Association of rheumatoid arthritis with a functional chemokine receptor, CCR5

Arthritis and Rheumatism

Volumn 42, Issue 5, 1999, Pages 989-992

  Gómez Reino, Juan J ^a,b   Pablos, José L ^a   Carreira, Patricia E ^a   Santiago, BegoñA ^a   Serrano, Lourdes ^a   Vicario, Jose L ^c   Balsa, Alejandro ^d   Figueroa, Manuel ^e   De Juan, MaríA D ^e  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^c Ctro Trasfusiones Comunidad Madrid ^*  (Spain)

^d HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^e Hospital Nuestra Senora de Aranzazu   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5;

ARTICLE; GENE AMPLIFICATION; GENE DELETION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIUM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ALLELES; ARTHRITIS, RHEUMATOID; BASE PAIRING; GENOTYPE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MUTATION; RECEPTORS, CCR5;

EID: 0032959225     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199905)42:5<989::AID-ANR18>3.0.CO;2-U     Document Type: Article

References (15)

1. Ward SG, Bacon K, Westwick J. Chemokines and T lymphocytes: more than an attraction. Immunity 1998;9:1-9.
2. Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven transmembrane G protein-coupled receptor. Science 1996;272:872-7.
3. Cocchi F, De Vico AL, Garcino-Demo A, Arya SK, Gallo RC, Luso P. Identification of RANTES, MIP-1α, and MIP-1β as the major HIV-suppressive factors induced by CD8+ T cells. Science 1995;270:1811-5.
4. Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996;381:667-73.
5. Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, et al. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-5.
6. Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, et al. Homozygous defect in HIV-1 coreceptor account for resistance for some multiple-exposed individuals to HIV-1 infection. Cell 1996;86:367-77.
7. Bleu CC, Wu L, Hoxie JA, Springer TA, Mackay CR. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A 1997;94:1925-30.
8. Loetscher P, Seitz M, Baggiolini M, Moser B. Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J Exp Med 1996;184:569-77.
9. dim mature memory T cells that are potent helpers for B cell differentiation. Arthritis Rheum 1992;35:1455-65.
10. Kunkel SL, Lukacs N, Kasama T, Strieter RM. The role of chemokines in inflammatory joint disease. J Leukoc Biol 1996;59: 6-12.
11. Loetscher P, Uguccioni M, Bordoli L, Baggiolini M, Moser B. CCR5 is characteristic of Th1 lymphocytes. Nature 1998;391: 344-5.
12. Qui S, Rottman JB, Myers P, Kassam N, Weinblatt M, Loetscher M, et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 1998;101:746-54.
13. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
14. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
15. Hong-Gong J, Ratkay LG, Waterfield JD, Clark-Lewis I. An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-1pr mouse model. J Exp Med 1997;186: 131-7.