Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex

Journal of Pharmacology and Experimental Therapeutics

Volumn 294, Issue 3, 2000, Pages 1017-1023

  Jones, C K ^a   Shannon, H E ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYL 8 METHYL 2,8 DIAZASPIRO[4.5]DECANE 1,3 DIONE; ARECOLINE; BENZATROPINE; BIPERIDEN; CHOLINESTERASE INHIBITOR; DICYCLOVERINE; MECAMYLAMINE; MUSCARINIC AGENT; MUSCARINIC RECEPTOR BLOCKING AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; OXOTREMORINE; PHYSOSTIGMINE; PILOCARPINE; SCOPOLAMINE; SCOPOLAMINE DERIVATIVE; TACRINE; TRIHEXYPHENIDYL;

ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; MALE; NEUROMODULATION; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; STARTLE REFLEX;

ACOUSTIC STIMULATION; ANIMALS; CHOLINESTERASE INHIBITORS; MALE; MECAMYLAMINE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; NICOTINIC ANTAGONISTS; OXOTREMORINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; REFLEX; SCOPOLAMINE; STARTLE REACTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033838430     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. The effects of physostigmine and scopolamine on recognition memory in monkeys
2. Scopolamine impairs recall of one-trial stimulus-reward association in monkeys
3. Short-term memory in the rhesus monkey: Disruption from the anticholinergic scopolamine
4. Tetrahydroaminoacridine, 3,4 diaminopyridine and physostigmine: Direct comparison of effects on memory in aged primates
5. Scopolamine impairs encoding and retrieval of spatial working memory in rats
6. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer's disease
7. Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells
8. Gating and habituation of the startle reflex in schizophrenic patients
9. Antagonist binding properties of five cloned muscarinic receptor expressed in CHO-K1 cells
10. Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
11. Continuous ICV infusion of scopolamine impairs sustained attention of rhesus monkeys
12. Alzheimer's disease: A disorder of cortical cholinergic innervation
13. Effects of nicotine, lobeline, and mecamylamine on sensory gating in the rat
14. Memory and cognitive function in man: Does the cholinergic system have a specific role?
15. Catecholamine uptake by synaptosomes from rat brain: Structure-activity relationships of drugs with differential effects on dopamine and norepinephrine neurons
16. Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists
17. Bilateral lesions of the laterodorsal tegmental nucleus disrupt prepulse inhibition of acoustic startle reflex in rats
18. Effects of scopolamine in comparison with apomorphine and phencyclidine on prepulse inhibition in rats
19. Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse inhibition of the acoustic startle response in the rat
20. Loss of M2 muscarinic receptors in the central cortex in Alzheimer's disease and experimental cholinergic denervation
21. Dopaminergic activity of the 'antimus-carinic' antiparkinsonian agents
22. Oral physostigmine treatment of patients with Alzheimer's disease
23. Scopolamine induced learning failures in man
24. Comparison of the effects of four cholinomimetic agents on cognition in primates following disruption by scopolamine or by lists of objects
25. The effects of scopolamine on working memory in healthy young volunteers
26. Assessment of working memory in rats using spatial alteration behavior with variable retention intervals: Effects of fixed-ratio size and scopolamine
27. Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhihitors on spatial alternation performance in rats
28. Regionally selective effects of intra-cerebral dopamine infusion on sensorimeter gating of the startle reflex in rats
29. Prepulse inhibition of acoustic startle in rats after lesions of the pedunculopontine tegmental nucleus
30. Using an animal model of deficit sensorimotor gating to study the pathophysiology and new treatment of schizophrenia
31. Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats
32. Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain
33. Schizophrenia and Alzheimer's disease: Clinical and pathophysiologic analogies
34. Cholinergic mechanisms in startle and prepulse inhibition: Effects of the false cholinergic precursor N-aminodeanol