Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice

Journal of Vascular Surgery

Volumn 50, Issue 1, 2009, Pages 152-160

  Eefting, Daniël ^a,b   Bot, Ilze ^c   de Vries, Margreet R ^b   Schepers, Abbey ^a,b   van Bockel, J Hajo ^b   Van Berkel, Theo J C ^c   Biessen, Erik A L ^c,d   Quax, Paul H A ^b  

^a TNO   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E3; CHEMOKINE RECEPTOR CCR2; LENTIVIRAL SHORT HAIRPIN RNA; LENTIVIRUS VECTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CAROTID ARTERY; CELL MIGRATION; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG TARGETING; GENE SILENCING; GENE THERAPY; HYPERCHOLESTEROLEMIA; IN VITRO STUDY; IN VIVO STUDY; INFECTION; LENTIVIRINAE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SMOOTH MUSCLE FIBER; TREATMENT OUTCOME; VEIN GRAFT; VEIN GRAFT DISEASE; VEIN SURGERY; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; APOLIPOPROTEIN E3; ATHEROSCLEROSIS; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; GRAFT OCCLUSION, VASCULAR; HYPERCHOLESTEROLEMIA; LENTIVIRUS; MALE; MICE; RECEPTORS, CCR2; RNA INTERFERENCE; VEINS;

EID: 67649236757     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2009.03.027     Document Type: Article

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