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Volumn 18, Issue 5, 2010, Pages 240-250

Treatment of anemia in heart failure: Potential risks and benefits of intravenous iron therapy in cardiovascular disease

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROCYTE PROTOPORPHYRIN; FERRIC HYDROXIDE SUCROSE; FERRITIN; HEMOGLOBIN; IRON; NITRIC OXIDE; TRANSFERRIN;

EID: 77955830245     PISSN: 10615377     EISSN: None     Source Type: Journal    
DOI: 10.1097/CRD.0b013e3181e71150     Document Type: Review
Times cited : (12)

References (124)
  • 1
    • 0037656519 scopus 로고    scopus 로고
    • Trace elements and host defense: Recent advances and continuing challenges
    • Failla ML. Trace elements and host defense: recent advances and continuing challenges. JNutr. 2003;133:1443S-1447S.
    • (2003) J Nutr , vol.133
    • Failla, M.L.1
  • 3
    • 0035153971 scopus 로고    scopus 로고
    • Iron biology in immune function, muscle metabolism and neuronal functioning
    • Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr. 2001;131:568S-579S.
    • (2001) J Nutr , vol.131
    • Beard, J.L.1
  • 5
    • 10844240718 scopus 로고    scopus 로고
    • "Pumping" iron: The proteins
    • Beutler E. Cell biology. "Pumping" iron: the proteins. Science. 2004;306: 2051-2053.
    • (2004) Science , vol.306 , pp. 2051-2053
    • Beutler, E.1    Biology, C.2
  • 6
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3
  • 7
    • 0041672570 scopus 로고    scopus 로고
    • Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
    • Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood. 2003;102:783-788.
    • (2003) Blood , vol.102 , pp. 783-788
    • Ganz, T.1
  • 8
    • 33646899011 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: Genetic complexity and new diagnostic approaches
    • Swinkels DW, Janssen MC, Bergmans J, et al. Hereditary hemochromatosis: genetic complexity and new diagnostic approaches. Clin Chem. 2006;52: 950-968.
    • (2006) Clin Chem , vol.52 , pp. 950-968
    • Swinkels, D.W.1    Janssen, M.C.2    Bergmans, J.3
  • 9
    • 33747167627 scopus 로고    scopus 로고
    • Detection of serum hepcidin in renal failure and inflammation by using ProteinChip System
    • Tomosugi N, Kawabata H, Wakatabe R, et al. Detection of serum hepcidin in renal failure and inflammation by using ProteinChip System. Blood. 2006;108:1381-1387.
    • (2006) Blood , vol.108 , pp. 1381-1387
    • Tomosugi, N.1    Kawabata, H.2    Wakatabe, R.3
  • 10
    • 41949133287 scopus 로고    scopus 로고
    • Iron regulation and erythropoiesis
    • Nemeth E. Iron regulation and erythropoiesis. Curr Opin Hematol. 2008; 15:169-175.
    • (2008) Curr Opin Hematol , vol.15 , pp. 169-175
    • Nemeth, E.1
  • 12
    • 7944222409 scopus 로고    scopus 로고
    • Iron, free radicals, and oxidative injury
    • McCord JM. Iron, free radicals, and oxidative injury. J Nutr. 2004;134: 3171S-3172S.
    • (2004) J Nutr , vol.134
    • McCord, J.M.1
  • 13
    • 10844282789 scopus 로고    scopus 로고
    • Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo
    • Meyron-Holtz EG, Ghosh MC, Rouault TA. Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo. Science. 2004;306: 2087-2090.
    • (2004) Science , vol.306 , pp. 2087-2090
    • Meyron-Holtz, E.G.1    Ghosh, M.C.2    Rouault, T.A.3
  • 14
    • 17944388628 scopus 로고    scopus 로고
    • Nature of nontransferrin-bound iron
    • Hider RC. Nature of nontransferrin-bound iron. Eur J Clin Invest. 2002; 32(suppl 1):50-54.
    • (2002) Eur J Clin Invest , vol.32 , Issue.SUPPL. 1 , pp. 50-54
    • Hider, R.C.1
  • 15
    • 0031567095 scopus 로고    scopus 로고
    • The molecular mechanisms ofthe metabolism and transport of iron in normal and neoplastic cells
    • Richardson DR, Ponka P. The molecular mechanisms ofthe metabolism and transport of iron in normal and neoplastic cells. Biochim Biophys Acta. 1997;1331:1-40.
    • (1997) Biochim Biophys Acta , vol.1331 , pp. 1-40
    • Richardson, D.R.1    Ponka, P.2
  • 16
    • 0032964289 scopus 로고    scopus 로고
    • Cellular iron metabolism
    • Ponka P. Cellular iron metabolism. Kidney Int Suppl. 1999;69:S2-S11.
    • (1999) Kidney Int Suppl , vol.69
    • Ponka, P.1
  • 17
    • 0037409871 scopus 로고    scopus 로고
    • Calcein as a fluorescent iron chemosensor for the determination of low molecular weight iron in biological fluids
    • Ali A, Zhang Q, Dai J, et al. Calcein as a fluorescent iron chemosensor for the determination of low molecular weight iron in biological fluids. Biomet-als. 2003;16:285-293.
    • (2003) Biomet-als , vol.16 , pp. 285-293
    • Ali, A.1    Zhang, Q.2    Dai, J.3
  • 18
    • 0033677772 scopus 로고    scopus 로고
    • The importance of non-transferrin bound iron in disorders of iron metabolism
    • Breuer W, Hershko C, Cabantchik ZI. The importance of non-transferrin bound iron in disorders of iron metabolism. Transfus Sci. 2000;23:185-192.
    • (2000) Transfus Sci , vol.23 , pp. 185-192
    • Breuer, W.1    Hershko, C.2    Cabantchik, Z.I.3
  • 19
    • 0002371305 scopus 로고    scopus 로고
    • Clinical consequences of new insights in the pathophysiology of disorders of iron and heme metabolism
    • Brittenham GM, Weiss G, Brissot P, et al. Clinical consequences of new insights in the pathophysiology of disorders of iron and heme metabolism. Hematol Am Soc Hematol Educ Program. 2000:39-50.
    • (2000) Hematol Am Soc Hematol Educ Program , pp. 39-50
    • Brittenham, G.M.1    Weiss, G.2    Brissot, P.3
  • 20
    • 0036086314 scopus 로고    scopus 로고
    • Physiology of iron transport and the hemochromatosis gene
    • Pietrangelo A. Physiology of iron transport and the hemochromatosis gene. Am J Physiol Gastrointest Liver Physiol. 2002;282:G403-G414.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282
    • Pietrangelo, A.1
  • 21
    • 0033599057 scopus 로고    scopus 로고
    • Disorders of iron metabolism
    • Andrews NC. Disorders of iron metabolism. NEnglJMed. 1999;341:1986-1995.
    • (1999) NEnglJMed , vol.341 , pp. 1986-1995
    • Andrews, N.C.1
  • 22
    • 0035117302 scopus 로고    scopus 로고
    • Iron status of free-living elderly individuals
    • Beard J. Iron status of free-living elderly individuals. Am J Clin Nutr. 2001;73:503-504.
    • (2001) Am J Clin Nutr , vol.73 , pp. 503-504
    • Beard, J.1
  • 23
    • 0035058978 scopus 로고    scopus 로고
    • A bone marrow report of absent stainable iron is not diagnostic of iron deficiency
    • Barron BA, Hoyer JD, Tefferi A. A bone marrow report of absent stainable iron is not diagnostic of iron deficiency. Ann Hematol. 2001;80:166-169.
    • (2001) Ann Hematol , vol.80 , pp. 166-169
    • Barron, B.A.1    Hoyer, J.D.2    Tefferi, A.3
  • 24
    • 15444348944 scopus 로고
    • Anemias
    • Paige DM, ed. St. Louis, CV: Mosby
    • Herbert V. Anemias. In: Paige DM, ed. Clinical Nutrition. St. Louis, CV: Mosby; 1988:593.
    • (1988) Clinical Nutrition , vol.593
    • Herbert, V.1
  • 25
    • 0037024202 scopus 로고    scopus 로고
    • Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure
    • Horwich TB, Fonarow GC, Hamilton MA, et al. Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J Am Coll Cardiol. 2002;39:1780-1786.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1780-1786
    • Horwich, T.B.1    Fonarow, G.C.2    Hamilton, M.A.3
  • 26
    • 0043011312 scopus 로고    scopus 로고
    • Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure
    • Felker GM, Gattis WA, Leimberger JD, et al. Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure. Am J Cardiol. 2003;92:625-628.
    • (2003) Am J Cardiol , vol.92 , pp. 625-628
    • Felker, G.M.1    Gattis, W.A.2    Leimberger, J.D.3
  • 27
    • 0037976873 scopus 로고    scopus 로고
    • Anemia predicts mortality in severe heart failure: The prospective randomized amlodipine survival evaluation (PRAISE)
    • Mozaffarian D, Nye R, Levy WC. Anemia predicts mortality in severe heart failure: the prospective randomized amlodipine survival evaluation (PRAISE). JAm Coll Cardiol. 2003;41:1933-1939.
    • (2003) JAm Coll Cardiol , vol.41 , pp. 1933-1939
    • Mozaffarian, D.1    Nye, R.2    Levy, W.C.3
  • 28
    • 0037313797 scopus 로고    scopus 로고
    • The prognostic importance of anemia in patients with heart failure
    • Kosiborod M, Smith GL, Radford MJ, et al. The prognostic importance of anemia in patients with heart failure. Am J Med. 2003;114:112-119.
    • (2003) Am J Med , vol.114 , pp. 112-119
    • Kosiborod, M.1    Smith, G.L.2    Radford, M.J.3
  • 29
    • 0036831245 scopus 로고    scopus 로고
    • The prevalence of anemia in chronic heart failure
    • Tanner H, Moschovitis G, Kuster GM, et al. The prevalence of anemia in chronic heart failure. Int J Cardiol 2002;86:115-121.
    • (2002) Int J Cardiol , vol.86 , pp. 115-121
    • Tanner, H.1    Moschovitis, G.2    Kuster, G.M.3
  • 30
    • 0036215706 scopus 로고    scopus 로고
    • Anaemia in chronic heart failure: What is its frequency in the UK and its underlying causes?
    • Cromie N, Lee C, Struthers AD. Anaemia in chronic heart failure: what is its frequency in the UK and its underlying causes? Heart. 2002;87: 377-378.
    • (2002) Heart , vol.87 , pp. 377-378
    • Cromie, N.1    Lee, C.2    Struthers, A.D.3
  • 31
    • 0037458095 scopus 로고    scopus 로고
    • Anemia is common in heart failure and is associated with poor outcomes: Insights from a cohort of 12 065 patients with new-onset heart failure
    • Ezekowitz JA, McAlister FA, Armstrong PW. Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12 065 patients with new-onset heart failure. Circulation. 2003;107:223-225.
    • (2003) Circulation , vol.107 , pp. 223-225
    • Ezekowitz, J.A.1    McAlister, F.A.2    Armstrong, P.W.3
  • 32
    • 0037378082 scopus 로고    scopus 로고
    • Effect of anemia on exercise tolerance in chronic heart failure in men
    • Kalra PR, Bolger AP, Francis DP, et al. Effect of anemia on exercise tolerance in chronic heart failure in men. Am J Cardiol. 2003;91:888-891.
    • (2003) Am J Cardiol , vol.91 , pp. 888-891
    • Kalra, P.R.1    Bolger, A.P.2    Francis, D.P.3
  • 33
    • 0038378702 scopus 로고    scopus 로고
    • Anaemia is an independent predictor of poor outcome in patients with chronic heart failure
    • Szachniewicz J, Petruk-Kowalczyk J, Majda J, et al. Anaemia is an independent predictor of poor outcome in patients with chronic heart failure. Int J Cardiol. 2003;90:303-308.
    • (2003) Int J Cardiol , vol.90 , pp. 303-308
    • Szachniewicz, J.1    Petruk-Kowalczyk, J.2    Majda, J.3
  • 34
    • 3142688226 scopus 로고    scopus 로고
    • Anemia and its relationship to clinical outcome in heart failure
    • Anand I, McMurray JJ, Whitmore J, et al. Anemia and its relationship to clinical outcome in heart failure. Circulation. 2004;110:149-154.
    • (2004) Circulation , vol.110 , pp. 149-154
    • Anand, I.1    McMurray, J.J.2    Whitmore, J.3
  • 35
    • 0036896347 scopus 로고    scopus 로고
    • The importance of anemia and its correction in the management of severe congestive heart failure
    • Silverberg DS, Wexler D, Iaina A. The importance of anemia and its correction in the management of severe congestive heart failure. Eur J Heart Fail. 2002;4:681-686.
    • (2002) Eur J Heart Fail , vol.4 , pp. 681-686
    • Silverberg, D.S.1    Wexler, D.2    Iaina, A.3
  • 36
    • 0036308047 scopus 로고    scopus 로고
    • Pathogenesis and treatment of anaemia of chronic disease
    • Weiss G. Pathogenesis and treatment of anaemia of chronic disease. Blood Rev. 2002;16:87-96.
    • (2002) Blood Rev , vol.16 , pp. 87-96
    • Weiss, G.1
  • 37
    • 0034897735 scopus 로고    scopus 로고
    • Acquired growth hormone resistance in patients with chronic heart failure: Implications for therapy with growth hormone
    • Anker SD, Volterrani M, Pflaum CD, et al. Acquired growth hormone resistance in patients with chronic heart failure: implications for therapy with growth hormone. J Am Coll Cardiol. 2001;38:443-452.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 443-452
    • Anker, S.D.1    Volterrani, M.2    Pflaum, C.D.3
  • 38
    • 0032945406 scopus 로고    scopus 로고
    • An overview of tumor necrosis factor alpha and the failing human heart
    • Torre-Amione G, Bozkurt B, Deswal A, et al. An overview of tumor necrosis factor alpha and the failing human heart. Curr Opin Cardiol. 1999;14:206-210.
    • (1999) Curr Opin Cardiol , vol.14 , pp. 206-210
    • Torre-Amione, G.1    Bozkurt, B.2    Deswal, A.3
  • 39
    • 0036348143 scopus 로고    scopus 로고
    • Cytokines, apoptosis and cachexia: The potential for TNF antagonism
    • Sharma R, Anker SD. Cytokines, apoptosis and cachexia: the potential for TNF antagonism. Int J Cardiol. 2002;85:161-171.
    • (2002) Int J Cardiol , vol.85 , pp. 161-171
    • Sharma, R.1    Anker, S.D.2
  • 40
    • 0037134841 scopus 로고    scopus 로고
    • The regulation and measurement of plasma volume in heart failure
    • Kalra PR, Anagnostopoulos C, Bolger AP, et al. The regulation and measurement of plasma volume in heart failure. J Am Coll Cardiol. 2002; 39:1901-1908.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1901-1908
    • Kalra, P.R.1    Anagnostopoulos, C.2    Bolger, A.P.3
  • 41
    • 0027495285 scopus 로고
    • Pathogenesis of oedema in chronic severe anaemia: Studies of body water and sodium, renal function, haemodynamic variables, and plasma hormones
    • Anand IS, Chandrashekhar Y, Ferrari R, et al. Pathogenesis of oedema in chronic severe anaemia: studies of body water and sodium, renal function, haemodynamic variables, and plasma hormones. Br Heart J. 1993;70:357-362.
    • (1993) Br Heart J , vol.70 , pp. 357-362
    • Anand, I.S.1    Chandrashekhar, Y.2    Ferrari, R.3
  • 43
    • 0034961664 scopus 로고    scopus 로고
    • Angiotensin II infusion increases plasma erythropoietin levels via an angiotensin II type 1 receptor-dependent pathway
    • Gossmann J, Burkhardt R, Harder S, et al. Angiotensin II infusion increases plasma erythropoietin levels via an angiotensin II type 1 receptor-dependent pathway. Kidney Int. 2001;60:83-86.
    • (2001) Kidney Int , vol.60 , pp. 83-86
    • Gossmann, J.1    Burkhardt, R.2    Harder, S.3
  • 44
    • 0026796044 scopus 로고
    • Effect of angiotensin converting enzyme inhibitors on erythropoietin concentrations in healthy volunteers
    • Pratt MC, Lewis-Barned NJ, Walker RJ, et al. Effect of angiotensin converting enzyme inhibitors on erythropoietin concentrations in healthy volunteers. Br J Clin Pharmacol. 1992;34:363-365.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 363-365
    • Pratt, M.C.1    Lewis-Barned, N.J.2    Walker, R.J.3
  • 45
    • 0034530758 scopus 로고    scopus 로고
    • Serum erythropoietin in heart failure patients treated with ACE-inhibitors or AT(1) antagonists
    • Chatterjee B, Nydegger UE, Mohacsi P. Serum erythropoietin in heart failure patients treated with ACE-inhibitors or AT(1) antagonists. Eur J Heart Fail. 2000;2:393-398.
    • (2000) Eur J Heart Fail , vol.2 , pp. 393-398
    • Chatterjee, B.1    Nydegger, U.E.2    Mohacsi, P.3
  • 46
    • 13244268473 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction
    • Ishani A, Weinhandl E, Zhao Z, et al. Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction. JAm Coll Cardiol. 2005;45:391-399.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 391-399
    • Ishani, A.1    Weinhandl, E.2    Zhao, Z.3
  • 47
    • 33845299533 scopus 로고    scopus 로고
    • Etiology of anemia in patients with advanced heart failure
    • Nanas JN, Matsouka C, Karageorgopoulos D, et al. Etiology of anemia in patients with advanced heart failure. J Am Coll Cardiol. 2006;48:2485-2489.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2485-2489
    • Nanas, J.N.1    Matsouka, C.2    Karageorgopoulos, D.3
  • 48
    • 3042730052 scopus 로고    scopus 로고
    • Are hematinic deficiencies the cause of anemia in chronic heart failure?
    • Witte KK, Desilva R, Chattopadhyay S, et al. Are hematinic deficiencies the cause of anemia in chronic heart failure? Am Heart J. 2004;147:924-930.
    • (2004) Am Heart J , vol.147 , pp. 924-930
    • Witte, K.K.1    Desilva, R.2    Chattopadhyay, S.3
  • 49
    • 34249813118 scopus 로고    scopus 로고
    • Is anemia in chronic heart failure caused by iron deficiency?
    • author reply 2302
    • Westenbrink BD, Voors AA, van Veldhuisen DJ. Is anemia in chronic heart failure caused by iron deficiency? J Am Coll Cardiol. 2007;49:2301-2302; author reply 2302.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2301-2302
    • Westenbrink, B.D.1    Voors, A.A.2    Van Veldhuisen, D.J.3
  • 50
    • 33744996445 scopus 로고    scopus 로고
    • The prevalence, nature, and importance of hematologic abnormalities in heart failure
    • Berry C, Norrie J, Hogg K, et al. The prevalence, nature, and importance of hematologic abnormalities in heart failure. Am Heart J. 2006;151:1313-1321.
    • (2006) Am Heart J , vol.151 , pp. 1313-1321
    • Berry, C.1    Norrie, J.2    Hogg, K.3
  • 51
    • 0028356323 scopus 로고
    • Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation
    • Katz SD, Rao R, Berman JW, et al. Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation. Circulation. 1994;90:12-16.
    • (1994) Circulation , vol.90 , pp. 12-16
    • Katz, S.D.1    Rao, R.2    Berman, J.W.3
  • 52
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B, Kalman J, Mayer L, et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med. 1990;323: 236-241.
    • (1990) N Engl J Med , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3
  • 53
    • 33744477631 scopus 로고    scopus 로고
    • Anemia in chronic heart failure: Prevalence, etiology, clinical correlates, and treatment options
    • Tang YD, Katz SD. Anemia in chronic heart failure: prevalence, etiology, clinical correlates, and treatment options. Circulation. 2006;113:2454-2461.
    • (2006) Circulation , vol.113 , pp. 2454-2461
    • Tang, Y.D.1    Katz, S.D.2
  • 54
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352:1011-1023.
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 55
    • 0037926880 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of iron transport in human monocytic cells
    • Ludwiczek S, Aigner E, Theurl I, et al. Cytokine-mediated regulation of iron transport in human monocytic cells. Blood. 2003;101:4148-4154.
    • (2003) Blood , vol.101 , pp. 4148-4154
    • Ludwiczek, S.1    Aigner, E.2    Theurl, I.3
  • 56
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271-1276.
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3
  • 57
    • 33748438999 scopus 로고    scopus 로고
    • Intravenous iron alone for the treatment of anemia in patients with chronic heart failure
    • Bolger AP, Bartlett FR, Penston HS, et al. Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. J Am Coll Cardiol. 2006;48:1225-1227.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1225-1227
    • Bolger, A.P.1    Bartlett, F.R.2    Penston, H.S.3
  • 58
    • 35248870765 scopus 로고    scopus 로고
    • Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency
    • Toblli JE, Lombrana A, Duarte P, et al. Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. JAm Coll Cardiol. 2007;50:1657-1665.
    • (2007) JAm Coll Cardiol , vol.50 , pp. 1657-1665
    • Toblli, J.E.1    Lombrana, A.2    Duarte, P.3
  • 59
    • 37849053243 scopus 로고    scopus 로고
    • Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: A randomized, controlled, observer-blinded trial
    • Okonko DO, Grzeslo A, Witkowski T, et al. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. J Am Coll Cardiol. 2008;51: 103-112.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 103-112
    • Okonko, D.O.1    Grzeslo, A.2    Witkowski, T.3
  • 60
    • 50049102529 scopus 로고    scopus 로고
    • Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency
    • Usmanov RI, Zueva EB, Silverberg DS, et al. Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency. J Nephrol. 2008;21:236-242.
    • (2008) J Nephrol , vol.21 , pp. 236-242
    • Usmanov, R.I.1    Zueva, E.B.2    Silverberg, D.S.3
  • 61
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, Comin CJ, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. NEngl J Med. 2009;361:2436-2448.
    • (2009) N Engl J Med , vol.361 , pp. 2436-2448
    • Anker, S.D.1    Comin, C.J.2    Filippatos, G.3
  • 62
    • 0037458127 scopus 로고    scopus 로고
    • Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure
    • Mancini DM, Katz SD, Lang CC, et al. Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure. Circulation. 2003;107:294-299.
    • (2003) Circulation , vol.107 , pp. 294-299
    • Mancini, D.M.1    Katz, S.D.2    Lang, C.C.3
  • 63
    • 0036520829 scopus 로고    scopus 로고
    • Peripheral limitations of maximal aerobic capacity in patients with chronic heart failure
    • Katz SD, Zheng H. Peripheral limitations of maximal aerobic capacity in patients with chronic heart failure. J Nucl Cardiol. 2002;9:215-225.
    • (2002) J Nucl Cardiol , vol.9 , pp. 215-225
    • Katz, S.D.1    Zheng, H.2
  • 64
    • 0029930904 scopus 로고    scopus 로고
    • Iron-sulfur clusters as biosensors of oxidants and iron
    • Rouault TA, Klausner RD. Iron-sulfur clusters as biosensors of oxidants and iron. Trends Biochem Sci. 1996;21:174-177.
    • (1996) Trends Biochem Sci , vol.21 , pp. 174-177
    • Rouault, T.A.1    Klausner, R.D.2
  • 65
    • 0035150473 scopus 로고    scopus 로고
    • Iron deficiency and reduced work capacity: A critical review of the research to determine a causal relationship
    • discussion 688S-690S
    • Haas JD, Brownlie TT. Iron deficiency and reduced work capacity: a critical review of the research to determine a causal relationship. J Nutr. 2001;131: 676S-688S; discussion 688S-690S.
    • (2001) J Nutr , vol.131
    • Haas, J.D.1    Brownlie, T.T.2
  • 66
    • 0017074814 scopus 로고
    • Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction
    • Finch CA, Miller LR, Inamdar AR, et al. Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction. J Clin Invest. 1976;58:447-453.
    • (1976) J Clin Invest , vol.58 , pp. 447-453
    • Finch, C.A.1    Miller, L.R.2    Inamdar, A.R.3
  • 67
    • 0242691880 scopus 로고
    • Muscle mitochondrial bioener-getics, oxygen supply, and work capacity during dietary iron deficiency and repletion
    • Davies KJ, Maguire JJ, Brooks GA, et al. Muscle mitochondrial bioener-getics, oxygen supply, and work capacity during dietary iron deficiency and repletion. Am J Physiol. 1982;242:E418-E427.
    • (1982) Am J Physiol , vol.242
    • Davies, K.J.1    Maguire, J.J.2    Brooks, G.A.3
  • 68
    • 0021449954 scopus 로고
    • Distinguishing effects of anemia and muscle iron deficiency on exercise bioenergetics in the rat
    • Davies KJ, Donovan CM, Refino CJ, et al. Distinguishing effects of anemia and muscle iron deficiency on exercise bioenergetics in the rat. Am J Physiol. 1984;246:E535-E543
    • (1984) Am J Physiol , vol.246
    • Davies, K.J.1    Donovan, C.M.2    Refino, C.J.3
  • 69
    • 0025273204 scopus 로고
    • Iron deficiency: Improved exercise performance within 15 hours of iron treatment in rats
    • Willis WT, Gohil K, Brooks GA, et al. Iron deficiency: improved exercise performance within 15 hours of iron treatment in rats. J Nutr. 1990;120: 909-916.
    • (1990) J Nutr. , vol.120 , pp. 909-916
    • Willis, W.T.1    Gohil, K.2    Brooks, G.A.3
  • 70
    • 0022115191 scopus 로고
    • Work performance in the iron-deficient rat: Improved endurance with exercise training
    • Perkkio MV, Jansson LT, Henderson S, et al. Work performance in the iron-deficient rat: improved endurance with exercise training. Am J Physiol. 1985;249:E306-E311.
    • (1985) Am J Physiol , vol.249
    • Perkkio, M.V.1    Jansson, L.T.2    Henderson, S.3
  • 71
    • 0019595556 scopus 로고
    • Physiological and biochemical effects of iron deficiency on rat skeletal muscle
    • McLane JA, Fell RD, McKay RH, et al. Physiological and biochemical effects of iron deficiency on rat skeletal muscle. Am J Physiol. 1981;241: C47-C54.
    • (1981) Am J Physiol , vol.241
    • McLane, J.A.1    Fell, R.D.2    McKay, R.H.3
  • 72
    • 0037304555 scopus 로고    scopus 로고
    • Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women
    • Brutsaert TD, Hernandez-Cordero S, Rivera J, et al. Iron supplementation improves progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women. Am J Clin Nutr. 2003;77:441-448.
    • (2003) Am J Clin Nutr , vol.77 , pp. 441-448
    • Brutsaert, T.D.1    Hernandez-Cordero, S.2    Rivera, J.3
  • 73
    • 0036201255 scopus 로고    scopus 로고
    • Marginal iron deficiency without anemia impairs aerobic adaptation among previously untrained women
    • Brownlie T IV, Utermohlen V, Hinton PS, et al. Marginal iron deficiency without anemia impairs aerobic adaptation among previously untrained women. Am J Clin Nutr. 2002;75:734-742.
    • (2002) Am J Clin Nutr , vol.75 , pp. 734-742
    • Brownlie, T.I.V.1    Utermohlen, V.2    Hinton, P.S.3
  • 74
    • 1642393242 scopus 로고    scopus 로고
    • Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women
    • Brownlie Tt, Utermohlen V, Hinton PS, et al. Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr. 2004;79:437-443.
    • (2004) Am J Clin Nutr , vol.79 , pp. 437-443
    • Tt, B.1    Utermohlen, V.2    Hinton, P.S.3
  • 75
    • 0034093437 scopus 로고    scopus 로고
    • Iron supplementation improves endurance after training in iron-depleted, nonanemic women
    • Hinton PS, Giordano C, Brownlie T, et al. Iron supplementation improves endurance after training in iron-depleted, nonanemic women. J Appl Physiol. 2000;88:1103-1111.
    • (2000) J Appl Physiol , vol.88 , pp. 1103-1111
    • Hinton, P.S.1    Giordano, C.2    Brownlie, T.3
  • 76
    • 67649846460 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of iron supplementation in female soldiers during military training: Effects on iron status, physical performance, and mood
    • McClung JP, Karl JP, Cable SJ, et al. Randomized, double-blind, placebo-controlled trial of iron supplementation in female soldiers during military training: effects on iron status, physical performance, and mood. Am J Clin Nutr. 2009;90:124-131.
    • (2009) Am J Clin Nutr , vol.90 , pp. 124-131
    • McClung, J.P.1    Karl, J.P.2    Cable, S.J.3
  • 77
    • 54849163400 scopus 로고    scopus 로고
    • Iron involvement in multiple signaling pathways of atherosclerosis: A revisited hypothesis
    • Yuan XM, Li W. Iron involvement in multiple signaling pathways of atherosclerosis: a revisited hypothesis. Curr Med Chem. 2008;15:2157-2172.
    • (2008) Curr Med Chem , vol.15 , pp. 2157-2172
    • Yuan, X.M.1    Li, W.2
  • 78
    • 10944231116 scopus 로고    scopus 로고
    • Is stored iron safe?
    • Sullivan JL. Is stored iron safe? J Lab Clin Med. 2004;144:280-284.
    • (2004) J Lab Clin Med , vol.144 , pp. 280-284
    • Sullivan, J.L.1
  • 79
    • 0033537671 scopus 로고    scopus 로고
    • Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice
    • Lee TS, Shiao MS, Pan CC, et al. Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice. Circulation. 1999;99:1222-1229.
    • (1999) Circulation , vol.99 , pp. 1222-1229
    • Lee, T.S.1    Shiao, M.S.2    Pan, C.C.3
  • 80
    • 0036291430 scopus 로고    scopus 로고
    • Effect of iron depletion on cardiovascular risk factors: Studies in carbohydrate-intolerant patients
    • Facchini FS, Saylor KL. Effect of iron depletion on cardiovascular risk factors: studies in carbohydrate-intolerant patients. Ann N Y Acad Sci. 2002;967:342-351.
    • (2002) Ann N y Acad Sci , vol.967 , pp. 342-351
    • Facchini, F.S.1    Saylor, K.L.2
  • 81
    • 0041421288 scopus 로고    scopus 로고
    • Dietary iron restriction increases plaque stability in apolipoprotein-e-deficient mice
    • Lee HT, Chiu LL, Lee TS, et al. Dietary iron restriction increases plaque stability in apolipoprotein-e-deficient mice. JBiomedSci. 2003;10:510-517.
    • (2003) J Biomed Sci , vol.10 , pp. 510-517
    • Lee, H.T.1    Chiu, L.L.2    Lee, T.S.3
  • 82
    • 0025057335 scopus 로고
    • Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains
    • discussion 227-228
    • Patt A, Horesh IR, Berger EM, et al. Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains. JPediatr Surg. 1990; 25:224-227; discussion 227-228.
    • (1990) J Pediatr Surg , vol.25 , pp. 224-227
    • Patt, A.1    Horesh, I.R.2    Berger, E.M.3
  • 83
    • 0032829129 scopus 로고    scopus 로고
    • The onset of atherosclerotic lesion formation in hypercholesterolemic rabbits is delayed by iron depletion
    • Ponraj D, Makjanic J, Thong PS, et al. The onset of atherosclerotic lesion formation in hypercholesterolemic rabbits is delayed by iron depletion. FEBSLett. 1999;459:218-222.
    • (1999) FEBSLett , vol.459 , pp. 218-222
    • Ponraj, D.1    Makjanic, J.2    Thong, P.S.3
  • 84
    • 0036119134 scopus 로고    scopus 로고
    • Beneficial effects of blood donation on high density lipoprotein concentration and the oxidative potential of low density lipoprotein
    • van Jaarsveld H, Pool GF. Beneficial effects of blood donation on high density lipoprotein concentration and the oxidative potential of low density lipoprotein. Atherosclerosis. 2002;161:395-402.
    • (2002) Atherosclerosis , vol.161 , pp. 395-402
    • Van Jaarsveld, H.1    Pool, G.F.2
  • 85
    • 3242780850 scopus 로고    scopus 로고
    • The role of labile iron pool in cardiovascular diseases
    • Kruszewski M. The role of labile iron pool in cardiovascular diseases. Acta Biochim Pol. 2004;51:471-480.
    • (2004) Acta Biochim Pol , vol.51 , pp. 471-480
    • Kruszewski, M.1
  • 86
    • 0031963619 scopus 로고    scopus 로고
    • Iron, free radicals, and oxidative injury
    • McCord JM. Iron, free radicals, and oxidative injury. Semin Hematol. 1998;35:5-12.
    • (1998) Semin Hematol , vol.35 , pp. 5-12
    • McCord, J.M.1
  • 87
    • 0027279233 scopus 로고
    • Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease
    • Gey KF. Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease. Br Med Bull. 1993;49:679-699.
    • (1993) Br Med Bull , vol.49 , pp. 679-699
    • Gey, K.F.1
  • 89
    • 0030008268 scopus 로고    scopus 로고
    • Fenton chemistry: An introduction
    • Wardman P, Candeias LP. Fenton chemistry: an introduction. Radiat Res. 1996;145:523-531.
    • (1996) Radiat Res , vol.145 , pp. 523-531
    • Wardman, P.1    Candeias, L.P.2
  • 90
    • 0037465438 scopus 로고    scopus 로고
    • Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension
    • Li L, Fink GD, Watts SW, et al. Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation .2003;107:1053-1058.
    • (2003) Circulation , vol.107 , pp. 1053-1058
    • Li, L.1    Fink, G.D.2    Watts, S.W.3
  • 91
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: Contribution to alterations ofvasomotor tone
    • Rajagopalan S, Kurz S, Munzel T, et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations ofvasomotor tone. J Clin Invest. 1996;97:1916-1923.
    • (1996) J Clin Invest , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3
  • 92
    • 0031443873 scopus 로고    scopus 로고
    • Localization of a consti-tutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
    • Pagano PJ, Clark JK, Cifuentes-Pagano ME, et al. Localization of a consti-tutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II. Proc Natl Acad Sci USA. 1997;94:14483-14488.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14483-14488
    • Pagano, P.J.1    Clark, J.K.2    Cifuentes-Pagano, M.E.3
  • 93
    • 0034987955 scopus 로고    scopus 로고
    • Adhesion molecules and their role in vascular disease
    • Krieglstein CF, Granger DN. Adhesion molecules and their role in vascular disease. Am JHypertens. 2001;14:44S-54S.
    • (2001) Am JHypertens , vol.14
    • Krieglstein, C.F.1    Granger, D.N.2
  • 94
    • 0035024867 scopus 로고    scopus 로고
    • VCAM-1 is critical in atherosclerosis
    • Ley K, Huo Y. VCAM-1 is critical in atherosclerosis. J Clin Invest. 2001;107:1209-1210.
    • (2001) J Clin Invest , vol.107 , pp. 1209-1210
    • Ley, K.1    Huo, Y.2
  • 95
    • 4744349398 scopus 로고    scopus 로고
    • Structure and regulation of the neutrophil respiratory burst oxidase: Comparison with nonphagocyte oxidases
    • Quinn MT, Gauss KA. Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases. J Leukoc Biol. 2004;76:760-781.
    • (2004) J Leukoc Biol , vol.76 , pp. 760-781
    • Quinn, M.T.1    Gauss, K.A.2
  • 96
    • 0030827909 scopus 로고    scopus 로고
    • Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits
    • Yu L, Zhen L, Dinauer MC. Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits. J Biol Chem. 1997;272:27288-27294.
    • (1997) J Biol Chem , vol.272 , pp. 27288-27294
    • Yu, L.1    Zhen, L.2    Dinauer, M.C.3
  • 97
    • 3142581994 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability
    • Taille C, El-Benna J, Lanone S, et al. Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability. J Biol Chem. 2004;279: 28681-28688.
    • (2004) J Biol Chem , vol.279 , pp. 28681-28688
    • Taille, C.1    El-Benna, J.2    Lanone, S.3
  • 98
    • 65549090148 scopus 로고    scopus 로고
    • Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: Inhibition by desferrioxamine
    • Li L, Frei B. Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine. Arterioscler Thromb Vasc Biol. 2009;29: 732-738.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 732-738
    • Li, L.1    Frei, B.2
  • 99
    • 39349085544 scopus 로고    scopus 로고
    • Can iron chelators influence the progression of atherosclerosis?
    • Marx JJ, Kartikasari AE, Georgiou NA. Can iron chelators influence the progression of atherosclerosis? Hemoglobin. 2008;32:123-134.
    • (2008) Hemoglobin , vol.32 , pp. 123-134
    • Marx, J.J.1    Kartikasari, A.E.2    Georgiou, N.A.3
  • 100
    • 0037443734 scopus 로고    scopus 로고
    • Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions
    • Minqin R, Watt F, Huat BT, et al. Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions. Free Radic Biol Med. 2003;34:746-752.
    • (2003) Free Radic Biol Med , vol.34 , pp. 746-752
    • Minqin, R.1    Watt, F.2    Huat, B.T.3
  • 101
    • 0003714337 scopus 로고    scopus 로고
    • Elemental changes in atherosclerotic lesions using nuclear microscopy
    • Thong PS, Selley M, Watt F. Elemental changes in atherosclerotic lesions using nuclear microscopy. Cell Mol Biol (Noisy-le-grand). 1996;42:103-110.
    • (1996) Cell Mol Biol (Noisy-le-grand) , vol.42 , pp. 103-110
    • Thong, P.S.1    Selley, M.2    Watt, F.3
  • 102
    • 15944403231 scopus 로고    scopus 로고
    • The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit
    • Minqin R, Rajendran R, Pan N, et al. The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit. Free Radic Biol Med. 2005;38: 1206-1211.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1206-1211
    • Minqin, R.1    Rajendran, R.2    Pan, N.3
  • 103
    • 0026649212 scopus 로고
    • Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions
    • Smith C, Mitchinson MJ, Aruoma OI, et al. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. Biochem J. 1992;286(pt 3):901-905.
    • (1992) Biochem J , vol.286 , Issue.PART 3 , pp. 901-905
    • Smith, C.1    Mitchinson, M.J.2    Aruoma, O.I.3
  • 104
    • 0019434645 scopus 로고
    • Iron and the sex difference in heart disease risk
    • Sullivan JL. Iron and the sex difference in heart disease risk. Lancet. 1981;1:1293-1294.
    • (1981) Lancet , vol.1 , pp. 1293-1294
    • Sullivan, J.L.1
  • 105
    • 0037326156 scopus 로고    scopus 로고
    • Are menstruating women protected from heart disease because of, or in spite of, estrogen? Relevance to the iron hypothesis
    • Sullivan JL. Are menstruating women protected from heart disease because of, or in spite of, estrogen? Relevance to the iron hypothesis. Am Heart J. 2003;145:190-194.
    • (2003) Am Heart J , vol.145 , pp. 190-194
    • Sullivan, J.L.1
  • 106
    • 0016373413 scopus 로고
    • Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia
    • Stone NJ, Levy RI, Fredrickson DS, et al. Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia. Circulation. 1974;49: 476-488.
    • (1974) Circulation , vol.49 , pp. 476-488
    • Stone, N.J.1    Levy, R.I.2    Fredrickson, D.S.3
  • 107
    • 0017093859 scopus 로고
    • Menopause and risk of cardiovascular disease: The Framingham study
    • Kannel WB, Hjortland MC, McNamara PM, et al. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med. 1976;85: 447-452.
    • (1976) Ann Intern Med , vol.85 , pp. 447-452
    • Kannel, W.B.1    Hjortland, M.C.2    McNamara, P.M.3
  • 108
    • 0032547326 scopus 로고    scopus 로고
    • Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women
    • Hulley S, Grady D, Bush T, et al; Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA. 1998;280:605-613.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3
  • 109
    • 0042093742 scopus 로고    scopus 로고
    • Estrogen plus progestin and the risk of coronary heart disease
    • Manson JE, Hsia J, Johnson KC, et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med. 2003;349:523-534.
    • (2003) N Engl J Med , vol.349 , pp. 523-534
    • Manson, J.E.1    Hsia, J.2    Johnson, K.C.3
  • 110
    • 0026800818 scopus 로고
    • High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men
    • Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation. 1992;86:803-811.
    • (1992) Circulation , vol.86 , pp. 803-811
    • Salonen, J.T.1    Nyyssonen, K.2    Korpela, H.3
  • 111
    • 0033596677 scopus 로고    scopus 로고
    • Coronary heart disease and iron status: Meta-analyses of prospective studies
    • Danesh J, Appleby P. Coronary heart disease and iron status: meta-analyses of prospective studies. Circulation. 1999;99:852-854.
    • (1999) Circulation , vol.99 , pp. 852-854
    • Danesh, J.1    Appleby, P.2
  • 112
    • 0017626225 scopus 로고
    • Effect of blood donation on iron stores as evaluated by serum ferritin
    • Finch CA, Cook JD, Labbe RF, et al. Effect of blood donation on iron stores as evaluated by serum ferritin. Blood. 1977;50:441-447.
    • (1977) Blood , vol.50 , pp. 441-447
    • Finch, C.A.1    Cook, J.D.2    Labbe, R.F.3
  • 113
    • 0025766118 scopus 로고
    • The influence of blood donation on iron stores assessed by serum ferritin and hemoglobin in a population survey of 1359 Danish women
    • Milman N, Kirchhoff M. The influence of blood donation on iron stores assessed by serum ferritin and hemoglobin in a population survey of 1359 Danish women. Ann Hematol. 1991;63:27-32.
    • (1991) Ann Hematol , vol.63 , pp. 27-32
    • Milman, N.1    Kirchhoff, M.2
  • 114
    • 0030972547 scopus 로고    scopus 로고
    • Cohort study of relation between donating blood and risk of myocardial infarction in 2682 men in eastern Finland
    • Tuomainen TP, Salonen R, Nyyssonen K, et al. Cohort study of relation between donating blood and risk of myocardial infarction in 2682 men in eastern Finland. BMJ. 1997;314:793-794.
    • (1997) BMJ , vol.314 , pp. 793-794
    • Tuomainen, T.P.1    Salonen, R.2    Nyyssonen, K.3
  • 115
    • 0030809782 scopus 로고    scopus 로고
    • Possible association of a reduction in cardiovascular events with blood donation
    • Meyers DG, Strickland D, Maloley PA, et al. Possible association of a reduction in cardiovascular events with blood donation. Heart. 1997;78: 188-193.
    • (1997) Heart , vol.78 , pp. 188-193
    • Meyers, D.G.1    Strickland, D.2    Maloley, P.A.3
  • 116
    • 0035830410 scopus 로고    scopus 로고
    • Blood donations and risk of coronary heart disease in men
    • Ascherio A, Rimm EB, Giovannucci E, et al. Blood donations and risk of coronary heart disease in men. Circulation. 2001;103:52-57.
    • (2001) Circulation , vol.103 , pp. 52-57
    • Ascherio, A.1    Rimm, E.B.2    Giovannucci, E.3
  • 117
    • 0036727362 scopus 로고    scopus 로고
    • A historical cohort study of the effect of lowering body iron through blood donation on incident cardiac events
    • Meyers DG, Jensen KC, Menitove JE. A historical cohort study of the effect of lowering body iron through blood donation on incident cardiac events. Transfusion. 2002;42:1135-1139.
    • (2002) Transfusion , vol.42 , pp. 1135-1139
    • Meyers, D.G.1    Jensen, K.C.2    Menitove, J.E.3
  • 118
    • 33846964515 scopus 로고    scopus 로고
    • Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: A randomized controlled trial
    • Zacharski LR, Chow BK, Howes PS, et al. Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: a randomized controlled trial. JAMA. 2007;297:603-610.
    • (2007) JAMA , vol.297 , pp. 603-610
    • Zacharski, L.R.1    Chow, B.K.2    Howes, P.S.3
  • 119
    • 23244441664 scopus 로고    scopus 로고
    • Iron stores and vascular function in voluntary blood donors
    • Zheng H, Cable R, Spencer B, et al. Iron stores and vascular function in voluntary blood donors. Arterioscler Thromb Vasc Biol. 2005;25:1577-1583.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1577-1583
    • Zheng, H.1    Cable, R.2    Spencer, B.3
  • 120
    • 0036636392 scopus 로고    scopus 로고
    • Effect of dexrazoxane on homocysteine-induced endothelial dysfunction in normal subjects
    • Zheng H, Dimayuga C, Hudaihed A, et al. Effect of dexrazoxane on homocysteine-induced endothelial dysfunction in normal subjects. Arterio-scler Thromb Vasc Biol. 2002;22:E15-E18.
    • (2002) Arterio-scler Thromb Vasc Biol , vol.22
    • Zheng, H.1    Dimayuga, C.2    Hudaihed, A.3
  • 121
    • 0035849568 scopus 로고    scopus 로고
    • Iron chelation improves endothelial function in patients with coronary artery disease
    • Duffy SJ, Biegelsen ES, Holbrook M, et al. Iron chelation improves endothelial function in patients with coronary artery disease. Circulation. 2001;103:2799-2804.
    • (2001) Circulation , vol.103 , pp. 2799-2804
    • Duffy, S.J.1    Biegelsen, E.S.2    Holbrook, M.3
  • 122
    • 32544461020 scopus 로고    scopus 로고
    • Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects
    • Zheng H, Huang X, Zhang Q, et al. Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects. Kidney Int. 2006;69: 679-684.
    • (2006) Kidney Int , vol.69 , pp. 679-684
    • Zheng, H.1    Huang, X.2    Zhang, Q.3
  • 123
    • 0036515321 scopus 로고    scopus 로고
    • Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo
    • Rooyakkers TM, Stroes ES, Kooistra MP, et al. Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo. Eur J Clin Invest. 2002;32(suppl 1):9-16.
    • (2002) Eur J Clin Invest , vol.32 , Issue.SUPPL. 1 , pp. 9-16
    • Rooyakkers, T.M.1    Stroes, E.S.2    Kooistra, M.P.3
  • 124
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A, Bolton WK, Browne JK, et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med. 1998;339: 584-590.
    • (1998) N Engl J Med , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.