CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice

Life Sciences

Volumn 66, Issue 11, 2000, Pages 991-1001

  Takiguchi, Mitsuyoshi ^a,b   Murakami, Masaaki ^a   Nakagawa, Izumi ^a   Saito, Izumu ^c   Hashimoto, Akira ^b   Uede, Toshimitsu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adenovirus vector; CTLA4IgG; Gene therapy; Lupus; MRL lpr mice

Indexed keywords

AUTOANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN G;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; FEMALE; GENE TARGETING; GLOMERULONEPHRITIS; HISTOPATHOLOGY; HYPERGAMMAGLOBULINEMIA; KIDNEY FUNCTION TEST; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PROTEINURIA; SYSTEMIC LUPUS ERYTHEMATOSUS; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; AUTOANTIBODIES; FEMALE; GENE THERAPY; GENETIC VECTORS; IMMUNOCONJUGATES; KIDNEY FUNCTION TESTS; LUPUS NEPHRITIS; MICE; MICE, KNOCKOUT;

ADENOVIRIDAE; ANIMALIA;

EID: 0033976034     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(99)00664-5     Document Type: Article

References (41)

1. B.S. Andrews, R.A. Eisenberg, A.N. Theofilopoulos, S. Izui, C.B. Wilson, P.J. McConaheyc, E.D. Murphy, J.B. Roths and F.J. Dixon, J. Exp. Med. 148 1198-1215 (1978).
2. P.L. Cohen and R.A. Eisenberg, Annu. Rev. Immunol. 9 243-269 (1991).
3. A.N. Theofilopoulos and F.J. Dixon, Adv. Immunol. 37 269-390 (1985).
4. M. Adachi, R. Watanabe-Fukunaga and S. Nagata, Proc. Natl. Acad. Sci. USA. 90 1756-1760 (1993).
5. R. Watanabe-Fukunaga, C.I. Brannanb, N.G. Copeland, N.A. Jenkins and S. Nagata, Nature (Lond) 356 314-317 (1992).
6. J.L. Chu, J. Drappa, A. Parnassa and K.B. Elkon, J. Exp. Med. 178 723-730 (1993).
7. S. Kobayashi, T. Hirano, M. Kakinuma and T. Uede, Biochem. Biophys. Res. Commun. 191 617-624 (1993).
8. J. Wu, T. Zhou, J. He and J.D. Mountz, J. Exp. Med. 178 461-468 (1993).
9. J.H. Russel, B. Rush, C. Weaver and R. Wang, Proc. Natl. Acad. Sci. USA. 90 4409-4413 (1993).
10. G.G. Singer and A.K. Abbas, Immunity 1 365-371 (1994).
11. G.H. Fisher, F.J. Rosenberg, S.E. Straus, J.K. Dale, L.A. Middleton, A.Y. Lin, W. Strober, M.J. Lenardo and J.M. Puck, Cell 81 935-946 (1995).
12. T. Renno, M. Hahne, J. Tschopp and H.R. Macdonald, J. Exp. Med. 183 431-437 (1996).
13. L. Van Parijis, A. Ibraghimov and A.K. Abbas, Immunity 4 321-328 (1996).
14. H.C.I. Morse, W.F. Davidson, R.A. Yetter, E.D. Murphy, J.B. Roths and R.L. Coffman, J. Immunol. 129 2612-2615 (1982).
15. D. Wofsy, J.A. Ledbetter, P.L. Hendler and W.E. Seaman, J. Immunol. 134 852-857 (1985).
16. A.M. Jevnikar, M.J. Grusby and L.H. Glimcher, J. Exp. Med. 179 1137-1143 (1994).
17. D.R. Koh, A. Ho, A. Rahemtulla, W.P. Fung-Leung, H. Griesser and T.W. Mak, Eur. J. Immunol. 25 2558-2562 (1995).
18. S.L. Peng, M.P. Madaio, D.P.M. Hughes, I.N. Cripse, M.J. Owen, L. Wen, A.C. Hayday and J. Craft, J. Immunol. 156 4041-4049 (1996).
19. T.J. Santoro, J.P. Portanova and B.L. Kotzin, J. Exp. Med 167 1713-1718 (1988).
20. W.E. Seaman, D. Wofsy, J.S. Greenspan and J.A. Ledbetter, J. Immunol. 130 1713-1718 (1983).
21. J.A. Bluestone, Immunity 2 555-559 (1995).
22. P. Linsley and J. Ledbetter, Annu. Rev. Immunol. 11 191-212 (1993).
23. C. Thompson, Cell 81 979-982 (1995).
24. C.H. June, J.A. Bluestone, L.M. Nadler and C.B. Thompson, Immunol. Today 15 321-332 (1994).
25. J.P. Allison, Curr. Opin. Immunol. 6 414-419 (1994).
26. M.H. Sayegh and L.A. Turka, J. Am. Soc. Nephrol. 6 1143-1150 (1995).
27. P.S. Linsley, P.M. Wallace, J. Johnson, M.G. Gibson, J.L. Greene, J.A. Ledbetter, C. Singh and M.A. Tepper, Science 257 792-795 (1992).
28. E.B. Chu, M.V. Hobbs, C.B. Wilson, C.G. Romball, P.S. Linsley and W.O. Weigle, J. Immunol. 156 1262-1268 (1996).
29. B.K. Finck, P.S. Linsley and D. Wofsy, Science 265 1225-1227 (1994).
30. M. Takiguchi, M. Murakami, I. Nakagawa, A. Yamada, S. Chikuma, Y. Kawaguchi, A. Hashimoto and T. Uede, Lab. Invest. 79 317-326 (1999).
31. I. Nakagawa, M. Murakami, K. Ijima, S. Chikuma, I. Saito, Y. Kanagae, H. Ishikura, T. Yoshiki, H. Okamoto, A. Kitabatake and T. Uede, Hum. Gene Ther. 9 1739-1745. (1998).
32. H. Niwa, K. Yamamura and J. Miyazaki, Gene 108 193-200. (1991).
33. F.L. Graham and L. Prevec, Mol. Biotechnol. 3 207-220 (1995).
34. C.T. Ravirajan, C.E. Sarraf, T.V. Anilkumar, M.C. Golding, M.R. Alison and D.A. Isenberg, Clin. Exp. Immunol. 105 306-312 (1996).
35. M.L. Watson, J.K. Rao, G.S. Gilkeson, P. Ruiz, E.M. Eicher, D.S. Pisetsky, A. Matsuzawa, J.M. Rochelle and M.F. Seldin, J. Exp. Med. 176 1645-1656 (1992).
36. G.D. Schmidt-Wolf and I.G.H. Schmidt-Wolf, Immunol. Today 16 173-175 (1995).
37. P.M. Mathisen and V.K. Tuohy, Immunol. Today 19 103-105 (1998).
38. E. Raz, J. Dudler, M. Lotz, S.M. Baird, C.C. Berry, R.A. Eisenberg and D.A. Carson, Lupus 4 286-292 (1995).
39. M.L. Huggins, F.P. Huang, D. Xu, G. Lindop and D.I. Stott, Lupus 8 29-38 (1999).
40. S.L. Peng, J. Moslehi and J. Craft, J. Clin. Invest. 99 1936-1946 (1997).
41. Y. Yang, F.A. Nunes, K. Berencsi, E.E. Furth, E. Gonczol and J.M. Wilson, Proc. Natl. Acad. Sci. USA. 91 4407-4411 (1994).