-
1
-
-
0030945299
-
Muscarinic receptor subtype selective toxins
-
Adem A and Karlson E (1997) Muscarinic receptor subtype selective toxins. Life Sci 60:1069-1076.
-
(1997)
Life Sci
, vol.60
, pp. 1069-1076
-
-
Adem, A.1
Karlson, E.2
-
2
-
-
0023205408
-
An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover
-
Ashkenazi A, Winslow JW, Peralta EG, Peterson GL, Schimerlik MI, Capon DJ and Ramachandran J (1987) An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover. Science 238:672-675.
-
(1987)
Science
, vol.238
, pp. 672-675
-
-
Ashkenazi, A.1
Winslow, J.W.2
Peralta, E.G.3
Peterson, G.L.4
Schimerlik, M.I.5
Capon, D.J.6
Ramachandran, J.7
-
3
-
-
0027506471
-
The probable arrangement of the helices in G protein coupled receptors
-
Baldwin JM (1993) The probable arrangement of the helices in G protein coupled receptors. EMBO J 12:1693-1703.
-
(1993)
EMBO J
, vol.12
, pp. 1693-1703
-
-
Baldwin, J.M.1
-
4
-
-
0031565726
-
An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
-
Baldwin JM, Schertler GF and Unger VM (1997) An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors. J Mol Biol 272:144-164.
-
(1997)
J Mol Biol
, vol.272
, pp. 144-164
-
-
Baldwin, J.M.1
Schertler, G.F.2
Unger, V.M.3
-
5
-
-
0017107977
-
A comparison of affinity constants for muscarine-sensitive acetylcholine receptors in guinea-pig atrial pacemaker cells at 29°C and in ileum at 29°C and 37°C
-
Barlow RB, Berry KJ, Glenton PAM, Nikolau NM and Soh KS (1976) A comparison of affinity constants for muscarine-sensitive acetylcholine receptors in guinea-pig atrial pacemaker cells at 29°C and in ileum at 29°C and 37°C. Br J Pharmacol 58:613-620.
-
(1976)
Br J Pharmacol
, vol.58
, pp. 613-620
-
-
Barlow, R.B.1
Berry, K.J.2
Glenton, P.A.M.3
Nikolau, N.M.4
Soh, K.S.5
-
6
-
-
0026756764
-
Phenotypical characterization of the rat striatal neurons expressing muscarinic receptors
-
Bernard V, Normand E and Bloch B (1992) Phenotypical characterization of the rat striatal neurons expressing muscarinic receptors. J Neurosci 12:3591-3600.
-
(1992)
J Neurosci
, vol.12
, pp. 3591-3600
-
-
Bernard, V.1
Normand, E.2
Bloch, B.3
-
8
-
-
0030902106
-
Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes
-
Birdsall NJM, Farries T, Gharagozloo P, Kobayashi S, Kuonen D, Lazareno S, Popham A and Sugimoto M (1997) Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes. Lift Sci 60:1047-1052.
-
(1997)
Lift Sci
, vol.60
, pp. 1047-1052
-
-
Birdsall, N.J.M.1
Farries, T.2
Gharagozloo, P.3
Kobayashi, S.4
Kuonen, D.5
Lazareno, S.6
Popham, A.7
Sugimoto, M.8
-
11
-
-
0029059732
-
q/11 by the m3 muscarinic acetylcholine receptor
-
q/11 by the m3 muscarinic acetylcholine receptor. J Biol Chem 270:17741-17748.
-
(1995)
J Biol Chem
, vol.270
, pp. 17741-17748
-
-
Blin, N.1
Yun, J.2
Wess, J.3
-
12
-
-
0028291618
-
Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors
-
Blüml K, Mutschler E and Wess J (1994) Functional role in ligand binding and receptor activation of an asparagine residue present in the sixth transmembrane domain of all muscarinic acetylcholine receptors. J Biol Chem 269:18870-18876.
-
(1994)
J Biol Chem
, vol.269
, pp. 18870-18876
-
-
Blüml, K.1
Mutschler, E.2
Wess, J.3
-
14
-
-
0023191072
-
Identification of a family of muscarinic acetylcholine receptor genes
-
Bonner TI, Buckley NJ, Young AC and Brann MR (1987) Identification of a family of muscarinic acetylcholine receptor genes. Science 237:527-532.
-
(1987)
Science
, vol.237
, pp. 527-532
-
-
Bonner, T.I.1
Buckley, N.J.2
Young, A.C.3
Brann, M.R.4
-
15
-
-
0000954990
-
Chromosomal mapping of the five human genes encoding muscarinic acetylcholine receptors
-
Bonner TI, Modi WS, Seuanez HN, O'Brien SJ (1991) Chromosomal mapping of the five human genes encoding muscarinic acetylcholine receptors. Cytogenet Cell Genet 58:1850-1851.
-
(1991)
Cytogenet Cell Genet
, vol.58
, pp. 1850-1851
-
-
Bonner, T.I.1
Modi, W.S.2
Seuanez, H.N.3
O'Brien, S.J.4
-
16
-
-
0024039146
-
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes
-
Bonner TI, Young AC, Brann MR and Buckley NJ (1988) Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron 1:403-410.
-
(1988)
Neuron
, vol.1
, pp. 403-410
-
-
Bonner, T.I.1
Young, A.C.2
Brann, M.R.3
Buckley, N.J.4
-
17
-
-
0002170688
-
+ channels
-
Wess J ed R. G. Landes, Austin
-
+ channels, in Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function (Wess J ed) pp 165 182, R. G. Landes, Austin.
-
(1995)
Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function
, pp. 165
-
-
Brown, D.A.1
Buckley, N.J.2
Caulfield, M.P.3
Duffy, S.M.4
Jones, S.5
Lamas, J.A.6
Marsh, S.J.7
Robbins, J.8
Selyanko, A.A.9
-
18
-
-
0019162104
-
Antagonist discrimination between ganglionic and ileal muscarinic receptors
-
Brown DA, Forward A and Marsh S (1980) Antagonist discrimination between ganglionic and ileal muscarinic receptors. Br J Pharmacol 71:362-364.
-
(1980)
Br J Pharmacol
, vol.71
, pp. 362-364
-
-
Brown, D.A.1
Forward, A.2
Marsh, S.3
-
19
-
-
0024507616
-
Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells
-
Buckley NJ, Bonner TI, Buckley CM and Brann MR (1989) Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. Mol Pharmacol 35:469-476.
-
(1989)
Mol Pharmacol
, vol.35
, pp. 469-476
-
-
Buckley, N.J.1
Bonner, T.I.2
Buckley, C.M.3
Brann, M.R.4
-
20
-
-
0031037633
-
Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins
-
Burstein ES, Spalding TA and Brann MR (1997) Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins. Mol Pharmacol 51:312-319.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 312-319
-
-
Burstein, E.S.1
Spalding, T.A.2
Brann, M.R.3
-
22
-
-
0001823550
-
Muscarinic receptor classification
-
Eglen RM ed CRC Press, New York
-
Caulfield MP (1997) Muscarinic receptor classification, in Muscarinic Receptor Subtypes in Smooth Muscle (Eglen RM ed) pp 1-37, CRC Press, New York.
-
(1997)
Muscarinic Receptor Subtypes in Smooth Muscle
, pp. 1-37
-
-
Caulfield, M.P.1
-
23
-
-
0027208248
-
Muscarinic receptors: Characterization, coupling and function
-
Caulfield MP (1993) Muscarinic receptors: Characterization, coupling and function. Pharmacol Ther 58:319-379.
-
(1993)
Pharmacol Ther
, vol.58
, pp. 319-379
-
-
Caulfield, M.P.1
-
24
-
-
0017105216
-
The inhibitory effect of gallamine on muscarinic receptors
-
Clark AL and Mitchelson F (1976) The inhibitory effect of gallamine on muscarinic receptors. Br J Pharmacol 58:323-331.
-
(1976)
Br J Pharmacol
, vol.58
, pp. 323-331
-
-
Clark, A.L.1
Mitchelson, F.2
-
25
-
-
7144251050
-
Over-expression and purification of engineered M1 muscarinic receptors
-
Curtis CAM and Hulme EC (1997) Over-expression and purification of engineered M1 muscarinic receptors (abstract). Life Sci 60:1176.
-
(1997)
Life Sci
, vol.60
, pp. 1176
-
-
Curtis, C.A.M.1
Hulme, E.C.2
-
26
-
-
0024492790
-
Propylbenzilylcholine mustard labels an acidic residue in transmembrane helix 3 of the muscarinic receptor
-
Curtis CA, Wheatley M, Bansal S, Birdsall NJM, Eveleigh P, Pedder EK, Poyner D and Hulme EC (1989) Propylbenzilylcholine mustard labels an acidic residue in transmembrane helix 3 of the muscarinic receptor (abstract). J Biol Chem 264: 489-495.
-
(1989)
J Biol Chem
, vol.264
, pp. 489-495
-
-
Curtis, C.A.1
Wheatley, M.2
Bansal, S.3
Birdsall, N.J.M.4
Eveleigh, P.5
Pedder, E.K.6
Poyner, D.7
Hulme, E.C.8
-
27
-
-
0026524116
-
Prejunctional muscarine receptors in the rabbit ear artery differ from M1, M2 and M3 muscarine receptors
-
Darroch SA, Choo LK and Mitchelson F (1992) Prejunctional muscarine receptors in the rabbit ear artery differ from M1, M2 and M3 muscarine receptors. Naunyn Schmiedebergs Arch Pharmacol 345:288-295.
-
(1992)
Naunyn Schmiedebergs Arch Pharmacol
, vol.345
, pp. 288-295
-
-
Darroch, S.A.1
Choo, L.K.2
Mitchelson, F.3
-
28
-
-
0027976926
-
A novel mechanism for coupling of m4 muscarinic acetylcholine receptors to calmodulin-sensitive adenylyl cyclases: Crossover from G protein-coupled inhibition to stimulation
-
Dittman AH, Weber JP, Hinds TR, Choi E-J, Migeon JC, Nathanson NM and Storm DR (1994) A novel mechanism for coupling of m4 muscarinic acetylcholine receptors to calmodulin-sensitive adenylyl cyclases: Crossover from G protein-coupled inhibition to stimulation. Biochemistry 33:943-951.
-
(1994)
Biochemistry
, vol.33
, pp. 943-951
-
-
Dittman, A.H.1
Weber, J.P.2
Hinds, T.R.3
Choi, E.-J.4
Migeon, J.C.5
Nathanson, N.M.6
Sto, D.R.7
-
29
-
-
0026050428
-
Immunological detection of muscarinic receptor subtype proteins (m1-m5) in rabbit peripheral tissues
-
Dörje F, Levey A and Brenn MR (1991a) Immunological detection of muscarinic receptor subtype proteins (m1-m5) in rabbit peripheral tissues. Mol Pharmacol 40:459-462.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 459-462
-
-
Dörje, F.1
Levey, A.2
Brenn, M.R.3
-
30
-
-
0026033504
-
Antagonist binding profiles of five cloned human muscarinic receptor subtypes
-
Dörje F, Wess J, Lambrecht G, Tacke R, Mutschler E and Brann MR (1991b) Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther 256:727-733.
-
(1991)
J Pharmacol Exp Ther
, vol.256
, pp. 727-733
-
-
Dörje, F.1
Wess, J.2
Lambrecht, G.3
Tacke, R.4
Mutschler, E.5
Brann, M.R.6
-
31
-
-
0030442725
-
Muscarinic receptor subtypes and smooth muscle function
-
Eglen RM, Hegde SS and Watson N (1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev 48:531-565.
-
(1996)
Pharmacol Rev
, vol.48
, pp. 531-565
-
-
Eglen, R.M.1
Hegde, S.S.2
Watson, N.3
-
33
-
-
0025180022
-
Heterogeneity of vascular muscarinic receptors
-
Eglen RM and Whiting RL (1990) Heterogeneity of vascular muscarinic receptors. J Auton Pharmacol 10:233-245.
-
(1990)
J Auton Pharmacol
, vol.10
, pp. 233-245
-
-
Eglen, R.M.1
Whiting, R.L.2
-
34
-
-
0030052086
-
Selective muscarinic receptor agonists and antagonists
-
Eglen RM and Whiting RL (1996) Selective muscarinic receptor agonists and antagonists. Pharmacol Toxicol 78:59-78.
-
(1996)
Pharmacol Toxicol
, vol.78
, pp. 59-78
-
-
Eglen, R.M.1
Whiting, R.L.2
-
35
-
-
0023794328
-
Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium
-
Ehlert FJ (1988) Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium. J Pharmacol Exp Ther 247:596-602.
-
(1988)
J Pharmacol Exp Ther
, vol.247
, pp. 596-602
-
-
Ehlert, F.J.1
-
36
-
-
0026005728
-
Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes
-
Ellis J, Huyler J and Brann MR (1991) Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes. Biochem Pharmacol 42:199-205.
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 199-205
-
-
Ellis, J.1
Huyler, J.2
Brann, M.R.3
-
37
-
-
0027172276
-
Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions
-
Ellis J, Seidenberg M and Brann MR (1993) Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions. Mol Pharmacol 44:583-588.
-
(1993)
Mol Pharmacol
, vol.44
, pp. 583-588
-
-
Ellis, J.1
Seidenberg, M.2
Brann, M.R.3
-
38
-
-
0023821640
-
Muscarinic M1- and M2-receptors mediating opposite effects on neuromuscular transmission in rabbit vas deferens
-
Eltze M (1988) Muscarinic M1- and M2-receptors mediating opposite effects on neuromuscular transmission in rabbit vas deferens. Eur J Pharmacol 151:205-221.
-
(1988)
Eur J Pharmacol
, vol.151
, pp. 205-221
-
-
Eltze, M.1
-
39
-
-
0027396773
-
WAL 2014: A muscarinic agonist with preferential neuron-stimulating properties
-
Ensinger HA, Doods HN, Immel-Sehr AR, Kuhn FJ, Lambrecht G, Mendla KD, Muller RE, Mutschler E, Sagrada A, Walther G and Hammer R (1993) WAL 2014: A muscarinic agonist with preferential neuron-stimulating properties. Life Sci 52:473-480.
-
(1993)
Life Sci
, vol.52
, pp. 473-480
-
-
Ensinger, H.A.1
Doods, H.N.2
Immel-Sehr, A.R.3
Kuhn, F.J.4
Lambrecht, G.5
Mendla, K.D.6
Muller, R.E.7
Mutschler, E.8
Sagrada, A.9
Walther, G.10
Hammer, R.11
-
40
-
-
0029013930
-
Muscarinic acetylcholine receptors: Signal transduction through multiple effectors
-
Felder CC (1995) Muscarinic acetylcholine receptors: Signal transduction through multiple effectors. FASEB J 9:619-625.
-
(1995)
FASEB J
, vol.9
, pp. 619-625
-
-
Felder, C.C.1
-
41
-
-
9344262345
-
1 agonists in the treatment of Alzheimer's disease: Novel properties and clinical update
-
1 agonists in the treatment of Alzheimer's disease: Novel properties and clinical update. Ann N Y Acad Sci 777:189-196.
-
(1996)
Ann N Y Acad Sci
, vol.777
, pp. 189-196
-
-
Fisher, A.1
Heldman, E.2
Gurwitz, D.3
Haring, R.4
Karton, Y.5
Mesulam, H.6
Pittel, Z.7
Marciano, D.8
Brandeis, R.9
Sadot, E.10
Barg, Y.11
Pinkas-Kramarski, R.12
Vogel, Z.13
Ginzburg, I.14
Treves, T.A.15
Verchovsky, R.16
Klimowsky, S.17
Korczyn, A.D.18
-
42
-
-
0030990069
-
Pharmacological strategies to selectively label and localize muscarinic receptor subtypes
-
Flynn DD, Reever CM and Ferrari-Dileo G (1995) Pharmacological strategies to selectively label and localize muscarinic receptor subtypes Drug Dev Res 40:104-116.
-
(1995)
Drug Dev Res
, vol.40
, pp. 104-116
-
-
Flynn, D.D.1
Reever, C.M.2
Ferrari-Dileo, G.3
-
43
-
-
0027509178
-
The design of novel partial muscarinic agonists that have functional selectivity in pharmacological preparations in vitro and reduced side-effect profile in vivo
-
Freedman SB, Dawson GR, Iversen LL, Baker R and Hargreaves RJ (1993) The design of novel partial muscarinic agonists that have functional selectivity in pharmacological preparations in vitro and reduced side-effect profile in vivo. Life Sci 52:489-495.
-
(1993)
Life Sci
, vol.52
, pp. 489-495
-
-
Freedman, S.B.1
Dawson, G.R.2
Iversen, L.L.3
Baker, R.4
Hargreaves, R.J.5
-
44
-
-
0029107583
-
Heteroreceptor-mediated modulation of noradrenaline and acetylcholine release from peripheral nerves
-
Fuder H and Muscholl E (1995) Heteroreceptor-mediated modulation of noradrenaline and acetylcholine release from peripheral nerves. Rev Physiol Biochem Pharmacol 126:265-412.
-
(1995)
Rev Physiol Biochem Pharmacol
, vol.126
, pp. 265-412
-
-
Fuder, H.1
Muscholl, E.2
-
45
-
-
0027330204
-
1 muscarinic receptors increase calcium current and phosphoinositide turnover in guinea-pig ventricular cardiocytes
-
1 muscarinic receptors increase calcium current and phosphoinositide turnover in guinea-pig ventricular cardiocytes. J Physiol 471:41-60.
-
(1993)
J Physiol
, vol.471
, pp. 41-60
-
-
Gallo, M.P.1
Alloatti, G.2
Eva, C.3
Oberto, A.4
Levi, R.C.5
-
46
-
-
0028069686
-
Characterisation of the prejunctional muscarinic receptors mediating inhibition of evoked release of endogenous noradrenaline in the rabbit vas deferens
-
Grimm U, Fuder H, Moser U, Bäumert HG, Mutschler E and Lambrecht G (1994a) Characterisation of the prejunctional muscarinic receptors mediating inhibition of evoked release of endogenous noradrenaline in the rabbit vas deferens. Naunyn Schmiedebergs Arch Pharmacol 349:1-10.
-
(1994)
Naunyn Schmiedebergs Arch Pharmacol
, vol.349
, pp. 1-10
-
-
Grimm, U.1
Fuder, H.2
Moser, U.3
Bäumert, H.G.4
Mutschler, E.5
Lambrecht, G.6
-
47
-
-
0028080244
-
Muscarinic receptors: Focus on presynaptic mechanisms and recently developed novel agonists and antagonists
-
Grimm U, Moser U, Mutschler E and Lambrecht G (1994b) Muscarinic receptors: Focus on presynaptic mechanisms and recently developed novel agonists and antagonists. Pharmazie 49:711-726.
-
(1994)
Pharmazie
, vol.49
, pp. 711-726
-
-
Grimm, U.1
Moser, U.2
Mutschler, E.3
Lambrecht, G.4
-
49
-
-
0027950411
-
Discrete activation of transduction pathways associated with acetylcholine m1 receptor by aeveral muscarinic ligands
-
Gurwitz D, Haring R, Heldman E, Fraser CM, Manor D and Fisher A (1994) Discrete activation of transduction pathways associated with acetylcholine m1 receptor by aeveral muscarinic ligands. Eur J Pharmacol 267:21-31.
-
(1994)
Eur J Pharmacol
, vol.267
, pp. 21-31
-
-
Gurwitz, D.1
Haring, R.2
Heldman, E.3
Fraser, C.M.4
Manor, D.5
Fisher, A.6
-
51
-
-
0030708762
-
Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice
-
Hamilton SE, Loose MD, Qi M, Levey AI, Hille B, McNight GS, Idzerda RL and Nathanson NM (1997) Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proc Natl Acad Sci USA 94:13311-13316.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13311-13316
-
-
Hamilton, S.E.1
Loose, M.D.2
Qi, M.3
Levey, A.I.4
Hille, B.5
McNight, G.S.6
Idzerda, R.L.7
Nathanson, N.M.8
-
52
-
-
0018835992
-
Pirenzepine distinguishes between subclasses of muscarinic receptors
-
Hammer R, Berrie CP, Birdsall NJM, Burgen ASV and Hulme EC (1980) Pirenzepine distinguishes between subclasses of muscarinic receptors. Nature 283:90-92.
-
(1980)
Nature
, vol.283
, pp. 90-92
-
-
Hammer, R.1
Berrie, C.P.2
Birdsall, N.J.M.3
Burgen, A.S.V.4
Hulme, E.C.5
-
53
-
-
0020421340
-
2 biochemical and functional characterization
-
2 biochemical and functional characterization. Life Sci 31:2991-2998.
-
(1983)
Life Sci
, vol.31
, pp. 2991-2998
-
-
Hammer, R.1
Giachetti, A.2
-
54
-
-
0031569809
-
Palmitoylation of muscarinic acetylcholine receptor m2 subtypes: Reduction in their ability to activate G proteins by mutation of a putative palmitoylation site, cysteine 457, in the carboxyl-terminal tail
-
Hayashi MK and Haga T (1997) Palmitoylation of muscarinic acetylcholine receptor m2 subtypes: Reduction in their ability to activate G proteins by mutation of a putative palmitoylation site, cysteine 457, in the carboxyl-terminal tail. Arch Biochem Biophys 340:376-382.
-
(1997)
Arch Biochem Biophys
, vol.340
, pp. 376-382
-
-
Hayashi, M.K.1
Haga, T.2
-
55
-
-
0025292355
-
Model for the structure of bacteriorhodopsin based on high-resolution electron cryomicroscopy
-
Henderson R, Baldwin JM, Ceska TA, Zemlin F, Beckmann E and Downing KH (1990) Model for the structure of bacteriorhodopsin based on high-resolution electron cryomicroscopy. J Mol Biol 213:899-929.
-
(1990)
J Mol Biol
, vol.213
, pp. 899-929
-
-
Henderson, R.1
Baldwin, J.M.2
Ceska, T.A.3
Zemlin, F.4
Beckmann, E.5
Downing, K.H.6
-
56
-
-
0030066476
-
Functional importance of the amino terminus of Gq alpha
-
Hepler JR, Biddlecombe GH, Kleuss C, Camp LA, Hofmann SL, Ross EM and Gilman AG (1996) Functional importance of the amino terminus of Gq alpha. J Biol Chem 271:496-504.
-
(1996)
J Biol Chem
, vol.271
, pp. 496-504
-
-
Hepler, J.R.1
Biddlecombe, G.H.2
Kleuss, C.3
Camp, L.A.4
Hofmann, S.L.5
Ross, E.M.6
Gilman, A.G.7
-
57
-
-
0028124243
-
Cloning of a Xenopus laevis muscarinic receptor encoded by an intronless gene
-
Herrera L, Carvallo P, Antonelli M and Olate J (1994) Cloning of a Xenopus laevis muscarinic receptor encoded by an intronless gene. FEBS Lett 352:175-179.
-
(1994)
FEBS Lett
, vol.352
, pp. 175-179
-
-
Herrera, L.1
Carvallo, P.2
Antonelli, M.3
Olate, J.4
-
58
-
-
0028922996
-
Diverse pre- and post-synaptic expression of m1-m4 muscarinic receptor proteins in neurons and afferents in the rat neostriatum
-
Hersch SM and Levey AI (1995) Diverse pre- and post-synaptic expression of m1-m4 muscarinic receptor proteins in neurons and afferents in the rat neostriatum. Life Sci 56:931-938.
-
(1995)
Life Sci
, vol.56
, pp. 931-938
-
-
Hersch, S.M.1
Levey, A.I.2
-
59
-
-
0029960329
-
Influence of monovalent cations on the binding of a charged and an uncharged ('carbo') muscarinic antagonist to muscarinic receptors
-
Hon X, Wehrle J, Menge W, Ciccarelli E, Wess J, Mutschler E, Lambrecht G, Timmerman H and Waelbroeck M (1996) Influence of monovalent cations on the binding of a charged and an uncharged ('carbo') muscarinic antagonist to muscarinic receptors. Br J Pharmacol 117:955-961.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 955-961
-
-
Hon, X.1
Wehrle, J.2
Menge, W.3
Ciccarelli, E.4
Wess, J.5
Mutschler, E.6
Lambrecht, G.7
Timmerman, H.8
Waelbroeck, M.9
-
60
-
-
0026563171
-
Functional expression of rat M5 muscarinic acetylcholine receptor in yeast
-
Huang HJ, Liao CF, Yang BC and Kuo TT (1992) Functional expression of rat M5 muscarinic acetylcholine receptor in yeast. Biochem Biophys Res Commun 182: 1180-1186.
-
(1992)
Biochem Biophys Res Commun
, vol.182
, pp. 1180-1186
-
-
Huang, H.J.1
Liao, C.F.2
Yang, B.C.3
Kuo, T.T.4
-
62
-
-
0002867860
-
Strategy and tactics in receptor binding studies
-
Hulme EC ed Oxford University Press, New York
-
Hulme EC and Birdsall NJM (1992) Strategy and tactics in receptor binding studies, in Receptor Ligand Interactions: A Practical Approach (Hulme EC ed) pp 63-176, Oxford University Press, New York.
-
(1992)
Receptor Ligand Interactions: A Practical Approach
, pp. 63-176
-
-
Hulme, E.C.1
Birdsall, N.J.M.2
-
64
-
-
0028909699
-
In vitro and in vivo evaluation of the subtype-selective agonist PD 151832
-
Jaen J, Barrett S, Brann M, Callahan M, Davis R, Doyle P, Eubanks D, Lauffer L, Lipinski W, Moreland D, Nelson C, Raby C, Schwarz R, Spencer C and Tecle H (1995) In vitro and in vivo evaluation of the subtype-selective agonist PD 151832. Life Sci 56:845-852.
-
(1995)
Life Sci
, vol.56
, pp. 845-852
-
-
Jaen, J.1
Barrett, S.2
Brann, M.3
Callahan, M.4
Davis, R.5
Doyle, P.6
Eubanks, D.7
Lauffer, L.8
Lipinski, W.9
Moreland, D.10
Nelson, C.11
Raby, C.12
Schwarz, R.13
Spencer, C.14
Tecle, H.15
-
65
-
-
1842333847
-
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic receptors
-
Jakubik J, Bacakova L, El-Fakahany EE and Tucek S (1997) Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic receptors. Mol Pharmacol 52:172-179.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 172-179
-
-
Jakubik, J.1
Bacakova, L.2
El-Fakahany, E.E.3
Tucek, S.4
-
66
-
-
0027973761
-
Toxins from mamba venoms: Small proteins with selectivities for different subtypes of muscarinic acetylcholine receptors
-
Jerusalinsky D and Harvey AL (1994) Toxins from mamba venoms: Small proteins with selectivities for different subtypes of muscarinic acetylcholine receptors. Trends Pharmacol Sci 15:424-430.
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 424-430
-
-
Jerusalinsky, D.1
Harvey, A.L.2
-
67
-
-
0027930116
-
A toxin from the green mamba Dendroaspis angusticeps: Amino acid sequence and selectivity for muscarinic m4 receptors
-
Jolkkonen M, Van Giersbergen PLM, Hellman U, Wernstedt C and Karlsson E (1994) A toxin from the green mamba Dendroaspis angusticeps: Amino acid sequence and selectivity for muscarinic m4 receptors. FEBS Lett 352:91-94.
-
(1994)
FEBS Lett
, vol.352
, pp. 91-94
-
-
Jolkkonen, M.1
VanGiersbergen, P.L.M.2
Hellman, U.3
Wernstedt, C.4
Karlsson, E.5
-
69
-
-
0029812311
-
The classification of seven transmembrane receptors in recombinant expression systems
-
Kenakin TP (1996) The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol Rev 48:413-463.
-
(1996)
Pharmacol Rev
, vol.48
, pp. 413-463
-
-
Kenakin, T.P.1
-
70
-
-
0025008440
-
Promiscuous or heterogeneous muscarinic receptors in rat atria? I. Schild analysis with simple competitive antagonists
-
Kenakin TP and Boselli C (1990) Promiscuous or heterogeneous muscarinic receptors in rat atria? I. Schild analysis with simple competitive antagonists. Eur J Pharmacol 191:39-48.
-
(1990)
Eur J Pharmacol
, vol.191
, pp. 39-48
-
-
Kenakin, T.P.1
Boselli, C.2
-
72
-
-
0023040350
-
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor
-
Kubo T, Fukuda K, Mikami A, Maeda A, Takahashi H, Mishina M, Haga T, Haga K, Ichiyama A, Kangawa K, Kojima M, Matsuo H, Hirose T and Numa S (1986a) Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature 323:411-416.
-
(1986)
Nature
, vol.323
, pp. 411-416
-
-
Kubo, T.1
Fukuda, K.2
Mikami, A.3
Maeda, A.4
Takahashi, H.5
Mishina, M.6
Haga, T.7
Haga, K.8
Ichiyama, A.9
Kangawa, K.10
Kojima, M.11
Matsuo, H.12
Hirose, T.13
Numa, S.14
-
73
-
-
0022919827
-
Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence
-
Kubo T, Maeda A, Sugimoto K, Akiba I, Mikami A, Takahashi H, Haga T, Haga K, Ichiyama A, Kangawa K, Matsuo H, Hirose T and Numa S (1986b) Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence. FEBS Lett 209:367-372.
-
(1986)
FEBS Lett
, vol.209
, pp. 367-372
-
-
Kubo, T.1
Maeda, A.2
Sugimoto, K.3
Akiba, I.4
Mikami, A.5
Takahashi, H.6
Haga, T.7
Haga, K.8
Ichiyama, A.9
Kangawa, K.10
Matsuo, H.11
Hirose, T.12
Numa, S.13
-
74
-
-
0025121206
-
Muscarinic acetylcholine receptors: Peptide sequencing identifies residues involved in antagonist binding and disulfide bond formation
-
Kurtenbach E, Curtis CA, Pedder EK, Aitken A, Harris AC and Hulme EC (1990) Muscarinic acetylcholine receptors: Peptide sequencing identifies residues involved in antagonist binding and disulfide bond formation. J Biol Chem 265: 13702-13708.
-
(1990)
J Biol Chem
, vol.265
, pp. 13702-13708
-
-
Kurtenbach, E.1
Curtis, C.A.2
Pedder, E.K.3
Aitken, A.4
Harris, A.C.5
Hulme, E.C.6
-
75
-
-
0027393707
-
New functionally selective muscarinic agonists
-
Lambrecht G, Moser U, Grimm U, Hermann U, Hilderbrandt C, Waelbroeck M, Christophe J and Mutschler E (1993) New functionally selective muscarinic agonists. Life Sci 52:481-486.
-
(1993)
Life Sci
, vol.52
, pp. 481-486
-
-
Lambrecht, G.1
Moser, U.2
Grimm, U.3
Hermann, U.4
Hilderbrandt, C.5
Waelbroeck, M.6
Christophe, J.7
Mutschler, E.8
-
76
-
-
7144255378
-
Stereoselective interaction of p-fluoro-trihexyphenidyl and its methiodide with four muscarinic receptor subtypes
-
Lambrecht G, Pfaff O, Aasen AJ, Sjö P, Mutschler E and Waelbroeck M (1997) Stereoselective interaction of p-fluoro-trihexyphenidyl and its methiodide with four muscarinic receptor subtypes (abstract). Life Sci 60:1166.
-
(1997)
Life Sci
, vol.60
, pp. 1166
-
-
Lambrecht, G.1
Pfaff, O.2
Aasen, A.J.3
Sjö, P.4
Mutschler, E.5
Waelbroeck, M.6
-
77
-
-
0029126526
-
Detection, quantitation and verification of allosteric interactions of agents with labelled and unlabelled ligands at G protein-coupled receptors: Interactions of strychnine and acetylcholine at muscarinic receptors
-
Lazareno S and Birdsall NJM (1995) Detection, quantitation and verification of allosteric interactions of agents with labelled and unlabelled ligands at G protein-coupled receptors: Interactions of strychnine and acetylcholine at muscarinic receptors. Mol Pharmacol 48:362-378.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 362-378
-
-
Lazareno, S.1
Birdsall, N.J.M.2
-
78
-
-
0027170155
-
Estimation of competitive antagonist affinity from functional inhibition curves using the Gaddum, Schild and Cheng-Prusoff equations
-
Lazareno S and Birdsall NJM (1993a) Estimation of competitive antagonist affinity from functional inhibition curves using the Gaddum, Schild and Cheng-Prusoff equations. Br J Pharmacol 109:1110-1119.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 1110-1119
-
-
Lazareno, S.1
Birdsall, N.J.M.2
-
79
-
-
0027313323
-
35s]-Gtpgammas binding mediated by human muscarinic m1-m4 receptors: Antagonist studies
-
35s]-Gtpgammas binding mediated by human muscarinic m1-m4 receptors: Antagonist studies. Br J Pharmacol 109:1120-1127.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 1120-1127
-
-
Lazareno, S.1
Birdsall, N.J.M.2
-
81
-
-
0027525822
-
Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors M1-M4
-
Lazareno S, Farries T and Birdsall NJM (1993) Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors M1-M4. Life Sci 52:449-456.
-
(1993)
Life Sci
, vol.52
, pp. 449-456
-
-
Lazareno, S.1
Farries, T.2
Birdsall, N.J.M.3
-
82
-
-
0031978756
-
Subtype selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: Radioligand binding studies
-
Lazareno S, Gharagozloo P, Kuonen D, Popham A and Birdsall NJM (1998) Subtype selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: Radioligand binding studies. Mol Pharmacol, 53:573-589.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 573-589
-
-
Lazareno, S.1
Gharagozloo, P.2
Kuonen, D.3
Popham, A.4
Birdsall, N.J.M.5
-
83
-
-
0025875643
-
Allosteric antagonists of the muscarinic acetylcholine receptor
-
Lee NH and El-Fakahany EE (1991) Allosteric antagonists of the muscarinic acetylcholine receptor. Biochem Pharmacol 42:199-205.
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 199-205
-
-
Lee, N.H.1
El-Fakahany, E.E.2
-
84
-
-
0028241381
-
Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor
-
Leppik RA, Miller RC, Eck M and Pacquet J-L (1994) Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor. Mol Pharmacol 45:983-990.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 983-990
-
-
Leppik, R.A.1
Miller, R.C.2
Eck, M.3
Pacquet, J.-L.4
-
85
-
-
0027465882
-
Immunological localization of m1-m5 muscarinic receptor subtypes in peripheral tissues and brain
-
Levey AI (1993) Immunological localization of m1-m5 muscarinic receptor subtypes in peripheral tissues and brain. Life Sci 52:441-448.
-
(1993)
Life Sci
, vol.52
, pp. 441-448
-
-
Levey, A.I.1
-
86
-
-
9044229994
-
Subtypes of muscarinic receptors: Proceedings of the 4th international symposium on subtypes of muscarinic receptors
-
Levine RR and Birdsall NJM (eds) (1989) Subtypes of muscarinic receptors: Proceedings of the 4th international symposium on subtypes of muscarinic receptors. Trends Pharmacol Sci 10(Suppl 7):S1-S119.
-
(1989)
Trends Pharmacol Sci
, vol.10
, Issue.7 SUPPL.
-
-
Levine, R.R.1
Birdsall, N.J.M.2
-
87
-
-
0008712644
-
Subtypes of muscarinic receptors. Proceedings of the 7th international symposium on subtypes of muscarinic receptors
-
Levine RR and Birdsall NJM (eds) (1997) Subtypes of muscarinic receptors. Proceedings of the 7th international symposium on subtypes of muscarinic receptors. Life Sci 60:963-1207.
-
(1997)
Life Sci
, vol.60
, pp. 963-1207
-
-
Levine, R.R.1
Birdsall, N.J.M.2
-
88
-
-
0025837511
-
Distribution of m2 muscarinic receptors in rat brain using antisera selective for m2 receptors
-
Li M, Yasuda RP, Wall SJ, Wellstein A and Wolfe BB (1991) Distribution of m2 muscarinic receptors in rat brain using antisera selective for m2 receptors. Mol Pharmacol 40:28-35.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 28-35
-
-
Li, M.1
Yasuda, R.P.2
Wall, S.J.3
Wellstein, A.4
Wolfe, B.B.5
-
89
-
-
0029589916
-
Identification of a receptor/G protein contact site critical for signaling specificity and G protein activation
-
Liu J, Conklin BR, Blin N, Yun J and Wess J (1995) Identification of a receptor/G protein contact site critical for signaling specificity and G protein activation. Proc Natl Acad Sci USA 92:11642-11646.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11642-11646
-
-
Liu, J.1
Conklin, B.R.2
Blin, N.3
Yun, J.4
Wess, J.5
-
90
-
-
0031037632
-
The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: Mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling
-
Lu Z-L, Curtis CA, Jones PG, Pavia J and Hulme EC (1997) The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: Mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling. Mol Pharmacol 51:234-241.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 234-241
-
-
Lu, Z.-L.1
Curtis, C.A.2
Jones, P.G.3
Pavia, J.4
Hulme, E.C.5
-
91
-
-
0028169674
-
Binding profile of the selective muscarinic receptor antagonist tripitramine
-
Maggio R, Barbier P, Bolognesi ML, Minarini A, Tedeschi D and Melchiorre C (1994) Binding profile of the selective muscarinic receptor antagonist tripitramine. Eur J Pharmacol 268:459-462.
-
(1994)
Eur J Pharmacol
, vol.268
, pp. 459-462
-
-
Maggio, R.1
Barbier, P.2
Bolognesi, M.L.3
Minarini, A.4
Tedeschi, D.5
Melchiorre, C.6
-
92
-
-
0024452012
-
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype
-
Marrion NV, Smart TG, Marsh SJ and Brown DA (1989) Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype. Br J Pharmacol 98:557-573.
-
(1989)
Br J Pharmacol
, vol.98
, pp. 557-573
-
-
Marrion, N.V.1
Smart, T.G.2
Marsh, S.J.3
Brown, D.A.4
-
93
-
-
0029153856
-
Synergistic regulation of a neuronal chloride current by intracellular calcium and muscarinic receptor activation: A role for protein kinase C
-
Marsh SJ, Trouslard J, Leaney J and Brown DA (1995) Synergistic regulation of a neuronal chloride current by intracellular calcium and muscarinic receptor activation: A role for protein kinase C. Neuron 15:729-737.
-
(1995)
Neuron
, vol.15
, pp. 729-737
-
-
Marsh, S.J.1
Trouslard, J.2
Leaney, J.3
Brown, D.A.4
-
94
-
-
0028815463
-
Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis
-
Matsui H, Lazareno S and Birdsall NJM (1995) Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis. Mol Pharmacol 47:88-98.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 88-98
-
-
Matsui, H.1
Lazareno, S.2
Birdsall, N.J.M.3
-
95
-
-
0342894679
-
Muscarinic regulation of the L-type calcium current in isolated cardiac myocytes
-
Méry P-F, Abi-Gerges N, Nandecasteele G, Jurevicius J, Eschenhagen T and Fischmeister R (1997) Muscarinic regulation of the L-type calcium current in isolated cardiac myocytes. Life Sci 60:1113-1120.
-
(1997)
Life Sci
, vol.60
, pp. 1113-1120
-
-
Méry, P.-F.1
Abi-Gerges, N.2
Nandecasteele, G.3
Jurevicius, J.4
Eschenhagen, T.5
Fischmeister, R.6
-
96
-
-
0025335924
-
4-DAMP analogues reveal heterogeneity of M1 muscarinic receptors
-
Micheletti R, Giudici L, Turconi M and Donetti A (1990a) 4-DAMP analogues reveal heterogeneity of M1 muscarinic receptors. Br J Pharmacol 100:395-397.
-
(1990)
Br J Pharmacol
, vol.100
, pp. 395-397
-
-
Micheletti, R.1
Giudici, L.2
Turconi, M.3
Donetti, A.4
-
97
-
-
0025094447
-
Affinity profile of the novel muscarinic antagonist guanylpirenzepine
-
Micheletti R, Schiavone A, Angelici O, Duranti P, Giudici L, Cereda E and Donetti A (1990b) Affinity profile of the novel muscarinic antagonist guanylpirenzepine. Life Sci 47:55-58.
-
(1990)
Life Sci
, vol.47
, pp. 55-58
-
-
Micheletti, R.1
Schiavone, A.2
Angelici, O.3
Duranti, P.4
Giudici, L.5
Cereda, E.6
Donetti, A.7
-
98
-
-
0023819055
-
Muscarinic M1 receptors stimulate a nonadrenergic noncholinergic inhibitory pathway in the isolated rat duodenum
-
Micheletti R, Schiavone A and Giachetti A (1988) Muscarinic M1 receptors stimulate a nonadrenergic noncholinergic inhibitory pathway in the isolated rat duodenum. J Pharmacol Exp Ther 244:680-684.
-
(1988)
J Pharmacol Exp Ther
, vol.244
, pp. 680-684
-
-
Micheletti, R.1
Schiavone, A.2
Giachetti, A.3
-
99
-
-
0030048466
-
Induction of muscarinic receptor subtypes in monocytic/macrophagic cells differentiated from EoL-1 cells
-
Mita Y, Dobashi K, Susuki K, Mori M and Nakazawa T (1996) Induction of muscarinic receptor subtypes in monocytic/macrophagic cells differentiated from EoL-1 cells. Eur J Pharmacol 297:121-127.
-
(1996)
Eur J Pharmacol
, vol.297
, pp. 121-127
-
-
Mita, Y.1
Dobashi, K.2
Susuki, K.3
Mori, M.4
Nakazawa, T.5
-
100
-
-
0013640165
-
The binding profile of the novel muscarinic receptor antagonist darifenacin against the five cloned human muscarinic receptors expressed in CHO cells
-
Nunn PA, Greengrass PM, Newgreen DT, Naylor AM and Wallis RM (1996) The binding profile of the novel muscarinic receptor antagonist darifenacin against the five cloned human muscarinic receptors expressed in CHO cells (abstract). Br J Pharmacol 117:130P.
-
(1996)
Br J Pharmacol
, vol.117
-
-
Nunn, P.A.1
Greengrass, P.M.2
Newgreen, D.T.3
Naylor, A.M.4
Wallis, R.M.5
-
101
-
-
0029922183
-
Rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity: Potent block by the selective m4 ligand muscarinic toxin 3 (MT3)
-
Olianas MC, Adem A, Karlsson E and Onali P (1996) Rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity: Potent block by the selective m4 ligand muscarinic toxin 3 (MT3). Br J Pharmacol 118:283-288.
-
(1996)
Br J Pharmacol
, vol.118
, pp. 283-288
-
-
Olianas, M.C.1
Adem, A.2
Karlsson, E.3
Onali, P.4
-
102
-
-
0024978524
-
Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor
-
Onai T, FitzGerald MG, Arakawa S, Gocayne JD, Urquhart DA, Hall LM, Fraser CM, McCombie WR and Venter JC (1989) Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor. FEBS Lett 255:219-225.
-
(1989)
FEBS Lett
, vol.255
, pp. 219-225
-
-
Onai, T.1
FitzGerald, M.G.2
Arakawa, S.3
Gocayne, J.D.4
Urquhart, D.A.5
Hall, L.M.6
Fraser, C.M.7
McCombie, W.R.8
Venter, J.C.9
-
103
-
-
0028957379
-
Bimodal regulation of cyclic AMP by muscarinic receptors: Involvement of multiple G proteins and different forms of adenylyl cyclase
-
Onali P and Olianas MC (1995) Bimodal regulation of cyclic AMP by muscarinic receptors: Involvement of multiple G proteins and different forms of adenylyl cyclase. Life Sci 56:973-980.
-
(1995)
Life Sci
, vol.56
, pp. 973-980
-
-
Onali, P.1
Olianas, M.C.2
-
104
-
-
0023191611
-
Subtypes of muscarinic receptors on adrenergic nerves and vascular smooth muscle of the canine saphenous vein
-
O'Rourke ST and Vanhoutte PM (1987) Subtypes of muscarinic receptors on adrenergic nerves and vascular smooth muscle of the canine saphenous vein. J Pharmacol Exp Ther 241:64-67.
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 64-67
-
-
O'Rourke, S.T.1
Vanhoutte, P.M.2
-
105
-
-
0031009124
-
Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic acetylcholine receptor
-
Pals-Rylaarsdam R and Hosey MM (1997) Two homologous phosphorylation domains differentially contribute to desensitization and internalization of the m2 muscarinic acetylcholine receptor. J Biol Chem 272:14152-14158.
-
(1997)
J Biol Chem
, vol.272
, pp. 14152-14158
-
-
Pals-Rylaarsdam, R.1
Hosey, M.M.2
-
106
-
-
0025315790
-
Expression and pharmacological characterization of the human Ml muscarinic receptor in Saccharomyces cerevisiae
-
Payette P, Gossard F, Whiteway M and Dennis M (1990) Expression and pharmacological characterization of the human Ml muscarinic receptor in Saccharomyces cerevisiae. FEBS Lett 266:21-25.
-
(1990)
FEBS Lett
, vol.266
, pp. 21-25
-
-
Payette, P.1
Gossard, F.2
Whiteway, M.3
Dennis, M.4
-
107
-
-
0025891771
-
Modulation of the structure-binding relationships of antagonists for muscarinic acetylcholine receptor subtypes
-
Pedder EK, Eveleigh P, Poyner D, Hulme EC and Birdsall NJM (1991) Modulation of the structure-binding relationships of antagonists for muscarinic acetylcholine receptor subtypes. Br J Pharmacol 103:1561-1567.
-
(1991)
Br J Pharmacol
, vol.103
, pp. 1561-1567
-
-
Pedder, E.K.1
Eveleigh, P.2
Poyner, D.3
Hulme, E.C.4
Birdsall, N.J.M.5
-
108
-
-
0023661365
-
Distinct primary structures, ligand binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors
-
Peralta EG, Ashkenazi A, Winslow JW, Smith DH, Ramachandran J and Capon DJ (1987) Distinct primary structures, ligand binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors. EMBO J 6:3923-3929.
-
(1987)
EMBO J
, vol.6
, pp. 3923-3929
-
-
Peralta, E.G.1
Ashkenazi, A.2
Winslow, J.W.3
Smith, D.H.4
Ramachandran, J.5
Capon, D.J.6
-
109
-
-
0013550718
-
Functional characterization of muscarinic receptors in rat duodenum
-
Pfaff O, Gross J, Waelbroeck M, Mutschler E and Lambrecht G (1995) Functional characterization of muscarinic receptors in rat duodenum (abstract). Life Sci 56:1038.
-
(1995)
Life Sci
, vol.56
, pp. 1038
-
-
Pfaff, O.1
Gross, J.2
Waelbroeck, M.3
Mutschler, E.4
Lambrecht, G.5
-
110
-
-
0028840330
-
Competition between positive and negative allosteric effectors on muscarinic receptors
-
Proska J and Tucek S (1995) Competition between positive and negative allosteric effectors on muscarinic receptors. Mol Pharmacol 48:696-702.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 696-702
-
-
Proska, J.1
Tucek, S.2
-
112
-
-
0028926113
-
Human muscarinic receptors expressed in A9L and CHO cells: Activation by full and partial agonists
-
Richards MH and Van Giersbergen PL (1995) Human muscarinic receptors expressed in A9L and CHO cells: Activation by full and partial agonists. Br J Pharmacol 114:1242-1249.
-
(1995)
Br J Pharmacol
, vol.114
, pp. 1242-1249
-
-
Richards, M.H.1
VanGiersbergen, P.L.2
-
113
-
-
0001004352
-
The pharmacology of flaxedil with observations on certain analogs
-
Riker WF and Wescoe WC (1951) The pharmacology of flaxedil with observations on certain analogs. Ann NY Acad Sci 54:373-394.
-
(1951)
Ann NY Acad Sci
, vol.54
, pp. 373-394
-
-
Riker, W.F.1
Wescoe, W.C.2
-
114
-
-
0030175612
-
Nicotinic receptors in the development and modulation of CNS synapses
-
Role LW and Berg DK (1996) Nicotinic receptors in the development and modulation of CNS synapses. Neuron 16:1077-1085.
-
(1996)
Neuron
, vol.16
, pp. 1077-1085
-
-
Role, L.W.1
Berg, D.K.2
-
115
-
-
0000015314
-
An unusual type of sympathetic ganglionic stimulant
-
Roszkowski AP (1961) An unusual type of sympathetic ganglionic stimulant. J Pharmacol Exp Ther 132:156-170.
-
(1961)
J Pharmacol Exp Ther
, vol.132
, pp. 156-170
-
-
Roszkowski, A.P.1
-
116
-
-
0030894832
-
Muscarinic acetylcholine receptor subtype, m2: Diverse functional implications of differential synaptic localization
-
Rouse ST, Thomas TM and Levey AI (1997) Muscarinic acetylcholine receptor subtype, m2: Diverse functional implications of differential synaptic localization. Life Sci 60:1031-1038.
-
(1997)
Life Sci
, vol.60
, pp. 1031-1038
-
-
Rouse, S.T.1
Thomas, T.M.2
Levey, A.I.3
-
118
-
-
0026639831
-
Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor: Role of conserved cysteines in receptor function
-
Savarese TM, Wang CD and Fraser CM (1992) Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor: Role of conserved cysteines in receptor function. J Biol Chem 267:11439-11448.
-
(1992)
J Biol Chem
, vol.267
, pp. 11439-11448
-
-
Savarese, T.M.1
Wang, C.D.2
Fraser, C.M.3
-
119
-
-
0030984542
-
In vivo pharmacology of butylthio[2,2,2] (LY297802/NNC11-1053), an orally acting antinociceptive muscarinic agonist
-
Shannon HE, Womer DE, Bymaster FP, Calligaro DP, Delapp NC, Mitch NC, Ward JS, Whitesitt CA, Swedberg MDB, Sheardown MJ, Fink-Jensen A, Olesen PB, Rimvall K and Sauerberg P (1997) In vivo pharmacology of butylthio[2,2,2] (LY297802/NNC11-1053), an orally acting antinociceptive muscarinic agonist. Life Sci 60:969-976.
-
(1997)
Life Sci
, vol.60
, pp. 969-976
-
-
Shannon, H.E.1
Womer, D.E.2
Bymaster, F.P.3
Calligaro, D.P.4
Delapp, N.C.5
Mitch, N.C.6
Ward, J.S.7
Whitesitt, C.A.8
Swedberg, M.D.B.9
Sheardown, M.J.10
Fink-Jensen, A.11
Olesen, P.B.12
Rimvall, K.13
Sauerberg, P.14
-
120
-
-
0024391090
-
Characterization and functional expression in mammalian cells of genomic and cDNA clones encoding a Drosophila muscarinic acetylcholine receptor
-
Shapiro RA, Wakimoto BT, Subers EM and Nathanson NM (1989) Characterization and functional expression in mammalian cells of genomic and cDNA clones encoding a Drosophila muscarinic acetylcholine receptor. Proc Natl Acad Sci USA 86:9039-9043.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 9039-9043
-
-
Shapiro, R.A.1
Wakimoto, B.T.2
Subers, E.M.3
Nathanson, N.M.4
-
121
-
-
0030951466
-
Does mammalian heart contain only the M2 muscarinic receptor subtype?
-
Sharma VK, Colecraft HM, Rubin LE and Sheu S-S (1997) Does mammalian heart contain only the M2 muscarinic receptor subtype? Life Sci 60:1023-1029.
-
(1997)
Life Sci
, vol.60
, pp. 1023-1029
-
-
Sharma, V.K.1
Colecraft, H.M.2
Rubin, L.E.3
Sheu, S.-S.4
-
122
-
-
0021246750
-
Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells
-
Soejima M and Noma A(1984) Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells. Pflugers Arch 400:424-431.
-
(1984)
Pflugers Arch
, vol.400
, pp. 424-431
-
-
Soejima, M.1
Noma, A.2
-
123
-
-
0028087860
-
Acetylcholine mustard labels the binding site aspartate in muscarinic acetylcholine receptors
-
Spalding TA, Birdsall NJM, Curtis CAM and Hulme EC (1994) Acetylcholine mustard labels the binding site aspartate in muscarinic acetylcholine receptors. J Biol Chem 269:4092-4097.
-
(1994)
J Biol Chem
, vol.269
, pp. 4092-4097
-
-
Spalding, T.A.1
Birdsall, N.J.M.2
Curtis, C.A.M.3
Hulme, E.C.4
-
124
-
-
0020533362
-
Modification of the binding properties of muscarinic receptors by gallamine
-
Stockton JM, Birdsall NJM, Burgen AS and Hulme EC (1983) Modification of the binding properties of muscarinic receptors by gallamine. Mol Pharmacol 23:551-557.
-
(1983)
Mol Pharmacol
, vol.23
, pp. 551-557
-
-
Stockton, J.M.1
Birdsall, N.J.M.2
Burgen, A.S.3
Hulme, E.C.4
-
126
-
-
0026014153
-
Embryonic chick heart expresses multiple muscarinic acetylcholine receptor subtypes: Isolation and characterization of a gene encoding a novel m2 muscarinic acetylcholine receptor with a high affinity for pirenzepine
-
Tietje KM and Nathanson NM (1991) Embryonic chick heart expresses multiple muscarinic acetylcholine receptor subtypes: Isolation and characterization of a gene encoding a novel m2 muscarinic acetylcholine receptor with a high affinity for pirenzepine. J Biol Chem 266:17382-17387.
-
(1991)
J Biol Chem
, vol.266
, pp. 17382-17387
-
-
Tietje, K.M.1
Nathanson, N.M.2
-
127
-
-
0025203309
-
Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors
-
Tucek S, Musilkova J, Nedoma J, Proska J, Shelkovnikov S and Vorlicek J (1990) Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors. Mol Pharmacol 38:674-680.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 674-680
-
-
Tucek, S.1
Musilkova, J.2
Nedoma, J.3
Proska, J.4
Shelkovnikov, S.5
Vorlicek, J.6
-
129
-
-
0025642826
-
Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor: Analysis of the role of N-glycosylation in receptor expression and function
-
Van Koppen CJ and Nathanson NM (1990) Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor: Analysis of the role of N-glycosylation in receptor expression and function. J Biol Chem 265:20887-20892.
-
(1990)
J Biol Chem
, vol.265
, pp. 20887-20892
-
-
VanKoppen, C.J.1
Nathanson, N.M.2
-
130
-
-
0028914060
-
Muscarinic receptors and drugs in cardiovascular medicine
-
Van Zwieten PA and Doods HN (1995) Muscarinic receptors and drugs in cardiovascular medicine. Cardiovasc Drugs Ther 9:159-167.
-
(1995)
Cardiovasc Drugs Ther
, vol.9
, pp. 159-167
-
-
VanZwieten, P.A.1
Doods, H.N.2
-
131
-
-
0028876894
-
Characterization of the rat m3 muscarinic acetylcholine receptor produced in insect cells infected with recombinant baculovirus
-
Vasudevan S, Hulme EC, Bach M, Haase W, Pavia J and Reilander H (1995) Characterization of the rat m3 muscarinic acetylcholine receptor produced in insect cells infected with recombinant baculovirus. Eur J Biochem 227:466-475.
-
(1995)
Eur J Biochem
, vol.227
, pp. 466-475
-
-
Vasudevan, S.1
Hulme, E.C.2
Bach, M.3
Haase, W.4
Pavia, J.5
Reilander, H.6
-
132
-
-
0028006501
-
Multiplicity of muscarinic autoreceptor subtypes? Comparison of the distribution of cholinergic cells and cells containing mRNA for five subtypes of muscarinic receptors in the brain
-
Vilaro MT, Palacios JM and Mengod G (1994) Multiplicity of muscarinic autoreceptor subtypes? Comparison of the distribution of cholinergic cells and cells containing mRNA for five subtypes of muscarinic receptors in the brain. Mol Brain Res 21:30-46.
-
(1994)
Mol Brain Res
, vol.21
, pp. 30-46
-
-
Vilaro, M.T.1
Palacios, J.M.2
Mengod, G.3
-
133
-
-
0029012939
-
Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells
-
Vogel WK, Mosser VA, Bulseco DA and Schimerlik MI (1995) Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells. J Biol Chem 270:15485-15493.
-
(1995)
J Biol Chem
, vol.270
, pp. 15485-15493
-
-
Vogel, W.K.1
Mosser, V.A.2
Bulseco, D.A.3
Schimerlik, M.I.4
-
134
-
-
0028866902
-
Expression of CSA-hm2 fusion in Dictyostelium discoideum under the control of the Dictyostelium ras promoter reveals functional muscarinic receptors
-
Voith G and Dingermann T (1995) Expression of CSA-hm2 fusion in Dictyostelium discoideum under the control of the Dictyostelium ras promoter reveals functional muscarinic receptors. Pharmazie 50:758-762.
-
(1995)
Pharmazie
, vol.50
, pp. 758-762
-
-
Voith, G.1
Dingermann, T.2
-
135
-
-
0028175929
-
Binding and functional properties of hexocyclium and sila-hexocyclium derivatives to muscarinic receptor subtypes
-
Waelbroeck M, Camus J, Tastenoy M, Feifel R, Mutschler E, Tacke R, Strohmann C, Rafeiner K, Rodrigues de Miranda JF and Lambrecht G (1994) Binding and functional properties of hexocyclium and sila-hexocyclium derivatives to muscarinic receptor subtypes. Br J Pharmacol 112:505-514.
-
(1994)
Br J Pharmacol
, vol.112
, pp. 505-514
-
-
Waelbroeck, M.1
Camus, J.2
Tastenoy, M.3
Feifel, R.4
Mutschler, E.5
Tacke, R.6
Strohmann, C.7
Rafeiner, K.8
De Rodrigues Miranda, J.F.9
Lambrecht, G.10
-
136
-
-
0024989541
-
Binding of antagonists to four muscarinic receptors (M1-M4) in rat forebrain
-
Waelbroeck M, Tastenoy M, Camus J and Christrophe J (1990) Binding of antagonists to four muscarinic receptors (M1-M4) in rat forebrain. Mol Pharmacol 38:267-273.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 267-273
-
-
Waelbroeck, M.1
Tastenoy, M.2
Camus, J.3
Christrophe, J.4
-
137
-
-
0025793911
-
Production of antisera selective for m1 muscarinic receptors using fusion proteins: Distribution of m1 receptors in the brain
-
Wall S, Yasuda RP, Hory F, Flagg S, Martin BM, Ginns EL and Wolfe BB (1991a) Production of antisera selective for m1 muscarinic receptors using fusion proteins: Distribution of m1 receptors in the brain. Mol Pharmacol 39:643-649.
-
(1991)
Mol Pharmacol
, vol.39
, pp. 643-649
-
-
Wall, S.1
Yasuda, R.P.2
Hory, F.3
Flagg, S.4
Martin, B.M.5
Ginns, E.L.6
Wolfe, B.B.7
-
138
-
-
0025751636
-
Development of an antiserum against m3 muscarinic receptors: Distribution of m3 receptor in rat tissues and clonal cell lines
-
Wall S, Yasuda RP, Li M and Wolfe BB (1991b) Development of an antiserum against m3 muscarinic receptors: Distribution of m3 receptor in rat tissues and clonal cell lines. Mol Pharmacol 40:783-789.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 783-789
-
-
Wall, S.1
Yasuda, R.P.2
Li, M.3
Wolfe, B.B.4
-
139
-
-
0013610266
-
Comparative pharmacology of human muscarinic m3 and m5 cholinoreceptors expressed in Chinese hamster ovary cells
-
Watson N, Daniels DV, Ford APDW, Eglen RM and Hegde SS (1998) Comparative pharmacology of human muscarinic m3 and m5 cholinoreceptors expressed in Chinese hamster ovary cells (abstract). Br J Pharmacol, 123:268P.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 268
-
-
Watson, N.1
Daniels, D.V.2
Ford, A.P.D.W.3
Eglen, R.M.4
Hegde, S.S.5
-
140
-
-
0029552607
-
Pharmacological characterization of the muscarinic receptors mediating contraction of canine saphenous vein
-
Watson N, Reddy H and Eglen RM (1995) Pharmacological characterization of the muscarinic receptors mediating contraction of canine saphenous vein. J Auton Pharmacol 15:437-441.
-
(1995)
J Auton Pharmacol
, vol.15
, pp. 437-441
-
-
Watson, N.1
Reddy, H.2
Eglen, R.M.3
-
141
-
-
0025130727
-
Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia
-
Weiner DM, Levey AI and Brann MR (1990) Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia. Proc Natl Acad Sci USA 87:7050-7054.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7050-7054
-
-
Weiner, D.M.1
Levey, A.I.2
Brann, M.R.3
-
142
-
-
0027328091
-
Molecular basis of muscarinic acetylcholine receptor function
-
Wess J (1993) Molecular basis of muscarinic acetylcholine receptor function. Trends Pharmacol Sci 14:308-313.
-
(1993)
Trends Pharmacol Sci
, vol.14
, pp. 308-313
-
-
Wess, J.1
-
143
-
-
0029789994
-
Molecular biology of muscarinic acetylcholine receptors
-
Wess J (1996) Molecular biology of muscarinic acetylcholine receptors. Crit Rev Neurobiol 10:69-99.
-
(1996)
Crit Rev Neurobiol
, vol.10
, pp. 69-99
-
-
Wess, J.1
-
144
-
-
0025153423
-
Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers
-
Wess J, Bonner TI, Dörje F and Brann MR (1990) Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers. Mol Pharmacol 38:517-523.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 517-523
-
-
Wess, J.1
Bonner, T.I.2
Dörje, F.3
Brann, M.R.4
-
145
-
-
0026517079
-
Structural basis of the subtype selectivity of muscarinic antagonists: A study with chimeric m2/m5 muscarinic receptors
-
Wess J, Gdula D and Brann MR (1992) Structural basis of the subtype selectivity of muscarinic antagonists: A study with chimeric m2/m5 muscarinic receptors. Mol Pharmacol 41:369-374.
-
(1992)
Mol Pharmacol
, vol.41
, pp. 369-374
-
-
Wess, J.1
Gdula, D.2
Brann, M.R.3
-
146
-
-
0030935667
-
Structural basis of receptor/G protein coupling selectivity studied with muscarinic receptors as model systems
-
Wess J, Liu J, Blin N, Yun J, Lerche C and Kostenis E (1997) Structural basis of receptor/G protein coupling selectivity studied with muscarinic receptors as model systems. Life Sci 60:1007-1014.
-
(1997)
Life Sci
, vol.60
, pp. 1007-1014
-
-
Wess, J.1
Liu, J.2
Blin, N.3
Yun, J.4
Lerche, C.5
Kostenis, E.6
-
147
-
-
0007667725
-
Mutational analysis of muscarinic receptors: Structural basis of ligand binding and G protein recognition
-
Wess J ed R. G. Landes, Austin
-
Wess J, Liu J, Blüml K, Yun J, Schoneberg T and Blin N (1995) Mutational analysis of muscarinic receptors: Structural basis of ligand binding and G protein recognition, in Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function (Wess J ed) pp 1-18, R. G. Landes, Austin.
-
(1995)
Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function
, pp. 1-18
-
-
Wess, J.1
Liu, J.2
Blüml, K.3
Yun, J.4
Schoneberg, T.5
Blin, N.6
-
148
-
-
0028820687
-
Ion channel regulation by G proteins
-
Wickman K and Clapham DE (1995) Ion channel regulation by G proteins. Physiol Rev 75:865-885.
-
(1995)
Physiol Rev
, vol.75
, pp. 865-885
-
-
Wickman, K.1
Clapham, D.E.2
-
149
-
-
0027497533
-
Development of antisera for m4 and m5 muscarinic cholinergic receptors: Distribution of m4 and m5 receptors in rat brain
-
Yasuda RP, Ciesla W, Flores LR, Wall SJ, Li M, Satkus SA, Weisstein JS, Spagnola BV and Wolfe BB (1993) Development of antisera for m4 and m5 muscarinic cholinergic receptors: Distribution of m4 and m5 receptors in rat brain. Mol Pharmacol 43:149-157.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 149-157
-
-
Yasuda, R.P.1
Ciesla, W.2
Flores, L.R.3
Wall, S.J.4
Li, M.5
Satkus, S.A.6
Weisstein, J.S.7
Spagnola, B.V.8
Wolfe, B.B.9
-
150
-
-
0009603660
-
An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor
-
Zhu SZ, Wang SZ, Hu J and El-Fakahany EE (1994) An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor. Mol Pharmacol 45:517-523.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 517-523
-
-
Zhu, S.Z.1
Wang, S.Z.2
Hu, J.3
El-Fakahany, E.E.4
|