Sustained prolonged topical delivery of bioactive human insulin for potential treatment of cutaneous wounds

International Journal of Pharmaceutics

Volumn 398, Issue 1-2, 2010, Pages 146-154

  Hrynyk, Michael ^a   Martins Green, Manuela ^b   Barron, Annelise E ^c   Neufeld, Ronald J ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Stanford University   (United States)

Author keywords

Controlled release; HaCaT; Insulin; L6 myoblasts; Microspheres; PLGA; Wound healing

Indexed keywords

MICROSPHERE; POLYGLACTIN; PROTEIN KINASE B; RECOMBINANT HUMAN INSULIN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; CRYSTAL; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KERATINOCYTE; MORPHOLOGY; MYOFIBROBLAST; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SKIN INJURY; SUSTAINED RELEASE FORMULATION; TRANSMISSION ELECTRON MICROSCOPY; WOUND HEALING;

ADMINISTRATION, CUTANEOUS; ANIMALS; CELL LINE; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; HUMANS; INSULIN; MICROSPHERES; MYOBLASTS; RATS; RECOMBINANT PROTEINS; TIME FACTORS; WOUND HEALING; WOUNDS AND INJURIES;

EID: 77956224955     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.052     Document Type: Article

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