The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies

Neuroscience and Biobehavioral Reviews

Volumn 34, Issue 8, 2010, Pages 1307-1350

  Klinkenberg, Inge ^a   Blokland, Arjan ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Acetylcholine; Alzheimer's disease; Anxiety; Attention; Cognition; Learning; Memory; Model; Muscarinic M1; Sensory discrimination; Side effects; Signal detection

Indexed keywords

ACETYLCHOLINE; BIPERIDEN; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR AGONIST; MUSCARINIC M1 RECEPTOR ANTAGONIST; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; PIRENZEPINE; SCOPOLAMINE;

ANIMAL BEHAVIOR; ANXIETY; ASSOCIATION; ATTENTION; AVOIDANCE BEHAVIOR; BINDING AFFINITY; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONDITIONING; COORDINATION; DRUG EFFECT; ELECTROENCEPHALOGRAM; FEEDING BEHAVIOR; HUMAN; LATENT PERIOD; LEARNING; LOCOMOTION; MEMORY; MEMORY DISORDER; MENTAL PERFORMANCE; MENTAL TASK; MOTOR PERFORMANCE; MUSCLE FUNCTION; MYDRIASIS; NONHUMAN; PERCEPTIVE DISCRIMINATION; PLACE PREFERENCE; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; SALIVATION; SENSORY DYSFUNCTION; SHORT TERM MEMORY; SMOOTH MUSCLE; TASTE AVERSION; VALIDITY; VISUAL DISCRIMINATION; VISUAL STIMULATION; WORKING MEMORY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CHOLINERGIC ANTAGONISTS; COGNITION DISORDERS; DISCRIMINATION (PSYCHOLOGY); DISEASE MODELS, ANIMAL; HUMANS; LEARNING; LOCOMOTION; SCOPOLAMINE;

EID: 77954086949     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2010.04.001     Document Type: Review

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