Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: Role of ERK1/2 in H2O2-induced cell death

European Journal of Pharmacology

Volumn 483, Issue 2-3, 2004, Pages 163-173

  Ruffels, James ^a   Griffin, Martin ^a   Dickenson, John M ^a  

^a NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

Author keywords

Hydrogen peroxide; MAP (mitogen activated protein) kinase; Neuroblastoma cell; Protein kinase B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; WORTMANNIN;

ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

EID: 0347948518     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.10.032     Document Type: Article

References (51)

1. Ahmed K., Gerber D.A., Cochet C. Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 12:2002;226-230.
2. Alessandrini A., Namura S., Moskowitz M.A., Bonventre J.V. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc. Natl. Acad. Sci. 96:1999;12866-12869.
3. Alexi T., Borlongan C.V., Faull R.L.M., Williams C.E., Clark R.G., Gluckman P.D., Hughes P.E. Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases. Prog. Neurobiol. 60:2000;409-470.
4. Behl C. Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches. Prog. Neurobiol. 57:1999;301-323.
5. Belcheva M.M., Coscia C.J. Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase. Neurosignals. 11:2002;34-44.
6. Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., Leisten J.C., Motiwala A., Pierce S., Satoh Y., Bhagwat S.S., Manning A.M., Anderson D.W. SP 600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. 98:2001;13681-13686.
7. Bielder J.L., Roffler-Tarlov S., Schachner M., Freedman L.S. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38:1978;3751-3757.
8. Brunet A., Datta S.R., Greenberg M.E. Transcription-dependent and -independent control of neuronal survival by the PI-3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11:2001;297-305.
9. Chan P.H. Role of oxidants in ischemic brain damage. Stroke. 27:1996;1124-1129.
10. Chan P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21:2001;2-14.
11. Chandra J., Samali A., Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29:2000;323-333.
12. Cole G.M., Wu K., Timiras P. A culture model for age-related human neurofibrillary pathology. Int. J. Dev. Neurosci. 3:1985;23-32.
13. 2+ and PI3-kinase. J. Neurochem. 80:2002;24-35.
14. Davies S.P., Reddy H., Caivano M., Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:2000;95-105.
15. 1MF-2 smooth muscle cells. Br. J. Pharmacol. 135:2002;1967-1976.
16. Dudley D.T., Pang L., Decker S.J., Bridges A.J., Saltiel A.R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7686-7689.
17. Earnshaw W.C., Martins L.M., Kaufmann S.H. Mammalian caspases: structure, activation, substrates and functions during apoptosis. Annu. Rev. Biochem. 68:1999;383-424.
18. 2 induces up-regulation of Fas and Fas ligand in NGF-differentiated PC12 cells: modulation by cAMP. J. Neurosci. Res. 69:2002;178-188.
19. Farooqui S.M. Induction of adenylate cyclase sensitive dopamine D2-receptors in retinoic acid induced differentiated human neuroblastoma SH-SY5Y cells. Life Sci. 55:1994;1887-1893.
20. Gao Z., Huang K., Xu H. Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in SH-SY5Y cells. Pharmacol. Res. 43:2001;173-178.
21. 1MF-2 cells. Br. J. Pharmacol. 130:2000;867-874.
22. 2: role in cell survival following oxidant injury. J. Biol. Chem. 271:1996;4138-4142.
23. Harper S.J., LoGrasso P. Signalling for survival and death in neurones. The role of stress-activated kinase, JNK and p38. Cell. Signal. 13:2001;299-310.
24. +) causes DNA fragmentation and increases Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms. Brain Res. 704:1995;240-245.
25. Jin K., Mao X.O., Zhu Y., Greenberg D.A. MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad. J. Neurochem. 80:2002;119-125.
26. Kamata H., Hirata H. Redox regulation of cellular signalling. Cell. Signal. 11:1999;1-14.
27. Litchfield D.W. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem. J. 369:2003;1-15.
28. Lowry O.H., Rosebrough N.J., Farr A.C., Randall R.J. Protein measurements with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
29. Maher P. How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. J. Neurosci. 21:2001;2929-2938.
30. Moore J.D., Rothwell N.J., Gibson R.M. Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. Br. J. Pharmacol. 135:2002;1069-1077.
31. Murray B., Alessandrini A., Cole A.J., Yee A.G., Furshpan E.J. Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity. Proc. Natl. Acad. Sci. 95:1998;11975-11980.
32. o are target proteins of reactive oxygen species. Nature. 408:2000;492-495.
33. Oh-hashi K., Maruyama W., Yi H., Takahashi T., Naoi M., Isobe K. Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells. Biochem. Biophys. Res. Commun. 263:1999;504-509.
34. Reed J.C. Apoptosis-regulating proteins as targets for drug discovery. Trends Mol. Med. 7:2001;314-319.
35. 1MF-2 cells. Br. J. Pharmacol. 133:2001;1378-1386.
36. Sastry P.S., Rao K.S. Apoptosis and the nervous system. J. Neurochem. 74:2000;1-20.
37. Satoh T., Nakatsuka D., Watanabe Y., Nagata I., Kituchi H., Namura S. Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons. Neurosci. Lett. 288:2000;163-166.
38. Shimoke K., Yamagishi S., Yamada M., Ikeuchi T., Hatanaka H. Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons. Dev. Brain Res. 112:1999;245-253.
39. Slater A.F.G., Stefan C., Nobel I., van den Dobblesteen D.J., Orrenius S. Intracellular redox changes during apoptosis. Cell Death Differ. 3:1996;57-62.
40. Stanciu M., DeFranco D.B. Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line. J. Biol. Chem. 277:2002;4010-4017.
41. Stanciu M., Wang Y., Kentor R., Burke N., Watkins S., Kress G., Reynolds I., Klann E., Angiolieri M.R., Johnson J.W., DeFranco D.B. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J. Biol. Chem. 275:2000;12200-12206.
42. Strasser A., O'Connor L., Dixit V.M. Apoptosis signalling. Annu. Rev. Biochem. 69:2000;217-245.
43. 2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38 MAPK. Exp. Neurol. 180:2003;144-155.
44. Uberti D., Rizzini C., Spano P.F., Memo M. Characterization of tau proteins in human neuroblastoma SH-SY5Y cell line. Neurosci. Lett. 235:1997;149-153.
45. 2. Eur. J. Pharmacol. 434:2002;17-20.
46. Ushio-Fukai M., Alexander R.W., Akers M., Yin Q., Fujio Y., Walsh K., Griendling K.K. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. J. Biol. Chem. 274:1999;22699-22704.
47. Xia Z., Dickens M., Raingeaud J., Davis R.J., Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1995;1326-1331.
48. 2-induced apoptosis of PC12 cells independent of ceramide formation. Neurol. Res. 22:2000;556-564.
49. Yoshizumi M., Kogame T., Suzaki Y., Fujita Y., Kyaw M., Kirima K., Ishizawa K., Tsuchiya K., Kagami S., Tamaki T. Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells. Br. J. Pharmacol. 136:2002;1023-1032.
50. 2-induced apoptosis in human neuronal cells. Biochem. Biophys. Res. Commun. 235:1997;845-848.
51. Zhang Y., Dawson V.L., Dawson T.M. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol. Dis. 7:2000;240-250.