-
1
-
-
0033593316
-
Size control in animal development
-
Conlon I, Raff M (1999) Size control in animal development. Cell 96: 235-244.
-
(1999)
Cell
, vol.96
, pp. 235-244
-
-
Conlon, I.1
Raff, M.2
-
2
-
-
34249679614
-
mTOR Complex1-S6K1 signaling: At the crossroads of obesity, diabetes and cancer
-
Dann SG, Selvaraj A, Thomas G (2007) mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer. Trends Mol Med 13: 252-259.
-
(2007)
Trends Mol Med
, vol.13
, pp. 252-259
-
-
Dann, S.G.1
Selvaraj, A.2
Thomas, G.3
-
3
-
-
33845340819
-
How flies get their size: Genetics meets physiology
-
Edgar BA (2006) How flies get their size: genetics meets physiology. Nat Rev Genet 7: 907-916.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 907-916
-
-
Edgar, B.A.1
-
4
-
-
0035940680
-
Insulin signaling: Lessons from the Drosophila tuberous sclerosis complex, a tumor suppressor
-
Montagne J, Radimerski T, Thomas G (2001) Insulin signaling: lessons from the Drosophila tuberous sclerosis complex, a tumor suppressor. Sci STKE 2001: PE36.
-
(2001)
Sci STKE
-
-
Montagne, J.1
Radimerski, T.2
Thomas, G.3
-
5
-
-
0034982971
-
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
-
Gao X, Pan D (2001) TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev 15: 1383-1392.
-
(2001)
Genes Dev
, vol.15
, pp. 1383-1392
-
-
Gao, X.1
Pan, D.2
-
6
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter CJ, Huang H, Xu T (2001) Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105: 357-368.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
7
-
-
0035805180
-
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
-
Tapon N, Ito N, Dickson BJ, Treisman JE, Hariharan IK (2001) The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105: 345-355.
-
(2001)
Cell
, vol.105
, pp. 345-355
-
-
Tapon, N.1
Ito, N.2
Dickson, B.J.3
Treisman, J.E.4
Hariharan, I.K.5
-
8
-
-
0038643484
-
Rheb promotes cell growth as a component of the insulin/TOR signalling network
-
Saucedo LJ, Gao X, Chiarelli DA, Li L, Pan D, et al. (2003) Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat Cell Biol 5: 566-571.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 566-571
-
-
Saucedo, L.J.1
Gao, X.2
Chiarelli, D.A.3
Li, L.4
Pan, D.5
-
9
-
-
0038304516
-
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
-
Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, et al. (2003) Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat Cell Biol 5: 559-565.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 559-565
-
-
Stocker, H.1
Radimerski, T.2
Schindelholz, B.3
Wittwer, F.4
Belawat, P.5
-
10
-
-
0038141979
-
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
-
Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, et al. (2003) Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nat Cell Biol 5: 578-581.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 578-581
-
-
Zhang, Y.1
Gao, X.2
Saucedo, L.J.3
Ru, B.4
Edgar, B.A.5
-
11
-
-
18044381192
-
Rheb binds and regulates the mTOR kinase
-
Long X, Lin Y, Ortiz-Vega S, Yonezawa K, Avruch J (2005) Rheb binds and regulates the mTOR kinase. Curr Biol 15: 702-713.
-
(2005)
Curr Biol
, vol.15
, pp. 702-713
-
-
Long, X.1
Lin, Y.2
Ortiz-Vega, S.3
Yonezawa, K.4
Avruch, J.5
-
12
-
-
0035916357
-
An evolutionarily conserved function of the Drosophila insulin receptor and insulinlike peptides in growth control
-
Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, et al. (2001) An evolutionarily conserved function of the Drosophila insulin receptor and insulinlike peptides in growth control. Curr Biol 11: 213-221.
-
(2001)
Curr Biol
, vol.11
, pp. 213-221
-
-
Brogiolo, W.1
Stocker, H.2
Ikeya, T.3
Rintelen, F.4
Fernandez, R.5
-
13
-
-
0034312279
-
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
-
Oldham S, Montagne J, Radimerski T, Thomas G, Hafen E (2000) Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes Dev 14: 2689-2694.
-
(2000)
Genes Dev
, vol.14
, pp. 2689-2694
-
-
Oldham, S.1
Montagne, J.2
Radimerski, T.3
Thomas, G.4
Hafen, E.5
-
14
-
-
0141733277
-
A nutrient sensor mechanism controls Drosophila growth
-
Colombani J, Raisin S, Pantalacci S, Radimerski T, Montagne J, et al. (2003) A nutrient sensor mechanism controls Drosophila growth. Cell 114: 739-749.
-
(2003)
Cell
, vol.114
, pp. 739-749
-
-
Colombani, J.1
Raisin, S.2
Pantalacci, S.3
Radimerski, T.4
Montagne, J.5
-
15
-
-
0037108151
-
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
-
Radimerski T, Montagne J, Hemmings-Mieszczak M, Thomas G (2002) Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev 16: 2627-2632.
-
(2002)
Genes Dev
, vol.16
, pp. 2627-2632
-
-
Radimerski, T.1
Montagne, J.2
Hemmings-Mieszczak, M.3
Thomas, G.4
-
16
-
-
21244456553
-
Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency
-
Long X, Ortiz-Vega S, Lin Y, Avruch J (2005) Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency. J Biol Chem 280: 23433-23436.
-
(2005)
J Biol Chem
, vol.280
, pp. 23433-23436
-
-
Long, X.1
Ortiz-Vega, S.2
Lin, Y.3
Avruch, J.4
-
17
-
-
0036119219
-
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1
-
Radimerski T, Montagne J, Rintelen F, Stocker H, van der Kaay J, et al. (2002) dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nat Cell Biol 4: 251-255.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 251-255
-
-
Radimerski, T.1
Montagne, J.2
Rintelen, F.3
Stocker, H.4
van der Kaay, J.5
-
18
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, et al. (1999) Drosophila S6 kinase: a regulator of cell size. Science 285: 2126-2129.
-
(1999)
Science
, vol.285
, pp. 2126-2129
-
-
Montagne, J.1
Stewart, M.J.2
Stocker, H.3
Hafen, E.4
Kozma, S.C.5
-
19
-
-
0036741749
-
Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth
-
Barcelo H, Stewart MJ (2002) Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth. Genesis 34: 83-85.
-
(2002)
Genesis
, vol.34
, pp. 83-85
-
-
Barcelo, H.1
Stewart, M.J.2
-
20
-
-
0034700456
-
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1- deficient mice
-
Pende M, Kozma SC, Jaquet M, Oorschot V, Burcelin R, et al. (2000) Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1- deficient mice. Nature 408: 994-997.
-
(2000)
Nature
, vol.408
, pp. 994-997
-
-
Pende, M.1
Kozma, S.C.2
Jaquet, M.3
Oorschot, V.4
Burcelin, R.5
-
21
-
-
0031860687
-
Environmental control of the cell cycle in Drosophila: Nutrition activates mitotic and endoreplicative cells by distinct mechanisms
-
Britton JS, Edgar BA (1998) Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Development 125: 2149-2158.
-
(1998)
Development
, vol.125
, pp. 2149-2158
-
-
Britton, J.S.1
Edgar, B.A.2
-
22
-
-
0017287464
-
Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila
-
Garcia-Bellido A, Ripoll P, Morata G (1976) Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila. Dev Biol 48: 132-147.
-
(1976)
Dev Biol
, vol.48
, pp. 132-147
-
-
Garcia-Bellido, A.1
Ripoll, P.2
Morata, G.3
-
23
-
-
71649107200
-
A Drosophila insulin-like peptide promotes growth during nonfeeding states
-
Slaidina M, Delanoue R, Gronke S, Partridge L, Leopold P (2009) A Drosophila insulin-like peptide promotes growth during nonfeeding states. Dev Cell 17: 874-884.
-
(2009)
Dev Cell
, vol.17
, pp. 874-884
-
-
Slaidina, M.1
Delanoue, R.2
Gronke, S.3
Partridge, L.4
Leopold, P.5
-
25
-
-
0035040496
-
Steroid regulation of autophagic programmed cell death during development
-
Lee CY, Baehrecke EH (2001) Steroid regulation of autophagic programmed cell death during development. Development 128: 1443-1455.
-
(2001)
Development
, vol.128
, pp. 1443-1455
-
-
Lee, C.Y.1
Baehrecke, E.H.2
-
26
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ, Emr SD (2000) Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
27
-
-
4344563878
-
Role and regulation of starvationinduced autophagy in the Drosophila fat body
-
Scott RC, Schuldiner O, Neufeld TP (2004) Role and regulation of starvationinduced autophagy in the Drosophila fat body. Dev Cell 7: 167-178.
-
(2004)
Dev Cell
, vol.7
, pp. 167-178
-
-
Scott, R.C.1
Schuldiner, O.2
Neufeld, T.P.3
-
28
-
-
0029294746
-
Multiple phosphorylation of ribosomal protein S6 and specific protein synthesis are required for prothoracicotropic hormonestimulated ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta
-
Song Q, Gilbert LI (1995) Multiple phosphorylation of ribosomal protein S6 and specific protein synthesis are required for prothoracicotropic hormonestimulated ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta. Insect Biochem Mol Biol 25: 591-602.
-
(1995)
Insect Biochem Mol Biol
, vol.25
, pp. 591-602
-
-
Song, Q.1
Gilbert, L.I.2
-
29
-
-
36549022180
-
Prothoracicotropic hormone regulates developmental timing and body size in Drosophila
-
McBrayer Z, Ono H, Shimell M, Parvy JP, Beckstead RB, et al. (2007) Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev Cell 13: 857-871.
-
(2007)
Dev Cell
, vol.13
, pp. 857-871
-
-
McBrayer, Z.1
Ono, H.2
Shimell, M.3
Parvy, J.P.4
Beckstead, R.B.5
-
30
-
-
27144522538
-
Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release
-
Caldwell PE, Walkiewicz M, Stern M (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr Biol 15: 1785-1795.
-
(2005)
Curr Biol
, vol.15
, pp. 1785-1795
-
-
Caldwell, P.E.1
Walkiewicz, M.2
Stern, M.3
-
31
-
-
27144524370
-
Antagonistic actions of ecdysone and insulins determine final size in Drosophila
-
Colombani J, Bianchini L, Layalle S, Pondeville E, Dauphin-Villemant C, et al. (2005) Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 310: 667-670.
-
(2005)
Science
, vol.310
, pp. 667-670
-
-
Colombani, J.1
Bianchini, L.2
Layalle, S.3
Pondeville, E.4
Dauphin-Villemant, C.5
-
32
-
-
11844257686
-
Ecdysteroid control of metamorphosis in the differentiating adult leg structures of Drosophila melanogaster
-
Mirth C (2005) Ecdysteroid control of metamorphosis in the differentiating adult leg structures of Drosophila melanogaster. Dev Biol 278: 163-174.
-
(2005)
Dev Biol
, vol.278
, pp. 163-174
-
-
Mirth, C.1
-
33
-
-
53249094103
-
The TOR pathway couples nutrition and developmental timing in Drosophila
-
Layalle S, Arquier N, Leopold P (2008) The TOR pathway couples nutrition and developmental timing in Drosophila. Dev Cell 15: 568-577.
-
(2008)
Dev Cell
, vol.15
, pp. 568-577
-
-
Layalle, S.1
Arquier, N.2
Leopold, P.3
-
34
-
-
71649090271
-
A fat body-derived IGF-like peptide regulates postfeeding growth in Drosophila
-
Okamoto N, Yamanaka N, Yagi Y, Nishida Y, Kataoka H, et al. (2009) A fat body-derived IGF-like peptide regulates postfeeding growth in Drosophila. Dev Cell 17: 885-891.
-
(2009)
Dev Cell
, vol.17
, pp. 885-891
-
-
Okamoto, N.1
Yamanaka, N.2
Yagi, Y.3
Nishida, Y.4
Kataoka, H.5
-
35
-
-
0032518467
-
3- Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi DR, Kozlowski MT, Weng QP, Morrice N, Avruch J (1998) 3- Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr Biol 8: 69-81.
-
(1998)
Curr Biol
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
Kozlowski, M.T.2
Weng, Q.P.3
Morrice, N.4
Avruch, J.5
-
36
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, et al. (1998) Phosphorylation and activation of p70s6k by PDK1. Science 279: 707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
-
37
-
-
0029828590
-
The principal rapamycinsensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
-
Dennis PB, Pullen N, Kozma SC, Thomas G (1996) The principal rapamycinsensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol Cell Biol 16: 6242-6251.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6242-6251
-
-
Dennis, P.B.1
Pullen, N.2
Kozma, S.C.3
Thomas, G.4
-
39
-
-
10044276784
-
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
-
Reiling JH, Hafen E (2004) The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev 18: 2879-2892.
-
(2004)
Genes Dev
, vol.18
, pp. 2879-2892
-
-
Reiling, J.H.1
Hafen, E.2
-
40
-
-
33847743064
-
hvps34, an ancient player, enters a growing game: MTOR Complex1/S6K1 signaling
-
Nobukuni T, Kozma SC, Thomas G (2007) hvps34, an ancient player, enters a growing game: mTOR Complex1/S6K1 signaling. Curr Opin Cell Biol 19: 135-141.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 135-141
-
-
Nobukuni, T.1
Kozma, S.C.2
Thomas, G.3
-
41
-
-
0031000394
-
Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis
-
Lam GT, Jiang C, Thummel CS (1997) Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis. Development 124: 1757-1769.
-
(1997)
Development
, vol.124
, pp. 1757-1769
-
-
Lam, G.T.1
Jiang, C.2
Thummel, C.S.3
-
42
-
-
0030981791
-
Coordination of Drosophila metamorphosis by two ecdysone-induced nuclear receptors
-
White KP, Hurban P, Watanabe T, Hogness DS (1997) Coordination of Drosophila metamorphosis by two ecdysone-induced nuclear receptors. Science 276: 114-117.
-
(1997)
Science
, vol.276
, pp. 114-117
-
-
White, K.P.1
Hurban, P.2
Watanabe, T.3
Hogness, D.S.4
-
43
-
-
0033603208
-
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4
-
Bohni R, Riesgo-Escovar J, Oldham S, Brogiolo W, Stocker H, et al. (1999) Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97: 865-875.
-
(1999)
Cell
, vol.97
, pp. 865-875
-
-
Bohni, R.1
Riesgo-Escovar, J.2
Oldham, S.3
Brogiolo, W.4
Stocker, H.5
-
44
-
-
15944408369
-
Nuclear receptors-a perspective from Drosophila
-
King-Jones K, Thummel CS (2005) Nuclear receptors-a perspective from Drosophila. Nat Rev Genet 6: 311-323.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 311-323
-
-
King-Jones, K.1
Thummel, C.S.2
-
46
-
-
0035663143
-
Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila
-
Herzig MC, Thor S, Thomas JB, Reichert H, Hirth F (2001) Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila. Dev Genes Evol 211: 545-554.
-
(2001)
Dev Genes Evol
, vol.211
, pp. 545-554
-
-
Herzig, M.C.1
Thor, S.2
Thomas, J.B.3
Reichert, H.4
Hirth, F.5
-
47
-
-
0036753494
-
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control
-
Loewith R, Jacinto E, Wullschleger S, Lorberg A, Crespo JL, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10: 457-468.
-
(2002)
Mol Cell
, vol.10
, pp. 457-468
-
-
Loewith, R.1
Jacinto, E.2
Wullschleger, S.3
Lorberg, A.4
Crespo, J.L.5
-
48
-
-
0034976004
-
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila
-
Miron M, Verdu J, Lachance PE, Birnbaum MJ, Lasko PF, et al. (2001) The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila. Nat Cell Biol 3: 596-601.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 596-601
-
-
Miron, M.1
Verdu, J.2
Lachance, P.E.3
Birnbaum, M.J.4
Lasko, P.F.5
-
49
-
-
0032568795
-
Coordination of growth and cell division in the Drosophila wing
-
Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA (1998) Coordination of growth and cell division in the Drosophila wing. Cell 93: 1183-1193.
-
(1998)
Cell
, vol.93
, pp. 1183-1193
-
-
Neufeld, T.P.1
de la Cruz, A.F.2
Johnston, L.A.3
Edgar, B.A.4
-
51
-
-
0030694718
-
DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis
-
Carney GE, Wade AA, Sapra R, Goldstein ES, Bender M (1997) DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis. Proc Natl Acad Sci U S A 94: 12024-12029.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12024-12029
-
-
Carney, G.E.1
Wade, A.A.2
Sapra, R.3
Goldstein, E.S.4
Bender, M.5
-
52
-
-
0027267041
-
Analysis of genetic mosaics in developing and adult Drosophila tissues
-
Xu T, Rubin GM (1993) Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117: 1223-1237.
-
(1993)
Development
, vol.117
, pp. 1223-1237
-
-
Xu, T.1
Rubin, G.M.2
-
53
-
-
0034053414
-
Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
-
Newsome TP, Asling B, Dickson BJ (2000) Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127: 851-860.
-
(2000)
Development
, vol.127
, pp. 851-860
-
-
Newsome, T.P.1
Asling, B.2
Dickson, B.J.3
-
54
-
-
0034437022
-
Genetic and molecular mechanisms of cell size control
-
Montagne J (2000) Genetic and molecular mechanisms of cell size control. Mol Cell Biol Res Commun 4: 195-202.
-
(2000)
Mol Cell Biol Res Commun
, vol.4
, pp. 195-202
-
-
Montagne, J.1
-
55
-
-
0242267067
-
Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development
-
Sullivan AA, Thummel CS (2003) Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development. Mol Endocrinol 17: 2125-2137.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2125-2137
-
-
Sullivan, A.A.1
Thummel, C.S.2
-
56
-
-
38349122178
-
New players in the regulation of ecdysone biosynthesis
-
Huang X, Warren JT, Gilbert LI (2008) New players in the regulation of ecdysone biosynthesis. J Genet Genomics 35: 1-10.
-
(2008)
J Genet Genomics
, vol.35
, pp. 1-10
-
-
Huang, X.1
Warren, J.T.2
Gilbert, L.I.3
-
57
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
McKenna NJ, O'Malley BW (2002) Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108: 465-474.
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
58
-
-
0024337858
-
Determinants of target gene specificity for steroid/thyroid hormone receptors
-
Umesono K, Evans RM (1989) Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell 57: 1139-1146.
-
(1989)
Cell
, vol.57
, pp. 1139-1146
-
-
Umesono, K.1
Evans, R.M.2
-
59
-
-
0036696845
-
Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila
-
Bialecki M, Shilton A, Fichtenberg C, Segraves WA, Thummel CS (2002) Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila. Dev Cell 3: 209-220.
-
(2002)
Dev Cell
, vol.3
, pp. 209-220
-
-
Bialecki, M.1
Shilton, A.2
Fichtenberg, C.3
Segraves, W.A.4
Thummel, C.S.5
-
60
-
-
22744432559
-
The Drosophila nuclear receptor e75 contains heme and is gas responsive
-
Reinking J, Lam MM, Pardee K, Sampson HM, Liu S, et al. (2005) The Drosophila nuclear receptor e75 contains heme and is gas responsive. Cell 122: 195-207.
-
(2005)
Cell
, vol.122
, pp. 195-207
-
-
Reinking, J.1
Lam, M.M.2
Pardee, K.3
Sampson, H.M.4
Liu, S.5
-
61
-
-
0030001371
-
An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors
-
Seol W, Choi HS, Moore DD (1996) An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science 272: 1336-1339.
-
(1996)
Science
, vol.272
, pp. 1336-1339
-
-
Seol, W.1
Choi, H.S.2
Moore, D.D.3
-
62
-
-
0037224484
-
Nongenomic actions of steroid hormones
-
Losel R, Wehling M (2003) Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 4: 46-56.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 46-56
-
-
Losel, R.1
Wehling, M.2
-
63
-
-
0037067756
-
A vitamin D receptor-Ser/Thr phosphatase-p70 S6 kinase complex and modulation of its enzymatic activities by the ligand
-
Bettoun DJ, Buck DW, 2nd, Lu J, Khalifa B, Chin WW, et al. (2002) A vitamin D receptor-Ser/Thr phosphatase-p70 S6 kinase complex and modulation of its enzymatic activities by the ligand. J Biol Chem 277: 24847-24850.
-
(2002)
J Biol Chem
, vol.277
, pp. 24847-24850
-
-
Bettoun, D.J.1
Buck II, D.W.2
Lu, J.3
Khalifa, B.4
Chin, W.W.5
-
64
-
-
3042545882
-
Ligand modulates VDR-Ser/Thr protein phosphatase interaction and p70S6 kinase phosphorylation in a cell-context-dependent manner
-
Bettoun DJ, Lu J, Khalifa B, Yee Y, Chin WW, et al. (2004) Ligand modulates VDR-Ser/Thr protein phosphatase interaction and p70S6 kinase phosphorylation in a cell-context-dependent manner. J Steroid Biochem Mol Biol 89-90: 195-198.
-
(2004)
J Steroid Biochem Mol Biol 89-90
, pp. 195-198
-
-
Bettoun, D.J.1
Lu, J.2
Khalifa, B.3
Yee, Y.4
Chin, W.W.5
-
65
-
-
13544274110
-
Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells
-
Lal L, Li Y, Smith J, Sassano A, Uddin S, et al. (2005) Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells. Blood 105: 1669-1677.
-
(2005)
Blood
, vol.105
, pp. 1669-1677
-
-
Lal, L.1
Li, Y.2
Smith, J.3
Sassano, A.4
Uddin, S.5
-
66
-
-
15044364708
-
Nuclear receptors and their relevance to diseases related to lipid metabolism
-
Berkenstam A, Gustafsson JA (2005) Nuclear receptors and their relevance to diseases related to lipid metabolism. Curr Opin Pharmacol 5: 171-176.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 171-176
-
-
Berkenstam, A.1
Gustafsson, J.A.2
-
67
-
-
33750332589
-
Dynamic regulation of Drosophila nuclear receptor activity in vivo
-
Palanker L, Necakov AS, Sampson HM, Ni R, Hu C, et al. (2006) Dynamic regulation of Drosophila nuclear receptor activity in vivo. Development 133: 3549-3562.
-
(2006)
Development
, vol.133
, pp. 3549-3562
-
-
Palanker, L.1
Necakov, A.S.2
Sampson, H.M.3
Ni, R.4
Hu, C.5
-
68
-
-
34548815191
-
The orphan Rev-erb nuclear receptors: A link between metabolism, circadian rhythm and inflammation?
-
Ramakrishnan SN, Muscat GE (2006) The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation? Nucl Recept Signal 4: e009.
-
(2006)
Nucl Recept Signal
, vol.e009
, pp. 4
-
-
Ramakrishnan, S.N.1
Muscat, G.E.2
-
69
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, et al. (2004) Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 431: 200-205.
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
-
70
-
-
49649099595
-
The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: Staggerer (sg/sg) mice are resistant to diet induced obesity
-
Lau P, Fitzsimmons R, Raichur S, Wang SC, Lechtken A, et al. (2008) The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (sg/sg) mice are resistant to diet induced obesity. J Biol Chem.
-
(2008)
J Biol Chem
-
-
Lau, P.1
Fitzsimmons, R.2
Raichur, S.3
Wang, S.C.4
Lechtken, A.5
-
71
-
-
1842848068
-
X-ray structure of the hRORalpha LBD at 1.63 A: Structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha
-
Kallen JA, Schlaeppi JM, Bitsch F, Geisse S, Geiser M, et al. (2002) X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha. Structure 10: 1697-1707.
-
(2002)
Structure
, vol.10
, pp. 1697-1707
-
-
Kallen, J.A.1
Schlaeppi, J.M.2
Bitsch, F.3
Geisse, S.4
Geiser, M.5
-
72
-
-
70450212317
-
The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis
-
Horner MA, Pardee K, Liu S, King-Jones K, Lajoie G, et al. (2009) The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis. Genes Dev 23: 2711-2716.
-
(2009)
Genes Dev
, vol.23
, pp. 2711-2716
-
-
Horner, M.A.1
Pardee, K.2
Liu, S.3
King-Jones, K.4
Lajoie, G.5
-
73
-
-
0035502971
-
X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation
-
Stehlin C, Wurtz JM, Steinmetz A, Greiner E, Schule R, et al. (2001) X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. Embo J 20: 5822-5831.
-
(2001)
Embo J
, vol.20
, pp. 5822-5831
-
-
Stehlin, C.1
Wurtz, J.M.2
Steinmetz, A.3
Greiner, E.4
Schule, R.5
-
74
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1
-
Um SH, D'Alessio D, Thomas G (2006) Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab 3: 393-402.
-
(2006)
S6K1. Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
75
-
-
0033376684
-
PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development
-
Huang H, Potter CJ, Tao W, Li DM, Brogiolo W, et al. (1999) PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development 126: 5365-5372.
-
(1999)
Development
, vol.126
, pp. 5365-5372
-
-
Huang, H.1
Potter, C.J.2
Tao, W.3
Li, D.M.4
Brogiolo, W.5
-
76
-
-
0033582219
-
Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila
-
Hauck B, Gehring WJ, Walldorf U (1999) Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc Natl Acad Sci U S A 96: 564-569.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 564-569
-
-
Hauck, B.1
Gehring, W.J.2
Walldorf, U.3
-
77
-
-
0242389571
-
Shrinkage control: Regulation of insulin-mediated growth by FOXO transcription factors
-
Neufeld TP (2003) Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors. J Biol 2: 18.
-
(2003)
J Biol
, vol.2
, pp. 18
-
-
Neufeld, T.P.1
-
78
-
-
0036741799
-
Spliceactivated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in Drosophila melanogaster
-
Reichhart JM, Ligoxygakis P, Naitza S, Woerfel G, Imler JL, et al. (2002) Spliceactivated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in Drosophila melanogaster. Genesis 34: 160-164.
-
(2002)
Genesis
, vol.34
, pp. 160-164
-
-
Reichhart, J.M.1
Ligoxygakis, P.2
Naitza, S.3
Woerfel, G.4
Imler, J.L.5
-
79
-
-
11844287569
-
Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E
-
Reiling JH, Doepfner KT, Hafen E, Stocker H (2005) Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E. Curr Biol 15: 24-30.
-
(2005)
Curr Biol
, vol.15
, pp. 24-30
-
-
Reiling, J.H.1
Doepfner, K.T.2
Hafen, E.3
Stocker, H.4
-
80
-
-
0029662156
-
The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity
-
Stewart MJ, Berry CO, Zilberman F, Thomas G, Kozma SC (1996) The Drosophila p70s6k homolog exhibits conserved regulatory elements and rapamycin sensitivity. Proc Natl Acad Sci U S A 93: 10791-10796.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10791-10796
-
-
Stewart, M.J.1
Berry, C.O.2
Zilberman, F.3
Thomas, G.4
Kozma, S.C.5
|