The role of CC chemokine receptor 5 (CCR5) in islet allograft rejection

Diabetes

Volumn 51, Issue 8, 2002, Pages 2489-2495

  Abdi, Reza ^a   Neal Smith, R ^b   Makhlouf, Leila ^a   Najafian, Nader ^a   Luster, Andrew D ^b   Auchincloss Jr , Hugh ^b   Sayegh, Mohamed H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR5; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 5; STREPTOZOCIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; STREPTOZOCIN DIABETES; SURVIVAL TIME; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

EID: 0036325886     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.8.2489     Document Type: Article

References (30)

1. Chemokines: Chemotactic cytokines that mediate inflammation
2. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
3. Chemokines and leukocyte traffic
4. Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with a type 1 immune response
5. T helper 1 and T helper 2 cells respond differentially to chemokines
6. Monokine induced by IFN-gamma is a dominant factor directing T cells into murine cardiac allografts during acute rejection
7. Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: Blocking monocyte arrest and recruitment
8. Beneficial effects of targeting CCR 5 in allograft recipients
9. Expression of chemokines and chemokine receptors during human renal transplant rejection
10. Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation
11. CD28-independent costimulation of T cells in alloimmune responses
12. The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo
13. + T cells mediate rejection of porcine xenografts
14. CCR5 is characteristic of Th1 lymphocytes
15. Induction of chemokine gene expression during allogeneic skin graft rejection
16. Cxcr3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection
17. Donor-derived IP-10 initiates development of acute allograft rejection
18. Requirement of the chemokine receptor CXCR3 for acute allograft rejection
19. Th1/Th2 subsets: Distinct differences in homing and chemokine receptor expression?
20. Chemokines
21. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2S
22. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils
23. + T cell-mediated rejection of pancreatic islet allografts
24. + lymphocyte-associated Th2-type immune response in the intestine
25. The Th1/Th2 paradigm and the allograft response
26. Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo
27. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
28. Blocking the CD28-B7 T cell costimulation pathway induces long term cardiac allograft acceptance in the absence of IL-4
29. Cardiac allograft tolerance: Failure to develop in interleukin-4-deficient mice correlates with unusual allosensitization patterns
30. On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses