Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction

Journal of the American College of Cardiology

Volumn 45, Issue 3, 2005, Pages 391-399

  Ishani, Areef ^a,d   Weinhandl, Eric ^b   Zhao, Zihong ^b   Gilbertson, David T ^b   Collins, Allan J ^a,b   Yusuf, Salim ^c   Herzog, Charles A ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^c MCMASTER UNIVERSITY   (Canada)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; PLACEBO;

ADULT; ANEMIA; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA BASE; DISEASE ASSOCIATION; DISEASE COURSE; DRUG SCREENING; FEMALE; HEART FAILURE; HEART LEFT VENTRICLE FAILURE; HEMATOCRIT; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; NONBIOLOGICAL MODEL; PATIENT; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; SURVIVAL;

AGED; ANEMIA; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ENALAPRIL; FEMALE; FOLLOW-UP STUDIES; HEMATOCRIT; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 13244268473     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2004.10.038     Document Type: Article

References (33)

1. National Heart, Lung, and Blood Institute Morbidity and Mortality: 2002 Chart Book on Cardiovascular, Lung and Blood Diseases 2002 National Institutes of Health Bethesda, MD
2. National Heart, Lung, and Blood Institute Data Fact Sheet: Congestive Heart Failure in the United States: A New Epidemic 2002 National Institutes of Health Bethesda, MD
3. D. Levy, S. Kenchaiah, M.G. Larson Long-term trends in the incidence of and survival with heart failure N Engl J Med 347 2002 1397 1402
4. T.B. Horwich, G.C. Fonarow, M.A. Hamilton, W.R. MacLellan, J. Borenstein Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure J Am Coll Cardiol 39 2002 1780 1786
5. A. Al Ahmad, W.M. Rand, G. Manjunath Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction J Am Coll Cardiol 38 2001 955 962
6. S.A. Hunt, D.W. Baker, M.H. Chin ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the International Society for Heart and Lung Transplantation; endorsed by the Heart Failure Society of America Circulation 104 2001 2996 3007
7. A. Yildiz, N. Cine, V. Akkaya Comparison of the effects of enalapril and losartan on posttransplantation erythrocytosis in renal transplant recipients: prospective randomized study Transplantation 72 2001 542 544
8. A.Y. Wang, A.W. Yu, C.W. Lam Effects of losartan or enalapril on hemoglobin, circulating erythropoietin, and insulin-like growth factor-1 in patients with and without posttransplant erythrocytosis [Online] Am J Kidney Dis 39 2002 600 608
9. R. Plata, A. Cornejo, C. Arratia Angiotensin-converting-enzyme inhibition therapy in altitude polycythaemia: a prospective randomised trial Lancet 359 2002 663 666
10. D. Glicklich, T. Kapoian, H. Mian, J. Gilman, V. Tellis, H. Croizat Effects of erythropoietin, angiotensin II, and angiotensin-converting enzyme inhibitor on erythroid precursors in patients with posttransplantation erythrocytosis Transplantation 68 1999 62 66
11. Studies Of Left Ventricular Dysfunction (SOLVD)--rationale, design and methods: two trials that evaluate the effect of enalapril in patients with reduced ejection fraction Am J Cardiol 66 1990 315 322
12. The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure N Engl J Med 325 1991 293 302
13. The SOLVD Investigators Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions N Engl J Med 327 1992 685 691
14. World Health Organization Nutritional Anaemias: Report of a WHO Scientific Group 1968 World Health Organization Geneva, Switzerland
15. R.B. D'Agostino Jr Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group Stat Med 17 1998 2265 2281
16. G.T. Griffing, J.C. Melby Enalapril (MK-421) and the white cell count and haematocrit Lancet 1 1982 1361
17. H. Hirakata, K. Onoyama, K. Iseki, H. Kumagai, S. Fujimi, T. Omae Worsening of anemia induced by long-term use of captopril in hemodialysis patients Am J Nephrol 4 1984 355 360
18. R.S. Gaston, B.A. Julian, A.G. Diethelm, J.J. Curtis Effects of enalapril on erythrocytosis after renal transplantation Ann Intern Med 115 1991 954 955
19. D. Glicklich, L. Burris, A. Urban Angiotensin-converting enzyme inhibition induces apoptosis in erythroid precursors and affects insulin-like growth factor-1 in posttransplantation erythrocytosis J Am Soc Nephrol 12 2001 1958 1964
20. M.S. MacGregor, P.A. Rowe, M.A. Watson, R.S. Rodger, B.J. Junor, J.D. Briggs Treatment of postrenal transplant erythrocytosis Long-term efficacy and safety of angiotensin-converting enzyme inhibitors Nephron 74 1996 517 521
21. J.V. Torregrosa, J.M. Campistol, M. Montesinos, A.G. Rogada, F. Oppenheimer, J. Andreu Efficacy of captopril on posttransplant erythrocytosis Long-term follow-up Transplantation 58 1994 311 314
22. M. Mrug, T. Stopka, B.A. Julian, J.F. Prchal, J.T. Prchal Angiotensin II stimulates proliferation of normal early erythroid progenitors J Clin Invest 100 1997 2310 2314
23. J. Cole, D. Ertoy, H. Lin Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice J Clin Invest 106 2000 1391 1398
24. L.F. Morrone, S. Di Paolo, F. Logoluso Interference of angiotensin-converting enzyme inhibitors on erythropoiesis in kidney transplant recipients: role of growth factors and cytokines Transplantation 64 1997 913 918
25. M. Azizi, A. Rousseau, E. Ezan Acute angiotensin-converting enzyme inhibition increases the plasma level of the natural stem cell regulator N-acetyl-seryl-aspartyl-lysyl-proline J Clin Invest 97 1996 839 844
26. M. Alexander, K. Grumbach, L. Remy, R. Rowell, B.M. Massie Congestive heart failure hospitalizations and survival in California: patterns according to race/ethnicity Am Heart J 137 1999 919 927
27. J.A. Ezekowitz, F.A. McAlister, P.W. Armstrong Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12 065 patients with new-onset heart failure Circulation 107 2003 223 225
28. D. Mozaffarian, R. Nye, W.C. Levy Anemia predicts mortality in severe heart failure: the Prospective Randomized Amlodipine Survival Evaluation (PRAISE) J Am Coll Cardiol 41 2003 1933 1939
29. G.A. MacGowan, R.L. Kormos, D.M. McNamara Predicting short-term outcome in severely ill heart failure patients: implications regarding listing for urgent cardiac transplantation and patient selection for temporary ventricular assist device support J Card Fail 4 1998 169 175
30. W.C. Wu, S.S. Rathore, Y. Wang, M.J. Radford, H.M. Krumholz Blood transfusion in elderly patients with acute myocardial infarction N Engl J Med 345 2001 1230 1236
31. R.N. Foley, P.S. Parfrey, J.D. Harnett, G.M. Kent, D.C. Murray, P.E. Barre The impact of anemia on cardiomyopathy, morbidity, and mortality in end-stage renal disease Am J Kidney Dis 28 1996 53 61
32. D.M. Mancini, S.D. Katz, C.C. Lang, J. LaManca, A. Hudaihed, A.S. Androne Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure Circulation 107 2003 294 299
33. D.S. Silverberg, D. Wexler, D. Sheps The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study J Am Coll Cardiol 37 2001 1775 1780