메뉴 건너뛰기




Volumn 88, Issue 1, 2010, Pages 41-55

Dual targeting of CCR2 and CCR5: Therapeutic potential for immunologic and cardiovascular diseases

Author keywords

Chemokine receptors; Chemokines; Disease pathogenesis; Monocyte macrophage recruitment

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5;

EID: 77954676361     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1009671     Document Type: Review
Times cited : (96)

References (156)
  • 1
    • 0036262275 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature
    • Murphy, P. M. (2002) International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature. Pharmacol. Rev. 54, 227-229.
    • (2002) Pharmacol. Rev. , vol.54 , pp. 227-229
    • Murphy, P.M.1
  • 2
    • 0035260881 scopus 로고    scopus 로고
    • Chemokines and disease
    • Gerard, C., Rollins, B. J. (2001) Chemokines and disease. Nat. Immunol. 2, 108-115.
    • (2001) Nat. Immunol. , vol.2 , pp. 108-115
    • Gerard, C.1    Rollins, B.J.2
  • 3
    • 32144454172 scopus 로고    scopus 로고
    • The many roles of chemokines and chemokine receptors in inflammation
    • Charo, I. F., Ransohoff, R. M. (2006) The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354, 610-621.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 4
    • 41149111580 scopus 로고    scopus 로고
    • Chemokines and their receptors: Drug targets in immunity and inflammation
    • Viola, A., Luster, A. D. (2008) Chemokines and their receptors: drug targets in immunity and inflammation. Annu. Rev. Pharmacol. Toxicol. 48, 171-197.
    • (2008) Annu. Rev. Pharmacol. Toxicol. , vol.48 , pp. 171-197
    • Viola, A.1    Luster, A.D.2
  • 5
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean, M., Carrington, M., Winkler, C., Huttley, G. A., Smith, M. W., Allikmets, R., Goedert, J. J., Buchbinder, S. P., Vittinghoff, E., Gomperts, E., Donfield, S., Vlahov, D., Kaslow, R., Saah, A., Rinaldo, C., Detels, R., O'Brien, S. J. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 273, 1856-1862.
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1    Carrington, M.2    Winkler, C.3    Huttley, G.A.4    Smith, M.W.5    Allikmets, R.6    Goedert, J.J.7    Buchbinder, S.P.8    Vittinghoff, E.9    Gomperts, E.10    Donfield, S.11    Vlahov, D.12    Kaslow, R.13    Saah, A.14    Rinaldo, C.15    Detels, R.16    O'Brien, S.J.17
  • 10
    • 0017077503 scopus 로고
    • The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy
    • Miller, L. H., Mason, S. J., Clyde, D. F., McGinniss, M. H. (1976) The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. N. Engl. J. Med. 295, 302-304.
    • (1976) N. Engl. J. Med. , vol.295 , pp. 302-304
    • Miller, L.H.1    Mason, S.J.2    Clyde, D.F.3    McGinniss, M.H.4
  • 11
    • 0029001881 scopus 로고
    • Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals
    • Tournamille, C., Colin, Y., Cartron, J. P., Le Van Kim, C. (1995) Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals. Nat. Genet. 10, 224-228.
    • (1995) Nat. Genet. , vol.10 , pp. 224-228
    • Tournamille, C.1    Colin, Y.2    Cartron, J.P.3    Le Van Kim, C.4
  • 12
    • 67649425653 scopus 로고    scopus 로고
    • Chemokine receptor antagonists: Part 1
    • Pease, J. E., Horuk, R. (2009) Chemokine receptor antagonists: part 1. Expert Opin. Ther. Pat. 19, 39-58.
    • (2009) Expert Opin. Ther. Pat. , vol.19 , pp. 39-58
    • Pease, J.E.1    Horuk, R.2
  • 13
    • 67649341169 scopus 로고    scopus 로고
    • Chemokine receptor antagonists: Part 2
    • Pease, J. E., Horuk, R. (2009) Chemokine receptor antagonists: part 2. Expert Opin. Ther. Pat. 19, 199-221.
    • (2009) Expert Opin. Ther. Pat. , vol.19 , pp. 199-221
    • Pease, J.E.1    Horuk, R.2
  • 14
    • 62549162552 scopus 로고    scopus 로고
    • Maraviroc, a CCR5 coreceptor antagonist that blocks entry of human immunodeficiency virus type 1
    • Hunt, J. S., Romanelli, F. (2009) Maraviroc, a CCR5 coreceptor antagonist that blocks entry of human immunodeficiency virus type 1. Pharmacotherapy 29, 295-304.
    • (2009) Pharmacotherapy , vol.29 , pp. 295-304
    • Hunt, J.S.1    Romanelli, F.2
  • 15
    • 62149135221 scopus 로고    scopus 로고
    • Plerixafor: In patients with non-Hodgkin's lymphoma or multiple myeloma
    • Wagstaff, A. J. (2009) Plerixafor: in patients with non-Hodgkin's lymphoma or multiple myeloma. Drugs 69, 319-326.
    • (2009) Drugs , vol.69 , pp. 319-326
    • Wagstaff, A.J.1
  • 16
    • 0242273333 scopus 로고    scopus 로고
    • Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization
    • Charo, I. F., Peters, W. (2003) Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization. Microcirculation 10, 259-264.
    • (2003) Microcirculation , vol.10 , pp. 259-264
    • Charo, I.F.1    Peters, W.2
  • 17
    • 33747047231 scopus 로고    scopus 로고
    • CCR5 antagonists: The answer to inflammatory disease?
    • Ness, T. L., Kunkel, S. L., Hogaboam, C. M. (2006) CCR5 antagonists: the answer to inflammatory disease? Expert Opin. Ther. Pat. 16, 1051-1065.
    • (2006) Expert Opin. Ther. Pat. , vol.16 , pp. 1051-1065
    • Ness, T.L.1    Kunkel, S.L.2    Hogaboam, C.M.3
  • 18
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • Geissmann, F., Jung, S., Littman, D. R. (2003) Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19, 71-82.
    • (2003) Immunity , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 20
    • 0029811908 scopus 로고    scopus 로고
    • Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes
    • Loetscher, P., Seitz, M., Baggiolini, M., Moser, B. (1996) Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J. Exp. Med. 184, 569-577.
    • (1996) J. Exp. Med. , vol.184 , pp. 569-577
    • Loetscher, P.1    Seitz, M.2    Baggiolini, M.3    Moser, B.4
  • 21
    • 0030809822 scopus 로고    scopus 로고
    • Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
    • Boring, L., Gosling, J., Chensue, S. W., Kunkel, S. L., Farese Jr., R. V., Broxmeyer, H. E., Charo, I. F. (1997) Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J. Clin. Invest. 100, 2552-2561.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2552-2561
    • Boring, L.1    Gosling, J.2    Chensue, S.W.3    Kunkel, S.L.4    Farese Jr., R.V.5    Broxmeyer, H.E.6    Charo, I.F.7
  • 23
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • DOI 10.1084/jem.186.10.1757
    • Kurihara, T., Warr, G., Loy, J., Bravo, R. (1997) Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186, 1757-1762. (Pubitemid 27506288)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.10 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 29
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • DOI 10.1084/jem.186.10.1757
    • Kurihara, T., Warr, G., Loy, J., Bravo, R. (1997) Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186, 1757-1762. (Pubitemid 27506288)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.10 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 31
    • 0037625155 scopus 로고    scopus 로고
    • TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection
    • Serbina, N. V., Salazar-Mather, T. P., Biron, C. A., Kuziel, W. A., Pamer, E. G. (2003) TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19, 59-70.
    • (2003) Immunity , vol.19 , pp. 59-70
    • Serbina, N.V.1    Salazar-Mather, T.P.2    Biron, C.A.3    Kuziel, W.A.4    Pamer, E.G.5
  • 32
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • Serbina, N. V., Pamer, E. G. (2006) Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 7, 311-317.
    • (2006) Nat. Immunol. , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 35
    • 0030699387 scopus 로고    scopus 로고
    • Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
    • Kurihara, T., Warr, G., Loy, J., Bravo, R. (1997) Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186, 1757-1762.
    • (1997) J. Exp. Med. , vol.186 , pp. 1757-1762
    • Kurihara, T.1    Warr, G.2    Loy, J.3    Bravo, R.4
  • 36
    • 0032536531 scopus 로고    scopus 로고
    • Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
    • Lu, B., Rutledge, B. J., Gu, L., Fiorillo, J., Lukacs, N. W., Kunkel, S. L., North, R., Gerard, C., Rollins, B. J. (1998) Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 187, 601-608.
    • (1998) J. Exp. Med. , vol.187 , pp. 601-608
    • Lu, B.1    Rutledge, B.J.2    Gu, L.3    Fiorillo, J.4    Lukacs, N.W.5    Kunkel, S.L.6    North, R.7    Gerard, C.8    Rollins, B.J.9
  • 37
    • 0035189760 scopus 로고    scopus 로고
    • The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium
    • Huo, Y., Weber, C., Forlow, S. B., Sperandio, M., Thatte, J., Mack, M., Jung, S., Littman, D. R., Ley, K. (2001) The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. J. Clin. Invest. 108, 1307-1314.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1307-1314
    • Huo, Y.1    Weber, C.2    Forlow, S.B.3    Sperandio, M.4    Thatte, J.5    Mack, M.6    Jung, S.7    Littman, D.R.8    Ley, K.9
  • 39
    • 13844317079 scopus 로고    scopus 로고
    • MIP-1α utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells
    • Oba, Y., Lee, J. W., Ehrlich, L. A., Chung, H. Y., Jelinek, D. F., Callander, N. S., Horuk, R., Choi, S. J., Roodman, G. D. (2005) MIP-1α utilizes both CCR1 and CCR5 to induce osteoclast formation and increase adhesion of myeloma cells to marrow stromal cells. Exp. Hematol. 33, 272-278.
    • (2005) Exp. Hematol. , vol.33 , pp. 272-278
    • Oba, Y.1    Lee, J.W.2    Ehrlich, L.A.3    Chung, H.Y.4    Jelinek, D.F.5    Callander, N.S.6    Horuk, R.7    Choi, S.J.8    Roodman, G.D.9
  • 42
    • 0343396569 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis
    • Katschke Jr., K. J., Rottman, J. B., Ruth, J. H., Qin, S., Wu, L., LaRosa, G., Ponath, P., Park, C. C., Pope, R. M., Koch, A. E. (2001) Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis. Arthritis Rheum. 44, 1022-1032.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1022-1032
    • Katschke Jr., K.J.1    Rottman, J.B.2    Ruth, J.H.3    Qin, S.4    Wu, L.5    LaRosa, G.6    Ponath, P.7    Park, C.C.8    Pope, R.M.9    Koch, A.E.10
  • 44
    • 0030612473 scopus 로고    scopus 로고
    • An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
    • Gong, J. H., Ratkay, L. G., Waterfield, J. D., Clark-Lewis, I. (1997) An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J. Exp. Med. 186, 131-137.
    • (1997) J. Exp. Med. , vol.186 , pp. 131-137
    • Gong, J.H.1    Ratkay, L.G.2    Waterfield, J.D.3    Clark-Lewis, I.4
  • 45
    • 68149160827 scopus 로고    scopus 로고
    • An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis
    • Rafei, M., Berchiche, Y. A., Birman, E., Boivin, M. N., Young, Y. K., Wu, J. H., Heveker, N., Galipeau, J. (2009) An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis. J. Immunol. 183, 1759-1766.
    • (2009) J. Immunol. , vol.183 , pp. 1759-1766
    • Rafei, M.1    Berchiche, Y.A.2    Birman, E.3    Boivin, M.N.4    Young, Y.K.5    Wu, J.H.6    Heveker, N.7    Galipeau, J.8
  • 46
    • 0033846366 scopus 로고    scopus 로고
    • C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis
    • Youssef, S., Maor, G., Wildbaum, G., Grabie, N., Gour-Lavie, A., Karin, N. (2000) C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis. J. Clin. Invest. 106, 361-371.
    • (2000) J. Clin. Invest. , vol.106 , pp. 361-371
    • Youssef, S.1    Maor, G.2    Wildbaum, G.3    Grabie, N.4    Gour-Lavie, A.5    Karin, N.6
  • 47
    • 0030909913 scopus 로고    scopus 로고
    • The role of monocyte chemoattractant protein-1 (MCP-1) in the pathogenesis of collagen-induced arthritis in rats
    • Ogata, H., Takeya, M., Yoshimura, T., Takagi, K., Takahashi, K. (1997) The role of monocyte chemoattractant protein-1 (MCP-1) in the pathogenesis of collagen-induced arthritis in rats. J. Pathol. 182, 106-114.
    • (1997) J. Pathol. , vol.182 , pp. 106-114
    • Ogata, H.1    Takeya, M.2    Yoshimura, T.3    Takagi, K.4    Takahashi, K.5
  • 49
    • 0031908574 scopus 로고    scopus 로고
    • Role of chemokines and cytokines in a reactivation model of arthritis in rats induced by injection with streptococcal cell walls
    • Schrier, D. J., Schimmer, R. C., Flory, C. M., Tung, D. K., Ward, P. A. (1998) Role of chemokines and cytokines in a reactivation model of arthritis in rats induced by injection with streptococcal cell walls. J. Leukoc. Biol. 63, 359-363.
    • (1998) J. Leukoc. Biol. , vol.63 , pp. 359-363
    • Schrier, D.J.1    Schimmer, R.C.2    Flory, C.M.3    Tung, D.K.4    Ward, P.A.5
  • 50
    • 0031849593 scopus 로고    scopus 로고
    • Production and regulation of monocyte chemoattractant protein-1 in lipopolysaccharide- or monosodium urate crystal-induced arthritis in rabbits: Roles of tumor necrosis factor α, interleukin-1, and interleukin-8
    • Matsukawa, A., Miyazaki, S., Maeda, T., Tanase, S., Feng, L., Ohkawara, S., Yoshinaga, M., Yoshimura, T. (1998) Production and regulation of monocyte chemoattractant protein-1 in lipopolysaccharide- or monosodium urate crystal-induced arthritis in rabbits: roles of tumor necrosis factor α, interleukin-1, and interleukin-8. Lab. Invest. 78, 973-985.
    • (1998) Lab. Invest. , vol.78 , pp. 973-985
    • Matsukawa, A.1    Miyazaki, S.2    Maeda, T.3    Tanase, S.4    Feng, L.5    Ohkawara, S.6    Yoshinaga, M.7    Yoshimura, T.8
  • 53
    • 0034659767 scopus 로고    scopus 로고
    • Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate mediated colitis: Lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte associated Th2-type immune response in the intestine
    • Andres, P. G., Beck, P. L., Mizoguchi, E., Mizoguchi, A., Bhan, A. K., Dawson, T., Kuziel, W. A., Maeda, N., MacDermott, R. P., Podolsky, D. K., Reinecker, H. C. (2000) Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte associated Th2-type immune response in the intestine. J. Immunol. 164, 6303-6312.
    • (2000) J. Immunol. , vol.164 , pp. 6303-6312
    • Andres, P.G.1    Beck, P.L.2    Mizoguchi, E.3    Mizoguchi, A.4    Bhan, A.K.5    Dawson, T.6    Kuziel, W.A.7    Maeda, N.8    MacDermott, R.P.9    Podolsky, D.K.10    Reinecker, H.C.11
  • 56
    • 10744225261 scopus 로고    scopus 로고
    • Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism
    • Lee, I., Wang, L., Wells, A. D., Ye, Q., Han, R., Dorf, M. E., Kuziel, W. A., Rollins, B. J., Chen, L., Hancock, W. W. (2003) Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism. J. Immunol. 171, 6929-6935.
    • (2003) J. Immunol. , vol.171 , pp. 6929-6935
    • Lee, I.1    Wang, L.2    Wells, A.D.3    Ye, Q.4    Han, R.5    Dorf, M.E.6    Kuziel, W.A.7    Rollins, B.J.8    Chen, L.9    Hancock, W.W.10
  • 58
    • 54249138126 scopus 로고    scopus 로고
    • Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model
    • Alexis, J. D., Pyo, R. T., Chereshnev, I., Katz, J., Rollins, B. J., Charo, I. F., Taubman, M. B. (2008) Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model. J. Vasc. Res. 45, 538-546.
    • (2008) J. Vasc. Res. , vol.45 , pp. 538-546
    • Alexis, J.D.1    Pyo, R.T.2    Chereshnev, I.3    Katz, J.4    Rollins, B.J.5    Charo, I.F.6    Taubman, M.B.7
  • 59
    • 23744462672 scopus 로고    scopus 로고
    • Local cytokine environments drive aneurysm formation in allografted aortas
    • Shimizu, K., Libby, P., Mitchell, R. N. (2005) Local cytokine environments drive aneurysm formation in allografted aortas. Trends Cardiovasc. Med. 15, 142-148.
    • (2005) Trends Cardiovasc. Med. , vol.15 , pp. 142-148
    • Shimizu, K.1    Libby, P.2    Mitchell, R.N.3
  • 61
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2(-/-) mice reveals a role for chemokines in the initiation of atherosclerosis
    • DOI 10.1038/29788
    • Boring, L., Gosling, J., Cleary, M., Charo, I. F. (1998) Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394, 894-897. (Pubitemid 28410911)
    • (1998) Nature , vol.394 , Issue.6696 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 62
    • 0033060017 scopus 로고    scopus 로고
    • Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice
    • DOI 10.1016/S0021-9150(98)00318-9, PII S0021915098003189
    • Dawson, T. C., Kuziel, W. A., Osahar, T. A., Maeda, N. (1999) Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis 143, 205-211. (Pubitemid 29138720)
    • (1999) Atherosclerosis , vol.143 , Issue.1 , pp. 205-211
    • C Dawson, T.1    A Kuziel, W.2    A Osahar, T.3    Maeda, N.4
  • 63
    • 23844437323 scopus 로고    scopus 로고
    • Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo
    • DOI 10.1161/CIRCULATIONAHA.104.520718
    • Veillard, N. R., Steffens, S., Pelli, G., Lu, B., Kwak, B. R., Gerard, C., Charo, I. F., Mach, F. (2005) Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo. Circulation 112, 870-878. (Pubitemid 41170074)
    • (2005) Circulation , vol.112 , Issue.6 , pp. 870-878
    • Veillard, N.R.1    Steffens, S.2    Pelli, G.3    Lu, B.4    Kwak, B.R.5    Gerard, C.6    Charo, I.F.7    Mach, F.8
  • 64
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu, L., Okada, Y., Clinton, S. K., Gerard, C., Sukhova, G. K., Libby, P., Rollins, B. J. (1998) Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol. Cell 2, 275-281. (Pubitemid 128373654)
    • (1998) Molecular Cell , vol.2 , Issue.2 , pp. 275-281
    • Gu, L.1    Okada, Y.2    Clinton, S.K.3    Gerard, C.4    Sukhova, G.K.5    Libby, P.6    Rollins, B.J.7
  • 65
    • 0033559691 scopus 로고    scopus 로고
    • MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
    • Gosling, J., Slaymaker, S., Gu, L., Tseng, S., Zlot, C. H., Young, S. G., Rollins, B. J., Charo, I. F. (1999) MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J. Clin. Invest. 103, 773-778.
    • (1999) J. Clin. Invest. , vol.103 , pp. 773-778
    • Gosling, J.1    Slaymaker, S.2    Gu, L.3    Tseng, S.4    Zlot, C.H.5    Young, S.G.6    Rollins, B.J.7    Charo, I.F.8
  • 67
    • 0037137305 scopus 로고    scopus 로고
    • Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice
    • Inoue, S., Egashira, K., Ni, W., Kitamoto, S., Usui, M., Otani, K., Ishibashi, M., Hiasa, K., Nishida, K., Takeshita, A. (2002) Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice. Circulation 106, 2700-2706.
    • (2002) Circulation , vol.106 , pp. 2700-2706
    • Inoue, S.1    Egashira, K.2    Ni, W.3    Kitamoto, S.4    Usui, M.5    Otani, K.6    Ishibashi, M.7    Hiasa, K.8    Nishida, K.9    Takeshita, A.10
  • 68
    • 12144288691 scopus 로고    scopus 로고
    • Monocyte Chemoattractant Protein-1 is an Essential Inflammatory Mediator in Angiotensin II-Induced Progression of Established Atherosclerosis in Hypercholesterolemic Mice
    • DOI 10.1161/01.ATV.0000118275.60121.2b
    • Ni, W., Kitamoto, S., Ishibashi, M., Usui, M., Inoue, S., Hiasa, K., Zhao, Q., Nishida, K., Takeshita, A., Egashira, K. (2004) Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice. Arterioscler. Thromb. Vasc. Biol. 24, 534-539. (Pubitemid 38326149)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.3 , pp. 534-539
    • Ni, W.1    Kitamoto, S.2    Ishibashi, M.3    Usui, M.4    Inoue, S.5    Hiasa, K.-I.6    Zhao, Q.7    Nishida, K.-I.8    Takeshita, A.9    Egashira, K.10
  • 73
    • 9344245693 scopus 로고    scopus 로고
    • Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets
    • Schober, A., Zernecke, A., Liehn, E. A., von Hundelshausen, P., Knarren, S., Kuziel, W. A., Weber, C. (2004) Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets. Circ. Res. 95, 1125-1133.
    • (2004) Circ. Res. , vol.95 , pp. 1125-1133
    • Schober, A.1    Zernecke, A.2    Liehn, E.A.3    Von Hundelshausen, P.4    Knarren, S.5    Kuziel, W.A.6    Weber, C.7
  • 75
    • 67649236757 scopus 로고    scopus 로고
    • Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice
    • Eefting, D., Bot, I., de Vries, M. R., Schepers, A., van Bockel, J. H., Van Berkel, T. J., Biessen, E. A., Quax, P. H. (2009) Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice. J. Vasc. Surg. 50, 152-160.
    • (2009) J. Vasc. Surg. , vol.50 , pp. 152-160
    • Eefting, D.1    Bot, I.2    De Vries, M.R.3    Schepers, A.4    Van Bockel, J.H.5    Van Berkel, T.J.6    Biessen, E.A.7    Quax, P.H.8
  • 78
    • 0033047511 scopus 로고    scopus 로고
    • Anti-monocyte chemoattractant protein-1/monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries
    • Furukawa, Y., Matsumori, A., Ohashi, N., Shioi, T., Ono, K., Harada, A., Matsushima, K., Sasayama, S. (1999) Anti-monocyte chemoattractant protein-1/monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries. Circ. Res. 84, 306-314. (Pubitemid 29095571)
    • (1999) Circulation Research , vol.84 , Issue.3 , pp. 306-314
    • Furukawa, Y.1    Matsumori, A.2    Ohashi, N.3    Shioi, T.4    Ono, K.5    Harada, A.6    Matsushima, K.7    Sasayama, S.8
  • 79
    • 0036832156 scopus 로고    scopus 로고
    • Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys
    • Usui, M., Egashira, K., Ohtani, K., Kataoka, C., Ishibashi, M., Hiasa, K., Katoh, M., Zhao, Q., Kitamoto, S., Takeshita, A. (2002) Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys. FASEB J. 16, 1838-1840.
    • (2002) FASEB J. , vol.16 , pp. 1838-1840
    • Usui, M.1    Egashira, K.2    Ohtani, K.3    Kataoka, C.4    Ishibashi, M.5    Hiasa, K.6    Katoh, M.7    Zhao, Q.8    Kitamoto, S.9    Takeshita, A.10
  • 80
    • 0037129903 scopus 로고    scopus 로고
    • Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits
    • DOI 10.1161/01.CIR.0000018603.67989.71
    • Mori, E., Komori, K., Yamaoka, T., Tanii, M., Kataoka, C., Takeshita, A., Usui, M., Egashira, K., Sugimachi, K. (2002) Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits. Circulation 105, 2905-2910. (Pubitemid 34666106)
    • (2002) Circulation , vol.105 , Issue.24 , pp. 2905-2910
    • Mori, E.1    Komori, K.2    Yamaoka, T.3    Tanii, M.4    Kataoka, C.5    Takeshita, A.6    Usui, M.7    Egashira, K.8    Sugimachi, K.9
  • 81
    • 4444295588 scopus 로고    scopus 로고
    • Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys
    • DOI 10.1038/sj.gt.3302288
    • Ohtani, K., Usui, M., Nakano, K., Kohjimoto, Y., Kitajima, S., Hirouchi, Y., Li, X. H., Kitamoto, S., Takeshita, A., Egashira, K. (2004) Antimonocyte chemoattractant protein-1 gene therapy reduces experimental instent restenosis in hypercholesterolemic rabbits and monkeys. Gene Ther. 11, 1273-1282. (Pubitemid 39173434)
    • (2004) Gene Therapy , vol.11 , Issue.16 , pp. 1273-1282
    • Ohtani, K.1    Usui, M.2    Nakano, K.3    Kohjimoto, Y.4    Kitajima, S.5    Hirouchi, Y.6    Li, X.-H.7    Kitamoto, S.8    Takeshita, A.9    Egashira, K.10
  • 83
    • 34249315109 scopus 로고    scopus 로고
    • Blockade of monocyte chemoattractant protein-1 by adenoviral gene transfer inhibits experimental vein graft neointimal formation
    • DOI 10.1016/j.jvs.2007.01.066, PII S0741521407002327
    • Tatewaki, H., Egashira, K., Kimura, S., Nishida, T., Morita, S., Tominaga, R. (2007) Blockade of monocyte chemoattractant protein-1 by adenoviral gene transfer inhibits experimental vein graft neointimal formation. J. Vasc. Surg. 45, 1236-1243. (Pubitemid 46817835)
    • (2007) Journal of Vascular Surgery , vol.45 , Issue.6 , pp. 1236-1243
    • Tatewaki, H.1    Egashira, K.2    Kimura, S.3    Nishida, T.4    Morita, S.5    Tominaga, R.6
  • 84
    • 0037040835 scopus 로고    scopus 로고
    • Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: Inhibitory potential depends on type of injury and leukocytes targeted
    • DOI 10.1161/hh0402.105956
    • Horvath, C., Welt, F. G., Nedelman, M., Rao, P., Rogers, C. (2002) Targeting CCR2 or CD18 inhibits experimental in-stent restenosis in primates: inhibitory potential depends on type of injury and leukocytes targeted. Circ. Res. 90, 488-494. (Pubitemid 34633920)
    • (2002) Circulation Research , vol.90 , Issue.4 , pp. 488-494
    • Horvath, C.1    Welt, F.G.P.2    Nedelman, M.3    Rao, P.4    Rogers, C.5
  • 85
    • 34848874132 scopus 로고    scopus 로고
    • Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys
    • DOI 10.1016/j.atherosclerosis.2006.10.029, PII S0021915006006496
    • Nakano, K., Egashira, K., Ohtani, K., Zhao, G., Funakoshi, K., Ihara, Y., Sunagawa, K. (2007) Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys. Atherosclerosis 194, 309-316. (Pubitemid 47513092)
    • (2007) Atherosclerosis , vol.194 , Issue.2 , pp. 309-316
    • Nakano, K.1    Egashira, K.2    Ohtani, K.3    Zhao, G.4    Funakoshi, K.5    Ihara, Y.6    Sunagawa, K.7
  • 91
    • 20444451569 scopus 로고    scopus 로고
    • Decreased IgG production but increased MIP-1β expression in collagen-induced arthritis in C-C chemokine receptor 5-deficient mice
    • Bao, L., Zhu, Y., Zhu, J., Lindgren, J. U. (2005) Decreased IgG production but increased MIP-1β expression in collagen-induced arthritis in C-C chemokine receptor 5-deficient mice. Cytokine 31, 64-71.
    • (2005) Cytokine , vol.31 , pp. 64-71
    • Bao, L.1    Zhu, Y.2    Zhu, J.3    Lindgren, J.U.4
  • 98
    • 0034568503 scopus 로고    scopus 로고
    • CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis
    • Zapico, I., Coto, E., Rodríguez, A., Alvarez, C., Torre, J. C., Alvarez, V. (2000) CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis. Genes Immun. 1, 288-289.
    • (2000) Genes Immun. , vol.1 , pp. 288-289
    • Zapico, I.1    Coto, E.2    Rodríguez, A.3    Alvarez, C.4    Torre, J.C.5    Alvarez, V.6
  • 99
    • 0031596378 scopus 로고    scopus 로고
    • The Δ32 deletion of CCR5 receptor in rheumatoid arthritis
    • Cooke, S. P., Forrest, G., Venables, P. J., Hajeer, A. (1998) The Δ32 deletion of CCR5 receptor in rheumatoid arthritis. Arthritis Rheum. 41, 1135-1136.
    • (1998) Arthritis Rheum. , vol.41 , pp. 1135-1136
    • Cooke, S.P.1    Forrest, G.2    Venables, P.J.3    Hajeer, A.4
  • 100
    • 33646152126 scopus 로고    scopus 로고
    • Negative association between the chemokine receptor CCR5-Δ32 polymorphism and rheumatoid arthritis: A meta-analysis
    • Prahalad, S. (2006) Negative association between the chemokine receptor CCR5-Δ32 polymorphism and rheumatoid arthritis: a meta-analysis. Genes Immun. 7, 264-268.
    • (2006) Genes Immun. , vol.7 , pp. 264-268
    • Prahalad, S.1
  • 102
    • 0036687024 scopus 로고    scopus 로고
    • A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses
    • Yang, Y. F., Mukai, T., Gao, P., Yamaguchi, N., Ono, S., Iwaki, H., Obika, S., Imanishi, T., Tsujimura, T., Hamaoka, T., Fujiwara, H. (2002) A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses. Eur. J. Immunol. 32, 2124-2132.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2124-2132
    • Yang, Y.F.1    Mukai, T.2    Gao, P.3    Yamaguchi, N.4    Ono, S.5    Iwaki, H.6    Obika, S.7    Imanishi, T.8    Tsujimura, T.9    Hamaoka, T.10    Fujiwara, H.11
  • 104
    • 23844499474 scopus 로고    scopus 로고
    • The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis
    • Tokuyama, H., Ueha, S., Kurachi, M., Matsushima, K., Moriyasu, F., Blumberg, R. S., Kakimi, K. (2005) The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis. Int. Immunol. 17, 1023-1034.
    • (2005) Int. Immunol. , vol.17 , pp. 1023-1034
    • Tokuyama, H.1    Ueha, S.2    Kurachi, M.3    Matsushima, K.4    Moriyasu, F.5    Blumberg, R.S.6    Kakimi, K.7
  • 106
    • 67651236888 scopus 로고    scopus 로고
    • CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice
    • Li, J., Zhang, K., Ye, P., Wang, S., Xia, J. (2009) CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice. Clin. Exp. Immunol. 157, 437-445.
    • (2009) Clin. Exp. Immunol. , vol.157 , pp. 437-445
    • Li, J.1    Zhang, K.2    Ye, P.3    Wang, S.4    Xia, J.5
  • 107
    • 18644372263 scopus 로고    scopus 로고
    • Absence of recipient CCR5 promotes early and increased allospecific antibody responses to cardiac allografts
    • Amano, H., Bickerstaff, A., Orosz, C. G., Novick, A. C., Toma, H., Fairchild, R. L. (2005) Absence of recipient CCR5 promotes early and increased allospecific antibody responses to cardiac allografts. J. Immunol. 174, 6499-6508. (Pubitemid 40663845)
    • (2005) Journal of Immunology , vol.174 , Issue.10 , pp. 6499-6508
    • Amano, H.1    Bickerstaff, A.2    Orosz, C.G.3    Novick, A.C.4    Toma, H.5    Fairchild, R.L.6
  • 110
    • 33846631304 scopus 로고    scopus 로고
    • Blocking the CC Chemokine Receptor 5 Pathway by Antisense Peptide Nucleic Acid Prolongs Islet Allograft Survival
    • DOI 10.1016/j.transproceed.2006.10.193, PII S0041134506014564
    • Yang, L., Liu, Y. F., Wu, G., Zhang, J. L., Wang, F. S., Fu, D. Z., Zhao, G. H., Li, T. M. (2007) Blocking the CC chemokine receptor 5 pathway by antisense peptide nucleic acid prolongs islet allograft survival. Transplant. Proc. 39, 185-190. (Pubitemid 46175953)
    • (2007) Transplantation Proceedings , vol.39 , Issue.1 , pp. 185-190
    • Yang, L.1    Liu, Y.F.2    Wu, G.3    Zhang, J.L.4    Wang, F.S.5    Fu, D.Z.6    Zhao, G.H.7    Li, T.M.8
  • 117
    • 1042291188 scopus 로고    scopus 로고
    • Antagonism of RANTES Receptors Reduces Atherosclerotic Plaque Formation in Mice
    • DOI 10.1161/01.RES.0000109793.17591.4E
    • Veillard, N. R., Kwak, B., Pelli, G., Mulhaupt, F., James, R. W., Proudfoot, A. E., Mach, F. (2004) Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice. Circ. Res. 94, 253-261. (Pubitemid 38197459)
    • (2004) Circulation Research , vol.94 , Issue.2 , pp. 253-261
    • Veillard, N.R.1    Kwak, B.2    Pelli, G.3    Mulhaupt, F.4    James, R.W.5    Proudfoot, A.E.I.6    Mach, F.7
  • 119
    • 33744472746 scopus 로고    scopus 로고
    • Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: Involvement of IL-10
    • DOI 10.1182/blood-2005-09-3922
    • Zernecke, A., Liehn, E. A., Gao, J. L., Kuziel, W. A., Murphy, P. M., Weber, C. (2006) Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10. Blood 107, 4240-4243. (Pubitemid 43801346)
    • (2006) Blood , vol.107 , Issue.11 , pp. 4240-4243
    • Zernecke, A.1    Liehn, E.A.2    Gao, J.-L.3    Kuziel, W.A.4    Murphy, P.M.5    Weber, C.6
  • 121
    • 0037126048 scopus 로고    scopus 로고
    • Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury
    • Schober, A., Manka, D., von Hundelshausen, P., Huo, Y., Hanrath, P., Sarembock, I. J., Ley, K., Weber, C. (2002) Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury. Circulation 106, 1523-1529.
    • (2002) Circulation , vol.106 , pp. 1523-1529
    • Schober, A.1    Manka, D.2    Von Hundelshausen, P.3    Huo, Y.4    Hanrath, P.5    Sarembock, I.J.6    Ley, K.7    Weber, C.8
  • 124
  • 128
    • 44649181711 scopus 로고    scopus 로고
    • MLN1202, a novel CCR2 antagonist, decreases C-reactive protein in patients at risk for atherosclerotic cardiovascular disease in a double blind placebo controlled study
    • MLN1202 in ACSVD Study Group Abstract 874
    • Davidson, M., Lekstrom-Himes, J., Gilbert, J., Donaldson, D., Lee, Y., Hu, M., Xu, J., MLN1202 in ACSVD Study Group (2007) Abstract 874. MLN1202, a novel CCR2 antagonist, decreases C-reactive protein in patients at risk for atherosclerotic cardiovascular disease in a double blind placebo controlled study. Circulation 116, II-171.
    • (2007) Circulation , vol.116
    • Davidson, M.1    Lekstrom-Himes, J.2    Gilbert, J.3    Donaldson, D.4    Lee, Y.5    Hu, M.6    Xu, J.7
  • 136
    • 41649100060 scopus 로고    scopus 로고
    • Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice
    • Combadière, C., Potteaux, S., Rodero, M., Simon, T., Pezard, A., Esposito, B., Merval, R., Proudfoot, A., Tedgui, A., Mallat, Z. (2008) Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation 117, 1649-1657.
    • (2008) Circulation , vol.117 , pp. 1649-1657
    • Combadière, C.1    Potteaux, S.2    Rodero, M.3    Simon, T.4    Pezard, A.5    Esposito, B.6    Merval, R.7    Proudfoot, A.8    Tedgui, A.9    Mallat, Z.10
  • 139
    • 85047687223 scopus 로고    scopus 로고
    • -/- mice reveals a role for fractalkine in atherogenesis
    • DOI 10.1172/JCI200315555
    • Lesnik, P., Haskell, C. A., Charo, I. F. (2003) Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. J. Clin. Invest. 111, 333-340. (Pubitemid 36182209)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.3 , pp. 333-340
    • Lesnik, P.1    Haskell, C.A.2    Charo, I.F.3
  • 140
    • 70349564487 scopus 로고    scopus 로고
    • Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis
    • Gautier, E. L., Jakubzick, C., Randolph, G. J. (2009) Regulation of the migration and survival of monocyte subsets by chemokine receptors and its relevance to atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 29, 1412-1418.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1412-1418
    • Gautier, E.L.1    Jakubzick, C.2    Randolph, G.J.3
  • 141
    • 0033178679 scopus 로고    scopus 로고
    • Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: Role of secreted MCP-1 in the regulation of the chemotactic response
    • Fantuzzi, L., Borghi, P., Ciolli, V., Pavlakis, G., Belardelli, F., Gessani, S. (1999) Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: role of secreted MCP-1 in the regulation of the chemotactic response. Blood 194, 875-883. (Pubitemid 29361817)
    • (1999) Blood , vol.94 , Issue.3 , pp. 875-883
    • Fantuzzi, L.1    Borghi, P.2    Ciolli, V.3    Pavlakis, G.4    Belardelli, F.5    Gessani, S.6
  • 142
    • 0035115994 scopus 로고    scopus 로고
    • Increase of CCR1 and CCR5 expression and enhanced functional response to MIP-1α during differentiation of human monocytes to macrophages
    • Kaufmann, A., Salentin, R., Gemsa, D., Sprenger, H. (2001) Increase of CCR1 and CCR5 expression and enhanced functional response to MIP-1 α during differentiation of human monocytes to macrophages. J. Leukoc. Biol. 69, 248-252. (Pubitemid 32163437)
    • (2001) Journal of Leukocyte Biology , vol.69 , Issue.2 , pp. 248-252
    • Kaufmann, A.1    Salentin, R.2    Gemsa, D.3    Sprenger, H.4
  • 143
    • 0343396569 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis
    • Katschke Jr., K. J., Rottman, J. B., Ruth, J. H., Qin, S., Wu, L., LaRosa, G., Ponath, P., Park, C. C., Pope, R. M., Koch, A. E. (2001) Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis. Arthritis Rheum. 44, 1022-1032.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1022-1032
    • Katschke Jr., K.J.1    Rottman, J.B.2    Ruth, J.H.3    Qin, S.4    Wu, L.5    LaRosa, G.6    Ponath, P.7    Park, C.C.8    Pope, R.M.9    Koch, A.E.10
  • 144
    • 0030035550 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1β, and MIP-1α
    • Raport, C. J., Gosling, J., Schweickart, V. L., Gray, P. W., Charo, I. F. (1996) Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1β, and MIP-1α. J. Biol. Chem. 271, 17161-17166.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17161-17166
    • Raport, C.J.1    Gosling, J.2    Schweickart, V.L.3    Gray, P.W.4    Charo, I.F.5
  • 145
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E. A., Murphy, P. M., Farber, J. M. (1999) Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 146
    • 26844529383 scopus 로고    scopus 로고
    • Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection
    • Glass, W. G., Lim, J. K., Cholera, R., Pletnev, A. G., Gao, J. L., Murphy, P. M. (2005) Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection. J. Exp. Med. 202, 1087-1098.
    • (2005) J. Exp. Med. , vol.202 , pp. 1087-1098
    • Glass, W.G.1    Lim, J.K.2    Cholera, R.3    Pletnev, A.G.4    Gao, J.L.5    Murphy, P.M.6
  • 148
    • 39149133656 scopus 로고    scopus 로고
    • Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: A meta-analysis of 4 cohorts in the US epidemic
    • Lim, J. K., Louie, C. Y., Glaser, C., Jean, C., Johnson, B., Johnson, H., McDermott, D. H., Murphy, P. M. (2008) Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic. J. Infect. Dis. 197, 262-265.
    • (2008) J. Infect. Dis. , vol.197 , pp. 262-265
    • Lim, J.K.1    Louie, C.Y.2    Glaser, C.3    Jean, C.4    Johnson, B.5    Johnson, H.6    McDermott, D.H.7    Murphy, P.M.8
  • 150
    • 42649108339 scopus 로고    scopus 로고
    • Monocyte-mediated defense against microbial pathogens
    • Serbina, N. V., Jia, T., Hohl, T. M., Pamer, E. G. (2008) Monocyte-mediated defense against microbial pathogens. Annu. Rev. Immunol. 26, 421-452.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 421-452
    • Serbina, N.V.1    Jia, T.2    Hohl, T.M.3    Pamer, E.G.4
  • 151
    • 65549149088 scopus 로고    scopus 로고
    • Safety concerns about CCR5 as an antiviral target
    • Telenti, A. (2009) Safety concerns about CCR5 as an antiviral target. Curr. Opin. HIV AIDS 4, 131-135.
    • (2009) Curr. Opin. HIV AIDS , vol.4 , pp. 131-135
    • Telenti, A.1
  • 152
    • 0036242256 scopus 로고    scopus 로고
    • Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
    • Dambach, D. M., Watson, L. M., Gray, K. R., Durham, S. K., Laskin, D. L. (2002) Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology 35, 1093-1103.
    • (2002) Hepatology , vol.35 , pp. 1093-1103
    • Dambach, D.M.1    Watson, L.M.2    Gray, K.R.3    Durham, S.K.4    Laskin, D.L.5
  • 153
    • 0038221365 scopus 로고    scopus 로고
    • C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse
    • Ajuebor, M. N., Hogaboam, C. M., Le, T., Swain, M. G. (2003) C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse. J. Immunol. 170, 5252-5259.
    • (2003) J. Immunol. , vol.170 , pp. 5252-5259
    • Ajuebor, M.N.1    Hogaboam, C.M.2    Le, T.3    Swain, M.G.4
  • 154
    • 20444365171 scopus 로고    scopus 로고
    • Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells
    • Ajuebor, M. N., Aspinall, A. I., Zhou, F., Le, T., Yang, Y., Urbanski, S. J., Sidobre, S., Kronenberg, M., Hogaboam, C. M., Swain, M. G. (2005) Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells. J. Immunol. 174, 8027-8037.
    • (2005) J. Immunol. , vol.174 , pp. 8027-8037
    • Ajuebor, M.N.1    Aspinall, A.I.2    Zhou, F.3    Le, T.4    Yang, Y.5    Urbanski, S.J.6    Sidobre, S.7    Kronenberg, M.8    Hogaboam, C.M.9    Swain, M.G.10
  • 155
    • 34447338611 scopus 로고    scopus 로고
    • CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis
    • Ajuebor, M. N., Wondimu, Z., Hogaboam, C. M., Le, T., Proudfoot, A. E., Swain, M. G. (2007) CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis. Am. J. Pathol. 170, 1975-1988.
    • (2007) Am. J. Pathol. , vol.170 , pp. 1975-1988
    • Ajuebor, M.N.1    Wondimu, Z.2    Hogaboam, C.M.3    Le, T.4    Proudfoot, A.E.5    Swain, M.G.6
  • 156
    • 35548965968 scopus 로고    scopus 로고
    • CCR5 antagonists: Comparison of efficacy, side effects, pharmacokinetics and interactions - review of the literature
    • Emmelkamp, J. M., Rockstroh, J. K. (2007) CCR5 antagonists: comparison of efficacy, side effects, pharmacokinetics and interactions - review of the literature. Eur. J. Med. Res. 12, 409-417.
    • (2007) Eur. J. Med. Res. , vol.12 , pp. 409-417
    • Emmelkamp, J.M.1    Rockstroh, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.