CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon γ

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 7, 1996, Pages 2879-2883

  Klinman, Dennis M ^a   Yi, Ae Kyung ^b   Beaucage, Serge L ^a   Conover, Jacqueline ^a   Krieg, Arthur M ^b  

^a Center for Biologics Evaluation/Res   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12 ANTIBODY; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIAL INFECTION; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFLAMMATION; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES; B-LYMPHOCYTES; BASE SEQUENCE; CELLS, CULTURED; DINUCLEOSIDE PHOSPHATES; DNA, BACTERIAL; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-6; KINETICS; LIPOPOLYSACCHARIDES; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; PHENOTYPE; SPLEEN; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTE SUBSETS; TIME FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); VERTEBRATA;

EID: 0029984358     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.7.2879     Document Type: Article

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