Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

Gene Therapy

Volumn 11, Issue 19, 2004, Pages 1441-1452

  Koping Hoggard M ^a   Varum K M ^b   Issa, M ^a   Danielsen, S ^b   Christensen, B E ^b   Stokke, B T ^b   Artursson, P ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Chitosan; Nonviral gene delivery; Nonviral gene therapy; Plasmid DNA; Polyethylenimine

Indexed keywords

CHITOSAN; HEPARIN; LUCIFERASE; OLIGOMER; PLASMID DNA; POLYETHYLENEIMINE;

AREA UNDER THE CURVE; ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SOLUBILITY; VISCOSITY;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CHITOSAN; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LUCIFERASES; LUNG; MICE; POLYETHYLENEIMINE; POLYMERS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 5444267326     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302312     Document Type: Article

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