Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

Free Radical Biology and Medicine

Volumn 41, Issue 9, 2006, Pages 1361-1371

  Van Laethem, An ^a   Nys, Kris ^a   Van Kelst, Sofie ^a   Claerhout, Sofie ^a   Ichijo, Hidenori ^b   Vandenheede, Jackie R ^a   Garmyn, Maria ^a   Agostinis, Patrizia ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Apoptosis signal regulating kinase 1; Free radicals; Keratinocytes; p38 MAPK; Reactive oxygen species; UVB radiation

Indexed keywords

AG 1487; APOPTOSIS SIGNAL REGULATING KINASE 1; DIPHENYLIODONIUM SALT; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; KERATINOCYTE; MITOCHONDRION; MOUSE; MUTAGENIC ACTIVITY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RADIATION EXPOSURE; STRESS; ULTRAVIOLET B RADIATION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; FLOW CYTOMETRY; IMMUNOENZYME TECHNIQUES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KERATINOCYTES; MAP KINASE KINASE KINASE 5; MICE; MICE, KNOCKOUT; MITOCHONDRIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

MURINAE;

EID: 33749048083     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.07.007     Document Type: Article

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