Alginate microparticles as novel carrier for oral insulin delivery

Biotechnology and Bioengineering

Volumn 96, Issue 5, 2007, Pages 977-989

  Reis, Catarina Pinto ^a   Ribeiro, António J ^b   Neufeld, Ronald J ^c   Veiga, Francisco ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

Alginate; Emulsification internal gelation; Insulin; Microparticles; Recovery process

Indexed keywords

ALGINATES; INTERNAL GELATION; MICROPARTICLES; RECOVERY PROCESS; SECONDARY STRUCTURE;

ACETONE; CENTRIFUGATION; EMULSIFICATION; GELATION; INSULIN; PARTICLE SIZE; PROPANOL; PROTEINS;

DRUG DELIVERY;

2 PROPANOL; ACETONE; ALGINIC ACID; ALGOGEL 3541; CALCIUM ION; CARBONIC ACID; DRUG CARRIER; HEXANE; INSULIN; INSULINASE; UNCLASSIFIED DRUG;

ARTICLE; CENTRIFUGATION; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; EMULSION; ENCAPSULATION; GELATION; IN VITRO STUDY; INSULIN RELEASE; INTESTINE ABSORPTION; MASS SPECTROMETRY; PARTICLE SIZE; PH; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ADMINISTRATION, ORAL; ALGINATES; DRUG ADMINISTRATION ROUTES; DRUG DELIVERY SYSTEMS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; INSULIN; MICROSPHERES; PARTICLE SIZE;

EID: 33947610989     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21164     Document Type: Article

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