Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives

Gene Therapy

Volumn 8, Issue 11, 2001, Pages 855-863

  Gao, H ^a   Hui, K M ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

Cancer gene therapy; Cationic liposomes; Gene delivery; Heterocyclic cholesterol; Serum inactivation

Indexed keywords

CHOLESTEROL DERIVATIVE; DNA; HETEROCYCLIC COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA VECTOR; DRUG ADMINISTRATION; DRUG INACTIVATION; DRUG STRUCTURE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SERUM; SPLEEN; SYNTHESIS; TARGET CELL;

ADENOVIRIDAE; ANIMALS; CATIONS; CELL LINE; CHOLESTEROL; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HUMANS; LIPIDS; LUCIFERASES; MICE; NEOPLASMS; TRANSFECTION;

EID: 0034971315     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301471     Document Type: Article

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