New players in the regulation of ecdysone biosynthesis

Journal of Genetics and Genomics

Volumn 35, Issue 1, 2008, Pages 1-10

  Huang, Xun ^a   Warren, James T ^b   Gilbert, Lawrence I ^b  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

cholesterol; ecdysone; P450; PTTH

Indexed keywords

CHOLESTEROL; ECDYSONE;

ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CHOLESTEROL SYNTHESIS; HORMONAL REGULATION; HORMONE SYNTHESIS; METAMORPHOSIS; MOLECULAR WEIGHT; MOLTING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROIDOGENESIS; STRUCTURE ANALYSIS;

ANIMALS; BIOSYNTHETIC PATHWAYS; CHOLESTEROL; ECDYSONE; ENZYMES; SIGNAL TRANSDUCTION; STEROLS;

HEXAPODA;

EID: 38349122178     PISSN: 16738527     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1673-8527(08)60001-6     Document Type: Article

References (51)

1. Agui N., Granger N.A., Gilbert L.I., and Bollenbacher W.E. Cellular localization of the insect prothoracicotropic hormone: In vitro assay of a single neurosecretory cell. Proc. Natl. Acad. Sci. USA 76 (1979) 5694-5698
2. Altmann S.W., Davis Jr. H.R., Zhu L.J., Yao X., Hoos L.M., Tetzloff G., Iyer S.P., Maguire M., Golovko A., Zeng M., Wang L., Murgolo N., and Graziano M.P. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 303 (2004) 1201-1204
3. Asami T., Nakano T., and Fujioka S. Plant brassinosteroid hormones. Vitam. Horm. 72 (2005) 479-504
4. Beckstead R.B., and Thummel C.S. Indicted: worms caught using steroids. Cell 124 (2006) 1137-1140
5. Caldwell P.E., Walkiewicz M., and Stern M. Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr. Biol. 15 (2005) 1785-1795
6. Carstea E.D., Morris J.A., Coleman K.G., Loftus S.K., Zhang D., Cummings C., Gu J., Rosenfeld M.A., Pavan W.J., Krizman D.B., Nagle J., Polymeropoulos M.H., Sturley S.L., Ioannou Y.A., Higgins M.E., Comly M., Cooney A., Brown A., Kaneski C.R., Blanchette-Mackie E.J., Dwyer N.K., Neufeld E.B., Chang T.Y., Liscum L., Strauss III J.F., Ohno K., Zeigler M., Carmi R., Sokol J., Markie D., O'Neill R.R., van Diggelen O.P., Elleder M., Patterson M.C., Brady R.O., Vanier M.T., Pentchev P.G., and Tagle D.A. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277 (1997) 228-231
7. Chávez V.M., Marqués G., Delbecque J.P., Kobayashi K., Hollingsworth M., Burr J., Natzle J.E., and O'Connor M.B. The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels. Development 127 (2000) 4115-4126
8. Christenson L.K., and Strauss III J.F. Steroidogenic acute regulatory protein (StAR) and the intramitochondrial translocation of cholesterol. Biochim. Biophys. Acta 1529 (2000) 175-187
9. Clark A.J., and Block K. The absence of sterol synthesis in insects. J. Biol. Chem. 234 (1959) 2578-2582
10. 2+ signaling in prothoracicotropic hormone-stimulated prothoracic gland cells of Manduca sexta: evidence for mobilization and entry mechanisms. Insect Biochem. Mol. Biol. 35 (2005) 263-275
11. Fluegel M.L., Parker T.J., and Pallanck L.J. Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects. Genetics 172 (2006) 185-196
12. Goldstein J.L., DeBose-Boyd R.A., and Brown M.S. Protein sensors for membrane sterols. Cell 124 (2006) 35-46
13. Griffin L.D., Gong W., Verot L., and Mellon S.H. Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat. Med. 10 (2004) 704-711
14. Henrich V.C., Pak M.D., and Gilbert L.I. Neural factors that stimulate ecdysteroid synthesis by the larval ring gland of Drosophila melanogaster. J. Comp. Physiol. [B] 157 (1987) 543-549
15. Henrich V.C., Tucker R.L., Maroni G., and Gilbert L.I. The ecdysoneless (ecd1ts) mutation disrupts ecdysteroid synthesis autonomously in the ring gland of Drosophila melanogaster. Dev. Biol. 120 (1987) 50-55
16. Hosie A.M., Wilkins M.E., da Silva H.M., and Smart T.G. Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. Nature 444 (2006) 486-489
17. Huang X., Suyama K., Buchanan J., Zhu A.J., and Scott M.P. A Drosophila model of the Niemann-Pick type C lysosome storage disease: dnpc1a is required for molting and sterol homeostasis. Development 132 (2005) 5115-5124
18. Huang X., Warrent J.T., Buchanan J., Gilbert L.I., and Scott M.P. Drosophila Niemann-Pick Type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease. Development 134 (2007) 3733-3742
19. Ishizaki H., and Suzuki A. The brain secretory peptides that control moulting and metamorphosis of the silkmoth, Bombyx mori. Int. J. Dev. Biol. 38 (1994) 301-310
20. Jürgens G., Wieschaus E., Nüsslein-Volhard C., and Kluding H. Mutations affecting the pattern of the larval curicle in Drosophila melanogaster. II Zygotic loci on the third chromosome. Roux's Arch. Dev. Biol. 193 (1984) 282-295
21. Kappler C., Kabbouh M., Hetru C., Durst F., and Hoffmann J.A. Characterization of three hydroxylases involved in the final steps of biosynthesis of the steroid hormone ecdysone in Locusta migratoria (Insecta, Orthoptera). J. Steroid Biochem. 31 (1988) 891-898
22. Kataoka H., Nagasawa H., Isogai A., Ishizaki H., and Suzuki A. Prothoracicotropic hormone of the silkworm, Bombyx mori: amino acid sequence and dimeric structure. Agric. Biol. Chem. 55 (1991) 73-86
23. Kim A.J., Cha G.H., Kim K., Gilbert L.I., and Lee C.C. Purification and characterization of the prothoracicotropic hormone of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 94 (1997) 1130-1135
24. Kopeć S. Studies on the necessity of the brain for the inception of insect metamorphosis. Biol. Bull. 42 (1922) 323-342
25. Lan Q., and Massey R.J. Subcellular localization of the mosquito sterol carrier protein-2 and sterol carrier protein-x. J. Lipid Res. 45 (2004) 1468-1474
26. Liscum L., and Faust J.R. Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts. J. Biol. Chem. 262 (1987) 17002-17008
27. McBrayer Z., Ono H., Shimell M., Parvy J.P., Beckstead R.B., Warren J.T., Thummel C.S., Dauphin-Villemant C., Gilbert L.I., and O'Connor M.B. Prothoracicotropic hormone regulates the developmental timing and body size in Drosophila. Development Cell, 13 (2007) 857-871
28. Namiki T., Niwa R., Sakudoh T., Shirai K., Takeuchi H., and Kataoka H. Cytochrome P450 CYP307A1/Spook: a regulator for ecdysone synthesis in insects. Biochem. Biophys. Res. Commun. 337 (2005) 367-374
29. Neubueser D., Warrent J.T., Gilbert L.I., and Cohen S.M. molting defective is required for ecdysone biosynthesis. Dev. Biol. 280 (2005) 362-372
30. Niwa R., Matsuda T., Yoshiyama T., Namiki T., Mita K., Fujimoto Y., and Kataoka H. CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila. J. Biol. Chem. 279 (2004) 35942-35949
31. Nüsslein-Volhard C., Wieschaus E., and Kluding H. Mutations affecting the patern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Roux's Arch. Dev. Biol. 183 (1984) 267-282
32. Ono H., Rewitz K.F., Shinoda T., Itoyama K., Petryk A., Rybczynski R., Jarcho M., Warren J.T., Marqués G., Shimell M.J., Gilbert L.I., and O'Connor M.B. Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera. Dev. Biol. 298 (2006) 555-570
33. Parkin C.A., and Burnet B. Growth arrest of Drosophila melanogaster on erg-2 and erg-6 sterol mutant strains of Saccharomyces cerevisiae. J. Insect. Physiol. 32 (1986) 463-471
34. Parvy J.P., Blais C., Bernard F., Warren J.T., Petryk A., Gilbert L.I., O'Connor M.B., and Dauphin-Villemant C. A role for betaFTZ-F1 in regulating ecdysteroid titers during post-embryonic development in Drosophila melanogaster. Dev. Biol. 282 (2005) 84-94
35. Petryk A., Warren J.T., Marqués G., Jarcho M.P., Gilbert L.I., Kahler J., Parvy J.P., Li Y., Dauphin-Villemant C., and O'Connor M.B. Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone. Proc. Natl. Acad. Sci. USA 100 (2003) 13773-13778
36. Rewitz K.F., Rybczynski R., Warrent J.T., and Gilbert L.I. The Halloween genes code for cytochrome P450 enzymes mediating synthesis of the insect moulting hormone. Biochem. Soc. Trans. 34 (2006) 1256-1260
37. Riddiford L.M., Cherbas P., and Truman J.W. Ecdysone receptors and their biological actions. Vitam. Horm. 60 (2000) 1-73
38. Rodenburg K.W., and van der Horst D.J. Lipoprotein-mediated lipid transport in insects: analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members. Biochim. Biophys. Acta 1736 (2005) 10-29
39. Roth G.E., Gierl M.S., Vollborn L., Meise M., Lintermann R., and Korge G. The Drosophila gene Start1: a putative cholesterol transporter and key regulator of ecdysteroid synthesis. Proc. Natl. Acad. Sci. USA 101 (2004) 1601-1606
40. Rottiers V.D., Gerisch M.B., Cummins C., Nishiwaki K., Mangelsdorf D., and Antebi A. Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Dev. Cell 10 (2006) 473-482
41. Smith W.A., Gilbert L.I., and Bollenbacher W.E. Calcium-cyclic AMP interactions in prothoracicotropic hormone stimulation of ecdysone synthesis. Mol. Cell. Endocrinol. 39 (1985) 71-78
42. Song Q., and Gilbert L.I. S6 phosphorylation results from prothoracicotropic hormone stimulation of insect prothoracic glands: a role for S6 kinase. Dev. Genet. 15 (1994) 332-338
43. Stolowich N.J., Petrescu A.D., Huang H., Martin G.G., Scott A.I., and Schroeder F. Sterol carrier protein-2: structure reveals function. Cell Mol. Life Sci. 59 (2002) 193-212
44. Vedeckis W.V., Bollenbacher W.E., and Gilbert L.I. Insect prothoracic glands: a role for cyclic AMP in the stimulation of alpha-ecdysone secretion. Mol. Cell. Endocrinol. 5 (1976) 81-88
45. Voght S.P., Fluegel M.L., Andrews L.A., and Pallanck L.J. Drosophila NPC1b promotes an early step in sterol absorption from the midgut epithelium. Cell Metab. 5 (2007) 195-205
46. Warren J.T., Petryk A., Marques G., Jarcho M., Parvy J.P., Dauphin-Villemant C., O'Connor M.B., and Gilbert L.I. Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 99 (2002) 11043-11048
47. Warren J.T., Petryk A., Marqués G., Parvy J.P., Shinoda T., Itoyama K., Kobayashi J., Jarcho M., Li Y., O'Connor M.B., Dauphin-Villemant C., and Gilbert L.I. Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis. Insect Biochem. Mol. Biol. 34 (2004) 991-1010
48. Warrent J.T., Wismar J., Subrahmanyam B., and Gilbert L.I. Woc (without children) gene control of ecdysone biosynthesis in Drosophila melanogaster. Mol. Cell Endocrinol. 181 (2001) 1-14
49. Wieschaus E., Nüsslein-Volhard C., and Jürgens G. Mutations affecting the pattern of the larval curicle in Drosophila melanogaster. III Zygotic loci on the X-chromosome and fourth chromosome. Roux's Arch. Dev. Biol. 193 (1984) 296-307
50. Wismar J., Habtemichael N., Warren J.T., Dai J.D., Gilbert L.I., and Gateff E. The mutation without children(rgl) causes ecdysteroid deficiency in third-instar larvae of Drosophila melanogaster. Dev. Biol. 226 (2000) 1-17
51. Yoshiyama T., Namiki T., Mita K., Kataoka H., and Niwa R. Neverland is an evolutionally conserved Rieske-domain protein that is essential for ecdysone synthesis and insect growth. Development 133 (2006) 2565-2574