-
1
-
-
32944466762
-
Nanoparticle albumin-bound paclitaxel for metastatic breast cancer
-
Harries M, Ellis P, Harper P: Nanoparticle albumin-bound paclitaxel for metastatic breast cancer. J. Clin. Oncol. 23(31), 7768-7771 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.31
, pp. 7768-7771
-
-
Harries, M.1
Ellis, P.2
Harper, P.3
-
2
-
-
24744443165
-
Nanotechnology blooms, at last (Review)
-
Gordon EM, Hall FL: Nanotechnology blooms, at last (Review). Oncol. Rep. 13(6), 1003-7 (2005).
-
(2005)
Oncol. Rep
, vol.13
, Issue.6
, pp. 1003-1007
-
-
Gordon, E.M.1
Hall, F.L.2
-
3
-
-
34447523146
-
Pathotropic nanoparticles for cancer gene therapy Rexin-G IV: Three-year clinical experience
-
Gordon EM, Lopez FF, Cornelio GH et al.: Pathotropic nanoparticles for cancer gene therapy Rexin-G IV: three-year clinical experience. Int. J. Oncol. 29(5), 1053-1064 (2006).
-
(2006)
Int. J. Oncol
, vol.29
, Issue.5
, pp. 1053-1064
-
-
Gordon, E.M.1
Lopez, F.F.2
Cornelio, G.H.3
-
4
-
-
0034580371
-
The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
-
Jain RA: The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21(23), 2475-2490 (2000).
-
(2000)
Biomaterials
, vol.21
, Issue.23
, pp. 2475-2490
-
-
Jain, R.A.1
-
5
-
-
0343247711
-
Biodegradation and biocompatibility of PLA and PLGA microspheres
-
Shive MS, Anderson JM: Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev. 28(1), 5-24 (1997).
-
(1997)
Adv. Drug Deliv. Rev
, vol.28
, Issue.1
, pp. 5-24
-
-
Shive, M.S.1
Anderson, J.M.2
-
6
-
-
0035816535
-
Drug delivery. Drugs on target
-
Langer R: Drug delivery. Drugs on target. Science 293(5527), 58-59 (2001).
-
(2001)
Science
, vol.293
, Issue.5527
, pp. 58-59
-
-
Langer, R.1
-
7
-
-
33750503424
-
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
-
Cheng J, Teply BA, Sherift I et a.: Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 28(5), 869-876 (2007).
-
(2007)
Biomaterials
, vol.28
, Issue.5
, pp. 869-876
-
-
Cheng, J.1
Teply, B.A.2
Sherift, I.3
et a4
-
8
-
-
0031469673
-
The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent
-
Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon GL: The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm. Res. 14 (11), 1568-1573 (1997).
-
(1997)
Pharm. Res
, vol.14
, Issue.11
, pp. 1568-1573
-
-
Desai, M.P.1
Labhasetwar, V.2
Walter, E.3
Levy, R.J.4
Amidon, G.L.5
-
9
-
-
7444223607
-
Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells
-
Farokhzad OC, Jon S, Khademhosseini A et al.: Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 64(21), 7668-7672 (2004).
-
(2004)
Cancer Res
, vol.64
, Issue.21
, pp. 7668-7672
-
-
Farokhzad, O.C.1
Jon, S.2
Khademhosseini, A.3
-
10
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
-
Desai MP, Labhasetwar V, Amidon GL, Levy RJ: Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm. Res. 13(12), 1838-1845 (1996).
-
(1996)
Pharm. Res
, vol.13
, Issue.12
, pp. 1838-1845
-
-
Desai, M.P.1
Labhasetwar, V.2
Amidon, G.L.3
Levy, R.J.4
-
11
-
-
0035045942
-
Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups
-
Moghimi SM, Hunter AC: Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups. Pharm. Res. 18(1), 1-8 (2001).
-
(2001)
Pharm. Res
, vol.18
, Issue.1
, pp. 1-8
-
-
Moghimi, S.M.1
Hunter, A.C.2
-
12
-
-
0141927263
-
Stealth liposomes and long circulating nanoparticies: Critical issues in pharmacokinetics, opsonization and protein-binding properties
-
Moghimi SM, Szebeni J: Stealth liposomes and long circulating nanoparticies: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog. Lipid Res. 42(6), 463-478 (2003).
-
(2003)
Prog. Lipid Res
, vol.42
, Issue.6
, pp. 463-478
-
-
Moghimi, S.M.1
Szebeni, J.2
-
13
-
-
23444444512
-
Biodegradable long-circulating polymeric nanospheres
-
Gref R, Minamitake Y, Peracchia MT et al.: Biodegradable long-circulating polymeric nanospheres. Science 263(5153), 1600-1603 (1994).
-
(1994)
Science
, vol.263
, Issue.5153
, pp. 1600-1603
-
-
Gref, R.1
Minamitake, Y.2
Peracchia, M.T.3
-
14
-
-
0002407268
-
Nanoparticles for drug delivery
-
Labhasetwar V: Nanoparticles for drug delivery. Pharm. News 4 28-31 (1997).
-
(1997)
Pharm. News
, vol.4
, pp. 28-31
-
-
Labhasetwar, V.1
-
15
-
-
0032767088
-
Biodegradable nanoparticles containing doxorubicin-PLGA conjugate for sustained release
-
Yoo HS, Oh JE, Lee KH, Park TG: Biodegradable nanoparticles containing doxorubicin-PLGA conjugate for sustained release. Pharm. Res. 16(7), 1114-1118 (1999).
-
(1999)
Pharm. Res
, vol.16
, Issue.7
, pp. 1114-1118
-
-
Yoo, H.S.1
Oh, J.E.2
Lee, K.H.3
Park, T.G.4
-
16
-
-
1842638560
-
Folate receptor targeted biodegradable polymeric doxorubicin micelles
-
Yoo HS, Park TG: Folate receptor targeted biodegradable polymeric doxorubicin micelles. J. Control Release 96(2), 273-283 (2004).
-
(2004)
J. Control Release
, vol.96
, Issue.2
, pp. 273-283
-
-
Yoo, H.S.1
Park, T.G.2
-
17
-
-
0037130252
-
Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages
-
Yoo HS, Lee EA, Park TG: Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J. Control Release 82 (1), 17-27 (2002).
-
(2002)
J. Control Release
, vol.82
, Issue.1
, pp. 17-27
-
-
Yoo, H.S.1
Lee, E.A.2
Park, T.G.3
-
18
-
-
0344063545
-
Polyacetal-doxorubicin conjugates designed for pH-dependent degradation
-
Tomlinson R, Heller J, Brocchini S, Duncan R: Polyacetal-doxorubicin conjugates designed for pH-dependent degradation. Bioconjug. Chem. 14(6), 1096-1106 (2003).
-
(2003)
Bioconjug. Chem
, vol.14
, Issue.6
, pp. 1096-1106
-
-
Tomlinson, R.1
Heller, J.2
Brocchini, S.3
Duncan, R.4
-
19
-
-
0037080616
-
Pendant chain functionalized polyacetals that display pH-dependent degradation: A platform for the development of novel polymer therapeutics
-
Tomlinson R, Klee M, Garrett S et al.: Pendant chain functionalized polyacetals that display pH-dependent degradation: a platform for the development of novel polymer therapeutics. Macromolecules 35 473-480 (2002).
-
(2002)
Macromolecules
, vol.35
, pp. 473-480
-
-
Tomlinson, R.1
Klee, M.2
Garrett, S.3
-
20
-
-
0032580354
-
Drug delivery and targeting
-
Langer R: Drug delivery and targeting. Natuir 392(6679 Suppl), 5-10 (1998).
-
(1998)
Natuir
, vol.392
, Issue.6679 SUPPL.
, pp. 5-10
-
-
Langer, R.1
-
21
-
-
0141765877
-
Small-scale systems for in vivo drug delivery
-
LaVan DA, McGuire T, Langer R: Small-scale systems for in vivo drug delivery. Nat. Biotechnol. 21(10), 1184-1191 (2003).
-
(2003)
Nat. Biotechnol
, vol.21
, Issue.10
, pp. 1184-1191
-
-
LaVan, D.A.1
McGuire, T.2
Langer, R.3
-
22
-
-
0037122736
-
Design of biodegradable particles for protein delivery
-
Vila A, Sanchez A, Tobio, M, Calvo, P, Alonso MJ: Design of biodegradable particles for protein delivery. J. Control Release 78(1-3), 15-24 (2002).
-
(2002)
J. Control Release
, vol.78
, Issue.1-3
, pp. 15-24
-
-
Vila, A.1
Sanchez, A.2
Tobio, M.3
Calvo, P.4
Alonso, M.J.5
-
23
-
-
33750059489
-
Chitosan nanocapsules as carriers for oral peptide delivery: Effect of chitosan molecular weight and type of salt on the in vitro behaviour and in vivo effectiveness
-
Prego C, Torres D, Alonso MJ: Chitosan nanocapsules as carriers for oral peptide delivery: effect of chitosan molecular weight and type of salt on the in vitro behaviour and in vivo effectiveness. J. Nanosci. Nanotechnol. 6(9-10), 2921-2928 (2006).
-
(2006)
J. Nanosci. Nanotechnol
, vol.6
, Issue.9-10
, pp. 2921-2928
-
-
Prego, C.1
Torres, D.2
Alonso, M.J.3
-
24
-
-
33847175513
-
Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells
-
Solbrig CM, Saucier-Sawyer JK, Cody V, Saltzman WM, Hanlon DJ: Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells. Mol. Pbarm. 4(1), 47-57 (2007).
-
(2007)
Mol. Pbarm
, vol.4
, Issue.1
, pp. 47-57
-
-
Solbrig, C.M.1
Saucier-Sawyer, J.K.2
Cody, V.3
Saltzman, W.M.4
Hanlon, D.J.5
-
25
-
-
0034777178
-
Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid
-
Raghuvanshi RJ, Mistra A, Talwar GP, Levy RJ, Labhasetwar V: Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid. J. Microencapsul. 18 723-732 (2001).
-
(2001)
J. Microencapsul
, vol.18
, pp. 723-732
-
-
Raghuvanshi, R.J.1
Mistra, A.2
Talwar, G.P.3
Levy, R.J.4
Labhasetwar, V.5
-
26
-
-
33846139668
-
Nanoparticles for two-photon photodynamic therapy in living cells
-
Gao D, Agayan RR, Xu H, Philbert MA, Kopelman R: Nanoparticles for two-photon photodynamic therapy in living cells. Nano Lett. 6(11), 2383-2836 (2006).
-
(2006)
Nano Lett
, vol.6
, Issue.11
, pp. 2383-2836
-
-
Gao, D.1
Agayan, R.R.2
Xu, H.3
Philbert, M.A.4
Kopelman, R.5
-
27
-
-
30644466989
-
Polymeric nanoparticle preparation that eradicates tumors
-
McCarthy JR, Perez JM, Bruckner C, Weissleder R: Polymeric nanoparticle preparation that eradicates tumors. Nano. Lett. 5(12), 2552-2556 (2005).
-
(2005)
Nano. Lett
, vol.5
, Issue.12
, pp. 2552-2556
-
-
McCarthy, J.R.1
Perez, J.M.2
Bruckner, C.3
Weissleder, R.4
-
28
-
-
84950232819
-
Polymeric delivery systems for controlled drug release
-
Langer R: Polymeric delivery systems for controlled drug release. Chem. Eng. Commun. 6 15-48 (1980).
-
(1980)
Chem. Eng. Commun
, vol.6
, pp. 15-48
-
-
Langer, R.1
-
29
-
-
0035844746
-
Mathematical modeling of bioerudible, polymeric drug delivery systems
-
Stepmann J, Gopferich A: Mathematical modeling of bioerudible, polymeric drug delivery systems. Adv. Drug Deliv. Rev. 48(2-3), 229-247 (2001).
-
(2001)
Adv. Drug Deliv. Rev
, vol.48
, Issue.2-3
, pp. 229-247
-
-
Stepmann, J.1
Gopferich, A.2
-
30
-
-
27944508780
-
Polyketal nanoparticles: A new pH-sensitive biodegradable drug delivery vehicle
-
Heffernan MJ, Murthy N: Polyketal nanoparticles: a new pH-sensitive biodegradable drug delivery vehicle. Bioconjug. Chem. 16(6), 1340-1342 (2005).
-
(2005)
Bioconjug. Chem
, vol.16
, Issue.6
, pp. 1340-1342
-
-
Heffernan, M.J.1
Murthy, N.2
-
31
-
-
33846199257
-
Targeted and intracellular delivery of paclitaxel using multi-functional polymeric micelles
-
Seow WY, Xue JM, Yang YY: Targeted and intracellular delivery of paclitaxel using multi-functional polymeric micelles. Biomaterials 28(9), 1730-1840 (2007).
-
(2007)
Biomaterials
, vol.28
, Issue.9
, pp. 1730-1840
-
-
Seow, W.Y.1
Xue, J.M.2
Yang, Y.Y.3
-
32
-
-
27144542045
-
Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs. 1. In vitro evaluations
-
Shenoy D, Little S, Langer R, Amiji M: Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs. 1. In vitro evaluations. Mol. Pharm. 2(5), 357-366 (2005).
-
(2005)
Mol. Pharm
, vol.2
, Issue.5
, pp. 357-366
-
-
Shenoy, D.1
Little, S.2
Langer, R.3
Amiji, M.4
-
33
-
-
0035816166
-
Drug targeting using thermally responsive polymers and local hyperthermia
-
Meyer DE, Shin BC, Kong GA, Dewhirst MW, Chilkoti A, Drug targeting using thermally responsive polymers and local hyperthermia. J. Control, Release 74(1-3), 213-224 (2001).
-
(2001)
J. Control, Release
, vol.74
, Issue.1-3
, pp. 213-224
-
-
Meyer, D.E.1
Shin, B.C.2
Kong, G.A.3
Dewhirst, M.W.4
Chilkoti, A.5
-
34
-
-
33748946595
-
Hyperthermia-induced antitumor activity of thermosensitive polymer modified temperature-sensitive liposomes
-
Han HD, Choi MS, Hwang T et al.: Hyperthermia-induced antitumor activity of thermosensitive polymer modified temperature-sensitive liposomes. J. Pharm. Sci. 95(9), 1909-1917 (2006).
-
(2006)
J. Pharm. Sci
, vol.95
, Issue.9
, pp. 1909-1917
-
-
Han, H.D.1
Choi, M.S.2
Hwang, T.3
-
35
-
-
33745622165
-
Temperature-sensitive pluronic/ poly(ethylenimine) nanocapsules for thermally triggered disruption of intracellular endosomal compartment
-
Choi SH, Lee SH, Park TG: Temperature-sensitive pluronic/ poly(ethylenimine) nanocapsules for thermally triggered disruption of intracellular endosomal compartment. Biomacromolecules 7 (6), 1864-1870 (2006).
-
(2006)
Biomacromolecules
, vol.7
, Issue.6
, pp. 1864-1870
-
-
Choi, S.H.1
Lee, S.H.2
Park, T.G.3
-
36
-
-
23144456813
-
Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
-
Sengupta S, Eavarone D, Capila I et al.: Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature 436(7050), 568-572 (2005).
-
(2005)
Nature
, vol.436
, Issue.7050
, pp. 568-572
-
-
Sengupta, S.1
Eavarone, D.2
Capila, I.3
-
37
-
-
34250303805
-
Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer
-
van Vlerken LE, Duan Z, Seiden MV, Amiji MM: Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer. Cancer Res. 67(10), 4843-4850 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.10
, pp. 4843-4850
-
-
van Vlerken, L.E.1
Duan, Z.2
Seiden, M.V.3
Amiji, M.M.4
-
38
-
-
33645403885
-
Cellpermeable and biocompatible polymeric nanoparticles for apoptosis imaging
-
Kim K, Lee M, Park H et al.: Cellpermeable and biocompatible polymeric nanoparticles for apoptosis imaging. J. Am. Chem. Soc. 128(11), 3490-3491 (2006).
-
(2006)
J. Am. Chem. Soc
, vol.128
, Issue.11
, pp. 3490-3491
-
-
Kim, K.1
Lee, M.2
Park, H.3
-
39
-
-
33746771019
-
Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas
-
Montet X, Weissleder R, Josephson L: Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas. Bioconjug. Chem. 17(4), 905-911 (2006).
-
(2006)
Bioconjug. Chem
, vol.17
, Issue.4
, pp. 905-911
-
-
Montet, X.1
Weissleder, R.2
Josephson, L.3
-
40
-
-
33846160552
-
Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
-
Nasongkla N, Bey E, Ren J et al.: Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano. Lett. 6(11), 2427-2430 (2006).
-
(2006)
Nano. Lett
, vol.6
, Issue.11
, pp. 2427-2430
-
-
Nasongkla, N.1
Bey, E.2
Ren, J.3
-
41
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W et al.: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411(6836), 494-498 (2001).
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
42
-
-
0347365764
-
An overview of current delivery systems in cancer gene therapy
-
El-Aneed A: An overview of current delivery systems in cancer gene therapy. J. Control. Release 94(1), 1-14 (2004).
-
(2004)
J. Control. Release
, vol.94
, Issue.1
, pp. 1-14
-
-
El-Aneed, A.1
-
43
-
-
0035135747
-
Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
-
Kay MA, Glorioso JC, Naldini L: Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat. Med. 7(1), 33-40 (2001).
-
(2001)
Nat. Med
, vol.7
, Issue.1
, pp. 33-40
-
-
Kay, M.A.1
Glorioso, J.C.2
Naldini, L.3
-
44
-
-
0037072576
-
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
-
Merdan T, Kopecek J, Kissel T: Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv. Drug Deliv. Rev. 54(5), 715-758 (2002).
-
(2002)
Adv. Drug Deliv. Rev
, vol.54
, Issue.5
, pp. 715-758
-
-
Merdan, T.1
Kopecek, J.2
Kissel, T.3
-
45
-
-
14044272234
-
Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters)
-
Anderson DG, Akinc A, Hossain N, Langer R: Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Mol. Ther. 11(3), 426-434 (2005).
-
(2005)
Mol. Ther
, vol.11
, Issue.3
, pp. 426-434
-
-
Anderson, D.G.1
Akinc, A.2
Hossain, N.3
Langer, R.4
-
46
-
-
8644275490
-
A polymer library approach to suicide gene therapy for cancer
-
Anderson DG, Peng W, Akinc A et al.: A polymer library approach to suicide gene therapy for cancer. Proc. Natl Acad. Sci. USA 101(45), 16028-16033 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.45
, pp. 16028-16033
-
-
Anderson, D.G.1
Peng, W.2
Akinc, A.3
-
47
-
-
33749012572
-
Biodegradable polymeric vectors for gene delivery to human endothelial cells
-
Green JJ, Shi J, Chiu E et al.: Biodegradable polymeric vectors for gene delivery to human endothelial cells. Bioconfug. Chem. 17(5), 1162-1169 (2006).
-
(2006)
Bioconfug. Chem
, vol.17
, Issue.5
, pp. 1162-1169
-
-
Green, J.J.1
Shi, J.2
Chiu, E.3
-
48
-
-
25444482607
-
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
-
Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ: Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res. 65(19), 8984-8992 (2005).
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 8984-8992
-
-
Hu-Lieskovan, S.1
Heidel, J.D.2
Bartlett, D.W.3
Davis, M.E.4
Triche, T.J.5
-
49
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers RM, Ansari A, Xu J et al.: Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 32(19), e149 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.19
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
-
50
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A: RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 12(5), 461-466 (2005).
-
(2005)
Gene Ther
, vol.12
, Issue.5
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
51
-
-
33749983751
-
Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
-
Wang Y, Gac, S, Ye WH, Yoon HS, Yang YY: Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat. Mater. 5(10), 791-796 (2006).
-
(2006)
Nat. Mater
, vol.5
, Issue.10
, pp. 791-796
-
-
Wang, Y.1
Gac, S.2
Ye, W.H.3
Yoon, H.S.4
Yang, Y.Y.5
-
52
-
-
0036680012
-
Dendritic polymer macromolecular carriers for drug delivery
-
Patri AK, Majoros IJ, Baker JR: Dendritic polymer macromolecular carriers for drug delivery. Curr. Opin. Chem. Biol. 6(4), 466-471 (2002).
-
(2002)
Curr. Opin. Chem. Biol
, vol.6
, Issue.4
, pp. 466-471
-
-
Patri, A.K.1
Majoros, I.J.2
Baker, J.R.3
-
53
-
-
28644434579
-
Designing dendrimers for biological applications
-
Lee CC, MacKay JA, Frechet JM, Szoka FC: Designing dendrimers for biological applications. Nat. Biotechnol. 23(12). 1517-1526 (2005).
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.12
, pp. 1517-1526
-
-
Lee, C.C.1
MacKay, J.A.2
Frechet, J.M.3
Szoka, F.C.4
-
54
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
Duncan R, Izzo L: Dendrimer biocompatibility and toxicity Adv. Drug Deliv. Rev. 57(15), 2215-2237 (2005).
-
(2005)
Adv. Drug Deliv. Rev
, vol.57
, Issue.15
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
55
-
-
0030042315
-
Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers
-
Roberts JC, Bhalgat MK, Zera RT: Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers. J. Biomed. Mater. Res. 30(1), 53-65 (1996).
-
(1996)
J. Biomed. Mater. Res
, vol.30
, Issue.1
, pp. 53-65
-
-
Roberts, J.C.1
Bhalgat, M.K.2
Zera, R.T.3
-
56
-
-
33750936437
-
A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
-
Lee CC, Gillies ER, Fox ME et al.: A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc. Natl Acad. Sci. USA 103(45), 16649-16654 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.45
, pp. 16649-16654
-
-
Lee, C.C.1
Gillies, E.R.2
Fox, M.E.3
-
57
-
-
0037161405
-
Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
-
Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM: Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery. Macromolecules 35 3456-3462 (2002).
-
(2002)
Macromolecules
, vol.35
, pp. 3456-3462
-
-
Luo, D.1
Haverstick, K.2
Belcheva, N.3
Han, E.4
Saltzman, W.M.5
-
58
-
-
27444439072
-
A Family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gone delivery
-
Wood KC, Little SR, Langer R, Hammond PT. A Family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gone delivery. Angew. Chem. Int. Ed. 44, 6704-6708 (2005).
-
(2005)
Angew. Chem. Int. Ed
, vol.44
, pp. 6704-6708
-
-
Wood, K.C.1
Little, S.R.2
Langer, R.3
Hammond, P.T.4
-
59
-
-
33846456200
-
Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells
-
Myc A, Majoros IJ, Thomas TP, Baker JR Jr: Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. Biomacromolecules 8(1), 13-18 (2007).
-
(2007)
Biomacromolecules
, vol.8
, Issue.1
, pp. 13-18
-
-
Myc, A.1
Majoros, I.J.2
Thomas, T.P.3
Baker Jr, J.R.4
-
60
-
-
33644593095
-
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, functionality
-
Majoros IJ, Myc A, Thomas T, Mehta CB, Baker JR Jr: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, functionality. Biomacromolecules 7(2), 572-579 (2006).
-
(2006)
Biomacromolecules
, vol.7
, Issue.2
, pp. 572-579
-
-
Majoros, I.J.1
Myc, A.2
Thomas, T.3
Mehta, C.B.4
Baker Jr, J.R.5
-
61
-
-
23944434447
-
Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention
-
McCarthy TD, Karetias P, Henderson SA et al.: Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention. Mol. Pharm. 2(4), 312-318 (2005).
-
(2005)
Mol. Pharm
, vol.2
, Issue.4
, pp. 312-318
-
-
McCarthy, T.D.1
Karetias, P.2
Henderson, S.A.3
-
62
-
-
33846393538
-
Synthesis of biocompatible poly[2-(methacryloyloxy)ethylphosphorylcholine]- coated magnetite nanoparticles
-
Yuan JJ, Armes SP, Takabayashi Y et al.: Synthesis of biocompatible poly[2-(methacryloyloxy)ethylphosphorylcholine]- coated magnetite nanoparticles. Langmuir 22(26), 10989-10993 (2006).
-
(2006)
Langmuir
, vol.22
, Issue.26
, pp. 10989-10993
-
-
Yuan, J.J.1
Armes, S.P.2
Takabayashi, Y.3
-
63
-
-
0037373410
-
MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles
-
Artemov D, Mori N, Okollie B, Bhujwalla ZM: MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles. Magn. Reson. Med. 49(3), 403-408 (2003).
-
(2003)
Magn. Reson. Med
, vol.49
, Issue.3
, pp. 403-408
-
-
Artemov, D.1
Mori, N.2
Okollie, B.3
Bhujwalla, Z.M.4
-
64
-
-
0035173736
-
Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent
-
Zhao M, Beauregard DA, Loizou L, Davletov B, Brindle KM: Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat. Med. 7(11), 1241-1244 (2001).
-
(2001)
Nat. Med
, vol.7
, Issue.11
, pp. 1241-1244
-
-
Zhao, M.1
Beauregard, D.A.2
Loizou, L.3
Davletov, B.4
Brindle, K.M.5
-
65
-
-
1642515770
-
Novel nanosensors for rapid analysis of telomerase activity
-
Grimm J, Perez JM, Josephson L, Weissleder R: Novel nanosensors for rapid analysis of telomerase activity. Cancer Res. 64(2), 639-643 (2004).
-
(2004)
Cancer Res
, vol.64
, Issue.2
, pp. 639-643
-
-
Grimm, J.1
Perez, J.M.2
Josephson, L.3
Weissleder, R.4
-
66
-
-
33846545130
-
Biomimetic amplification of nanoparticle homing to tumors
-
Simberg D, Duza T, Park JH et al.: Biomimetic amplification of nanoparticle homing to tumors. Proc. Natl Acad. Sci. USA 104(3), 932-936 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.3
, pp. 932-936
-
-
Simberg, D.1
Duza, T.2
Park, J.H.3
-
67
-
-
0032426610
-
Superparamagnetic agents in magnetic resonance imaging: Physicochemical characteristics and clinical applications. A review
-
Bonnemain B: Superparamagnetic agents in magnetic resonance imaging: physicochemical characteristics and clinical applications. A review. J Drug Target 6(3), 167-174 (1998).
-
(1998)
J Drug Target
, vol.6
, Issue.3
, pp. 167-174
-
-
Bonnemain, B.1
-
68
-
-
0027481138
-
Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia
-
Jordan A, Wust P, Fahling H et al.: Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. Int. J. Hyperthermia 9(1), 51-68 (1993).
-
(1993)
Int. J. Hyperthermia
, vol.9
, Issue.1
, pp. 51-68
-
-
Jordan, A.1
Wust, P.2
Fahling, H.3
-
69
-
-
0036299353
-
Magnetically mediated hyperthermia: Current status and future directions
-
Moroz P, Jones SK, Gray BN: Magnetically mediated hyperthermia: current status and future directions. Int. J. Hyperthermia 18(4), 267-284 (2002)..
-
(2002)
Int. J. Hyperthermia
, vol.18
, Issue.4
, pp. 267-284
-
-
Moroz, P.1
Jones, S.K.2
Gray, B.N.3
-
70
-
-
11044222650
-
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
-
Gupta AK, Gupta M: Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26(18), 3995-4021 (2005).
-
(2005)
Biomaterials
, vol.26
, Issue.18
, pp. 3995-4021
-
-
Gupta, A.K.1
Gupta, M.2
-
71
-
-
34249858538
-
Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial
-
Johannsen M, Gneveckow U, Taymoorian K et al.: Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial. Int. J. Hyperthermia 23(3), 315-323 (2007).
-
(2007)
Int. J. Hyperthermia
, vol.23
, Issue.3
, pp. 315-323
-
-
Johannsen, M.1
Gneveckow, U.2
Taymoorian, K.3
-
72
-
-
33745473776
-
Fluorescence-modified superparamagnetic nanoparticles: Intracellular uptake and use in cellular imaging
-
Bertorelle F, Wilhelm C, Roger J et al.: Fluorescence-modified superparamagnetic nanoparticles: intracellular uptake and use in cellular imaging. Langmuir 22(12), 5385-5391 (2006).
-
(2006)
Langmuir
, vol.22
, Issue.12
, pp. 5385-5391
-
-
Bertorelle, F.1
Wilhelm, C.2
Roger, J.3
-
73
-
-
21444431821
-
Iron oxide nanoparticles for sustained delivery of anticancer agents
-
Jain TK, Morales MA, Sahoo SK, Leslie-Pelecky DL, Labhasetwar V: Iron oxide nanoparticles for sustained delivery of anticancer agents. Mol. Pharm. 2(3), 194-205 (2005).
-
(2005)
Mol. Pharm
, vol.2
, Issue.3
, pp. 194-205
-
-
Jain, T.K.1
Morales, M.A.2
Sahoo, S.K.3
Leslie-Pelecky, D.L.4
Labhasetwar, V.5
-
74
-
-
33847720312
-
In vivo imaging of siRNA delivery and silencing in tumors
-
Medarova Z, Pham W, Farrar C, Petkova V, Moore A: In vivo imaging of siRNA delivery and silencing in tumors. Nat. Med. 13(3), 372-377 (2007).
-
(2007)
Nat. Med
, vol.13
, Issue.3
, pp. 372-377
-
-
Medarova, Z.1
Pham, W.2
Farrar, C.3
Petkova, V.4
Moore, A.5
-
75
-
-
0035291243
-
Delivery of molecular and cellular medicine to solid tumors
-
Jain RK: Delivery of molecular and cellular medicine to solid tumors. Adv. Drug Deliv. Rev. 46(1-3), 149-168 (2001).
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, Issue.1-3
, pp. 149-168
-
-
Jain, R.K.1
-
76
-
-
0034993240
-
The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
-
Maeda H: The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. 41 89-207 (2001).
-
(2001)
Adv. Enzyme Regul
, vol.41
, pp. 89-207
-
-
Maeda, H.1
-
77
-
-
0041346051
-
Exploiting the hallmarks of cancer: The future conquest of breast cancer
-
Sledge GW Jr, Miller KD: Exploiting the hallmarks of cancer: the future conquest of breast cancer. Eur J. Cancer 39(12), 1668-1675 (2003).
-
(2003)
Eur J. Cancer
, vol.39
, Issue.12
, pp. 1668-1675
-
-
Sledge Jr, G.W.1
Miller, K.D.2
-
78
-
-
33846312153
-
The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform
-
Hong S, Lerouell PR, Majoros IJ et al.: The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chem. Biol. 14(1), 107-115 (2007).
-
(2007)
Chem. Biol
, vol.14
, Issue.1
, pp. 107-115
-
-
Hong, S.1
Lerouell, P.R.2
Majoros, I.J.3
-
79
-
-
33749265990
-
Multivalent effects of RGD peptides obtained by nanoparticle display
-
Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L: Multivalent effects of RGD peptides obtained by nanoparticle display. J. Med. Chem. 49(20), 6087-6093 (2006).
-
(2006)
J. Med. Chem
, vol.49
, Issue.20
, pp. 6087-6093
-
-
Montet, X.1
Funovics, M.2
Montet-Abou, K.3
Weissleder, R.4
Josephson, L.5
-
80
-
-
33748165210
-
A dual-ligand approach for enhancing targeting selectivity of therapeutic nanocarriers
-
Saul JM, Annapragada AV, Bellamkonda RV: A dual-ligand approach for enhancing targeting selectivity of therapeutic nanocarriers. J. Control Release 114(3), 277-287 (2006).
-
(2006)
J. Control Release
, vol.114
, Issue.3
, pp. 277-287
-
-
Saul, J.M.1
Annapragada, A.V.2
Bellamkonda, R.V.3
-
81
-
-
33744986992
-
Trastuzumab-modified nanoparticles: Optimisation of preparation and uptake in cancer cells
-
Steinhauser I, Spankuch B, Strebhardt K, Langer K: Trastuzumab-modified nanoparticles: optimisation of preparation and uptake in cancer cells. Biomaterials 27(28), 4975-4983 (2006).
-
(2006)
Biomaterials
, vol.27
, Issue.28
, pp. 4975-4983
-
-
Steinhauser, I.1
Spankuch, B.2
Strebhardt, K.3
Langer, K.4
-
82
-
-
0027654395
-
Antibody-magnetite nanoparticles: In vitro characterization of a potential tumor-specific contrast agent for magnetic resonance imaging
-
Tiefenauer LX, Kuhne G, Andres RY: Antibody-magnetite nanoparticles: in vitro characterization of a potential tumor-specific contrast agent for magnetic resonance imaging. Bioconjug. Chem. 4(5), 347-352 (1993).
-
(1993)
Bioconjug. Chem
, vol.4
, Issue.5
, pp. 347-352
-
-
Tiefenauer, L.X.1
Kuhne, G.2
Andres, R.Y.3
-
83
-
-
0037189380
-
Tumor regression by targeted gene delivery to the neovasculature
-
Hood JD, Bednarski M, Frausto R et al.: Tumor regression by targeted gene delivery to the neovasculature. Science 296(5577), 2404-2407 (2002).
-
(2002)
Science
, vol.296
, Issue.5577
, pp. 2404-2407
-
-
Hood, J.D.1
Bednarski, M.2
Frausto, R.3
-
84
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
Pasqualini R, Ruoslahti E: Organ targeting in vivo using phage display peptide libraries. Nature 380(6572), 364-366 (1996).
-
(1996)
Nature
, vol.380
, Issue.6572
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
85
-
-
0344185348
-
Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
-
Joyce JA, Laakkonen P. Bernasconi M et al.: Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 4(5), 393-403 (2003).
-
(2003)
Cancer Cell
, vol.4
, Issue.5
, pp. 393-403
-
-
Joyce, J.A.1
Laakkonen, P.2
Bernasconi, M.3
-
86
-
-
0030940283
-
Alpha v integrins as receptors for tumor targeting by circulating ligands
-
Pasqualini R, Koivunen E, Ruoslahti E: Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat. Biotechnol. 15(6), 542-546 (1997).
-
(1997)
Nat. Biotechnol
, vol.15
, Issue.6
, pp. 542-546
-
-
Pasqualini, R.1
Koivunen, E.2
Ruoslahti, E.3
-
87
-
-
33747441837
-
Folic acid-PEG conjugated superparamagnetic nanciparticles for targeted cellular uptake and detection by MRI
-
Sun C, Sze R, Zhang M: Folic acid-PEG conjugated superparamagnetic nanciparticles for targeted cellular uptake and detection by MRI. J. Biomed. Mater. Res. A 78(3), 550-557 (2006).
-
(2006)
J. Biomed. Mater. Res. A
, vol.78
, Issue.3
, pp. 550-557
-
-
Sun, C.1
Sze, R.2
Zhang, M.3
-
88
-
-
0037433845
-
Development of polymeric nanoparticulate drug delivery systems: Evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety
-
Kim IS, Kim SH: Development of polymeric nanoparticulate drug delivery systems: evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety. Int J. Pharm. 257(1-2), 195-203 (2003).
-
(2003)
Int J. Pharm
, vol.257
, Issue.1-2
, pp. 195-203
-
-
Kim, I.S.1
Kim, S.H.2
-
89
-
-
0005620475
-
Aptamers as therapeutic and diagnostic agents
-
Brody EN, Gold L: Aptamers as therapeutic and diagnostic agents. J. Biotechnol. 74(1), 5-13 (2000).
-
(2000)
J. Biotechnol
, vol.74
, Issue.1
, pp. 5-13
-
-
Brody, E.N.1
Gold, L.2
-
90
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington AD, Szostak JW: In vitro selection of RNA molecules that bind specific ligands. Nature 346(6287), 818-822 (1990).
-
(1990)
Nature
, vol.346
, Issue.6287
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
91
-
-
0037344674
-
Toward third-generation aptamers: Spiegelmers and their therapeutic prospects
-
Vater A, Klussmann S: Toward third-generation aptamers: Spiegelmers and their therapeutic prospects. Curr. Opin. Drug Discov. Devel. 6(2), 253-261 (2003).
-
(2003)
Curr. Opin. Drug Discov. Devel
, vol.6
, Issue.2
, pp. 253-261
-
-
Vater, A.1
Klussmann, S.2
-
92
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
Farokhzad OC, Cheng J, Teply BA et al.: Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl Acad Sci. USA 103(16), 6315-6320 (2006).
-
(2006)
Proc. Natl Acad Sci. USA
, vol.103
, Issue.16
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
-
93
-
-
33845723241
-
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
-
Bagalkot V, Farokhzad OC, Langer R, Jon S: An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. Int. Ed. Engl. 45(48), 8149-8152 (2006).
-
(2006)
Angew Chem. Int. Ed. Engl
, vol.45
, Issue.48
, pp. 8149-8152
-
-
Bagalkot, V.1
Farokhzad, O.C.2
Langer, R.3
Jon, S.4
|