Dissociable effects of histamine H1 antagonists on reaction-time performance in rats

Pharmacology Biochemistry and Behavior

Volumn 70, Issue 2-3, 2001, Pages 427-436

  Blokland, Arjan ^b   Scholtissen, Bart ^a   Vermeeren, Annemiek ^a   Ramaekers, Jan ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b NONE

Author keywords

Histamine; Psychomotor function; Reaction time; Scopolamine; Sedation; Side effect

Indexed keywords

CETIRIZINE; DIPHENHYDRAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; SCOPOLAMINE; TERFENADINE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DISSOCIATION; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; MALE; MOTOR PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; PSYCHOMOTOR ACTIVITY; RAT; REACTION TIME; RECEPTOR BLOCKING; TASK PERFORMANCE;

ANIMALS; CETIRIZINE; DIPHENHYDRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE H1 ANTAGONISTS; MALE; PSYCHOMOTOR PERFORMANCE; RATS; RATS, INBRED LEW; REACTION TIME; TERFENADINE;

EID: 0035167075     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00627-X     Document Type: Article

References (24)

1. Depletion of dopamine in the caudate nucleus but not in nucleus accumbens impairs reaction-time performance in rats
2. Complex deficits on reaction time performance following bilateral intrastriatal 6-OHDA infusion in the rat
3. In a rat model of parkinsonism, lesions of the subthalamic nucleus reverse increases of reaction time but induce a dramatic premature responding deficit
4. Reaction time responding in rats
5. Intra-striatal haloperidol and scopolamine injections: Effects on choice reaction time performance in rats
6. Differentiating the effects of centrally acting drugs on arousal and memory: An event-related potential study of scopolamine, lorazepam and diphenhydramine
7. Unilateral striatal lesions impair response execution on a lateralised choice reaction time task
8. Activation of mesolimbic dopaminergic neurons following central administration of histamine is mediated by H1 receptors
9. Antihistamines: Models to assess sedative properties, assessment of sedation, safety and other side-effects
10. Age-related decline of psychomotor speed: Effects of age, brain health, sex, and education
11. The effects of antihistamines on cognition and performance
12. Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assay
13. Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat
14. Sedation with "non-sedating" antihistamines: Four prescription-event monitoring studies in general practice
15. Stimulant actions of histamine H1 antagonists on operant behavior in the squirrel monkey
16. Differential-reinforcement-of-low-rate 72-second schedule: Selective effects of antidepressant drugs
17. Central histaminergic system and cognition
18. All antihistamines cross blood-brain barrier
19. Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving
20. Psychometric aspects of antihistamines: A review
21. Metabolism and functions of histamine in the brain
22. H1-receptor antagonists. Comparative tolerability and safety
23. Differential effects of dopamine receptor subtype blockade on performance of rats in a reaction-time paradigm
24. Behavioural effects of histamine and its antagonists: A review