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Volumn 103, Issue 6, 1999, Pages 773-778

MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; LOW DENSITY LIPOPROTEIN RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1;

EID: 0033559691     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI5624     Document Type: Review
Times cited : (610)

References (46)
  • 1
    • 0028970042 scopus 로고
    • Cell biology of atherosclerosis
    • Ross, R. 1995. Cell biology of atherosclerosis. Annu. Rev. Physiol. 57:791-804.
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 791-804
    • Ross, R.1
  • 2
    • 0019491124 scopus 로고
    • The role of the monocyte in atherogenesis. I. Transition of blood-borne monocytes into foam cells in fatty lesions
    • Gerrity, R.G. 1981. The role of the monocyte in atherogenesis. I. Transition of blood-borne monocytes into foam cells in fatty lesions. Am. J. Pathol. 103:181-190.
    • (1981) Am. J. Pathol. , vol.103 , pp. 181-190
    • Gerrity, R.G.1
  • 3
    • 0021261107 scopus 로고
    • Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation
    • Faggiotto, A., Ross, R., and Harker, L. 1984. Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation. Arteriosclerosis. 4:323-340.
    • (1984) Arteriosclerosis , vol.4 , pp. 323-340
    • Faggiotto, A.1    Ross, R.2    Harker, L.3
  • 4
    • 0030825407 scopus 로고    scopus 로고
    • Chemokines
    • Rollins, B.J. 1997. Chemokines. Blood. 90:909-928.
    • (1997) Blood , vol.90 , pp. 909-928
    • Rollins, B.J.1
  • 5
    • 0025281588 scopus 로고
    • Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells
    • Cushing, S.D., et al. 1990. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc. Natl. Acad. Sci. USA. 87:5134-5138.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5134-5138
    • Cushing, S.D.1
  • 6
    • 0026075699 scopus 로고
    • Monocyte chemoattractant protein-1 in human atheromatous plaques
    • Nelken, N.A., Coughlin, S.R., Gordon, D., and Wilcox, J.N. 1991. Monocyte chemoattractant protein-1 in human atheromatous plaques. J. Clin. Invest. 88:1121-1127.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1121-1127
    • Nelken, N.A.1    Coughlin, S.R.2    Gordon, D.3    Wilcox, J.N.4
  • 7
    • 0025954705 scopus 로고
    • Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions
    • Ylä-Herttuala, S., et al. 1991. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. USA. 88:5252-5256.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5252-5256
    • Ylä-Herttuala, S.1
  • 8
    • 0026648108 scopus 로고
    • Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates
    • Yu, X., et al. 1992. Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates. Proc. Natl. Acad. Sci. USA. 89:6953-6957.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6953-6957
    • Yu, X.1
  • 9
    • 0026536066 scopus 로고
    • Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells
    • Piedrahita, J.A., Zhang, S.H., Hagaman, J.R., Oliver, P.M., and Maeda, N. 1992. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 89:4471-4475.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4471-4475
    • Piedrahita, J.A.1    Zhang, S.H.2    Hagaman, J.R.3    Oliver, P.M.4    Maeda, N.5
  • 10
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump, A. S., et al. 1992. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71:343-353.
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1
  • 11
    • 0032572719 scopus 로고    scopus 로고
    • Decreased lesion formation in CCR2 mice reveals a role for chemokines in the initiation of atherosclerosis
    • Boring, L., Gosling, J., Cleary, M., and Charo, I.F. 1998. Decreased lesion formation in CCR2 mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 394:894-897.
    • (1998) Nature , vol.394 , pp. 894-897
    • Boring, L.1    Gosling, J.2    Cleary, M.3    Charo, I.F.4
  • 12
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S., et al. 1993. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92:883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1
  • 13
    • 0028345073 scopus 로고
    • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
    • Ishibashi, S., Goldstein, J.L., Brown, M.S., Herz, J., and Burns, D.K. 1994. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J. Clin. Invest. 93:1885-1893.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1885-1893
    • Ishibashi, S.1    Goldstein, J.L.2    Brown, M.S.3    Herz, J.4    Burns, D.K.5
  • 14
    • 0032134003 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice
    • Gu, L. et al. 1998. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol. Cell. 2:275-281.
    • (1998) Mol. Cell. , vol.2 , pp. 275-281
    • Gu, L.1
  • 15
    • 0027145132 scopus 로고
    • Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a)
    • Linton, M.F., et al. 1993. Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). J. Clin. Invest. 92:3029-3037.
    • (1993) J. Clin. Invest. , vol.92 , pp. 3029-3037
    • Linton, M.F.1
  • 16
    • 0028960478 scopus 로고
    • Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
    • Purcell-Huynh, D.A., et al. 1995. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J. Clin. Invest. 95:2246-2257.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2246-2257
    • Purcell-Huynh, D.A.1
  • 17
    • 0031956120 scopus 로고    scopus 로고
    • Genetically modified mice for the study of apolipoprotein B
    • Kim, E., and Young, S.G. 1998. Genetically modified mice for the study of apolipoprotein B. J. Lipid Res. 39:703-723.
    • (1998) J. Lipid Res. , vol.39 , pp. 703-723
    • Kim, E.1    Young, S.G.2
  • 18
    • 0025322603 scopus 로고
    • Synthetic low and high fat diets for the study of atherosclerosis in the mouse
    • Nishina, P.M., Versruyft, J., and Paigen, B. 1990. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J. Lipid Res. 31:859-869.
    • (1990) J. Lipid Res. , vol.31 , pp. 859-869
    • Nishina, P.M.1    Versruyft, J.2    Paigen, B.3
  • 19
    • 0028918775 scopus 로고
    • Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes
    • Farese, R.V. Jr., Ruland, S.L., Flynn, L.M., Stokowski, R.P., and Young, S.G. 1995. Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA. 92:1774-1778.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1774-1778
    • Farese R.V., Jr.1    Ruland, S.L.2    Flynn, L.M.3    Stokowski, R.P.4    Young, S.G.5
  • 20
    • 0022885505 scopus 로고
    • Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B
    • Young, S.G., Smith, R.S., Hogle, D.M., Curtiss, L.K., and Witztum, J.L. 1986. Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B. Clin. Chem. 32:1484-1490.
    • (1986) Clin. Chem. , vol.32 , pp. 1484-1490
    • Young, S.G.1    Smith, R.S.2    Hogle, D.M.3    Curtiss, L.K.4    Witztum, J.L.5
  • 22
    • 0022449841 scopus 로고
    • Conservation of the low density lipoprotein receptor-binding domain of apoprotein B: Demonstration by a new monoclonal antibody, MB47
    • Young, S.G., Witztum, J.L., Casal, D.C., Curtiss, L.K., and Bernstein, S. 1986. Conservation of the low density lipoprotein receptor-binding domain of apoprotein B: demonstration by a new monoclonal antibody, MB47. Arteriosclerosis. 6:178-188.
    • (1986) Arteriosclerosis , vol.6 , pp. 178-188
    • Young, S.G.1    Witztum, J.L.2    Casal, D.C.3    Curtiss, L.K.4    Bernstein, S.5
  • 23
    • 0032894472 scopus 로고    scopus 로고
    • Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice
    • Zlot, C.H., et al. 1999. Generation of monoclonal antibodies specific for mouse apolipoprotein B-100 in apolipoprotein B-48-only mice. J. Lipid Res. 40:76-84.
    • (1999) J. Lipid Res. , vol.40 , pp. 76-84
    • Zlot, C.H.1
  • 24
    • 0032555195 scopus 로고    scopus 로고
    • Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes
    • Raabe, M., et al. 1998. Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. Proc. Natl. Acad. Sci. USA. 95:8686-8691.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8686-8691
    • Raabe, M.1
  • 25
    • 0030995490 scopus 로고    scopus 로고
    • Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice
    • Kim, E., Lowenson, J.D., MacLaren, D.C., Clarke, S., and Young, S.G. 1997. Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice. Proc. Natl. Acad. Sci. USA. 94:6132-6137.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6132-6137
    • Kim, E.1    Lowenson, J.D.2    MacLaren, D.C.3    Clarke, S.4    Young, S.G.5
  • 26
    • 0032521141 scopus 로고    scopus 로고
    • Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia: Analysis of a new mouse model with a nonsense mutation in the Apob gene
    • Kim, E., Cham, C.M., Véniant, M.M., Ambroziak, P., and Young, S.G. 1998. Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia: analysis of a new mouse model with a nonsense mutation in the Apob gene. J. Clin. Invest. 101:1468-1477.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1468-1477
    • Kim, E.1    Cham, C.M.2    Véniant, M.M.3    Ambroziak, P.4    Young, S.G.5
  • 27
    • 0242695290 scopus 로고    scopus 로고
    • Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100
    • Véniant, M.M., et al. 1997. Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100. J. Clin. Invest. 100:180-188.
    • (1997) J. Clin. Invest. , vol.100 , pp. 180-188
    • Véniant, M.M.1
  • 28
    • 0026057848 scopus 로고
    • Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses
    • Rubin, E.M., Ishida, B.Y., Clift, S.M., and Krauss, R.M. 1991. Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses. Proc. Natl. Acad. Sci. USA. 88:434-438.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 434-438
    • Rubin, E.M.1    Ishida, B.Y.2    Clift, S.M.3    Krauss, R.M.4
  • 29
    • 0028167663 scopus 로고
    • Apolipoprotein A-I transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice
    • Paszty, C., Maeda, N., Verstuyft, and Rubin, E.M. 1994. Apolipoprotein A-I transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J. Clin. Invest. 94:899-903.
    • (1994) J. Clin. Invest. , vol.94 , pp. 899-903
    • Paszty, C.1    Maeda, N.2    Verstuyft3    Rubin, E.M.4
  • 30
    • 0028596350 scopus 로고
    • Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic mice
    • Liu, A.C., Lawn, R.M., Verstuyft, J.G., and Rubin, E.M. 1994. Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic mice. J. Lipid Res. 35:2263-2267.
    • (1994) J. Lipid Res. , vol.35 , pp. 2263-2267
    • Liu, A.C.1    Lawn, R.M.2    Verstuyft, J.G.3    Rubin, E.M.4
  • 31
    • 0030662044 scopus 로고    scopus 로고
    • Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5′-element confers appropriate transgene expression in the intestine
    • Nielsen, L.B., et al. 1997. Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5′-element confers appropriate transgene expression in the intestine. J. Biol. Chem. 272:29752-29758.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29752-29758
    • Nielsen, L.B.1
  • 32
    • 0022003324 scopus 로고
    • Variation in susceptibility to atherosclerosis among inbred strains of mice
    • Paigen, B., Morrow, A., Brandon, C., Mitchell, D., and Holmes, P. 1985. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis. 57:65-73.
    • (1985) Atherosclerosis , vol.57 , pp. 65-73
    • Paigen, B.1    Morrow, A.2    Brandon, C.3    Mitchell, D.4    Holmes, P.5
  • 34
    • 0023391441 scopus 로고
    • Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility
    • Paigen, B., Albee, D., Holmes, P.A., and Mitchell, D. 1987. Genetic analysis of murine strains C57BL/6J and C3H/HeJ to confirm the map position of Ath-1, a gene determining atherosclerosis susceptibility. Biochem. Genet. 25:501-511.
    • (1987) Biochem. Genet. , vol.25 , pp. 501-511
    • Paigen, B.1    Albee, D.2    Holmes, P.A.3    Mitchell, D.4
  • 35
    • 0027976942 scopus 로고
    • Atherosclerosis in mice lacking apo E: Evaluation of lesional development and progression
    • Reddick, R.L., Zhang, S.H., and Maeda, N. 1994. Atherosclerosis in mice lacking apo E: evaluation of lesional development and progression. Arterioscler. Thromb. 14:141-147.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 141-147
    • Reddick, R.L.1    Zhang, S.H.2    Maeda, N.3
  • 36
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang, S.H., Reddick, R.L., Piedrahita, J.A., and Maeda, N. 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258:468-471.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 37
    • 0027958084 scopus 로고
    • Apo E-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
    • Nakashima, Y., Plump, A.S., Raines, E.W., Breslow, J.L., and Ross, R 1994. Apo E-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb. 14:133-140.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 133-140
    • Nakashima, Y.1    Plump, A.S.2    Raines, E.W.3    Breslow, J.L.4    Ross, R.5
  • 38
    • 0028862192 scopus 로고
    • Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
    • Tangirala, R.K., Rubin, E.M., and Palinski, W. 1995. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J. Lipid Res. 36:2320-2328.
    • (1995) J. Lipid Res. , vol.36 , pp. 2320-2328
    • Tangirala, R.K.1    Rubin, E.M.2    Palinski, W.3
  • 39
    • 0000743072 scopus 로고
    • Association of coronary atherosclerosis with hyperapobetalipoproteinemia: Increased protein but normal cholesterol levels in human plasma low density (β) lipoproteins
    • Sniderman, A., et al. 1980. Association of coronary atherosclerosis with hyperapobetalipoproteinemia: increased protein but normal cholesterol levels in human plasma low density (β) lipoproteins. Proc. Natl. Acad. Sci. USA. 77:604-608.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 604-608
    • Sniderman, A.1
  • 40
    • 0022448680 scopus 로고
    • Metabolic basis of hyperapobetalipoproteinemia: Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia
    • Teng, B., Sniderman, A.D., Soutar, A.K., and Thompson, G.R. 1986. Metabolic basis of hyperapobetalipoproteinemia: turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia. J. Clin. Invest. 77:663-672.
    • (1986) J. Clin. Invest. , vol.77 , pp. 663-672
    • Teng, B.1    Sniderman, A.D.2    Soutar, A.K.3    Thompson, G.R.4
  • 41
    • 0026609119 scopus 로고
    • From familial combined hyperlipidemia to hyperapoB: Unravelling the overproduction of hepatic apolipoprotein B
    • Sniderman, A., Brown, B.C., Stewart, B.F., and Cianflone, K. 1992. From familial combined hyperlipidemia to hyperapoB: unravelling the overproduction of hepatic apolipoprotein B. Curr. Opin. Lipidol. 3:137-142.
    • (1992) Curr. Opin. Lipidol. , vol.3 , pp. 137-142
    • Sniderman, A.1    Brown, B.C.2    Stewart, B.F.3    Cianflone, K.4
  • 42
    • 0029128048 scopus 로고
    • Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a)
    • Callow, M.J., Verstuyft, J., Tangirala, R., Palinski, W., and Rubin, E.M. 1995. Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a). J. Clin. Invest. 96:1639-1646.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1639-1646
    • Callow, M.J.1    Verstuyft, J.2    Tangirala, R.3    Palinski, W.4    Rubin, E.M.5
  • 43
    • 0029920693 scopus 로고    scopus 로고
    • Lipoprotein lipase and lipolysis central roles in lipoprotein metabolism and atherogenesis
    • Goldberg, I.J. 1996. Lipoprotein lipase and lipolysis central roles in lipoprotein metabolism and atherogenesis. J. Lipid Res. 37:693-707.
    • (1996) J. Lipid Res. , vol.37 , pp. 693-707
    • Goldberg, I.J.1
  • 44
    • 0025836795 scopus 로고
    • Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions
    • Ylä-Herttuala, S., et al. 1991. Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. USA. 88:10143-10147.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10143-10147
    • Ylä-Herttuala, S.1
  • 46
    • 0027319417 scopus 로고
    • Early and persistent induction of monocyte chemoattractant protein 1 in rat cardiac allografts
    • Russell, M.E., et al. 1993. Early and persistent induction of monocyte chemoattractant protein 1 in rat cardiac allografts. Proc. Natl. Acad. Sci. USA. 90:6086-6090.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6086-6090
    • Russell, M.E.1


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