue.5 , pp. 268-275
    • Wozniacka, A.1    Lesiak, A.2    Narbutt, J.3    McCauliffe, D.P.4    Sysa-Jedrzejowska, A.5
  • 87
    • 33845372494 scopus 로고    scopus 로고
    • Injection of IL-12- and IL-18-encoding plasmids ameliorates the autoimmune pathology of MRL/Mp-Tnfrsf6lpr mice: Synergistic effect on autoimmune symptoms
    • Neumann D., Tschernig T., Popa D., Schmiedl A., de Lema G. P., Resch K., Martin M. U., Injection of IL-12- and IL-18-encoding plasmids ameliorates the autoimmune pathology of MRL/Mp-Tnfrsf6lpr mice: synergistic effect on autoimmune symptoms International Immunology 2006 18 12 1779 1787
    • (2006) International Immunology , vol.18 , Issue.12 , pp. 1779-1787
    • Neumann, D.1    Tschernig, T.2    Popa, D.3    Schmiedl, A.4    De Lema, G.P.5    Resch, K.6    Martin, M.U.7
  • 88
    • 0029021257 scopus 로고
    • Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery
    • Raz E., Dudler J., Lotz M., Baird S. M., Berry C. C., Eisenberg R. A., Carson D. A., Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery Lupus 1995 4 4 286 292
    • (1995) Lupus , vol.4 , Issue.4 , pp. 286-292
    • Raz, E.1    Dudler, J.2    Lotz, M.3    Baird, S.M.4    Berry, C.C.5    Eisenberg, R.A.6    Carson, D.A.7
  • 89
    • 0033046191 scopus 로고    scopus 로고
    • Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF- 1 gene therapy using attenuated Salmonella typhimurium as gene carrier
    • Huggins M. L., Huang F.-P., Xu D., Lindop G., Stott D. I., Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF- 1 gene therapy using attenuated Salmonella typhimurium as gene carrier Lupus 1999 8 1 29 38
    • (1999) Lupus , vol.8 , Issue.1 , pp. 29-38
    • Huggins, M.L.1    Huang, F.-P.2    Xu, D.3    Lindop, G.4    Stott, D.I.5
  • 90
    • 0025289913 scopus 로고
    • Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus
    • Gutierrez-Ramos J. C., Andreu J. L., Revilla Y., Vinuela E., Martinez C., Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus Nature 1990 346 6281 271 274
    • (1990) Nature , vol.346 , Issue.6281 , pp. 271-274
    • Gutierrez-Ramos, J.C.1    Andreu, J.L.2    Revilla, Y.3    Vinuela, E.4    Martinez, C.5
  • 92
    • 0033976034 scopus 로고    scopus 로고
    • CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice
    • Takiguchi M., Murakami M., Nakagawa I., Saito I., Hashimoto A., Uede T., CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice Life Sciences 2000 66 11 991 1001
    • (2000) Life Sciences , vol.66 , Issue.11 , pp. 991-1001
    • Takiguchi, M.1    Murakami, M.2    Nakagawa, I.3    Saito, I.4    Hashimoto, A.5    Uede, T.6
  • 94
    • 29144512329 scopus 로고    scopus 로고
    • Prevention and reversal of lupus in NZB/NZW mice by costimulatory blockade with adeno-associated virus-mediated gene transfer
    • Ye X., Zhu T., Bastacky S., McHale T., Li J., Xiao X., Prevention and reversal of lupus in NZB/NZW mice by costimulatory blockade with adeno-associated virus-mediated gene transfer Arthritis and Rheumatism 2005 52 12 3975 3986
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.12 , pp. 3975-3986
    • Ye, X.1    Zhu, T.2    Bastacky, S.3    McHale, T.4    Li, J.5    Xiao, X.6
  • 95
    • 32044445824 scopus 로고    scopus 로고
    • Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice
    • Ding H., Wu X., Wu J., Yagita H., He Y., Zhang J., Ren J., Gao W., Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice Clinical Immunology 2006 118 2-3 258 267
    • (2006) Clinical Immunology , vol.118 , Issue.23 , pp. 258-267
    • Ding, H.1    Wu, X.2    Wu, J.3    Yagita, H.4    He, Y.5    Zhang, J.6    Ren, J.7    Gao, W.8
  • 96
    • 0034927194 scopus 로고    scopus 로고
    • PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
    • Nishimura H., Honjo T., PD-1: an inhibitory immunoreceptor involved in peripheral tolerance Trends in Immunology 2001 22 5 265 268
    • (2001) Trends in Immunology , vol.22 , Issue.5 , pp. 265-268
    • Nishimura, H.1    Honjo, T.2
  • 99
    • 4344568511 scopus 로고    scopus 로고
    • Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger
    • Zhong X., Bai C., Gao W., Strom T. B., Rothstein T. L., Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger International Immunology 2004 16 8 1181 1188
    • (2004) International Immunology , vol.16 , Issue.8 , pp. 1181-1188
    • Zhong, X.1    Bai, C.2    Gao, W.3    Strom, T.B.4    Rothstein, T.L.5
  • 105
    • 33750378268 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: all roads lead to type I interferons
    • DOI 10.1016/j.coi.2006.09.014, PII S0952791506001993
    • Pascual V., Farkas L., Banchereau J., Systemic lupus erythematosus: all roads lead to type I interferons Current Opinion in Immunology 2006 18 6 676 682 (Pubitemid 44635182)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.6 , pp. 676-682
    • Pascual, V.1    Farkas, L.2    Banchereau, J.3
  • 106
    • 62349128189 scopus 로고    scopus 로고
    • Regulatory T cells in systemic lupus erythematosus: Past, present and future
    • Horwitz D. A., Regulatory T cells in systemic lupus erythematosus: past, present and future Arthritis Research and Therapy 2008 10 6, article 227
    • (2008) Arthritis Research and Therapy , vol.10 , Issue.6 ARTICLE 227
    • Horwitz, D.A.1
  • 107
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4 + CD25 + T cell-mediated suppression by dendritic cells
    • Pasare C., Medzhitov R., Toll pathway-dependent blockade of CD4 + CD25 + T cell-mediated suppression by dendritic cells Science 2003 299 5609 1033 1036
    • (2003) Science , vol.299 , Issue.5609 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 109
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu Y.-J., IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors Annual Review of Immunology 2005 23 275 306
    • (2005) Annual Review of Immunology , vol.23 , pp. 275-306
    • Liu, Y.-J.1
  • 110
    • 0141886220 scopus 로고    scopus 로고
    • IFN- skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities
    • Mohty M., Vialle-Castellano A., Nunes J. A., Isnardon D., Olive D., Gaugler B., IFN- skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities Journal of Immunology 2003 171 7 3385 3393
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3385-3393
    • Mohty, M.1    Vialle-Castellano, A.2    Nunes, J.A.3    Isnardon, D.4    Olive, D.5    Gaugler, B.6
  • 116
    • 0023874728 scopus 로고
    • Tumour necrosis factor- in murine autoimmune 'lupus' nephritis
    • Jacob C. O., McDevitt H. O., Tumour necrosis factor- in murine autoimmune 'lupus' nephritis Nature 1988 331 6154 356 358
    • (1988) Nature , vol.331 , Issue.6154 , pp. 356-358
    • Jacob, C.O.1    McDevitt, H.O.2
  • 117
    • 49349116377 scopus 로고    scopus 로고
    • The role of CD4 + CD25 + T regulatory cells in autoimmune diseases
    • Toubi E., The role of CD4 + CD25 + T regulatory cells in autoimmune diseases Clinical Reviews in Allergy and Immunology 2008 34 3 338 344
    • (2008) Clinical Reviews in Allergy and Immunology , vol.34 , Issue.3 , pp. 338-344
    • Toubi, E.1
  • 119
    • 26244454545 scopus 로고    scopus 로고
    • Elimination of CD4 + CD25 + T cell accelerates the development of glomerulonephritis during the preactive phase in autoimmune-prone female NZB NZWF 1 mice
    • Hayashi T., Hasegawa K., Adachi C., Elimination of CD4 + CD25 + T cell accelerates the development of glomerulonephritis during the preactive phase in autoimmune-prone female NZB NZWF 1 mice International Journal of Experimental Pathology 2005 86 5 289 296
    • (2005) International Journal of Experimental Pathology , vol.86 , Issue.5 , pp. 289-296
    • Hayashi, T.1    Hasegawa, K.2    Adachi, C.3
  • 120
    • 58449114077 scopus 로고    scopus 로고
    • Systemic treatment of anti-CD4 + CD25 + T cell monoclonal antibody exacerbates sialoadenitis in submandibular glands during the early life in lupus-prone female NZB NZWF 1 mice
    • Hayashi T., Adachi C., Hasegawa K., Systemic treatment of anti-CD4 + CD25 + T cell monoclonal antibody exacerbates sialoadenitis in submandibular glands during the early life in lupus-prone female NZB NZWF 1 mice Journal of Oral Pathology and Medicine 2009 38 2 234 240
    • (2009) Journal of Oral Pathology and Medicine , vol.38 , Issue.2 , pp. 234-240
    • Hayashi, T.1    Adachi, C.2    Hasegawa, K.3
  • 121
    • 33746214867 scopus 로고    scopus 로고
    • Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells
    • Scalapino K. J., Tang Q., Bluestone J. A., Bonyhadi M. L., Daikh D. I., Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells Journal of Immunology 2006 177 3 1451 1459
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1451-1459
    • Scalapino, K.J.1    Tang, Q.2    Bluestone, J.A.3    Bonyhadi, M.L.4    Daikh, D.I.5
  • 122
    • 23144450643 scopus 로고    scopus 로고
    • Regulatory T cells: Development, function and role in autoimmunity
    • Lan R. Y., Ansari A. A., Lian Z.-X., Gershwin M. E., Regulatory T cells: development, function and role in autoimmunity Autoimmunity Reviews 2005 4 6 351 363
    • (2005) Autoimmunity Reviews , vol.4 , Issue.6 , pp. 351-363
    • Lan, R.Y.1    Ansari, A.A.2    Lian, Z.-X.3    Gershwin, M.E.4
  • 124
    • 1242267910 scopus 로고    scopus 로고
    • CD4 + and CD8 + regulatory T cells generated ex vivo with IL-2 and TGF- suppress a stimulatory graft-versus-host disease with a lupus-like syndrome
    • Zheng S. G., Wang J. H., Koss M. N., Quismorio F. Jr., Gray J. D., Horwitz D. A., CD4 + and CD8 + regulatory T cells generated ex vivo with IL-2 and TGF- suppress a stimulatory graft-versus-host disease with a lupus-like syndrome Journal of Immunology 2004 172 3 1531 1539
    • (2004) Journal of Immunology , vol.172 , Issue.3 , pp. 1531-1539
    • Zheng, S.G.1    Wang, J.H.2    Koss, M.N.3    Quismorio Jr., F.4    Gray, J.D.5    Horwitz, D.A.6
  • 125
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25 high Foxp3 pos regulatory T cells differentiate into IL-17 producing cells
    • Koenen H. J. P. M., Smeets R. L., Vink P. M., van Rijssen E., Boots A. M. H., Joosten I., Human CD25 high Foxp3 pos regulatory T cells differentiate into IL-17 producing cells Blood 2008 112 6 2340 2352
    • (2008) Blood , vol.112 , Issue.6 , pp. 2340-2352
    • Koenen, H.J.P.M.1    Smeets, R.L.2    Vink, P.M.3    Van Rijssen, E.4    Boots, A.M.H.5    Joosten, I.6
  • 126
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells induce CD4 + CD25 - Foxp3 - T cells or are self-induced to become Th17 cells in the absence of exogenous TGF
    • Xu L., Kitani A., Fuss I., Strober W., Cutting edge: regulatory T cells induce CD4 + CD25 - Foxp3 - T cells or are self-induced to become Th17 cells in the absence of exogenous TGF- Journal of Immunology 2007 178 11 6725 6729
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 129
    • 44449140087 scopus 로고    scopus 로고
    • Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4 + self-reactive T cells
    • Terme M., Chaput N., Combadiere B., Averil M., Ohteki T., Zitvogel L., Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4 + self-reactive T cells Journal of Immunology 2008 180 7 4679 4686
    • (2008) Journal of Immunology , vol.180 , Issue.7 , pp. 4679-4686
    • Terme, M.1    Chaput, N.2    Combadiere, B.3    Averil, M.4    Ohteki, T.5    Zitvogel, L.6
  • 130
    • 33646567156 scopus 로고    scopus 로고
    • Activated CD4 + CD25 + T cells selectively kill B lymphocytes
    • Zhao D.-M., Thornton A. M., DiPaolo R. J., Shevach E. M., Activated CD4 + CD25 + T cells selectively kill B lymphocytes Blood 2006 107 10 3925 3932
    • (2006) Blood , vol.107 , Issue.10 , pp. 3925-3932
    • Zhao, D.-M.1    Thornton, A.M.2    Dipaolo, R.J.3    Shevach, E.M.4
  • 131
    • 41949087565 scopus 로고    scopus 로고
    • T regulatory cells control numbers of NK cells and CD8 + immature dendritic cells in the lymph node paracortex
    • Giroux M., Yurchenko E., St-Pierre J., Piccirillo C. A., Perreault C., T regulatory cells control numbers of NK cells and CD8 + immature dendritic cells in the lymph node paracortex Journal of Immunology 2007 179 7 4492 4502
    • (2007) Journal of Immunology , vol.179 , Issue.7 , pp. 4492-4502
    • Giroux, M.1    Yurchenko, E.2    St-Pierre, J.3    Piccirillo, C.A.4    Perreault, C.5
  • 133
    • 76949084636 scopus 로고    scopus 로고
    • Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage
    • Cai Y., Rodriguez S., Rameswaran R., Draghia-Akli R., Juba R. J. Jr., Hebel H., Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage Vaccine 2010 28 8 2046 2052
    • (2010) Vaccine , vol.28 , Issue.8 , pp. 2046-2052
    • Cai, Y.1    Rodriguez, S.2    Rameswaran, R.3    Draghia-Akli, R.4    Juba Jr., R.J.5    Hebel, H.6
  • 134
    • 34548558680 scopus 로고    scopus 로고
    • Production of plasmid DNA for pharmaceutical use
    • Voss C., Production of plasmid DNA for pharmaceutical use Biotechnology Annual Review 2007 13 201 222
    • (2007) Biotechnology Annual Review , vol.13 , pp. 201-222
    • Voss, C.1
  • 135
    • 34249942373 scopus 로고    scopus 로고
    • Production of clinical-grade plasmid DNA for human Phase i clinical trials and large animal clinical studies
    • Przybylowski M., Bartido S., Borquez-Ojeda O., Sadelain M., Rivire I., Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies Vaccine 2007 25 27 5013 5024
    • (2007) Vaccine , vol.25 , Issue.27 , pp. 5013-5024
    • Przybylowski, M.1    Bartido, S.2    Borquez-Ojeda, O.3    Sadelain, M.4    Rivire, I.5
  • 137
    • 0026922764 scopus 로고
    • Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle
    • Wolff J. A., Ludtke J. J., Acsadi G., Williams P., Jani A., Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle Human Molecular Genetics 1992 1 6 363 369
    • (1992) Human Molecular Genetics , vol.1 , Issue.6 , pp. 363-369
    • Wolff, J.A.1    Ludtke, J.J.2    Acsadi, G.3    Williams, P.4    Jani, A.5
  • 138
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • Wolff J. A., Malone R. W., Williams P., Direct gene transfer into mouse muscle in vivo Science 1990 247 4949 1465 1468
    • (1990) Science , vol.247 , Issue.4949 , pp. 1465-1468
    • Wolff, J.A.1    Malone, R.W.2    Williams, P.3
  • 139
    • 19144364120 scopus 로고    scopus 로고
    • Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis
    • Evans C. H., Robbins P. D., Ghivizzani S. C., Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis Human Gene Therapy 1996 7 10 1261 1280
    • (1996) Human Gene Therapy , vol.7 , Issue.10 , pp. 1261-1280
    • Evans, C.H.1    Robbins, P.D.2    Ghivizzani, S.C.3
  • 142
    • 0027713222 scopus 로고
    • Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle
    • Davis H. L., Demeneix B. A., Quantin B., Coulombe J., Whalen R. G., Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle Human Gene Therapy 1993 4 6 733 740
    • (1993) Human Gene Therapy , vol.4 , Issue.6 , pp. 733-740
    • Davis, H.L.1    Demeneix, B.A.2    Quantin, B.3    Coulombe, J.4    Whalen, R.G.5
  • 144
    • 0034968841 scopus 로고    scopus 로고
    • Possible involvement of IL-12 in reovirus type-2-induced diabetes in newborn DBA/1 mice
    • Hayashi T., Morimoto M., Iwata H., Onodera T., Possible involvement of IL-12 in reovirus type-2-induced diabetes in newborn DBA/1 mice Scandinavian Journal of Immunology 2001 53 6 572 578
    • (2001) Scandinavian Journal of Immunology , vol.53 , Issue.6 , pp. 572-578
    • Hayashi, T.1    Morimoto, M.2    Iwata, H.3    Onodera, T.4
  • 145
    • 33646879417 scopus 로고    scopus 로고
    • What do mouse models teach us about human SLE?
    • Liu K., Mohan C., What do mouse models teach us about human SLE? Clinical Immunology 2006 119 2 123 130
    • (2006) Clinical Immunology , vol.119 , Issue.2 , pp. 123-130
    • Liu, K.1    Mohan, C.2


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