메뉴 건너뛰기




Volumn 7, Issue 7, 2010, Pages 795-809

Cationic nanoparticles for cancer therapy

Author keywords

Cationic polymer; Chitosan; Complement activation; Cyclodextrin polymers; Cytotoxicity; Dendrimers; Nanoparticles; Pharmacokinetics; Poly L lysine; Polyethylene imine; Polymethacrylates

Indexed keywords

CATION; CATIONIC NANOPARTICLE; CHITOSAN; CISPLATIN; DENDRIMER; IMIDAZOLE DERIVATIVE; NANOPARTICLE; PLASMID DNA; POLYETHYLENEIMINE; POLYLYSINE; POLYMETHACRYLIC ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

EID: 77953856405     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.2010.485983     Document Type: Review
Times cited : (112)

References (143)
  • 2
    • 42249095834 scopus 로고    scopus 로고
    • Multi-functional nanoparticles and their role in cancer drug delivery- a review
    • Pathak P, Kathiyar VK. Multi-functional nanoparticles and their role in cancer drug delivery- a review. J Nanotechnol Online 2007;3:1-17
    • (2007) J Nanotechnol Online , vol.3 , pp. 1-17
    • Pathak, P.1    Kathiyar, V.K.2
  • 4
    • 66149110011 scopus 로고    scopus 로고
    • Nano particles and cancer theraphy: A concise review with emphasis on dendrimers
    • Bharali DJ, Khalil M, Gurbuz M, et al. Nano particles and cancer theraphy: a concise review with emphasis on dendrimers. Int J Nanomed 2009;4:1-7
    • (2009) Int J Nanomed , vol.4 , pp. 1-7
    • Bharali, D.J.1    Khalil, M.2    Gurbuz, M.3
  • 5
    • 0024505574 scopus 로고
    • Delivery of novel therapeutic agents in tumors-physiological barriers and strategies
    • Jain RK. Delivery of novel therapeutic agents in tumors-physiological barriers and strategies. J Natl Cancer Inst 1989;81:570-576
    • (1989) J Natl Cancer Inst , vol.81 , pp. 570-576
    • Jain, R.K.1
  • 6
    • 0035291243 scopus 로고    scopus 로고
    • Delivery of molecular and cellular medicine to solid tumors
    • Jain RK. Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev 2001;46:149-168
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 149-168
    • Jain, R.K.1
  • 7
    • 24144490542 scopus 로고    scopus 로고
    • Targeting cancer cells with DNA-Assembled Dendrimers a mix and match strategy for cancer
    • Baker JR Jr, Choi Y. Targeting cancer cells with DNA-Assembled Dendrimers a mix and match strategy for cancer. Cell Cycle 2005;4:669-671
    • (2005) Cell Cycle , vol.4 , pp. 669-671
    • Baker Jr., J.R.1    Choi, Y.2
  • 8
    • 34250165021 scopus 로고    scopus 로고
    • Nanotechnology platforms and physiological challenges for cancer therapeutics
    • Kim KY. Nanotechnology platforms and physiological challenges for cancer therapeutics. Nanomed Nanotechnol Biol Med 2007;3:103-110
    • (2007) Nanomed Nanotechnol Biol Med , vol.3 , pp. 103-110
    • Kim, K.Y.1
  • 9
    • 60749099362 scopus 로고    scopus 로고
    • Dendrimers as versatile platform in drug delivery applications
    • Svenson S. Dendrimers as versatile platform in drug delivery applications. Eur J Pharm Biopharm 2009;71:445-462
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 445-462
    • Svenson, S.1
  • 10
    • 0034019945 scopus 로고    scopus 로고
    • Cationic polymer based gene delivery systems
    • DeSmedt SC, Demeester J, Hennink WE. Cationic polymer based gene delivery systems. Pharm Res 2000;17(2):113-126
    • (2000) Pharm Res , vol.17 , Issue.2 , pp. 113-126
    • De Smedt, S.C.1    Demeester, J.2    Hennink, W.E.3
  • 11
    • 14044272234 scopus 로고    scopus 로고
    • Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters)
    • Anderson DG, Akinc A, Hossain N, Langer R. Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Mol Ther 2005;11(3):426-434
    • (2005) Mol Ther , vol.11 , Issue.3 , pp. 426-434
    • Anderson, D.G.1    Akinc, A.2    Hossain, N.3    Langer, R.4
  • 12
    • 8644275490 scopus 로고    scopus 로고
    • A polymer library approach to suicide gene therapy for cancer
    • Anderson DG, Peng W, Akinc A, et al. A polymer library approach to suicide gene therapy for cancer. Proc Natl Acad Sci USA 2004;101(45):16028-16033
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.45 , pp. 16028-16033
    • Anderson, D.G.1    Peng, W.2    Akinc, A.3
  • 13
    • 33749012572 scopus 로고    scopus 로고
    • Biodegradable polymeric vectors for gene delivery to human endothelial cells
    • Green JJ, Shi J, Chiu E, et al. Biodegradable polymeric vectors for gene delivery to human endothelial cells. Bioconjug Chem 2006;17(5):1162-1169
    • (2006) Bioconjug Chem , vol.17 , Issue.5 , pp. 1162-1169
    • Green, J.J.1    Shi, J.2    Chiu, E.3
  • 14
    • 25444482607 scopus 로고    scopus 로고
    • Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
    • Hu-Lieskovan S, Heidel JD, Bartlett DW, et al. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res 2005;65(19):8984-8992
    • (2005) Cancer Res , vol.65 , Issue.19 , pp. 8984-8992
    • Hu-Lieskovan, S.1    Heidel, J.D.2    Bartlett, D.W.3
  • 15
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J, et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res 2004;32(19):e149
    • (2004) Nucleic Acids Res , vol.32 , Issue.19
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3
  • 16
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethyleneimine (PEI)-complexed siRNA in vivo
    • Urban-Klein B, Werth S, Abuharbeid S, et al. RNAi-mediated gene-targeting through systemic application of polyethyleneimine (PEI)-complexed siRNA in vivo. Gene Ther 2005;12(5):461-466
    • (2005) Gene Ther , vol.12 , Issue.5 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3
  • 17
    • 33749983751 scopus 로고    scopus 로고
    • Co-delivery of drugs and DNA from cationic core-shell nanoparticles self assembled from a biodegradable copolymer
    • Wang Y, Gao S, Ye WH, et al. Co-delivery of drugs and DNA from cationic core-shell nanoparticles self assembled from a biodegradable copolymer. Nat Mater 2006;5(10):791-796
    • (2006) Nat Mater , vol.5 , Issue.10 , pp. 791-796
    • Wang, Y.1    Gao, S.2    Ye, W.H.3
  • 18
    • 37249093948 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticle delivery systems for cancer therapy
    • Pridgen EM, Langer R, Farokhzad OC. Biodegradable polymeric nanoparticle delivery systems for cancer therapy. Nanomedicine 2007;2(5):669-680
    • (2007) Nanomedicine , vol.2 , Issue.5 , pp. 669-680
    • Pridgen, E.M.1    Langer, R.2    Farokhzad, O.C.3
  • 19
    • 8544230612 scopus 로고    scopus 로고
    • Cationic compounds used in lipoplexes and polyplexes for gene delivery
    • Zhang S, Xu Y, Wang B, et al. Cationic compounds used in lipoplexes and polyplexes for gene delivery. J Control Release 2004;100:165-180
    • (2004) J Control Release , vol.100 , pp. 165-180
    • Zhang, S.1    Xu, Y.2    Wang, B.3
  • 20
    • 69749099777 scopus 로고    scopus 로고
    • Nanoparticulate systems for polynucleotide delivery
    • Basarkar A, Singh J. Nanoparticulate systems for polynucleotide delivery. Int J Nanomed 2007;2(3):353-360
    • (2007) Int J Nanomed , vol.2 , Issue.3 , pp. 353-360
    • Basarkar, A.1    Singh, J.2
  • 21
    • 14044250982 scopus 로고    scopus 로고
    • Formation and intracellular trafficking of lipoplexes and polyplexes
    • Elouahabi A, Ruysschaert JM. Formation and intracellular trafficking of lipoplexes and polyplexes. Mol Ther 2005;11:336-347
    • (2005) Mol Ther , vol.11 , pp. 336-347
    • Elouahabi, A.1    Ruysschaert, J.M.2
  • 22
    • 0344389048 scopus 로고    scopus 로고
    • Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: Physicochemical and transfection studies
    • Ruponen M, Yla-Herttuala S, Urtti A. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. Biochim Biophys Acta 1999;1415:331-341
    • (1999) Biochim Biophys Acta , vol.1415 , pp. 331-341
    • Ruponen, M.1    Yla-Herttuala, S.2    Urtti, A.3
  • 23
    • 0027179724 scopus 로고
    • Mode of formation and structural features of DNA-cationic liposome complexes used for transfection
    • Gershon H, Ghirlando R, Guttman SB, Minsky A. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 1993;32:7143-7151
    • (1993) Biochemistry , vol.32 , pp. 7143-7151
    • Gershon, H.1    Ghirlando, R.2    Guttman, S.B.3    Minsky, A.4
  • 24
    • 0034971315 scopus 로고    scopus 로고
    • Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives
    • Gao H, Hui KM. Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives. Gene Ther 2001;8:855-863
    • (2001) Gene Ther , vol.8 , pp. 855-863
    • Gao, H.1    Hui, K.M.2
  • 25
    • 33746438424 scopus 로고    scopus 로고
    • Toxicity of cationic lipids and cationic polymers in gene delivery
    • Lv H, Zhang S, Wang B, et al. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 2006;114:100-109
    • (2006) J Control Release , vol.114 , pp. 100-109
    • Lv, H.1    Zhang, S.2    Wang, B.3
  • 26
    • 0347365764 scopus 로고    scopus 로고
    • An overview of current delivery systems in cancer gene therapy
    • El-Aneed A. An overview of current delivery systems in cancer gene therapy. J Control Release 2004;94:1-14
    • (2004) J Control Release , vol.94 , pp. 1-14
    • El-Aneed, A.1
  • 28
  • 29
    • 0035015074 scopus 로고    scopus 로고
    • Chitosan induces apoptosis via caspase-3 activation in bladder tumor cells
    • Hasegawa M, Yagi K, Iwakawa S, Hirai M. Chitosan induces apoptosis via caspase-3 activation in bladder tumor cells. Jpn J Cancer Res 2001;92:459-466
    • (2001) Jpn J Cancer Res , vol.92 , pp. 459-466
    • Hasegawa, M.1    Yagi, K.2    Iwakawa, S.3    Hirai, M.4
  • 30
    • 0031148582 scopus 로고    scopus 로고
    • Laserphotosensitizer assisted immunotherapy: A novel modality for cancer treatment
    • Chen WR, Adams RL, Carubelli R, Nordquist RE. Laserphotosensitizer assisted immunotherapy: a novel modality for cancer treatment. Cancer Lett 1997;115:25-30
    • (1997) Cancer Lett , vol.115 , pp. 25-30
    • Chen, W.R.1    Adams, R.L.2    Carubelli, R.3    Nordquist, R.E.4
  • 31
    • 0021679779 scopus 로고
    • Immunological activity of chitin and its derivatives
    • Nishimura K, Nishimura S, Nishi N, et al. Immunological activity of chitin and its derivatives. Vaccine 1984;2:93-99
    • (1984) Vaccine , vol.2 , pp. 93-99
    • Nishimura, K.1    Nishimura, S.2    Nishi, N.3
  • 32
    • 0024852560 scopus 로고
    • Inhibitory effect of chitin heparinoids on the lung metastasis of B16-BL6 melanoma
    • Murata J, Saiki I, Nishimura S. Inhibitory effect of chitin heparinoids on the lung metastasis of B16-BL6 melanoma. Jpn J Cancer Res 1989;80:866-872
    • (1989) Jpn J Cancer Res , vol.80 , pp. 866-872
    • Murata, J.1    Saiki, I.2    Nishimura, S.3
  • 33
    • 33846021271 scopus 로고    scopus 로고
    • In vitro and in vivo suppression of hepatocellular carcinoma growth by chitosan nanoparticles
    • Qi L, Xu Z, Chen M. In vitro and in vivo suppression of hepatocellular carcinoma growth by chitosan nanoparticles. Eur J Cancer 2007;43:184-193
    • (2007) Eur J Cancer , vol.43 , pp. 184-193
    • Qi, L.1    Xu, Z.2    Chen, M.3
  • 34
    • 34047097273 scopus 로고    scopus 로고
    • Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis
    • Lin SY, Chan HY, Shen FH, et al. Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis. J Cell Biochem 2007;100:1573-1580
    • (2007) J Cell Biochem , vol.100 , pp. 1573-1580
    • Lin, S.Y.1    Chan, H.Y.2    Shen, F.H.3
  • 35
    • 46649092718 scopus 로고    scopus 로고
    • The use of chitosan formulations in cancer therapy
    • Dass CR, Choong PFM. The use of chitosan formulations in cancer therapy. J Microencapsul 2008;25(4):275-279
    • (2008) J Microencapsul , vol.25 , Issue.4 , pp. 275-279
    • Dass, C.R.1    Pfm, C.2
  • 36
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Illum L. Chitosan and its use as a pharmaceutical excipient. Pharm Res 1998;15:1326-1331
    • (1998) Pharm Res , vol.15 , pp. 1326-1331
    • Illum, L.1
  • 37
    • 0037413407 scopus 로고    scopus 로고
    • Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles
    • Xu Y, Du Y. Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. Int J Pharm 2003;250:215-226
    • (2003) Int J Pharm , vol.250 , pp. 215-226
    • Xu, Y.1    Du, Y.2
  • 38
    • 39449102666 scopus 로고    scopus 로고
    • Polymeric nanoparticles for cancer therapy
    • Parveen S, Sahoo SK. Polymeric nanoparticles for cancer therapy. J Drug Target 2008;16(2):108-123
    • (2008) J Drug Target , vol.16 , Issue.2 , pp. 108-123
    • Parveen, S.1    Sahoo, S.K.2
  • 39
    • 1842434428 scopus 로고    scopus 로고
    • Chitosan nanoparticles for plasmid DNA delivery: Effect of chitosan molecular structure on formulation and release characteristics
    • Bozkir A, Saka OM. Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics. Drug Deliv 2004;11:107-112
    • (2004) Drug Deliv , vol.11 , pp. 107-112
    • Bozkir, A.1    Saka, O.M.2
  • 40
    • 0034786764 scopus 로고    scopus 로고
    • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethyleneimine in vitro and after lung administration in vivo
    • Koping-Hoggard M, Tubulekas I, Guan H, et al. Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethyleneimine in vitro and after lung administration in vivo. Gene Ther 2001;8:1108-1121
    • (2001) Gene Ther , vol.8 , pp. 1108-1121
    • Koping-Hoggard, M.1    Tubulekas, I.2    Guan, H.3
  • 41
    • 5444267326 scopus 로고    scopus 로고
    • Improved chitosan mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers
    • Koping-Hoggard M, Varum KM, Issa M, et al. Improved chitosan mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers. Gene Ther 2004;11:1441-1452
    • (2004) Gene Ther , vol.11 , pp. 1441-1452
    • Koping-Hoggard, M.1    Varum, K.M.2    Issa, M.3
  • 42
    • 85047685252 scopus 로고    scopus 로고
    • Cancer, chitosan nanoparticles and catalytic nucleic acids
    • Tan ML, Choong PFM, Dass CR. Cancer, chitosan nanoparticles and catalytic nucleic acids. J Pharm Pharmacol 2009;61:3-12
    • (2009) J Pharm Pharmacol , vol.61 , pp. 3-12
    • Tan, M.L.1    Pfm, C.2    Dass, C.R.3
  • 43
    • 42049121123 scopus 로고    scopus 로고
    • Hydrophobically-modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy
    • Min KH, Park K, Kim YS, et al. Hydrophobically-modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy. J Control Release 2008;127:208-218
    • (2008) J Control Release , vol.127 , pp. 208-218
    • Min, K.H.1    Park, K.2    Kim, Y.S.3
  • 44
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualc'h F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine, Proc Natl Acad Sci 1995; 92:7297-7301
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'H, F.2    Zanta, M.A.3
  • 45
    • 0032811354 scopus 로고    scopus 로고
    • Poly (ethylenimine) and its role in gene delivery
    • Godbey WT, Wu KK, Mikos AG. Poly (ethylenimine) and its role in gene delivery. J Control Release 1999;60:149-160
    • (1999) J Control Release , vol.60 , pp. 149-160
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 46
    • 0037437033 scopus 로고    scopus 로고
    • Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
    • Kunath K, von Harpe A, Fischer D. Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J Control Release 2003;89:113-125
    • (2003) J Control Release , vol.89 , pp. 113-125
    • Kunath, K.1    Von Harpe, A.2    Fischer, D.3
  • 48
    • 17644401347 scopus 로고    scopus 로고
    • Cross-linked small polyethylenimines: While still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo
    • Thomas M, Ge Q, Lu JJ, et al. Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo. Pharm Res 2005;22:373-380
    • (2005) Pharm Res , vol.22 , pp. 373-380
    • Thomas, M.1    Ge, Q.2    Lu, J.J.3
  • 49
    • 20444488293 scopus 로고    scopus 로고
    • Physicochemical characterization of poly (L-lactic acid) and poly(D,L-lactide-coglycolide) nanoparticles with polyethylenimine as gene delivery carrier
    • Kim IS, Lee SK, Park YM, et al. Physicochemical characterization of poly (L-lactic acid) and poly(D,L-lactide-coglycolide) nanoparticles with polyethylenimine as gene delivery carrier. Int J Pharm 2005;298:255-262
    • (2005) Int J Pharm , vol.298 , pp. 255-262
    • Kim, I.S.1    Lee, S.K.2    Park, Y.M.3
  • 50
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet P, Favrot MC, Hurbin A, et al. Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J Gene Med 2002;4:84-91
    • (2002) J Gene Med , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3
  • 51
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly(ethylenimine)- mediated cytotoxicity: Implications for gene transfer/therapy
    • Moghimi SM, Symonds P, Murray JC, et al. A two-stage poly(ethylenimine)- mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 2005;11:990-995
    • (2005) Mol Ther , vol.11 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3
  • 52
    • 0032821886 scopus 로고    scopus 로고
    • Improved packing of poly (ethyleneimine)/DNA complexes increases transfection efficiency
    • Godbey WT, Wu KK, Hirasaki GJ, Mikos AG. Improved packing of poly (ethyleneimine)/DNA complexes increases transfection efficiency. Gene Ther 1999;6:1380-1388
    • (1999) Gene Ther , vol.6 , pp. 1380-1388
    • Godbey, W.T.1    Wu, K.K.2    Hirasaki, G.J.3    Mikos, A.G.4
  • 53
    • 0035284549 scopus 로고    scopus 로고
    • Poly (ethyleneimine)-mediated gene delivery affects endothelial cell function and viability
    • Godbey WT, Wu KK, Mikos AG. Poly (ethyleneimine)-mediated gene delivery affects endothelial cell function and viability. Biomaterials 2001;22:471-480
    • (2001) Biomaterials , vol.22 , pp. 471-480
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 54
    • 0038004448 scopus 로고    scopus 로고
    • A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity
    • Fischer D, Bieber T, Li Y, et al. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 1999;16:1273-1279
    • (1999) Pharm Res , vol.16 , pp. 1273-1279
    • Fischer, D.1    Bieber, T.2    Li, Y.3
  • 55
    • 21744445582 scopus 로고    scopus 로고
    • Degradable polyethylenimine-altpoly (ethylene glycol) copolymers as novel gene carriers
    • Park MR, Han KO, Han IK, et al. Degradable polyethylenimine-altpoly (ethylene glycol) copolymers as novel gene carriers. J Control Release 2005;105:367-380
    • (2005) J Control Release , vol.105 , pp. 367-380
    • Park, M.R.1    Han, K.O.2    Han, I.K.3
  • 56
    • 28844486084 scopus 로고    scopus 로고
    • Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)- b-polyethylenimine triblock copolymers: Synthesis, characterization, and in vitro gene transfer properties
    • Zhong Z, Feijen J, Lok MC, et al. Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)- b-polyethylenimine triblock copolymers: synthesis, characterization, and in vitro gene transfer properties. Biomacromolecules 2005; 6:3440-3448
    • (2005) Biomacromolecules , vol.6 , pp. 3440-3448
    • Zhong, Z.1    Feijen, J.2    Lok, M.C.3
  • 57
    • 33745700159 scopus 로고    scopus 로고
    • One-pot synthesis of a polyrotaxane via selective threading of a PEI-b-PEG-b-PEI copolymer
    • Choi HS, Ooya T, Yui N. One-pot synthesis of a polyrotaxane via selective threading of a PEI-b-PEG-b-PEI copolymer. Macromol Biosci 2006;6:420-424
    • (2006) Macromol Biosci , vol.6 , pp. 420-424
    • Choi, H.S.1    Ooya, T.2    Yui, N.3
  • 58
    • 0142072936 scopus 로고    scopus 로고
    • Novel shielded transferrin polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer
    • Kursa M, Walker GF, Roessler V, et al. Novel shielded transferrin polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer. Bioconjug Chem 2003;14:222-231
    • (2003) Bioconjug Chem , vol.14 , pp. 222-231
    • Kursa, M.1    Walker, G.F.2    Roessler, V.3
  • 59
    • 0033084717 scopus 로고    scopus 로고
    • Polycation-based DNA complexes for tumor-targeted gene delivery in vivo
    • Kircheis R, Schuller S, Brunner S, et al. Polycation-based DNA complexes for tumor-targeted gene delivery in vivo. J Gene Med 1999;1:111-120
    • (1999) J Gene Med , vol.1 , pp. 111-120
    • Kircheis, R.1    Schuller, S.2    Brunner, S.3
  • 60
    • 77953840181 scopus 로고    scopus 로고
    • Polycationic nanoparticles as non-viral vectors employed for gene therapy in vivo
    • Xing J, Deng L, Guo S, et al. Polycationic nanoparticles as non-viral vectors employed for gene therapy in vivo. Mini Rev Med Chem 2010;10(2):126-137
    • (2010) Mini Rev Med Chem , vol.10 , Issue.2 , pp. 126-137
    • Xing, J.1    Deng, L.2    Guo, S.3
  • 61
    • 0036179935 scopus 로고    scopus 로고
    • Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments
    • Merdan T, Kunath K, Fischer D, et al. Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments. Pharm Res 2002;19:140-146
    • (2002) Pharm Res , vol.19 , pp. 140-146
    • Merdan, T.1    Kunath, K.2    Fischer, D.3
  • 62
    • 0032580453 scopus 로고    scopus 로고
    • Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids
    • Pouton CW, Lucas P, Thomas BJ, et al. Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids. J Control Release 1998;53:289-299
    • (1998) J Control Release , vol.53 , pp. 289-299
    • Pouton, C.W.1    Lucas, P.2    Thomas, B.J.3
  • 63
    • 0030886287 scopus 로고    scopus 로고
    • A nonviral vector system for efficient gene transfer to corneal endothelial cells via membrane integrins
    • Shewring L, Collins L, Lightman SL, et al. A nonviral vector system for efficient gene transfer to corneal endothelial cells via membrane integrins. Transplantation 1997;64:763-769
    • (1997) Transplantation , vol.64 , pp. 763-769
    • Shewring, L.1    Collins, L.2    Lightman, S.L.3
  • 64
    • 0035871674 scopus 로고    scopus 로고
    • Systemic circulation of poly(L-lysine)/ DNA vectors is influenced by polycation molecular weight and type of DNA: Differential circulation in mice and rats and the implications for human gene therapy
    • Ward CM, Read ML, Seymour LW. Systemic circulation of poly(L-lysine)/ DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy. Blood 2001;97:2221-2229
    • (2001) Blood , vol.97 , pp. 2221-2229
    • Ward, C.M.1    Read, M.L.2    Seymour, L.W.3
  • 65
    • 0032959729 scopus 로고    scopus 로고
    • Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery
    • In vivo behavior of cationic polyplexes
    • Dash PR, Read ML, Barrett LB, et al. Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther 1999;6:643-50 .. In vivo behavior of cationic polyplexes
    • (1999) Gene Ther , vol.6 , pp. 643-650
    • Dash, P.R.1    Read, M.L.2    Barrett, L.B.3
  • 66
    • 0033652541 scopus 로고    scopus 로고
    • Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents
    • Brown MD, Schatzlein A, Brownlie A, et al. Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents. Bioconjug Chem 2000;11:880-891
    • (2000) Bioconjug Chem , vol.11 , pp. 880-891
    • Brown, M.D.1    Schatzlein, A.2    Brownlie, A.3
  • 67
    • 0037122694 scopus 로고    scopus 로고
    • Artery wall binding peptide-poly(ethylene glycol)-grafted-poly(L-lysine)- based gene delivery to artery wall cells
    • Nah JW, Yu L, Han SO, et al. Artery wall binding peptide-poly(ethylene glycol)-grafted-poly(L-lysine)-based gene delivery to artery wall cells. J Control Release 2002;78:273-284
    • (2002) J Control Release , vol.78 , pp. 273-284
    • Nah, J.W.1    Yu, L.2    Han, S.O.3
  • 68
    • 0035803784 scopus 로고    scopus 로고
    • Midoux, Histidine-rich peptides and polymers for nucleic acids delivery
    • Pichon C, Goncalves P. Midoux, Histidine-rich peptides and polymers for nucleic acids delivery. Adv Drug Deliv Rev 2001;53:75-94
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 75-94
    • Pichon, C.1    Goncalves, P.2
  • 69
    • 12244279074 scopus 로고    scopus 로고
    • Physicochemical and biological evaluation of cationic polymethacrylates as vectors for gene delivery
    • Dubruel P, Christiaens B, Vanloo B, et al. Physicochemical and biological evaluation of cationic polymethacrylates as vectors for gene delivery. Eur J Pharm Sci 2003;18:211-220
    • (2003) Eur J Pharm Sci , vol.18 , pp. 211-220
    • Dubruel, P.1    Christiaens, B.2    Vanloo, B.3
  • 70
    • 1642525686 scopus 로고    scopus 로고
    • Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery
    • Dubruel P, Christiaens B, Rosseneu M, et al. Buffering properties of cationic polymethacrylates are not the only key to successful gene delivery. Biomacromolecules 2004;5:379-388
    • (2004) Biomacromolecules , vol.5 , pp. 379-388
    • Dubruel, P.1    Christiaens, B.2    Rosseneu, M.3
  • 71
    • 0037195303 scopus 로고    scopus 로고
    • New route to amphiphilic coreshell polymer nanospheres: Graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino groups
    • Li P, Zhu JM, Sunintaboon P, et al. New route to amphiphilic coreshell polymer nanospheres: graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino groups. Langmuir 2002;18:8641-8646
    • (2002) Langmuir , vol.18 , pp. 8641-8646
    • Li, P.1    Zhu, J.M.2    Sunintaboon, P.3
  • 72
    • 33644630054 scopus 로고    scopus 로고
    • Intracellular uptake and release of poly (ethyleneimine)-co-poly(methyl methacrylate) nanoparticle/ pDNA complexes for gene delivery
    • Feng M, Lee D, Li P. Intracellular uptake and release of poly (ethyleneimine)-co-poly(methyl methacrylate) nanoparticle/ pDNA complexes for gene delivery. Int J Pharm 2006;311:209-214
    • (2006) Int J Pharm , vol.311 , pp. 209-214
    • Feng, M.1    Lee, D.2    Li, P.3
  • 73
    • 34548818764 scopus 로고    scopus 로고
    • Cationic lipids and polymers mediated vectors for delivery of siRNA
    • Zhang S, Zhao B, Jiang H, et al. Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 2007;123:1-10
    • (2007) J Control Release , vol.123 , pp. 1-10
    • Zhang, S.1    Zhao, B.2    Jiang, H.3
  • 74
    • 46549090126 scopus 로고    scopus 로고
    • Progress in developing cationic vectors for non-viral systemic gene therapy against cancer
    • Morille M, Passirani C, Vonarbaourg A, et al. Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials 2008;29:3477-3496
    • (2008) Biomaterials , vol.29 , pp. 3477-3496
    • Morille, M.1    Passirani, C.2    Vonarbaourg, A.3
  • 75
    • 0035970032 scopus 로고    scopus 로고
    • Polymer-plexes based gene delivery with low cytotoxicity by a unique balance of side-chain termini
    • Putnam D, Gentry CA, Pack DW, Langer R. Polymer-plexes based gene delivery with low cytotoxicity by a unique balance of side-chain termini. Proc Natl Acad Sci USA 2001;98(3):1200-1205
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.3 , pp. 1200-1205
    • Putnam, D.1    Gentry, C.A.2    Pack, D.W.3    Langer, R.4
  • 76
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan T, Kopecek J, Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev 2002;54:715-758
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 77
    • 0033105151 scopus 로고    scopus 로고
    • Cyclodextrins in peptide and protein delivery
    • Irie T, Uekama K. Cyclodextrins in peptide and protein delivery. Adv Drug Deliv Rev 1999;36(1):101-123
    • (1999) Adv Drug Deliv Rev , vol.36 , Issue.1 , pp. 101-123
    • Irie, T.1    Uekama, K.2
  • 78
    • 33645331847 scopus 로고    scopus 로고
    • Cyclodextrin rotaxanes and polyrotaxanes
    • Wenz G, Han BH, Muller A. Cyclodextrin rotaxanes and polyrotaxanes. Chem Rev 2006;106(3):782-817
    • (2006) Chem Rev , vol.106 , Issue.3 , pp. 782-817
    • Wenz, G.1    Han, B.H.2    Muller, A.3
  • 79
    • 20444485849 scopus 로고    scopus 로고
    • Preparation of alpha-cyclodextrin-terminated polyrotaxane consisting of beta-cyclodextrins and pluronic as a building block of a biodegradable network
    • Ooya T, Ito A, Yui N. Preparation of alpha-cyclodextrin-terminated polyrotaxane consisting of beta-cyclodextrins and pluronic as a building block of a biodegradable network. Macromol Biosci 2005;5(5):379-383
    • (2005) Macromol Biosci , vol.5 , Issue.5 , pp. 379-383
    • Ooya, T.1    Ito, A.2    Yui, N.3
  • 80
    • 33749561397 scopus 로고    scopus 로고
    • Synthesis, characterization, and pH-triggered dethreading of alphacyclodextrin- poly(ethylene glycol) polyrotaxanes bearing cleavable endcaps
    • Loethen S, Ooya T, Choi HS, et al. Synthesis, characterization, and pH-triggered dethreading of alphacyclodextrin- poly(ethylene glycol) polyrotaxanes bearing cleavable endcaps. Biomacromolecules 2006;7(9):2501-2506
    • (2006) Biomacromolecules , vol.7 , Issue.9 , pp. 2501-2506
    • Loethen, S.1    Ooya, T.2    Choi, H.S.3
  • 81
    • 14244265907 scopus 로고    scopus 로고
    • Cyclodextrin-polyethylenimine conjugates for targeted in vitro gene delivery
    • Forrest ML, Gabrielson N, Pack DW. Cyclodextrin-polyethylenimine conjugates for targeted in vitro gene delivery. Biotechnol Bioeng 2005;89(4):416-423
    • (2005) Biotechnol Bioeng , vol.89 , Issue.4 , pp. 416-423
    • Forrest, M.L.1    Gabrielson, N.2    Pack, D.W.3
  • 82
    • 33745265648 scopus 로고    scopus 로고
    • Low molecular weight polyethylenimines linked by betacyclodextrin for gene transfer into the nervous system
    • Tang GP, Guo HY, Alexis F, et al. Low molecular weight polyethylenimines linked by betacyclodextrin for gene transfer into the nervous system. J Gene Med 2006;8(6):736-744
    • (2006) J Gene Med , vol.8 , Issue.6 , pp. 736-744
    • Tang, G.P.1    Guo, H.Y.2    Alexis, F.3
  • 83
    • 34247523833 scopus 로고    scopus 로고
    • Cationic star polymers consisting of a cyclodextrin core and oligoethylenimine arms as nonviral gene delivery vectors
    • Yang C, Li HZ, Goh SH, Li J. Cationic star polymers consisting of a cyclodextrin core and oligoethylenimine arms as nonviral gene delivery vectors. Biomaterials 2007;28:3245-3254
    • (2007) Biomaterials , vol.28 , pp. 3245-3254
    • Yang, C.1    Li, H.Z.2    Goh, S.H.3    Li, J.4
  • 84
    • 36649025900 scopus 로고    scopus 로고
    • Synthesis and characterization of polyrotaxanes consisting of cationic alpha-cyclodextrin threaded on poly[(ethylene oxide)-ran- (propylene oxide)] as gene carriers
    • Yang C, Wang X, Li HZ, et al. Synthesis and characterization of polyrotaxanes consisting of cationic alpha-cyclodextrin threaded on poly[(ethylene oxide)-ran- (propylene oxide)] as gene carriers. Biomacromolecules 2007;8:3365-3374
    • (2007) Biomacromolecules , vol.8 , pp. 3365-3374
    • Yang, C.1    Wang, X.2    Li, H.Z.3
  • 85
    • 58149202443 scopus 로고    scopus 로고
    • Tailoring beta-cyclodextrin for DNA delivery by homogeneous functionalization at the secondary face
    • Ortega-Caballero F, Ortiz Mellet C, Le Gourrierec L, et al. Tailoring beta-cyclodextrin for DNA delivery by homogeneous functionalization at the secondary face. Org Lett 2008;10(22):5143-5146
    • (2008) Org Lett , vol.10 , Issue.22 , pp. 5143-5146
    • Ortega-Caballero, F.1    Ortiz Mellet, C.2    Le Gourrierec, L.3
  • 86
    • 67549086371 scopus 로고    scopus 로고
    • Preorganized macromolecular gene delivery systems: Amphiphilic beta-cyclodextrin 'click clusters'
    • Mendez-Ardoy A, Gomez-Garcia M, Ortiz Mellet C. Preorganized macromolecular gene delivery systems: amphiphilic beta-cyclodextrin 'click clusters'. Org Biomol Chem 2009;7:2681-2684
    • (2009) Org Biomol Chem , vol.7 , pp. 2681-2684
    • Mendez-Ardoy, A.1    Gomez-Garcia, M.2    Ortiz Mellet, C.3
  • 87
    • 71549120375 scopus 로고    scopus 로고
    • Polycationic amphiphilic cyclodextrins for gene delivery: Synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity and gene expression
    • Diaz-Moscoso A, Le Gourrierec L, Gomez-Garcia M, et al. Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity and gene expression. Chem Eur J 2010;15(46):12871-12878
    • (2010) Chem Eur J , vol.15 , Issue.46 , pp. 12871-12878
    • Diaz-Moscoso, A.1    Le Gourrierec, L.2    Gomez-Garcia, M.3
  • 88
    • 46749091249 scopus 로고    scopus 로고
    • Rational design of cationic cyclooligosaccharides as efficient gene delivery systems
    • Diaz-Moscoso A, Balbuena P, Gomez-Garcia M, et al. Rational design of cationic cyclooligosaccharides as efficient gene delivery systems. Chem Commun 2008;17:2001-2003
    • (2008) Chem Commun , vol.17 , pp. 2001-2003
    • Diaz-Moscoso, A.1    Balbuena, P.2    Gomez-Garcia, M.3
  • 89
    • 0034623567 scopus 로고    scopus 로고
    • Degradable Poly (beta-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA
    • Lynn D, Langer R. Degradable Poly (beta-amino esters): synthesis, characterization, and self-assembly with plasmid DNA. J Am Chem Soc 2000;122:10761-10768
    • (2000) J Am Chem Soc , vol.122 , pp. 10761-10768
    • Lynn, D.1    Langer, R.2
  • 90
    • 3042716509 scopus 로고    scopus 로고
    • Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines
    • Little SR, Lynn DM, Ge Q, et al. Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci USA 2004;101:9534-9539
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9534-9539
    • Little, S.R.1    Lynn, D.M.2    Ge, Q.3
  • 91
    • 25844443694 scopus 로고    scopus 로고
    • Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery
    • Little SR, Lynn DM, Puram SV, et al. Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery. J Control Release 2005;107:449-462
    • (2005) J Control Release , vol.107 , pp. 449-462
    • Little, S.R.1    Lynn, D.M.2    Puram, S.V.3
  • 92
    • 29244441966 scopus 로고    scopus 로고
    • Poly(ethylene oxide) modified poly(betaaminoester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: Part 2. in vivo distribution and tumor localization studies
    • Shenoy D, Little S, Langer R, Amiji M. Poly(ethylene oxide) modified poly(betaaminoester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 2. In vivo distribution and tumor localization studies. Pharm Res 2005;22(12):2107-2114
    • (2005) Pharm Res , vol.22 , Issue.12 , pp. 2107-2114
    • Shenoy, D.1    Little, S.2    Langer, R.3    Amiji, M.4
  • 93
    • 58849095012 scopus 로고    scopus 로고
    • Evaluation of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells
    • Yatav S, van Vlerken LE, Little SR, Amiji MM. Evaluation of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells. Cancer Chemother Pharmacol 2009;63:711-722
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 711-722
    • Yatav, S.1    Van Vlerken, L.E.2    Little, S.R.3    Amiji, M.M.4
  • 94
    • 51049089558 scopus 로고    scopus 로고
    • Biodistribution and pharmacokinetic analysis of paclitaxel and ceramide administration in multifunctional polymer-blend nanoparticles in drug resistant breast cancer model
    • van Vlerken LE, Duan Z, Little SR, et al. Biodistribution and pharmacokinetic analysis of paclitaxel and ceramide administration in multifunctional polymer-blend nanoparticles in drug resistant breast cancer model. Mol Pharm 2008;5(4):516-526
    • (2008) Mol Pharm , vol.5 , Issue.4 , pp. 516-526
    • Van Vlerken, L.E.1    Duan, Z.2    Little, S.R.3
  • 95
    • 33846300337 scopus 로고    scopus 로고
    • Poly(ethylene oxide) modified poly(betaaminoester) nanoparticles as a pH-sensitive system for tumor targeted delivery of hydrophobic drugs. Part 3. Therapeutic efficacy and safety studies in ovarian cancer xenograft model
    • Devalapally H, Shenoy D, Little S, et al. Poly(ethylene oxide) modified poly(betaaminoester) nanoparticles as a pH-sensitive system for tumor targeted delivery of hydrophobic drugs. Part 3. Therapeutic efficacy and safety studies in ovarian cancer xenograft model. Cancer Chemother Pharmacol 2007;59:477-484
    • (2007) Cancer Chemother Pharmacol , vol.59 , pp. 477-484
    • Devalapally, H.1    Shenoy, D.2    Little, S.3
  • 96
    • 54049107594 scopus 로고    scopus 로고
    • Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery
    • Xiong XB, Uludaǧ H, Lavasanifar A. Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery. Biomaterials 2009;30:242-253
    • (2009) Biomaterials , vol.30 , pp. 242-253
    • Xiong, X.B.1    Uludaǧ, H.2    Lavasanifar, A.3
  • 97
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of cationic liposome mediated gene delivery by polycations
    • Gao X, Huang L. Potentiation of cationic liposome mediated gene delivery by polycations. Biochemistry 1996;35:1027-1036
    • (1996) Biochemistry , vol.35 , pp. 1027-1036
    • Gao, X.1    Huang, L.2
  • 98
    • 0030015493 scopus 로고    scopus 로고
    • Formation of stable cationic lipid/ DNA complexes for gene transfer
    • Hofland HE, Shephard L, Sullivan SM. Formation of stable cationic lipid/ DNA complexes for gene transfer. Proc Natl Acad Sci USA 1996;93:7305-7309
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7305-7309
    • Hofland, H.E.1    Shephard, L.2    Sullivan, S.M.3
  • 99
    • 0023447237 scopus 로고
    • PH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse
    • Wang CY, Huang L. pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse. Proc Natl Acad Sci USA 1987;84:7851-7855
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7851-7855
    • Wang, C.Y.1    Huang, L.2
  • 100
    • 0033793794 scopus 로고    scopus 로고
    • Receptor-specific delivery of liposomes via folate-PEG-chol
    • Guo W, Lee T, Sudimack J, Lee RJ. Receptor-specific delivery of liposomes via folate-PEG-chol. J Liposome Res 2000;10:179-195
    • (2000) J Liposome Res , vol.10 , pp. 179-195
    • Guo, W.1    Lee, T.2    Sudimack, J.3    Lee, R.J.4
  • 101
    • 0035816146 scopus 로고    scopus 로고
    • Tumor-targeted p53-gene therapy enhances the efficacy of conventional chemo/radiotherapy
    • Xu L, Pirollo KF, Chang EH. Tumor-targeted p53-gene therapy enhances the efficacy of conventional chemo/radiotherapy. J Control Release 2001;74:115-128
    • (2001) J Control Release , vol.74 , pp. 115-128
    • Xu, L.1    Pirollo, K.F.2    Chang, E.H.3
  • 102
    • 33847099637 scopus 로고    scopus 로고
    • Lipid-based nanoparticles of nucleic acid delivery
    • Li W, Szoka FC. Lipid-based nanoparticles of nucleic acid delivery. Pharm Res 2007;24(3):438-449
    • (2007) Pharm Res , vol.24 , Issue.3 , pp. 438-449
    • Li, W.1    Szoka, F.C.2
  • 103
    • 0033122136 scopus 로고    scopus 로고
    • Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
    • Van deWetering P, Schuurmans-Nieuwenbroek NM, Hennink WE, Storm G. Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. J Gene Med 1999;1:156-165
    • (1999) J Gene Med , vol.1 , pp. 156-165
    • Van De Wetering, P.1    Schuurmans-Nieuwenbroek, N.M.2    Hennink, W.E.3    Storm, G.4
  • 104
    • 0029801424 scopus 로고    scopus 로고
    • Characterization of vectors for gene therapy formed by self assembly of DNA with synthetic block co-polymers
    • Wolfert MA, Schaht EH, Tonceva V, et al. Characterization of vectors for gene therapy formed by self assembly of DNA with synthetic block co-polymers. Hum Gene Ther 1996;7:2123-2133
    • (1996) Hum Gene Ther , vol.7 , pp. 2123-2133
    • Wolfert, M.A.1    Schaht, E.H.2    Tonceva, V.3
  • 105
    • 0032211994 scopus 로고    scopus 로고
    • Delivery of antisense oligonucleotides using HPMA polymer: Synthesis of A thiol polymer and its conjugation to water-soluble molecules
    • Wang L, Kristensen J, Ruffner DE. Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules. Bioconjug Chem 1998;9:749-757
    • (1998) Bioconjug Chem , vol.9 , pp. 749-757
    • Wang, L.1    Kristensen, J.2    Ruffner, D.E.3
  • 106
    • 52549085121 scopus 로고    scopus 로고
    • The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells
    • Jensen KD, Kopeckova P, Bridge JHB, Kopecek J. The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells. AAPS Pharm Sci 2001;3(4):62-75
    • (2001) AAPS Pharm Sci , vol.3 , Issue.4 , pp. 62-75
    • Jensen, K.D.1    Kopeckova, P.2    Jhb, B.3    Kopecek, J.4
  • 107
    • 31544441351 scopus 로고    scopus 로고
    • Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl) methacrylamide]
    • Subr V, Konak C, Laga R, Ulbrich K. Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl) methacrylamide]. Biomacromolecules 2006;7:122-130
    • (2006) Biomacromolecules , vol.7 , pp. 122-130
    • Subr, V.1    Konak, C.2    Laga, R.3    Ulbrich, K.4
  • 108
    • 33750288634 scopus 로고    scopus 로고
    • Corona-stabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization
    • Scales CW, Huang F, Li N, et al. Corona-stabilized interpolyelectrolyte complexes of siRNA with nonimmunogenic, hydrophilic/cationic block copolymers prepared by aqueous RAFT polymerization. Macromolecules 2006;39:6871-6881
    • (2006) Macromolecules , vol.39 , pp. 6871-6881
    • Scales, C.W.1    Huang, F.2    Li, N.3
  • 109
    • 38549103632 scopus 로고    scopus 로고
    • Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles
    • Li SD, Chono S, Huang L. Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles. J Control Release 2008;126(1):77-84
    • (2008) J Control Release , vol.126 , Issue.1 , pp. 77-84
    • Li, S.D.1    Chono, S.2    Huang, L.3
  • 111
    • 27644542061 scopus 로고    scopus 로고
    • Medical application of magnetic functionalized nanoparticles
    • Ito A, Shinkai M, Honda H, Kobayashi T. Medical application of magnetic functionalized nanoparticles. J Biosci Eng 2005;10(1):1-11
    • (2005) J Biosci Eng , vol.10 , Issue.1 , pp. 1-11
    • Ito, A.1    Shinkai, M.2    Honda, H.3    Kobayashi, T.4
  • 112
    • 0029906893 scopus 로고    scopus 로고
    • Intracellular hyperthermia for cancer using magnetite cationic liposome: In vitro study
    • Shinkai M, Yanase M, Honda H, et al. Intracellular hyperthermia for cancer using magnetite cationic liposome: in vitro study. Jpn J Cancer Res 1996;87:1179-1183
    • (1996) Jpn J Cancer Res , vol.87 , pp. 1179-1183
    • Shinkai, M.1    Yanase, M.2    Honda, H.3
  • 113
    • 0038580784 scopus 로고    scopus 로고
    • Anticancer effect and immune induction by hyperthermia of malignant melanoma using magnetite cationic liposomes
    • Suzuki M, Shinkai M, Honda H, Kobayashi T. Anticancer effect and immune induction by hyperthermia of malignant melanoma using magnetite cationic liposomes. Melanoma Res 2003;13:129-135
    • (2003) Melanoma Res , vol.13 , pp. 129-135
    • Suzuki, M.1    Shinkai, M.2    Honda, H.3    Kobayashi, T.4
  • 115
    • 6944230808 scopus 로고    scopus 로고
    • Hyperthermia using magnetite cationic liposomes for hamster osteosarcoma
    • Matsuoka F, Shinkai M, Honda H, et al. Hyperthermia using magnetite cationic liposomes for hamster osteosarcoma. Biomagn Res Technol 2004;2(3):1-6
    • (2004) Biomagn Res Technol , vol.2 , Issue.3 , pp. 1-6
    • Matsuoka, F.1    Shinkai, M.2    Honda, H.3
  • 116
    • 0142009392 scopus 로고    scopus 로고
    • Interstitial hyperthermia using magnetite cationic liposomes inhibit to tumor growth of VX-7 transplanted tumor in rabbit tongue
    • Matsuno H, Tohnai I, Mitsudo K, et al. Interstitial hyperthermia using magnetite cationic liposomes inhibit to tumor growth of VX-7 transplanted tumor in rabbit tongue. Jpn J Hyperthermic Oncol 2001;17:141-149
    • (2001) Jpn J Hyperthermic Oncol , vol.17 , pp. 141-149
    • Matsuno, H.1    Tohnai, I.2    Mitsudo, K.3
  • 117
    • 63849304521 scopus 로고    scopus 로고
    • Cationic polybutylcyanoacrylate nanoparticles for DNA delivery
    • doi:10.1155/2009/149254
    • Duan J, Zhang Y, Chen W, et al. Cationic polybutylcyanoacrylate nanoparticles for DNA delivery. J Biomed Biotechnol 2009; doi:10.1155/2009/ 149254
    • (2009) J Biomed Biotechnol
    • Duan, J.1    Zhang, Y.2    Chen, W.3
  • 118
    • 33846169452 scopus 로고    scopus 로고
    • Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: Safety and efficacy in xenografted aggressive breast cancer
    • Pille JY, Li H, Blot E, et al. Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer. Hum Gene Ther 2006;17:1019-1026
    • (2006) Hum Gene Ther , vol.17 , pp. 1019-1026
    • Pille, J.Y.1    Li, H.2    Blot, E.3
  • 119
    • 0034096471 scopus 로고    scopus 로고
    • Formation of positively charged poly (butyl cyanoacrylate) nanoparticles stabilized with chitosan
    • Yang SC, Ge HX, Hu Y, et al. Formation of positively charged poly (butyl cyanoacrylate) nanoparticles stabilized with chitosan. Colloid Polym Sci 2000;278:285-292
    • (2000) Colloid Polym Sci , vol.278 , pp. 285-292
    • Yang, S.C.1    Ge, H.X.2    Hu, Y.3
  • 120
    • 62749096766 scopus 로고    scopus 로고
    • Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors
    • Bilensoy E, Sarisözen C, Esendaǧli G, et al. Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors. Int J Pharm 2009;371:170-176
    • (2009) Int J Pharm , vol.371 , pp. 170-176
    • Bilensoy, E.1    Sarisözen, C.2    Esendaǧli, G.3
  • 121
    • 63249095325 scopus 로고    scopus 로고
    • Effect of molecular structure of cationic surfactants on biophysical interactions of surfactant-modified nanoparticles with a model membrane and cellular uptake
    • Peetla C, Labhasetwar V. Effect of molecular structure of cationic surfactants on biophysical interactions of surfactant-modified nanoparticles with a model membrane and cellular uptake. Langmuir 2009;25:2369-2377
    • (2009) Langmuir , vol.25 , pp. 2369-2377
    • Peetla, C.1    Labhasetwar, V.2
  • 122
    • 70350244685 scopus 로고    scopus 로고
    • PLGA nanoparticles stabilized with a cationic surfactant: Safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat
    • Bhardwaj V, Ankola DD, Gupta SC, et al. PLGA nanoparticles stabilized with a cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat. Pharm Res 2009;26(11):2495-2503
    • (2009) Pharm Res , vol.26 , Issue.11 , pp. 2495-2503
    • Bhardwaj, V.1    Ankola, D.D.2    Gupta, S.C.3
  • 123
    • 77951276022 scopus 로고    scopus 로고
    • Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells
    • Baoum A, Dhillon N, Buch S, Berkland C. Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells. J Pharm Sci 2010;99(5):2413-2422
    • (2010) J Pharm Sci , vol.99 , Issue.5 , pp. 2413-2422
    • Baoum, A.1    Dhillon, N.2    Buch, S.3    Berkland, C.4
  • 124
    • 59449091692 scopus 로고    scopus 로고
    • In vivo targeted gene delivery by cationic nanparticles for treatment of hepatocellular carcinoma
    • Diaz S, Navarro G, Tros de Ilarduya C, et al. In vivo targeted gene delivery by cationic nanparticles for treatment of hepatocellular carcinoma. J Gene Med 2009;11:38-45
    • (2009) J Gene Med , vol.11 , pp. 38-45
    • Diaz, S.1    Navarro, G.2    Tros De Ilarduya, C.3
  • 125
    • 63449093837 scopus 로고    scopus 로고
    • Targeted cationic Poly(D,L-Lactic- Co-Glycolic Acid) nanoparticles for gene delivery to cultured cells
    • Diez S, Migueliz G, Tros de Ilarduya C, et al. Targeted cationic Poly(D,L-Lactic- Co-Glycolic Acid) nanoparticles for gene delivery to cultured cells. Cell Mol Biol Lett 2009;14:347-362
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 347-362
    • Diez, S.1    Migueliz, G.2    Tros De Ilarduya, C.3
  • 126
    • 12844258906 scopus 로고    scopus 로고
    • Dendrimers and dendritic polymers in drug delivery
    • Gillies R, Frechet JMJ. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 2005;10(1):35-43
    • (2005) Drug Discov Today , vol.10 , Issue.1 , pp. 35-43
    • Gillies, R.1    Jmj, F.2
  • 127
    • 28744437107 scopus 로고    scopus 로고
    • Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex
    • Patri AK, Kukowska-Latallo JF, Baker JR Jr. Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. Adv Drug Deliv Rev 2005;57:2203-2214
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 2203-2214
    • Patri, A.K.1    Kukowska-Latallo, J.F.2    Baker Jr., J.R.3
  • 129
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery systems
    • Luo D, Saltzman WM. Synthetic DNA delivery systems. Nat Biotechnol 2000;18(1):33-37
    • (2000) Nat Biotechnol , vol.18 , Issue.1 , pp. 33-37
    • Luo, D.1    Saltzman, W.M.2
  • 130
    • 0036363610 scopus 로고    scopus 로고
    • Jet nebulization of PEI/DNA polyplexes: Physical stability and in vitro gene delivery efficiency
    • Rudolph C, Muller RH, Rosenecker J. Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency. J Gene Med 2002;4(1):66-74
    • (2002) J Gene Med , vol.4 , Issue.1 , pp. 66-74
    • Rudolph, C.1    Muller, R.H.2    Rosenecker, J.3
  • 131
    • 0024832481 scopus 로고
    • Cloning of cDNA from induced K562 cells which can activate globin gene expression
    • Wu YJ, Noguchi CT. Cloning of cDNA from induced K562 cells which can activate globin gene expression. Prog Clin Biol Res 1989;316A:313-321
    • (1989) Prog Clin Biol Res , vol.316 A , pp. 313-321
    • Wu, Y.J.1    Noguchi, C.T.2
  • 132
    • 0030866647 scopus 로고    scopus 로고
    • Protamine sulfate enhances lipid-mediated gene transfer
    • Sorgi FL, Bhattacharya S, Huang L. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther 1997;4(9):961-968 (Pubitemid 27437722)
    • (1997) Gene Therapy , vol.4 , Issue.9 , pp. 961-968
    • Sorgi, F.L.1    Bhattacharya, S.2    Huang, L.3
  • 133
    • 0032991617 scopus 로고    scopus 로고
    • Synthetic DNA-compacting peptides derived from human sequence enhance cationic lipid-mediated gene transfer in vitro and in vivo
    • Schwartz B, Ivanov MA, Pitard B, et al. Synthetic DNA-compacting peptides derived from human sequence enhance cationic lipid-mediated gene transfer in vitro and in vivo. Gene Ther 1999;6(2):282-292
    • (1999) Gene Ther , vol.6 , Issue.2 , pp. 282-292
    • Schwartz, B.1    Ivanov, M.A.2    Pitard, B.3
  • 134
    • 0025305336 scopus 로고
    • An SV40 large T antigen binding site in the cellular genome is part of a cis-acting transcriptional element
    • Wagner S, Knippers R. An SV40 large T antigen binding site in the cellular genome is part of a cis-acting transcriptional element. Oncogene 1990;5(3):353-359
    • (1990) Oncogene , vol.5 , Issue.3 , pp. 353-359
    • Wagner, S.1    Knippers, R.2
  • 135
    • 0035848402 scopus 로고    scopus 로고
    • In vitro uptake of polystyrene microspheres: Effect of particle size, cell line and cell density
    • Zauner W, Farrow NA, Haines AM. In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density. J Control Release 2001;71(1):39-51
    • (2001) J Control Release , vol.71 , Issue.1 , pp. 39-51
    • Zauner, W.1    Farrow, N.A.2    Haines, A.M.3
  • 136
    • 0032536438 scopus 로고    scopus 로고
    • Effect of serum components on the physico-chemical properties of cationic lipid/ oligonucleotide complexes and on their interactions with cells
    • Zelphati O, Uyechi LS, Barron LG, Szoka FC Jr. Effect of serum components on the physico-chemical properties of cationic lipid/ oligonucleotide complexes and on their interactions with cells. Biochim Biophys Acta 1998;1390(2):119-133
    • (1998) Biochim Biophys Acta , vol.1390 , Issue.2 , pp. 119-133
    • Zelphati, O.1    Uyechi, L.S.2    Barron, L.G.3    Szoka Jr., F.C.4
  • 137
    • 0030775528 scopus 로고    scopus 로고
    • The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
    • Tang MX, Szoka FC. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 1997;4(8):823-832
    • (1997) Gene Ther , vol.4 , Issue.8 , pp. 823-832
    • Tang, M.X.1    Szoka, F.C.2
  • 138
    • 0037072566 scopus 로고    scopus 로고
    • Nanoparticles in cancer therapy and diagnosis
    • Brigger I, Dubernet C, Couvreur P. Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev 2002;54(5):631-651
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.5 , pp. 631-651
    • Brigger, I.1    Dubernet, C.2    Couvreur, P.3
  • 139
    • 85056349819 scopus 로고    scopus 로고
    • Complement activation by injectable colloidal drug carriers
    • Mahato RI, editor, CRC Press, Boca Raton
    • Passirani C. Complement activation by injectable colloidal drug carriers. In: Mahato RI, editor, Biomaterials for delivery and targeting of proteins and nucleic acids. CRC Press, Boca Raton; 2005. p. 187-230
    • (2005) Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids , pp. 187-230
    • Passirani, C.1
  • 140
    • 0023890664 scopus 로고
    • Molecular organization and function of the complement system
    • Muller-Eberhard HJ. Molecular organization and function of the complement system. Annu Rev Biochem 1988;57:321-347
    • (1988) Annu Rev Biochem , vol.57 , pp. 321-347
    • Muller-Eberhard, H.J.1
  • 141
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • Gref R, Minamitake Y, Peracchia MT, et al. Biodegradable long-circulating polymeric nanospheres. Science 1994;263(5153):1600-1603
    • (1994) Science , vol.263 , Issue.5153 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 142
    • 33646384586 scopus 로고    scopus 로고
    • Parameters influencing the stealthiness of colloidal drug delivery systems
    • Vonarbourg A, Passirani C, Saulnier P, Benoit JP. Parameters influencing the stealthiness of colloidal drug delivery systems. Biomaterials 2006;27(24):4356-4373
    • (2006) Biomaterials , vol.27 , Issue.24 , pp. 4356-4373
    • Vonarbourg, A.1    Passirani, C.2    Saulnier, P.3    Benoit, J.P.4
  • 143
    • 43449102775 scopus 로고    scopus 로고
    • Cyclodextrin based supramolecular architectures: Syntheses, structures and application for drug and gene delivery
    • Li J, Loh XJ. Cyclodextrin based supramolecular architectures: syntheses, structures and application for drug and gene delivery. Adv Drug Deliv Rev 2008;60:1000-1017
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1000-1017
    • Li, J.1    Loh, X.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.