X-ray structure of the orphan nuclear receptor RORβ ligand-binding domain in the active conformation

EMBO Journal

Volumn 20, Issue 21, 2001, Pages 5822-5831

  Stehlin, Catherine ^a   Wurtz, Jean Marie ^a   Steinmetz, Anke ^a   Greiner, Erich ^b,c   Schüle, Roland ^b   Moras, Dino ^a   Renaud, Jean Paul ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF FREIBURG   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Crystal structure; Nuclear receptor; Orphan; ROR RZR

Indexed keywords

CARBOXYL GROUP; CELL NUCLEUS RECEPTOR; FATTY ACID; RETINOIC ACID RECEPTOR; RETINOIC ACID RELATED ORPHAN RECEPTOR BETA; STEARIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN; CRYSTAL STRUCTURE; HYDROPHOBICITY; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; RETINA; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HISTONE ACETYLTRANSFERASES; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STEARIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0035502971     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.21.5822     Document Type: Article

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