-
1
-
-
65249175080
-
Coupling endoplasmic reticulum stress to the cell death program in dopaminergic cells: effect of paraquat
-
Chinta S.J., Rane A., Poksay K.S., Bredesen D.E., Andersen J.K., Rao R.V. Coupling endoplasmic reticulum stress to the cell death program in dopaminergic cells: effect of paraquat. Neuromol. Med. 2008, 10:333-342.
-
(2008)
Neuromol. Med.
, vol.10
, pp. 333-342
-
-
Chinta, S.J.1
Rane, A.2
Poksay, K.S.3
Bredesen, D.E.4
Andersen, J.K.5
Rao, R.V.6
-
2
-
-
33846053966
-
Occupational titles as risk factors for Parkinson's disease
-
Dick S., Semple S., Dick F., Seaton A. Occupational titles as risk factors for Parkinson's disease. Occup. Med. (London) 2007, 57:50-56.
-
(2007)
Occup. Med. (London)
, vol.57
, pp. 50-56
-
-
Dick, S.1
Semple, S.2
Dick, F.3
Seaton, A.4
-
3
-
-
0025230379
-
Parkinson's disease: a case-control study of occupational and environmental risk factors
-
Hertzman C., Wiens M., Bowering D., Snow B., Calne D. Parkinson's disease: a case-control study of occupational and environmental risk factors. Am. J. Ind. Med. 1990, 17:349-355.
-
(1990)
Am. J. Ind. Med.
, vol.17
, pp. 349-355
-
-
Hertzman, C.1
Wiens, M.2
Bowering, D.3
Snow, B.4
Calne, D.5
-
4
-
-
0030878320
-
Environmental risk factors and Parkinson's disease: a case-control study in Taiwan
-
Liou H.H., Tsai M.C., Chen C.J., Jeng J.S., Chang Y.C., Chen S.Y., et al. Environmental risk factors and Parkinson's disease: a case-control study in Taiwan. Neurology 1997, 48:1583-1588.
-
(1997)
Neurology
, vol.48
, pp. 1583-1588
-
-
Liou, H.H.1
Tsai, M.C.2
Chen, C.J.3
Jeng, J.S.4
Chang, Y.C.5
Chen, S.Y.6
-
5
-
-
0038143287
-
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
-
Holtz W.A., O'Malley K.L. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J. Biol. Chem. 2003, 278:19367-19377.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19367-19377
-
-
Holtz, W.A.1
O'Malley, K.L.2
-
6
-
-
0036075892
-
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
-
McCormack A.L., Thiruchelvam M., Manning-Bog A.B., Thiffault C., Langston J.W., Cory-Slechta D.A., et al. Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol. Dis. 2002, 10:119-127.
-
(2002)
Neurobiol. Dis.
, vol.10
, pp. 119-127
-
-
McCormack, A.L.1
Thiruchelvam, M.2
Manning-Bog, A.B.3
Thiffault, C.4
Langston, J.W.5
Cory-Slechta, D.A.6
-
7
-
-
0037380982
-
Effects of L-dopa and other amino acids against paraquat-induced nigrostriatal degeneration
-
McCormack A.L., Di Monte D.A. Effects of L-dopa and other amino acids against paraquat-induced nigrostriatal degeneration. J. Neurochem. 2003, 85:82-86.
-
(2003)
J. Neurochem.
, vol.85
, pp. 82-86
-
-
McCormack, A.L.1
Di Monte, D.A.2
-
8
-
-
18844373851
-
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration
-
McCormack A.L., Atienza J.G., Johnston L.C., Andersen J.K., Vu S., Di Monte D.A. Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. J. Neurochem. 2005, 93:1030-1037.
-
(2005)
J. Neurochem.
, vol.93
, pp. 1030-1037
-
-
McCormack, A.L.1
Atienza, J.G.2
Johnston, L.C.3
Andersen, J.K.4
Vu, S.5
Di Monte, D.A.6
-
9
-
-
3543011314
-
The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway
-
Peng J., Mao X.O., Stevenson F.F., Hsu M., Andersen J.K. The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway. J. Biol. Chem. 2004, 279:32626-32632.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32626-32632
-
-
Peng, J.1
Mao, X.O.2
Stevenson, F.F.3
Hsu, M.4
Andersen, J.K.5
-
10
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu E.J., Harding H.P., Angelastro J.M., Vitolo O.V., Ron D., Greene L.A. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J. Neurosci. 2002, 22:10690-10698.
-
(2002)
J. Neurosci.
, vol.22
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
Vitolo, O.V.4
Ron, D.5
Greene, L.A.6
-
11
-
-
2442551514
-
Paraquat-induced apoptotic cell death in cerebellar granule cells
-
Gonzalez-Polo R.A., Rodriguez-Martin A., Moran J.M., Niso M., Soler G., Fuentes J.M. Paraquat-induced apoptotic cell death in cerebellar granule cells. Brain Res. 2004, 1011:170-176.
-
(2004)
Brain Res.
, vol.1011
, pp. 170-176
-
-
Gonzalez-Polo, R.A.1
Rodriguez-Martin, A.2
Moran, J.M.3
Niso, M.4
Soler, G.5
Fuentes, J.M.6
-
12
-
-
34250850177
-
Relationship between autophagy and apoptotic cell death in human neuroblastoma cells treated with paraquat: could autophagy be a "brake" in paraquat-induced apoptotic death?
-
Gonzalez-Polo R.A., Niso-Santano M., Ortiz-Ortiz M.A., Gomez-Martin A., Moran J.M., Garcia-Rubio L., et al. Relationship between autophagy and apoptotic cell death in human neuroblastoma cells treated with paraquat: could autophagy be a "brake" in paraquat-induced apoptotic death?. Autophagy 2007, 3:366-367.
-
(2007)
Autophagy
, vol.3
, pp. 366-367
-
-
Gonzalez-Polo, R.A.1
Niso-Santano, M.2
Ortiz-Ortiz, M.A.3
Gomez-Martin, A.4
Moran, J.M.5
Garcia-Rubio, L.6
-
13
-
-
34250822045
-
Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells
-
Gonzalez-Polo R.A., Niso-Santano M., Ortiz-Ortiz M.A., Gomez-Martin A., Moran J.M., Garcia-Rubio L., et al. Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells. Toxicol. Sci. 2007, 97:448-458.
-
(2007)
Toxicol. Sci.
, vol.97
, pp. 448-458
-
-
Gonzalez-Polo, R.A.1
Niso-Santano, M.2
Ortiz-Ortiz, M.A.3
Gomez-Martin, A.4
Moran, J.M.5
Garcia-Rubio, L.6
-
14
-
-
0032157954
-
Apoptosis in human lung epithelial cells: triggering by paraquat and modulation by antioxidants
-
Cappelletti G., Maggioni M.G., Maci R. Apoptosis in human lung epithelial cells: triggering by paraquat and modulation by antioxidants. Cell Biol. Int. 1998, 22:671-678.
-
(1998)
Cell Biol. Int.
, vol.22
, pp. 671-678
-
-
Cappelletti, G.1
Maggioni, M.G.2
Maci, R.3
-
15
-
-
41249098254
-
Paraquat neurotoxicity is mediated by a Bak-dependent mechanism
-
Fei Q., McCormack A.L., Di Monte D.A., Ethell D.W. Paraquat neurotoxicity is mediated by a Bak-dependent mechanism. J. Biol. Chem. 2008, 283:3357-3364.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3357-3364
-
-
Fei, Q.1
McCormack, A.L.2
Di Monte, D.A.3
Ethell, D.W.4
-
16
-
-
33745764795
-
Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death
-
Niso-Santano M., Moran J.M., Garcia-Rubio L., Gomez-Martin A., Gonzalez-Polo R.A., Soler G., et al. Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death. Toxicol. Sci. 2006, 92:507-515.
-
(2006)
Toxicol. Sci.
, vol.92
, pp. 507-515
-
-
Niso-Santano, M.1
Moran, J.M.2
Garcia-Rubio, L.3
Gomez-Martin, A.4
Gonzalez-Polo, R.A.5
Soler, G.6
-
17
-
-
34347259974
-
Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis
-
Klintworth H., Newhouse K., Li T., Choi W.S., Faigle R., Xia Z. Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. Toxicol. Sci. 2007, 97:149-162.
-
(2007)
Toxicol. Sci.
, vol.97
, pp. 149-162
-
-
Klintworth, H.1
Newhouse, K.2
Li, T.3
Choi, W.S.4
Faigle, R.5
Xia, Z.6
-
18
-
-
38949123181
-
Paraquat-induced apoptosis in human neuroblastoma SH-SY5Y cells: involvement of p53 and mitochondria
-
Yang W., Tiffany-Castiglioni E. Paraquat-induced apoptosis in human neuroblastoma SH-SY5Y cells: involvement of p53 and mitochondria. J. Toxicol. Environ. Health A 2008, 71:289-299.
-
(2008)
J. Toxicol. Environ. Health A
, vol.71
, pp. 289-299
-
-
Yang, W.1
Tiffany-Castiglioni, E.2
-
19
-
-
0033954584
-
Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
-
Alexi T., Borlongan C.V., Faull R.L., Williams C.E., Clark R.G., Gluckman P.D., et al. Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases. Prog. Neurobiol. 2000, 60:409-470.
-
(2000)
Prog. Neurobiol.
, vol.60
, pp. 409-470
-
-
Alexi, T.1
Borlongan, C.V.2
Faull, R.L.3
Williams, C.E.4
Clark, R.G.5
Gluckman, P.D.6
-
20
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994, 77:817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
21
-
-
0032890439
-
Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches
-
Behl C. Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches. Prog. Neurobiol. 1999, 57:301-323.
-
(1999)
Prog. Neurobiol.
, vol.57
, pp. 301-323
-
-
Behl, C.1
-
22
-
-
51349166119
-
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
-
Chen L., Liu L., Huang S. Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5. Free Radic. Biol. Med. 2008, 45:1035-1044.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 1035-1044
-
-
Chen, L.1
Liu, L.2
Huang, S.3
-
23
-
-
0033955608
-
Cell death mechanisms in Parkinson's disease
-
Jellinger K.A. Cell death mechanisms in Parkinson's disease. J. Neural Transm. 2000, 107:1-29.
-
(2000)
J. Neural Transm.
, vol.107
, pp. 1-29
-
-
Jellinger, K.A.1
-
24
-
-
0347948518
-
Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death
-
Ruffels J., Griffin M., Dickenson J.M. Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell death. Eur. J. Pharmacol. 2004, 483:163-173.
-
(2004)
Eur. J. Pharmacol.
, vol.483
, pp. 163-173
-
-
Ruffels, J.1
Griffin, M.2
Dickenson, J.M.3
-
25
-
-
33747047814
-
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
-
Wu D.C., Re D.B., Nagai M., Ischiropoulos H., Przedborski S. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc. Natl. Acad. Sci. USA 2006, 103:12132-12137.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12132-12137
-
-
Wu, D.C.1
Re, D.B.2
Nagai, M.3
Ischiropoulos, H.4
Przedborski, S.5
-
26
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
Zhang Y., Dawson V.L., Dawson T.M. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol. Dis. 2000, 7:240-250.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
27
-
-
0031668930
-
Programmed cell death: does it play a role in Parkinson's disease?
-
Burke R.E., Kholodilov N.G. Programmed cell death: does it play a role in Parkinson's disease?. Ann. Neurol. 1998, 44:S126-S133.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Burke, R.E.1
Kholodilov, N.G.2
-
28
-
-
0033963108
-
Apoptosis and neurologic disease
-
Honig L.S., Rosenberg R.N. Apoptosis and neurologic disease. Am. J. Med. 2000, 108:317-330.
-
(2000)
Am. J. Med.
, vol.108
, pp. 317-330
-
-
Honig, L.S.1
Rosenberg, R.N.2
-
29
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H., Nishida E., Irie K., Ten Dijke P., Saitoh M., Moriguchi T., et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997, 275:90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
-
30
-
-
0033231020
-
From receptors to stress-activated MAP kinases
-
Ichijo H. From receptors to stress-activated MAP kinases. Oncogene 1999, 18:6087-6093.
-
(1999)
Oncogene
, vol.18
, pp. 6087-6093
-
-
Ichijo, H.1
-
31
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 1998, 17:2596-2606.
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
-
32
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H., Matsuzawa A., Tobiume K., Saegusa K., Takeda K., Inoue K., et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 2002, 16:1345-1355.
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
-
33
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh H., Saitoh M., Mochida Y., Takeda K., Nakano H., Rothe M., et al. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 1998, 2:389-395.
-
(1998)
Mol. Cell
, vol.2
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
-
34
-
-
1642487129
-
Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation
-
Takeda K., Matsuzawa A., Nishitoh H., Tobiume K., Kishida S., Ninomiya-Tsuji J., et al. Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation. EMBO Rep. 2004, 5:161-166.
-
(2004)
EMBO Rep.
, vol.5
, pp. 161-166
-
-
Takeda, K.1
Matsuzawa, A.2
Nishitoh, H.3
Tobiume, K.4
Kishida, S.5
Ninomiya-Tsuji, J.6
-
35
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis R.J. Signal transduction by the JNK group of MAP kinases. Cell 2000, 103:239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
36
-
-
0037380894
-
ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death
-
Sarker K.P., Biswas K.K., Yamakuchi M., Lee K.Y., Hahiguchi T., Kracht M., et al. ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death. J. Neurochem. 2003, 85:50-61.
-
(2003)
J. Neurochem.
, vol.85
, pp. 50-61
-
-
Sarker, K.P.1
Biswas, K.K.2
Yamakuchi, M.3
Lee, K.Y.4
Hahiguchi, T.5
Kracht, M.6
-
37
-
-
0346434152
-
Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2
-
Sarker K.P., Biswas K.K., Rosales J.L., Yamaji K., Hashiguchi T., Lee K.Y., et al. Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2. J. Neurochem. 2003, 87:1345-1353.
-
(2003)
J. Neurochem.
, vol.87
, pp. 1345-1353
-
-
Sarker, K.P.1
Biswas, K.K.2
Rosales, J.L.3
Yamaji, K.4
Hashiguchi, T.5
Lee, K.Y.6
-
38
-
-
0346887088
-
Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells
-
Machino T., Hashimoto S., Maruoka S., Gon Y., Hayashi S., Mizumura K., et al. Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. Crit. Care Med. 2003, 31:2776-2781.
-
(2003)
Crit. Care Med.
, vol.31
, pp. 2776-2781
-
-
Machino, T.1
Hashimoto, S.2
Maruoka, S.3
Gon, Y.4
Hayashi, S.5
Mizumura, K.6
-
39
-
-
0037115761
-
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis
-
Saeki K., Kobayashi N., Inazawa Y., Zhang H., Nishitoh H., Ichijo H., et al. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis. Biochem. J. 2002, 368:705-720.
-
(2002)
Biochem. J.
, vol.368
, pp. 705-720
-
-
Saeki, K.1
Kobayashi, N.2
Inazawa, Y.3
Zhang, H.4
Nishitoh, H.5
Ichijo, H.6
-
40
-
-
33749048083
-
Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes
-
Van Laethem A., Nys K., Van Kelst S., Claerhout S., Ichijo H., Vandenheede J.R., et al. Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes. Free Radic. Biol. Med. 2006, 41:1361-1371.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 1361-1371
-
-
Van Laethem, A.1
Nys, K.2
Van Kelst, S.3
Claerhout, S.4
Ichijo, H.5
Vandenheede, J.R.6
-
41
-
-
40049088820
-
The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity
-
Copple I.M., Goldring C.E., Kitteringham N.R., Park B.K. The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity. Toxicology 2008, 246:24-33.
-
(2008)
Toxicology
, vol.246
, pp. 24-33
-
-
Copple, I.M.1
Goldring, C.E.2
Kitteringham, N.R.3
Park, B.K.4
-
42
-
-
27844612530
-
Nrf2 as a target for cancer chemoprevention
-
Yu X., Kensler T. Nrf2 as a target for cancer chemoprevention. Mutat. Res. 2005, 591:93-102.
-
(2005)
Mutat. Res.
, vol.591
, pp. 93-102
-
-
Yu, X.1
Kensler, T.2
-
43
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999, 13:76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
-
44
-
-
4544294365
-
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan S.B., Gordan J.D., Jin J., Harper J.W., Diehl J.A. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol. Cell. Biol. 2004, 24:8477-8486.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8477-8486
-
-
Cullinan, S.B.1
Gordan, J.D.2
Jin, J.3
Harper, J.W.4
Diehl, J.A.5
-
45
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
Zhang D.D., Lo S.C., Cross J.V., Templeton D.J., Hannink M. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol. Cell. Biol. 2004, 24:10941-10953.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
46
-
-
33947517977
-
Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease
-
Yamamoto N., Sawada H., Izumi Y., Kume T., Katsuki H., Shimohama S., et al. Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease. J. Biol. Chem. 2007, 282:4364-4372.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4364-4372
-
-
Yamamoto, N.1
Sawada, H.2
Izumi, Y.3
Kume, T.4
Katsuki, H.5
Shimohama, S.6
-
47
-
-
0035947654
-
Hemin-induced activation of the thioredoxin gene by Nrf2: a differential regulation of the antioxidant responsive element by a switch of its binding factors
-
Kim Y.C., Masutani H., Yamaguchi Y., Itoh K., Yamamoto M., Yodoi J. Hemin-induced activation of the thioredoxin gene by Nrf2: a differential regulation of the antioxidant responsive element by a switch of its binding factors. J. Biol. Chem. 2001, 276:18399-18406.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18399-18406
-
-
Kim, Y.C.1
Masutani, H.2
Yamaguchi, Y.3
Itoh, K.4
Yamamoto, M.5
Yodoi, J.6
-
48
-
-
0037468933
-
Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response
-
Kim Y.C., Yamaguchi Y., Kondo N., Masutani H., Yodoi J. Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response. Oncogene 2003, 22:1860-1865.
-
(2003)
Oncogene
, vol.22
, pp. 1860-1865
-
-
Kim, Y.C.1
Yamaguchi, Y.2
Kondo, N.3
Masutani, H.4
Yodoi, J.5
-
49
-
-
33751503096
-
In vivo modulation of the Parkinsonian phenotype by Nrf2
-
Burton N.C., Kensler T.W., Guilarte T.R. In vivo modulation of the Parkinsonian phenotype by Nrf2. Neurotoxicology 2006, 27:1094-1100.
-
(2006)
Neurotoxicology
, vol.27
, pp. 1094-1100
-
-
Burton, N.C.1
Kensler, T.W.2
Guilarte, T.R.3
-
50
-
-
62449132771
-
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: critical role for the astrocyte
-
Chen P.C., Vargas M.R., Pani A.K., Smeyne R.J., Johnson D.A., Kan Y.W., et al. Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: critical role for the astrocyte. Proc. Natl. Acad. Sci. USA 2009, 106:2933-2938.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2933-2938
-
-
Chen, P.C.1
Vargas, M.R.2
Pani, A.K.3
Smeyne, R.J.4
Johnson, D.A.5
Kan, Y.W.6
-
53
-
-
42049090394
-
Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections
-
Cuadrado A., Rojo A.I. Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections. Curr. Pharm. Des. 2008, 14:429-442.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 429-442
-
-
Cuadrado, A.1
Rojo, A.I.2
-
54
-
-
60949108706
-
Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals
-
Mattson M.P., Son T.G., Camandola S. Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals. Dose Response 2007, 5:174-186.
-
(2007)
Dose Response
, vol.5
, pp. 174-186
-
-
Mattson, M.P.1
Son, T.G.2
Camandola, S.3
-
55
-
-
77749339881
-
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease
-
Rojo A.I., Innamorato N.G., Martin-Moreno A.M., De Ceballos M.L., Yamamoto M., Cuadrado A. Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease. Glia 2009, 58:588-598.
-
(2009)
Glia
, vol.58
, pp. 588-598
-
-
Rojo, A.I.1
Innamorato, N.G.2
Martin-Moreno, A.M.3
De Ceballos, M.L.4
Yamamoto, M.5
Cuadrado, A.6
-
56
-
-
47949083810
-
The transcription factor Nrf2 is a therapeutic target against brain inflammation
-
Innamorato N.G., Rojo A.I., Garcia-Yague A.J., Yamamoto M., De Ceballos M.L., Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J. Immunol. 2008, 181:680-689.
-
(2008)
J. Immunol.
, vol.181
, pp. 680-689
-
-
Innamorato, N.G.1
Rojo, A.I.2
Garcia-Yague, A.J.3
Yamamoto, M.4
De Ceballos, M.L.5
Cuadrado, A.6
-
57
-
-
29244479186
-
Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
-
Zhao J., Kobori N., Aronowski J., Dash P.K. Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci. Lett. 2006, 393:108-112.
-
(2006)
Neurosci. Lett.
, vol.393
, pp. 108-112
-
-
Zhao, J.1
Kobori, N.2
Aronowski, J.3
Dash, P.K.4
-
58
-
-
33947379500
-
Protective effect of sulforaphane against dopaminergic cell death
-
Han J.M., Lee Y.J., Lee S.Y., Kim E.M., Moon Y., Kim H.W., et al. Protective effect of sulforaphane against dopaminergic cell death. J. Pharmacol. Exp. Ther. 2007, 321:249-256.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 249-256
-
-
Han, J.M.1
Lee, Y.J.2
Lee, S.Y.3
Kim, E.M.4
Moon, Y.5
Kim, H.W.6
-
59
-
-
60349106093
-
Keap1/Nrf2 system regulates neuronal survival as revealed through study of Keap1 gene-knockout mice
-
Satoh T., Harada N., Hosoya T., Tohyama K., Yamamoto M., Itoh K. Keap1/Nrf2 system regulates neuronal survival as revealed through study of Keap1 gene-knockout mice. Biochem. Biophys. Res. Commun. 2009, 380:298-302.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.380
, pp. 298-302
-
-
Satoh, T.1
Harada, N.2
Hosoya, T.3
Tohyama, K.4
Yamamoto, M.5
Itoh, K.6
-
60
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 1997, 236:313-322.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
-
61
-
-
27844433521
-
PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor
-
Gonzalez-Polo R.A., Carvalho G., Braun T., Decaudin D., Fabre C., Larochette N., et al. PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor. Oncogene 2005, 24:7503-7513.
-
(2005)
Oncogene
, vol.24
, pp. 7503-7513
-
-
Gonzalez-Polo, R.A.1
Carvalho, G.2
Braun, T.3
Decaudin, D.4
Fabre, C.5
Larochette, N.6
-
62
-
-
23844483152
-
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death
-
Gonzalez-Polo R.A., Boya P., Pauleau A.L., Jalil A., Larochette N., Souquere S., et al. The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J. Cell Sci. 2005, 118:3091-3102.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3091-3102
-
-
Gonzalez-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
Jalil, A.4
Larochette, N.5
Souquere, S.6
-
63
-
-
0034667963
-
Clean Western blots of membrane proteins after yeast heterologous expression following a shortened version of the method of Perini et al
-
Fuentes J.M., Lompre A.M., Moller J.V., Falson P., le Maire M. Clean Western blots of membrane proteins after yeast heterologous expression following a shortened version of the method of Perini et al. Anal. Biochem. 2000, 285:276-278.
-
(2000)
Anal. Biochem.
, vol.285
, pp. 276-278
-
-
Fuentes, J.M.1
Lompre, A.M.2
Moller, J.V.3
Falson, P.4
le Maire, M.5
-
64
-
-
68949200471
-
The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death
-
Cristovao A.C., Choi D., Baltazar G., Beal F., Kim Y.S. The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death. Antioxid. Redox Signaling 2009, 11:2105-2118.
-
(2009)
Antioxid. Redox Signaling
, vol.11
, pp. 2105-2118
-
-
Cristovao, A.C.1
Choi, D.2
Baltazar, G.3
Beal, F.4
Kim, Y.S.5
-
65
-
-
33644958235
-
Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells
-
Ouyang M., Shen X. Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 2006, 97:234-244.
-
(2006)
J. Neurochem.
, vol.97
, pp. 234-244
-
-
Ouyang, M.1
Shen, X.2
-
66
-
-
70350028692
-
Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca2+-ATPase
-
Zaidi A., Fernandes D., Bean J.L., Michaelis M.L. Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca2+-ATPase. Free Radic. Biol. Med. 2009, 47:1507-1514.
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 1507-1514
-
-
Zaidi, A.1
Fernandes, D.2
Bean, J.L.3
Michaelis, M.L.4
-
67
-
-
0025912498
-
The role of xanthine oxidase in paraquat intoxication
-
Kitazawa Y., Matsubara M., Takeyama N., Tanaka T. The role of xanthine oxidase in paraquat intoxication. Arch. Biochem. Biophys. 1991, 288:220-224.
-
(1991)
Arch. Biochem. Biophys.
, vol.288
, pp. 220-224
-
-
Kitazawa, Y.1
Matsubara, M.2
Takeyama, N.3
Tanaka, T.4
-
68
-
-
0029046314
-
Xanthine oxidase mediates paraquat-induced toxicity on cultured endothelial cell
-
Sakai M., Yamagami K., Kitazawa Y., Takeyama N., Tanaka T. Xanthine oxidase mediates paraquat-induced toxicity on cultured endothelial cell. Pharmacol. Toxicol. 1995, 77:36-40.
-
(1995)
Pharmacol. Toxicol.
, vol.77
, pp. 36-40
-
-
Sakai, M.1
Yamagami, K.2
Kitazawa, Y.3
Takeyama, N.4
Tanaka, T.5
-
69
-
-
77950547739
-
The roles of ASK family proteins in stress responses and diseases
-
Hattori K., Naguro I., Runchel C., Ichijo H. The roles of ASK family proteins in stress responses and diseases. Cell Commun. Signaling 2009, 7:9.
-
(2009)
Cell Commun. Signaling
, vol.7
, pp. 9
-
-
Hattori, K.1
Naguro, I.2
Runchel, C.3
Ichijo, H.4
-
70
-
-
28544452252
-
Vitamin E supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract, Part 2
-
Pham D.Q., Plakogiannis R. Vitamin E supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract, Part 2. Ann. Pharmacother. 2005, 39:2065-2072.
-
(2005)
Ann. Pharmacother.
, vol.39
, pp. 2065-2072
-
-
Pham, D.Q.1
Plakogiannis, R.2
-
71
-
-
33646773864
-
Antioxidants, supplements, and Parkinson's disease
-
Weber C.A., Ernst M.E. Antioxidants, supplements, and Parkinson's disease. Ann. Pharmacother. 2006, 40:935-938.
-
(2006)
Ann. Pharmacother.
, vol.40
, pp. 935-938
-
-
Weber, C.A.1
Ernst, M.E.2
-
72
-
-
33748374714
-
Use of nutritional supplements in Parkinson's disease patients
-
Wolfrath S.C., Borenstein A.R., Schwartz S., Hauser R.A., Sullivan K.L., Zesiewicz T.A. Use of nutritional supplements in Parkinson's disease patients. Mov. Disord. 2006, 21:1098-1101.
-
(2006)
Mov. Disord.
, vol.21
, pp. 1098-1101
-
-
Wolfrath, S.C.1
Borenstein, A.R.2
Schwartz, S.3
Hauser, R.A.4
Sullivan, K.L.5
Zesiewicz, T.A.6
|