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Volumn 2, Issue 5, 2007, Pages 669-680

Biodegradable, polymeric nanoparticle delivery systems for cancer therapy

Author keywords

Biodegradable polymers; Cancer therapy; Nanoparticles; Targeted

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CERAMIDE; CETUXIMAB; DENDRIMER; DEXTRAN; DNA; DOXORUBICIN; FERUMOXSIL; IRON OXIDE; MACROGOL; MESSENGER RNA; MONOCLONAL ANTIBODY; NANOPARTICLE; PACLITAXEL; PEPTIDE DERIVATIVE; PHOSPHOLIPID; PHOTOSENSITIZING AGENT; POLYAMIDOAMINE; POLYGLACTIN; POLYLACTIC ACID; POLYMER; PROTEIN DERIVATIVE; SMALL INTERFERING RNA; SUPERPARAMAGNETIC IRON OXIDE; TETANUS TOXOID; TRASTUZUMAB; UNINDEXED DRUG; VIRUS VECTOR; VIVAGEL;

EID: 37249093948     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/17435889.2.5.669     Document Type: Review
Times cited : (240)

References (93)
  • 1
    • 32944466762 scopus 로고    scopus 로고
    • Nanoparticle albumin-bound paclitaxel for metastatic breast cancer
    • Harries M, Ellis P, Harper P: Nanoparticle albumin-bound paclitaxel for metastatic breast cancer. J. Clin. Oncol. 23(31), 7768-7771 (2005).
    • (2005) J. Clin. Oncol , vol.23 , Issue.31 , pp. 7768-7771
    • Harries, M.1    Ellis, P.2    Harper, P.3
  • 2
    • 24744443165 scopus 로고    scopus 로고
    • Nanotechnology blooms, at last (Review)
    • Gordon EM, Hall FL: Nanotechnology blooms, at last (Review). Oncol. Rep. 13(6), 1003-7 (2005).
    • (2005) Oncol. Rep , vol.13 , Issue.6 , pp. 1003-1007
    • Gordon, E.M.1    Hall, F.L.2
  • 3
    • 34447523146 scopus 로고    scopus 로고
    • Pathotropic nanoparticles for cancer gene therapy Rexin-G IV: Three-year clinical experience
    • Gordon EM, Lopez FF, Cornelio GH et al.: Pathotropic nanoparticles for cancer gene therapy Rexin-G IV: three-year clinical experience. Int. J. Oncol. 29(5), 1053-1064 (2006).
    • (2006) Int. J. Oncol , vol.29 , Issue.5 , pp. 1053-1064
    • Gordon, E.M.1    Lopez, F.F.2    Cornelio, G.H.3
  • 4
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Jain RA: The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21(23), 2475-2490 (2000).
    • (2000) Biomaterials , vol.21 , Issue.23 , pp. 2475-2490
    • Jain, R.A.1
  • 5
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive MS, Anderson JM: Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Deliv. Rev. 28(1), 5-24 (1997).
    • (1997) Adv. Drug Deliv. Rev , vol.28 , Issue.1 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 6
    • 0035816535 scopus 로고    scopus 로고
    • Drug delivery. Drugs on target
    • Langer R: Drug delivery. Drugs on target. Science 293(5527), 58-59 (2001).
    • (2001) Science , vol.293 , Issue.5527 , pp. 58-59
    • Langer, R.1
  • 7
    • 33750503424 scopus 로고    scopus 로고
    • Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
    • Cheng J, Teply BA, Sherift I et a.: Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 28(5), 869-876 (2007).
    • (2007) Biomaterials , vol.28 , Issue.5 , pp. 869-876
    • Cheng, J.1    Teply, B.A.2    Sherift, I.3    et a4
  • 8
    • 0031469673 scopus 로고    scopus 로고
    • The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent
    • Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon GL: The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm. Res. 14 (11), 1568-1573 (1997).
    • (1997) Pharm. Res , vol.14 , Issue.11 , pp. 1568-1573
    • Desai, M.P.1    Labhasetwar, V.2    Walter, E.3    Levy, R.J.4    Amidon, G.L.5
  • 9
    • 7444223607 scopus 로고    scopus 로고
    • Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells
    • Farokhzad OC, Jon S, Khademhosseini A et al.: Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 64(21), 7668-7672 (2004).
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7668-7672
    • Farokhzad, O.C.1    Jon, S.2    Khademhosseini, A.3
  • 10
    • 0030471901 scopus 로고    scopus 로고
    • Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
    • Desai MP, Labhasetwar V, Amidon GL, Levy RJ: Gastrointestinal uptake of biodegradable microparticles: effect of particle size. Pharm. Res. 13(12), 1838-1845 (1996).
    • (1996) Pharm. Res , vol.13 , Issue.12 , pp. 1838-1845
    • Desai, M.P.1    Labhasetwar, V.2    Amidon, G.L.3    Levy, R.J.4
  • 11
    • 0035045942 scopus 로고    scopus 로고
    • Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups
    • Moghimi SM, Hunter AC: Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups. Pharm. Res. 18(1), 1-8 (2001).
    • (2001) Pharm. Res , vol.18 , Issue.1 , pp. 1-8
    • Moghimi, S.M.1    Hunter, A.C.2
  • 12
    • 0141927263 scopus 로고    scopus 로고
    • Stealth liposomes and long circulating nanoparticies: Critical issues in pharmacokinetics, opsonization and protein-binding properties
    • Moghimi SM, Szebeni J: Stealth liposomes and long circulating nanoparticies: critical issues in pharmacokinetics, opsonization and protein-binding properties. Prog. Lipid Res. 42(6), 463-478 (2003).
    • (2003) Prog. Lipid Res , vol.42 , Issue.6 , pp. 463-478
    • Moghimi, S.M.1    Szebeni, J.2
  • 13
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • Gref R, Minamitake Y, Peracchia MT et al.: Biodegradable long-circulating polymeric nanospheres. Science 263(5153), 1600-1603 (1994).
    • (1994) Science , vol.263 , Issue.5153 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 14
    • 0002407268 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery
    • Labhasetwar V: Nanoparticles for drug delivery. Pharm. News 4 28-31 (1997).
    • (1997) Pharm. News , vol.4 , pp. 28-31
    • Labhasetwar, V.1
  • 15
    • 0032767088 scopus 로고    scopus 로고
    • Biodegradable nanoparticles containing doxorubicin-PLGA conjugate for sustained release
    • Yoo HS, Oh JE, Lee KH, Park TG: Biodegradable nanoparticles containing doxorubicin-PLGA conjugate for sustained release. Pharm. Res. 16(7), 1114-1118 (1999).
    • (1999) Pharm. Res , vol.16 , Issue.7 , pp. 1114-1118
    • Yoo, H.S.1    Oh, J.E.2    Lee, K.H.3    Park, T.G.4
  • 16
    • 1842638560 scopus 로고    scopus 로고
    • Folate receptor targeted biodegradable polymeric doxorubicin micelles
    • Yoo HS, Park TG: Folate receptor targeted biodegradable polymeric doxorubicin micelles. J. Control Release 96(2), 273-283 (2004).
    • (2004) J. Control Release , vol.96 , Issue.2 , pp. 273-283
    • Yoo, H.S.1    Park, T.G.2
  • 17
    • 0037130252 scopus 로고    scopus 로고
    • Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages
    • Yoo HS, Lee EA, Park TG: Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J. Control Release 82 (1), 17-27 (2002).
    • (2002) J. Control Release , vol.82 , Issue.1 , pp. 17-27
    • Yoo, H.S.1    Lee, E.A.2    Park, T.G.3
  • 18
    • 0344063545 scopus 로고    scopus 로고
    • Polyacetal-doxorubicin conjugates designed for pH-dependent degradation
    • Tomlinson R, Heller J, Brocchini S, Duncan R: Polyacetal-doxorubicin conjugates designed for pH-dependent degradation. Bioconjug. Chem. 14(6), 1096-1106 (2003).
    • (2003) Bioconjug. Chem , vol.14 , Issue.6 , pp. 1096-1106
    • Tomlinson, R.1    Heller, J.2    Brocchini, S.3    Duncan, R.4
  • 19
    • 0037080616 scopus 로고    scopus 로고
    • Pendant chain functionalized polyacetals that display pH-dependent degradation: A platform for the development of novel polymer therapeutics
    • Tomlinson R, Klee M, Garrett S et al.: Pendant chain functionalized polyacetals that display pH-dependent degradation: a platform for the development of novel polymer therapeutics. Macromolecules 35 473-480 (2002).
    • (2002) Macromolecules , vol.35 , pp. 473-480
    • Tomlinson, R.1    Klee, M.2    Garrett, S.3
  • 20
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • Langer R: Drug delivery and targeting. Natuir 392(6679 Suppl), 5-10 (1998).
    • (1998) Natuir , vol.392 , Issue.6679 SUPPL. , pp. 5-10
    • Langer, R.1
  • 21
    • 0141765877 scopus 로고    scopus 로고
    • Small-scale systems for in vivo drug delivery
    • LaVan DA, McGuire T, Langer R: Small-scale systems for in vivo drug delivery. Nat. Biotechnol. 21(10), 1184-1191 (2003).
    • (2003) Nat. Biotechnol , vol.21 , Issue.10 , pp. 1184-1191
    • LaVan, D.A.1    McGuire, T.2    Langer, R.3
  • 23
    • 33750059489 scopus 로고    scopus 로고
    • Chitosan nanocapsules as carriers for oral peptide delivery: Effect of chitosan molecular weight and type of salt on the in vitro behaviour and in vivo effectiveness
    • Prego C, Torres D, Alonso MJ: Chitosan nanocapsules as carriers for oral peptide delivery: effect of chitosan molecular weight and type of salt on the in vitro behaviour and in vivo effectiveness. J. Nanosci. Nanotechnol. 6(9-10), 2921-2928 (2006).
    • (2006) J. Nanosci. Nanotechnol , vol.6 , Issue.9-10 , pp. 2921-2928
    • Prego, C.1    Torres, D.2    Alonso, M.J.3
  • 24
    • 33847175513 scopus 로고    scopus 로고
    • Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells
    • Solbrig CM, Saucier-Sawyer JK, Cody V, Saltzman WM, Hanlon DJ: Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells. Mol. Pbarm. 4(1), 47-57 (2007).
    • (2007) Mol. Pbarm , vol.4 , Issue.1 , pp. 47-57
    • Solbrig, C.M.1    Saucier-Sawyer, J.K.2    Cody, V.3    Saltzman, W.M.4    Hanlon, D.J.5
  • 25
    • 0034777178 scopus 로고    scopus 로고
    • Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid
    • Raghuvanshi RJ, Mistra A, Talwar GP, Levy RJ, Labhasetwar V: Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid. J. Microencapsul. 18 723-732 (2001).
    • (2001) J. Microencapsul , vol.18 , pp. 723-732
    • Raghuvanshi, R.J.1    Mistra, A.2    Talwar, G.P.3    Levy, R.J.4    Labhasetwar, V.5
  • 26
    • 33846139668 scopus 로고    scopus 로고
    • Nanoparticles for two-photon photodynamic therapy in living cells
    • Gao D, Agayan RR, Xu H, Philbert MA, Kopelman R: Nanoparticles for two-photon photodynamic therapy in living cells. Nano Lett. 6(11), 2383-2836 (2006).
    • (2006) Nano Lett , vol.6 , Issue.11 , pp. 2383-2836
    • Gao, D.1    Agayan, R.R.2    Xu, H.3    Philbert, M.A.4    Kopelman, R.5
  • 27
    • 30644466989 scopus 로고    scopus 로고
    • Polymeric nanoparticle preparation that eradicates tumors
    • McCarthy JR, Perez JM, Bruckner C, Weissleder R: Polymeric nanoparticle preparation that eradicates tumors. Nano. Lett. 5(12), 2552-2556 (2005).
    • (2005) Nano. Lett , vol.5 , Issue.12 , pp. 2552-2556
    • McCarthy, J.R.1    Perez, J.M.2    Bruckner, C.3    Weissleder, R.4
  • 28
    • 84950232819 scopus 로고
    • Polymeric delivery systems for controlled drug release
    • Langer R: Polymeric delivery systems for controlled drug release. Chem. Eng. Commun. 6 15-48 (1980).
    • (1980) Chem. Eng. Commun , vol.6 , pp. 15-48
    • Langer, R.1
  • 29
    • 0035844746 scopus 로고    scopus 로고
    • Mathematical modeling of bioerudible, polymeric drug delivery systems
    • Stepmann J, Gopferich A: Mathematical modeling of bioerudible, polymeric drug delivery systems. Adv. Drug Deliv. Rev. 48(2-3), 229-247 (2001).
    • (2001) Adv. Drug Deliv. Rev , vol.48 , Issue.2-3 , pp. 229-247
    • Stepmann, J.1    Gopferich, A.2
  • 30
    • 27944508780 scopus 로고    scopus 로고
    • Polyketal nanoparticles: A new pH-sensitive biodegradable drug delivery vehicle
    • Heffernan MJ, Murthy N: Polyketal nanoparticles: a new pH-sensitive biodegradable drug delivery vehicle. Bioconjug. Chem. 16(6), 1340-1342 (2005).
    • (2005) Bioconjug. Chem , vol.16 , Issue.6 , pp. 1340-1342
    • Heffernan, M.J.1    Murthy, N.2
  • 31
    • 33846199257 scopus 로고    scopus 로고
    • Targeted and intracellular delivery of paclitaxel using multi-functional polymeric micelles
    • Seow WY, Xue JM, Yang YY: Targeted and intracellular delivery of paclitaxel using multi-functional polymeric micelles. Biomaterials 28(9), 1730-1840 (2007).
    • (2007) Biomaterials , vol.28 , Issue.9 , pp. 1730-1840
    • Seow, W.Y.1    Xue, J.M.2    Yang, Y.Y.3
  • 32
    • 27144542045 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs. 1. In vitro evaluations
    • Shenoy D, Little S, Langer R, Amiji M: Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs. 1. In vitro evaluations. Mol. Pharm. 2(5), 357-366 (2005).
    • (2005) Mol. Pharm , vol.2 , Issue.5 , pp. 357-366
    • Shenoy, D.1    Little, S.2    Langer, R.3    Amiji, M.4
  • 33
  • 34
    • 33748946595 scopus 로고    scopus 로고
    • Hyperthermia-induced antitumor activity of thermosensitive polymer modified temperature-sensitive liposomes
    • Han HD, Choi MS, Hwang T et al.: Hyperthermia-induced antitumor activity of thermosensitive polymer modified temperature-sensitive liposomes. J. Pharm. Sci. 95(9), 1909-1917 (2006).
    • (2006) J. Pharm. Sci , vol.95 , Issue.9 , pp. 1909-1917
    • Han, H.D.1    Choi, M.S.2    Hwang, T.3
  • 35
    • 33745622165 scopus 로고    scopus 로고
    • Temperature-sensitive pluronic/ poly(ethylenimine) nanocapsules for thermally triggered disruption of intracellular endosomal compartment
    • Choi SH, Lee SH, Park TG: Temperature-sensitive pluronic/ poly(ethylenimine) nanocapsules for thermally triggered disruption of intracellular endosomal compartment. Biomacromolecules 7 (6), 1864-1870 (2006).
    • (2006) Biomacromolecules , vol.7 , Issue.6 , pp. 1864-1870
    • Choi, S.H.1    Lee, S.H.2    Park, T.G.3
  • 36
    • 23144456813 scopus 로고    scopus 로고
    • Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
    • Sengupta S, Eavarone D, Capila I et al.: Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature 436(7050), 568-572 (2005).
    • (2005) Nature , vol.436 , Issue.7050 , pp. 568-572
    • Sengupta, S.1    Eavarone, D.2    Capila, I.3
  • 37
    • 34250303805 scopus 로고    scopus 로고
    • Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer
    • van Vlerken LE, Duan Z, Seiden MV, Amiji MM: Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer. Cancer Res. 67(10), 4843-4850 (2007).
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4843-4850
    • van Vlerken, L.E.1    Duan, Z.2    Seiden, M.V.3    Amiji, M.M.4
  • 38
    • 33645403885 scopus 로고    scopus 로고
    • Cellpermeable and biocompatible polymeric nanoparticles for apoptosis imaging
    • Kim K, Lee M, Park H et al.: Cellpermeable and biocompatible polymeric nanoparticles for apoptosis imaging. J. Am. Chem. Soc. 128(11), 3490-3491 (2006).
    • (2006) J. Am. Chem. Soc , vol.128 , Issue.11 , pp. 3490-3491
    • Kim, K.1    Lee, M.2    Park, H.3
  • 39
    • 33746771019 scopus 로고    scopus 로고
    • Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas
    • Montet X, Weissleder R, Josephson L: Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas. Bioconjug. Chem. 17(4), 905-911 (2006).
    • (2006) Bioconjug. Chem , vol.17 , Issue.4 , pp. 905-911
    • Montet, X.1    Weissleder, R.2    Josephson, L.3
  • 40
    • 33846160552 scopus 로고    scopus 로고
    • Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
    • Nasongkla N, Bey E, Ren J et al.: Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. Nano. Lett. 6(11), 2427-2430 (2006).
    • (2006) Nano. Lett , vol.6 , Issue.11 , pp. 2427-2430
    • Nasongkla, N.1    Bey, E.2    Ren, J.3
  • 41
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W et al.: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411(6836), 494-498 (2001).
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 42
    • 0347365764 scopus 로고    scopus 로고
    • An overview of current delivery systems in cancer gene therapy
    • El-Aneed A: An overview of current delivery systems in cancer gene therapy. J. Control. Release 94(1), 1-14 (2004).
    • (2004) J. Control. Release , vol.94 , Issue.1 , pp. 1-14
    • El-Aneed, A.1
  • 43
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay MA, Glorioso JC, Naldini L: Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat. Med. 7(1), 33-40 (2001).
    • (2001) Nat. Med , vol.7 , Issue.1 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 44
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan T, Kopecek J, Kissel T: Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv. Drug Deliv. Rev. 54(5), 715-758 (2002).
    • (2002) Adv. Drug Deliv. Rev , vol.54 , Issue.5 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 45
    • 14044272234 scopus 로고    scopus 로고
    • Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters)
    • Anderson DG, Akinc A, Hossain N, Langer R: Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters). Mol. Ther. 11(3), 426-434 (2005).
    • (2005) Mol. Ther , vol.11 , Issue.3 , pp. 426-434
    • Anderson, D.G.1    Akinc, A.2    Hossain, N.3    Langer, R.4
  • 46
    • 8644275490 scopus 로고    scopus 로고
    • A polymer library approach to suicide gene therapy for cancer
    • Anderson DG, Peng W, Akinc A et al.: A polymer library approach to suicide gene therapy for cancer. Proc. Natl Acad. Sci. USA 101(45), 16028-16033 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.45 , pp. 16028-16033
    • Anderson, D.G.1    Peng, W.2    Akinc, A.3
  • 47
    • 33749012572 scopus 로고    scopus 로고
    • Biodegradable polymeric vectors for gene delivery to human endothelial cells
    • Green JJ, Shi J, Chiu E et al.: Biodegradable polymeric vectors for gene delivery to human endothelial cells. Bioconfug. Chem. 17(5), 1162-1169 (2006).
    • (2006) Bioconfug. Chem , vol.17 , Issue.5 , pp. 1162-1169
    • Green, J.J.1    Shi, J.2    Chiu, E.3
  • 48
    • 25444482607 scopus 로고    scopus 로고
    • Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
    • Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ: Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res. 65(19), 8984-8992 (2005).
    • (2005) Cancer Res , vol.65 , Issue.19 , pp. 8984-8992
    • Hu-Lieskovan, S.1    Heidel, J.D.2    Bartlett, D.W.3    Davis, M.E.4    Triche, T.J.5
  • 49
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J et al.: Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 32(19), e149 (2004).
    • (2004) Nucleic Acids Res , vol.32 , Issue.19
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3
  • 50
    • 15444373116 scopus 로고    scopus 로고
    • RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
    • Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A: RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 12(5), 461-466 (2005).
    • (2005) Gene Ther , vol.12 , Issue.5 , pp. 461-466
    • Urban-Klein, B.1    Werth, S.2    Abuharbeid, S.3    Czubayko, F.4    Aigner, A.5
  • 51
    • 33749983751 scopus 로고    scopus 로고
    • Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
    • Wang Y, Gac, S, Ye WH, Yoon HS, Yang YY: Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat. Mater. 5(10), 791-796 (2006).
    • (2006) Nat. Mater , vol.5 , Issue.10 , pp. 791-796
    • Wang, Y.1    Gac, S.2    Ye, W.H.3    Yoon, H.S.4    Yang, Y.Y.5
  • 52
    • 0036680012 scopus 로고    scopus 로고
    • Dendritic polymer macromolecular carriers for drug delivery
    • Patri AK, Majoros IJ, Baker JR: Dendritic polymer macromolecular carriers for drug delivery. Curr. Opin. Chem. Biol. 6(4), 466-471 (2002).
    • (2002) Curr. Opin. Chem. Biol , vol.6 , Issue.4 , pp. 466-471
    • Patri, A.K.1    Majoros, I.J.2    Baker, J.R.3
  • 53
  • 54
    • 28744445460 scopus 로고    scopus 로고
    • Dendrimer biocompatibility and toxicity
    • Duncan R, Izzo L: Dendrimer biocompatibility and toxicity Adv. Drug Deliv. Rev. 57(15), 2215-2237 (2005).
    • (2005) Adv. Drug Deliv. Rev , vol.57 , Issue.15 , pp. 2215-2237
    • Duncan, R.1    Izzo, L.2
  • 55
    • 0030042315 scopus 로고    scopus 로고
    • Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers
    • Roberts JC, Bhalgat MK, Zera RT: Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst dendrimers. J. Biomed. Mater. Res. 30(1), 53-65 (1996).
    • (1996) J. Biomed. Mater. Res , vol.30 , Issue.1 , pp. 53-65
    • Roberts, J.C.1    Bhalgat, M.K.2    Zera, R.T.3
  • 56
    • 33750936437 scopus 로고    scopus 로고
    • A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
    • Lee CC, Gillies ER, Fox ME et al.: A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc. Natl Acad. Sci. USA 103(45), 16649-16654 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.45 , pp. 16649-16654
    • Lee, C.C.1    Gillies, E.R.2    Fox, M.E.3
  • 57
    • 0037161405 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
    • Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM: Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery. Macromolecules 35 3456-3462 (2002).
    • (2002) Macromolecules , vol.35 , pp. 3456-3462
    • Luo, D.1    Haverstick, K.2    Belcheva, N.3    Han, E.4    Saltzman, W.M.5
  • 58
    • 27444439072 scopus 로고    scopus 로고
    • A Family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gone delivery
    • Wood KC, Little SR, Langer R, Hammond PT. A Family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gone delivery. Angew. Chem. Int. Ed. 44, 6704-6708 (2005).
    • (2005) Angew. Chem. Int. Ed , vol.44 , pp. 6704-6708
    • Wood, K.C.1    Little, S.R.2    Langer, R.3    Hammond, P.T.4
  • 59
    • 33846456200 scopus 로고    scopus 로고
    • Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells
    • Myc A, Majoros IJ, Thomas TP, Baker JR Jr: Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. Biomacromolecules 8(1), 13-18 (2007).
    • (2007) Biomacromolecules , vol.8 , Issue.1 , pp. 13-18
    • Myc, A.1    Majoros, I.J.2    Thomas, T.P.3    Baker Jr, J.R.4
  • 60
    • 33644593095 scopus 로고    scopus 로고
    • PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, functionality
    • Majoros IJ, Myc A, Thomas T, Mehta CB, Baker JR Jr: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, functionality. Biomacromolecules 7(2), 572-579 (2006).
    • (2006) Biomacromolecules , vol.7 , Issue.2 , pp. 572-579
    • Majoros, I.J.1    Myc, A.2    Thomas, T.3    Mehta, C.B.4    Baker Jr, J.R.5
  • 61
    • 23944434447 scopus 로고    scopus 로고
    • Dendrimers as drugs: Discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention
    • McCarthy TD, Karetias P, Henderson SA et al.: Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention. Mol. Pharm. 2(4), 312-318 (2005).
    • (2005) Mol. Pharm , vol.2 , Issue.4 , pp. 312-318
    • McCarthy, T.D.1    Karetias, P.2    Henderson, S.A.3
  • 62
    • 33846393538 scopus 로고    scopus 로고
    • Synthesis of biocompatible poly[2-(methacryloyloxy)ethylphosphorylcholine]- coated magnetite nanoparticles
    • Yuan JJ, Armes SP, Takabayashi Y et al.: Synthesis of biocompatible poly[2-(methacryloyloxy)ethylphosphorylcholine]- coated magnetite nanoparticles. Langmuir 22(26), 10989-10993 (2006).
    • (2006) Langmuir , vol.22 , Issue.26 , pp. 10989-10993
    • Yuan, J.J.1    Armes, S.P.2    Takabayashi, Y.3
  • 63
    • 0037373410 scopus 로고    scopus 로고
    • MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles
    • Artemov D, Mori N, Okollie B, Bhujwalla ZM: MR molecular imaging of the Her-2/neu receptor in breast cancer cells using targeted iron oxide nanoparticles. Magn. Reson. Med. 49(3), 403-408 (2003).
    • (2003) Magn. Reson. Med , vol.49 , Issue.3 , pp. 403-408
    • Artemov, D.1    Mori, N.2    Okollie, B.3    Bhujwalla, Z.M.4
  • 64
    • 0035173736 scopus 로고    scopus 로고
    • Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent
    • Zhao M, Beauregard DA, Loizou L, Davletov B, Brindle KM: Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat. Med. 7(11), 1241-1244 (2001).
    • (2001) Nat. Med , vol.7 , Issue.11 , pp. 1241-1244
    • Zhao, M.1    Beauregard, D.A.2    Loizou, L.3    Davletov, B.4    Brindle, K.M.5
  • 65
    • 1642515770 scopus 로고    scopus 로고
    • Novel nanosensors for rapid analysis of telomerase activity
    • Grimm J, Perez JM, Josephson L, Weissleder R: Novel nanosensors for rapid analysis of telomerase activity. Cancer Res. 64(2), 639-643 (2004).
    • (2004) Cancer Res , vol.64 , Issue.2 , pp. 639-643
    • Grimm, J.1    Perez, J.M.2    Josephson, L.3    Weissleder, R.4
  • 66
    • 33846545130 scopus 로고    scopus 로고
    • Biomimetic amplification of nanoparticle homing to tumors
    • Simberg D, Duza T, Park JH et al.: Biomimetic amplification of nanoparticle homing to tumors. Proc. Natl Acad. Sci. USA 104(3), 932-936 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.3 , pp. 932-936
    • Simberg, D.1    Duza, T.2    Park, J.H.3
  • 67
    • 0032426610 scopus 로고    scopus 로고
    • Superparamagnetic agents in magnetic resonance imaging: Physicochemical characteristics and clinical applications. A review
    • Bonnemain B: Superparamagnetic agents in magnetic resonance imaging: physicochemical characteristics and clinical applications. A review. J Drug Target 6(3), 167-174 (1998).
    • (1998) J Drug Target , vol.6 , Issue.3 , pp. 167-174
    • Bonnemain, B.1
  • 68
    • 0027481138 scopus 로고
    • Inductive heating of ferrimagnetic particles and magnetic fluids: Physical evaluation of their potential for hyperthermia
    • Jordan A, Wust P, Fahling H et al.: Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia. Int. J. Hyperthermia 9(1), 51-68 (1993).
    • (1993) Int. J. Hyperthermia , vol.9 , Issue.1 , pp. 51-68
    • Jordan, A.1    Wust, P.2    Fahling, H.3
  • 69
    • 0036299353 scopus 로고    scopus 로고
    • Magnetically mediated hyperthermia: Current status and future directions
    • Moroz P, Jones SK, Gray BN: Magnetically mediated hyperthermia: current status and future directions. Int. J. Hyperthermia 18(4), 267-284 (2002)..
    • (2002) Int. J. Hyperthermia , vol.18 , Issue.4 , pp. 267-284
    • Moroz, P.1    Jones, S.K.2    Gray, B.N.3
  • 70
    • 11044222650 scopus 로고    scopus 로고
    • Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    • Gupta AK, Gupta M: Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26(18), 3995-4021 (2005).
    • (2005) Biomaterials , vol.26 , Issue.18 , pp. 3995-4021
    • Gupta, A.K.1    Gupta, M.2
  • 71
    • 34249858538 scopus 로고    scopus 로고
    • Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial
    • Johannsen M, Gneveckow U, Taymoorian K et al.: Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: Results of a prospective phase I trial. Int. J. Hyperthermia 23(3), 315-323 (2007).
    • (2007) Int. J. Hyperthermia , vol.23 , Issue.3 , pp. 315-323
    • Johannsen, M.1    Gneveckow, U.2    Taymoorian, K.3
  • 72
    • 33745473776 scopus 로고    scopus 로고
    • Fluorescence-modified superparamagnetic nanoparticles: Intracellular uptake and use in cellular imaging
    • Bertorelle F, Wilhelm C, Roger J et al.: Fluorescence-modified superparamagnetic nanoparticles: intracellular uptake and use in cellular imaging. Langmuir 22(12), 5385-5391 (2006).
    • (2006) Langmuir , vol.22 , Issue.12 , pp. 5385-5391
    • Bertorelle, F.1    Wilhelm, C.2    Roger, J.3
  • 74
    • 33847720312 scopus 로고    scopus 로고
    • In vivo imaging of siRNA delivery and silencing in tumors
    • Medarova Z, Pham W, Farrar C, Petkova V, Moore A: In vivo imaging of siRNA delivery and silencing in tumors. Nat. Med. 13(3), 372-377 (2007).
    • (2007) Nat. Med , vol.13 , Issue.3 , pp. 372-377
    • Medarova, Z.1    Pham, W.2    Farrar, C.3    Petkova, V.4    Moore, A.5
  • 75
    • 0035291243 scopus 로고    scopus 로고
    • Delivery of molecular and cellular medicine to solid tumors
    • Jain RK: Delivery of molecular and cellular medicine to solid tumors. Adv. Drug Deliv. Rev. 46(1-3), 149-168 (2001).
    • (2001) Adv. Drug Deliv. Rev , vol.46 , Issue.1-3 , pp. 149-168
    • Jain, R.K.1
  • 76
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • Maeda H: The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. 41 89-207 (2001).
    • (2001) Adv. Enzyme Regul , vol.41 , pp. 89-207
    • Maeda, H.1
  • 77
    • 0041346051 scopus 로고    scopus 로고
    • Exploiting the hallmarks of cancer: The future conquest of breast cancer
    • Sledge GW Jr, Miller KD: Exploiting the hallmarks of cancer: the future conquest of breast cancer. Eur J. Cancer 39(12), 1668-1675 (2003).
    • (2003) Eur J. Cancer , vol.39 , Issue.12 , pp. 1668-1675
    • Sledge Jr, G.W.1    Miller, K.D.2
  • 78
    • 33846312153 scopus 로고    scopus 로고
    • The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform
    • Hong S, Lerouell PR, Majoros IJ et al.: The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chem. Biol. 14(1), 107-115 (2007).
    • (2007) Chem. Biol , vol.14 , Issue.1 , pp. 107-115
    • Hong, S.1    Lerouell, P.R.2    Majoros, I.J.3
  • 79
  • 80
    • 33748165210 scopus 로고    scopus 로고
    • A dual-ligand approach for enhancing targeting selectivity of therapeutic nanocarriers
    • Saul JM, Annapragada AV, Bellamkonda RV: A dual-ligand approach for enhancing targeting selectivity of therapeutic nanocarriers. J. Control Release 114(3), 277-287 (2006).
    • (2006) J. Control Release , vol.114 , Issue.3 , pp. 277-287
    • Saul, J.M.1    Annapragada, A.V.2    Bellamkonda, R.V.3
  • 81
    • 33744986992 scopus 로고    scopus 로고
    • Trastuzumab-modified nanoparticles: Optimisation of preparation and uptake in cancer cells
    • Steinhauser I, Spankuch B, Strebhardt K, Langer K: Trastuzumab-modified nanoparticles: optimisation of preparation and uptake in cancer cells. Biomaterials 27(28), 4975-4983 (2006).
    • (2006) Biomaterials , vol.27 , Issue.28 , pp. 4975-4983
    • Steinhauser, I.1    Spankuch, B.2    Strebhardt, K.3    Langer, K.4
  • 82
    • 0027654395 scopus 로고
    • Antibody-magnetite nanoparticles: In vitro characterization of a potential tumor-specific contrast agent for magnetic resonance imaging
    • Tiefenauer LX, Kuhne G, Andres RY: Antibody-magnetite nanoparticles: in vitro characterization of a potential tumor-specific contrast agent for magnetic resonance imaging. Bioconjug. Chem. 4(5), 347-352 (1993).
    • (1993) Bioconjug. Chem , vol.4 , Issue.5 , pp. 347-352
    • Tiefenauer, L.X.1    Kuhne, G.2    Andres, R.Y.3
  • 83
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • Hood JD, Bednarski M, Frausto R et al.: Tumor regression by targeted gene delivery to the neovasculature. Science 296(5577), 2404-2407 (2002).
    • (2002) Science , vol.296 , Issue.5577 , pp. 2404-2407
    • Hood, J.D.1    Bednarski, M.2    Frausto, R.3
  • 84
    • 0029932458 scopus 로고    scopus 로고
    • Organ targeting in vivo using phage display peptide libraries
    • Pasqualini R, Ruoslahti E: Organ targeting in vivo using phage display peptide libraries. Nature 380(6572), 364-366 (1996).
    • (1996) Nature , vol.380 , Issue.6572 , pp. 364-366
    • Pasqualini, R.1    Ruoslahti, E.2
  • 85
    • 0344185348 scopus 로고    scopus 로고
    • Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
    • Joyce JA, Laakkonen P. Bernasconi M et al.: Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 4(5), 393-403 (2003).
    • (2003) Cancer Cell , vol.4 , Issue.5 , pp. 393-403
    • Joyce, J.A.1    Laakkonen, P.2    Bernasconi, M.3
  • 86
    • 0030940283 scopus 로고    scopus 로고
    • Alpha v integrins as receptors for tumor targeting by circulating ligands
    • Pasqualini R, Koivunen E, Ruoslahti E: Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat. Biotechnol. 15(6), 542-546 (1997).
    • (1997) Nat. Biotechnol , vol.15 , Issue.6 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 87
    • 33747441837 scopus 로고    scopus 로고
    • Folic acid-PEG conjugated superparamagnetic nanciparticles for targeted cellular uptake and detection by MRI
    • Sun C, Sze R, Zhang M: Folic acid-PEG conjugated superparamagnetic nanciparticles for targeted cellular uptake and detection by MRI. J. Biomed. Mater. Res. A 78(3), 550-557 (2006).
    • (2006) J. Biomed. Mater. Res. A , vol.78 , Issue.3 , pp. 550-557
    • Sun, C.1    Sze, R.2    Zhang, M.3
  • 88
    • 0037433845 scopus 로고    scopus 로고
    • Development of polymeric nanoparticulate drug delivery systems: Evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety
    • Kim IS, Kim SH: Development of polymeric nanoparticulate drug delivery systems: evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety. Int J. Pharm. 257(1-2), 195-203 (2003).
    • (2003) Int J. Pharm , vol.257 , Issue.1-2 , pp. 195-203
    • Kim, I.S.1    Kim, S.H.2
  • 89
    • 0005620475 scopus 로고    scopus 로고
    • Aptamers as therapeutic and diagnostic agents
    • Brody EN, Gold L: Aptamers as therapeutic and diagnostic agents. J. Biotechnol. 74(1), 5-13 (2000).
    • (2000) J. Biotechnol , vol.74 , Issue.1 , pp. 5-13
    • Brody, E.N.1    Gold, L.2
  • 90
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW: In vitro selection of RNA molecules that bind specific ligands. Nature 346(6287), 818-822 (1990).
    • (1990) Nature , vol.346 , Issue.6287 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 91
    • 0037344674 scopus 로고    scopus 로고
    • Toward third-generation aptamers: Spiegelmers and their therapeutic prospects
    • Vater A, Klussmann S: Toward third-generation aptamers: Spiegelmers and their therapeutic prospects. Curr. Opin. Drug Discov. Devel. 6(2), 253-261 (2003).
    • (2003) Curr. Opin. Drug Discov. Devel , vol.6 , Issue.2 , pp. 253-261
    • Vater, A.1    Klussmann, S.2
  • 92
    • 33646582037 scopus 로고    scopus 로고
    • Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
    • Farokhzad OC, Cheng J, Teply BA et al.: Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl Acad Sci. USA 103(16), 6315-6320 (2006).
    • (2006) Proc. Natl Acad Sci. USA , vol.103 , Issue.16 , pp. 6315-6320
    • Farokhzad, O.C.1    Cheng, J.2    Teply, B.A.3
  • 93
    • 33845723241 scopus 로고    scopus 로고
    • An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
    • Bagalkot V, Farokhzad OC, Langer R, Jon S: An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. Int. Ed. Engl. 45(48), 8149-8152 (2006).
    • (2006) Angew Chem. Int. Ed. Engl , vol.45 , Issue.48 , pp. 8149-8152
    • Bagalkot, V.1    Farokhzad, O.C.2    Langer, R.3    Jon, S.4


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