-
1
-
-
0027365039
-
Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells
-
Adham I.M., Burkhardt E., Benahmed M., Engel W. Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells. J. Biol. Chem. 1993, 268:26668-26672.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26668-26672
-
-
Adham, I.M.1
Burkhardt, E.2
Benahmed, M.3
Engel, W.4
-
2
-
-
34250174577
-
Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway
-
Anand-Ivell R., Heng K., Bartsch O., Ivell R. Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway. Mol. Cell. Endocrinol. 2007, 272:1-13.
-
(2007)
Mol. Cell. Endocrinol.
, vol.272
, pp. 1-13
-
-
Anand-Ivell, R.1
Heng, K.2
Bartsch, O.3
Ivell, R.4
-
3
-
-
44449125052
-
Insulin-like factor 3 levels in amniotic fluid of human male fetuses
-
Anand-Ivell R., Ivell R., Driscoll D., Manson J. Insulin-like factor 3 levels in amniotic fluid of human male fetuses. Hum. Reprod. 2008, 23:1180-1186.
-
(2008)
Hum. Reprod.
, vol.23
, pp. 1180-1186
-
-
Anand-Ivell, R.1
Ivell, R.2
Driscoll, D.3
Manson, J.4
-
4
-
-
33751278205
-
Peripheral INSL3 concentrations decline with age in a large population of Australian men
-
Anand-Ivell R., Wohlgemuth J., Haren M.T., Hope P.J., Hatzinikolas G., Wittert G., Ivell R. Peripheral INSL3 concentrations decline with age in a large population of Australian men. Int. J. Androl. 2006, 29:618-626.
-
(2006)
Int. J. Androl.
, vol.29
, pp. 618-626
-
-
Anand-Ivell, R.1
Wohlgemuth, J.2
Haren, M.T.3
Hope, P.J.4
Hatzinikolas, G.5
Wittert, G.6
Ivell, R.7
-
5
-
-
33645974300
-
Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis
-
Anand-Ivell R.J., Relan V., Balvers M., Coiffec-Dorval I., Fritsch M., Bathgate R.A., Ivell R. Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis. Biol. Reprod. 2006, 74:945-953.
-
(2006)
Biol. Reprod.
, vol.74
, pp. 945-953
-
-
Anand-Ivell, R.J.1
Relan, V.2
Balvers, M.3
Coiffec-Dorval, I.4
Fritsch, M.5
Bathgate, R.A.6
Ivell, R.7
-
6
-
-
0031789308
-
Relaxin-like factor expression as a marker of differentiation in the mouse testis and ovary
-
Balvers M., Spiess A.N., Domagalski R., Hunt N., Kilic E., Mukhopadhyay A.K., Hanks E., Charlton H.M., Ivell R. Relaxin-like factor expression as a marker of differentiation in the mouse testis and ovary. Endocrinology 1998, 139:2960-2970.
-
(1998)
Endocrinology
, vol.139
, pp. 2960-2970
-
-
Balvers, M.1
Spiess, A.N.2
Domagalski, R.3
Hunt, N.4
Kilic, E.5
Mukhopadhyay, A.K.6
Hanks, E.7
Charlton, H.M.8
Ivell, R.9
-
7
-
-
71549143466
-
Swim stress excitation of nucleus incertus and rapid induction of relaxin-3 expression via CRF(1) activation
-
Banerjee A., Shen P.J., Ma S., Bathgate R.A., Gundlach A.L. Swim stress excitation of nucleus incertus and rapid induction of relaxin-3 expression via CRF(1) activation. Neuropharmacology 2010, 58:145-155.
-
(2010)
Neuropharmacology
, vol.58
, pp. 145-155
-
-
Banerjee, A.1
Shen, P.J.2
Ma, S.3
Bathgate, R.A.4
Gundlach, A.L.5
-
8
-
-
0029126464
-
Relaxin-induced increased coronary flow through stimulation of nitric oxide production
-
Bani-Sacchi T., Bigazzi M., Bani D., Mannaioni P.F., Masini E. Relaxin-induced increased coronary flow through stimulation of nitric oxide production. Br. J. Pharmacol. 1995, 116:1589-1594.
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 1589-1594
-
-
Bani-Sacchi, T.1
Bigazzi, M.2
Bani, D.3
Mannaioni, P.F.4
Masini, E.5
-
9
-
-
0031021409
-
Relax a pleiotropic hormone
-
Bani D. Relax a pleiotropic hormone. Gen. Pharmacol. 1997, 28:13-22.
-
(1997)
Gen. Pharmacol.
, vol.28
, pp. 13-22
-
-
Bani, D.1
-
10
-
-
0031810556
-
Relaxin activates the l-arginine-nitric oxide pathway in vascular smooth muscle cells in culture
-
Bani D., Failli P., Bello M.G., Thiemermann C., Bani-Sacchi T., Bigazzi M., Masini E. Relaxin activates the l-arginine-nitric oxide pathway in vascular smooth muscle cells in culture. Hypertension 1998, 31:1240-1247.
-
(1998)
Hypertension
, vol.31
, pp. 1240-1247
-
-
Bani, D.1
Failli, P.2
Bello, M.G.3
Thiemermann, C.4
Bani-Sacchi, T.5
Bigazzi, M.6
Masini, E.7
-
11
-
-
0842312980
-
Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells
-
Bartsch O., Bartlick B., Ivell R. Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells. J. Clin. Endocrinol. Metab. 2004, 89:324-334.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 324-334
-
-
Bartsch, O.1
Bartlick, B.2
Ivell, R.3
-
12
-
-
0029908314
-
Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis
-
Bathgate R., Balvers M., Hunt N., Ivell R. Relaxin-like factor gene is highly expressed in the bovine ovary of the cycle and pregnancy: sequence and messenger ribonucleic acid analysis. Biol. Reprod. 1996, 55:1452-1457.
-
(1996)
Biol. Reprod.
, vol.55
, pp. 1452-1457
-
-
Bathgate, R.1
Balvers, M.2
Hunt, N.3
Ivell, R.4
-
13
-
-
33644589069
-
International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides
-
Bathgate R.A., Ivell R., Sanborn B.M., Sherwood O.D., Summers R.J. International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacol. Rev. 2006, 58:7-31.
-
(2006)
Pharmacol. Rev.
, vol.58
, pp. 7-31
-
-
Bathgate, R.A.1
Ivell, R.2
Sanborn, B.M.3
Sherwood, O.D.4
Summers, R.J.5
-
14
-
-
0037059750
-
Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family
-
Bathgate R.A., Samuel C.S., Burazin T.C., Layfield S., Claasz A.A., Reytomas I.G., Dawson N.F., Zhao C., Bond C., Summers R.J., Parry L.J., Wade J.D., Tregear G.W. Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family. J. Biol. Chem. 2002, 277:1148-1157.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1148-1157
-
-
Bathgate, R.A.1
Samuel, C.S.2
Burazin, T.C.3
Layfield, S.4
Claasz, A.A.5
Reytomas, I.G.6
Dawson, N.F.7
Zhao, C.8
Bond, C.9
Summers, R.J.10
Parry, L.J.11
Wade, J.D.12
Tregear, G.W.13
-
15
-
-
0036082710
-
Purification and characterization of relaxin from the tammar wallaby (Macropus eugenii): bioactivity and expression in the corpus luteum
-
Bathgate R.A., Siebel A.L., Tovote P., Claasz A., Macris M., Tregear G.W., Parry L.J. Purification and characterization of relaxin from the tammar wallaby (Macropus eugenii): bioactivity and expression in the corpus luteum. Biol. Reprod. 2002, 67:293-300.
-
(2002)
Biol. Reprod.
, vol.67
, pp. 293-300
-
-
Bathgate, R.A.1
Siebel, A.L.2
Tovote, P.3
Claasz, A.4
Macris, M.5
Tregear, G.W.6
Parry, L.J.7
-
16
-
-
84884002531
-
Physiology and molecular biology of the relaxin peptide family
-
Elsevier, San Diego, CA, J.D. Neill (Ed.)
-
Bathgate R.A.D., Hsueh A.J., Sherwood O.D. Physiology and molecular biology of the relaxin peptide family. Physiology of Reproduction 2006, 679-770. Elsevier, San Diego, CA. J.D. Neill (Ed.).
-
(2006)
Physiology of Reproduction
, pp. 679-770
-
-
Bathgate, R.A.D.1
Hsueh, A.J.2
Sherwood, O.D.3
-
17
-
-
0344873145
-
Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor
-
Boels K., Schaller H.C. Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor. Br. J. Pharmacol. 2003, 140:932-938.
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 932-938
-
-
Boels, K.1
Schaller, H.C.2
-
18
-
-
33846018526
-
T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane
-
Bogatcheva N.V., Ferlin A., Feng S., Truong A., Gianesello L., Foresta C., Agoulnik A.I. T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane. Am. J. Physiol. Endocrinol. Metab. 2007, 292:E138-E144.
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.292
-
-
Bogatcheva, N.V.1
Ferlin, A.2
Feng, S.3
Truong, A.4
Gianesello, L.5
Foresta, C.6
Agoulnik, A.I.7
-
19
-
-
3242736325
-
Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle
-
Bond C.P., Parry L.J., Samuel C.S., Gehring H.M., Lederman F.L., Rogers P.A., Summers R.J. Increased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycle. J. Clin. Endocrinol. Metab. 2004, 89:3477-3485.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3477-3485
-
-
Bond, C.P.1
Parry, L.J.2
Samuel, C.S.3
Gehring, H.M.4
Lederman, F.L.5
Rogers, P.A.6
Summers, R.J.7
-
20
-
-
0030836515
-
Recombinant human relaxin as a cervical ripening agent
-
Brennand J.E., Calder A.A., Leitch C.R., Greer I.A., Chou M.M., MacKenzie I.Z. Recombinant human relaxin as a cervical ripening agent. Br. J. Obstet. Gynaecol. 1997, 104:775-780.
-
(1997)
Br. J. Obstet. Gynaecol.
, vol.104
, pp. 775-780
-
-
Brennand, J.E.1
Calder, A.A.2
Leitch, C.R.3
Greer, I.A.4
Chou, M.M.5
MacKenzie, I.Z.6
-
22
-
-
0034634628
-
The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction
-
Bullesbach E.E., Schwabe C. The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction. J. Biol. Chem. 2000, 275:35276-35280.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35276-35280
-
-
Bullesbach, E.E.1
Schwabe, C.2
-
23
-
-
0037039453
-
The primary structure and the disulfide links of the bovine relaxin-like factor (RLF)
-
Bullesbach E.E., Schwabe C. The primary structure and the disulfide links of the bovine relaxin-like factor (RLF). Biochemistry 2002, 41:274-281.
-
(2002)
Biochemistry
, vol.41
, pp. 274-281
-
-
Bullesbach, E.E.1
Schwabe, C.2
-
24
-
-
17644415042
-
LGR8 signal activation by the relaxin-like factor
-
Bullesbach E.E., Schwabe C. LGR8 signal activation by the relaxin-like factor. J. Biol. Chem. 2005, 280:14586-14590.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14586-14590
-
-
Bullesbach, E.E.1
Schwabe, C.2
-
25
-
-
17144426920
-
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
-
Bullesbach E.E., Schwabe C. The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7. J. Biol. Chem. 2005, 280:14051-14056.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14051-14056
-
-
Bullesbach, E.E.1
Schwabe, C.2
-
26
-
-
33748746259
-
The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8
-
Bullesbach E.E., Schwabe C. The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8. J. Biol. Chem. 2006, 281:26136-26143.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26136-26143
-
-
Bullesbach, E.E.1
Schwabe, C.2
-
27
-
-
0026497638
-
The receptor-binding site of human relaxin II. A dual prong-binding mechanism
-
Bullesbach E.E., Yang S., Schwabe C. The receptor-binding site of human relaxin II. A dual prong-binding mechanism. J. Biol. Chem. 1992, 267:22957-22960.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22957-22960
-
-
Bullesbach, E.E.1
Yang, S.2
Schwabe, C.3
-
28
-
-
0036734781
-
Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain
-
Burazin T.C., Bathgate R.A., Macris M., Layfield S., Gundlach A.L., Tregear G.W. Restricted, but abundant, expression of the novel rat gene-3 (R3) relaxin in the dorsal tegmental region of brain. J. Neurochem. 2002, 82:1553-1557.
-
(2002)
J. Neurochem.
, vol.82
, pp. 1553-1557
-
-
Burazin, T.C.1
Bathgate, R.A.2
Macris, M.3
Layfield, S.4
Gundlach, A.L.5
Tregear, G.W.6
-
29
-
-
0031787882
-
Relaxin increases the accumulation of new epithelial and stromal cells in the rat cervix during the second half of pregnancy
-
Burger L.L., Sherwood O.D. Relaxin increases the accumulation of new epithelial and stromal cells in the rat cervix during the second half of pregnancy. Endocrinology 1998, 139:3984-3995.
-
(1998)
Endocrinology
, vol.139
, pp. 3984-3995
-
-
Burger, L.L.1
Sherwood, O.D.2
-
30
-
-
69249139614
-
Inactivation of insulin-like factor 6 (Insl6) disrupts the progression of spermatogenesis at late meiotic prophase
-
Burnicka-Turek O., Shirneshan K., Paprotta I., Grzmil P., Meinhardt A., Engel W., Adham I.M. Inactivation of insulin-like factor 6 (Insl6) disrupts the progression of spermatogenesis at late meiotic prophase. Endocrinology 2009, 150:4348-4357.
-
(2009)
Endocrinology
, vol.150
, pp. 4348-4357
-
-
Burnicka-Turek, O.1
Shirneshan, K.2
Paprotta, I.3
Grzmil, P.4
Meinhardt, A.5
Engel, W.6
Adham, I.M.7
-
31
-
-
66149146621
-
Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of {beta}arrestin recruitment
-
Callander G.E., Thomas W.G., Bathgate R.A. Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of {beta}arrestin recruitment. Am. J. Physiol. Cell. Physiol. 2009, 296:C1058-C1066.
-
(2009)
Am. J. Physiol. Cell. Physiol.
, vol.296
-
-
Callander, G.E.1
Thomas, W.G.2
Bathgate, R.A.3
-
32
-
-
0029095815
-
Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta
-
Chassin D., Laurent A., Janneau J.L., Berger R., Bellet D. Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta. Genomics 1995, 29:465-470.
-
(1995)
Genomics
, vol.29
, pp. 465-470
-
-
Chassin, D.1
Laurent, A.2
Janneau, J.L.3
Berger, R.4
Bellet, D.5
-
33
-
-
63249136504
-
Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas
-
Chen B., Wen Y., Yu X.Y., Polan M.L. Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas. Fertil. Steril. 2009, 91:1351-1354.
-
(2009)
Fertil. Steril.
, vol.91
, pp. 1351-1354
-
-
Chen, B.1
Wen, Y.2
Yu, X.Y.3
Polan, M.L.4
-
34
-
-
0024158787
-
The effect of relaxin on cyclic adenosine 3′,5′-monophosphate concentrations in human endometrial glandular epithelial cells
-
Chen G.A., Huang J.R., Tseng L. The effect of relaxin on cyclic adenosine 3′,5′-monophosphate concentrations in human endometrial glandular epithelial cells. Biol. Reprod. 1988, 39:519-525.
-
(1988)
Biol. Reprod.
, vol.39
, pp. 519-525
-
-
Chen, G.A.1
Huang, J.R.2
Tseng, L.3
-
35
-
-
11244333436
-
Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species
-
Chen J., Kuei C., Sutton S.W., Bonaventure P., Nepomuceno D., Eriste E., Sillard R., Lovenberg T.W., Liu C. Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species. J. Pharmacol. Exp. Ther. 2005, 312:83-95.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 83-95
-
-
Chen, J.1
Kuei, C.2
Sutton, S.W.3
Bonaventure, P.4
Nepomuceno, D.5
Eriste, E.6
Sillard, R.7
Lovenberg, T.W.8
Liu, C.9
-
36
-
-
0344564147
-
Identification of INSL5, a new member of the insulin superfamily
-
Conklin D., Lofton-Day C.E., Haldeman B.A., Ching A., Whitmore T.E., Lok S., Jaspers S. Identification of INSL5, a new member of the insulin superfamily. Genomics 1999, 60:50-56.
-
(1999)
Genomics
, vol.60
, pp. 50-56
-
-
Conklin, D.1
Lofton-Day, C.E.2
Haldeman, B.A.3
Ching, A.4
Whitmore, T.E.5
Lok, S.6
Jaspers, S.7
-
37
-
-
44649101927
-
G protein-coupled receptor dimers: functional consequences, disease states and drug targets
-
Dalrymple M.B., Pfleger K.D., Eidne K.A. G protein-coupled receptor dimers: functional consequences, disease states and drug targets. Pharmacol. Ther. 2008, 118:359-371.
-
(2008)
Pharmacol. Ther.
, vol.118
, pp. 359-371
-
-
Dalrymple, M.B.1
Pfleger, K.D.2
Eidne, K.A.3
-
38
-
-
33744955536
-
Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo
-
Del Borgo M.P., Hughes R.A., Bathgate R.A., Lin F., Kawamura K., Wade J.D. Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo. J. Biol. Chem. 2006, 281:13068-13074.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13068-13074
-
-
Del Borgo, M.P.1
Hughes, R.A.2
Bathgate, R.A.3
Lin, F.4
Kawamura, K.5
Wade, J.D.6
-
39
-
-
57149110037
-
Two neuron clusters in the stem of postembryonic zebrafish brain specifically express relaxin-3 gene: first evidence of nucleus incertus in fish
-
Donizetti A., Grossi M., Pariante P., D'Aniello E., Izzo G., Minucci S., Aniello F. Two neuron clusters in the stem of postembryonic zebrafish brain specifically express relaxin-3 gene: first evidence of nucleus incertus in fish. Dev. Dyn. 2008, 237:3864-3869.
-
(2008)
Dev. Dyn.
, vol.237
, pp. 3864-3869
-
-
Donizetti, A.1
Grossi, M.2
Pariante, P.3
D'Aniello, E.4
Izzo, G.5
Minucci, S.6
Aniello, F.7
-
40
-
-
0021990172
-
The physiological role of relaxin in the pregnant rat. III. The influence of relaxin on cervical extensibility
-
Downing S.J., Sherwood O.D. The physiological role of relaxin in the pregnant rat. III. The influence of relaxin on cervical extensibility. Endocrinology 1985, 116:1215-1220.
-
(1985)
Endocrinology
, vol.116
, pp. 1215-1220
-
-
Downing, S.J.1
Sherwood, O.D.2
-
41
-
-
0022578301
-
The physiological role of relaxin in the pregnant rat. IV. The influence of relaxin on cervical collagen and glycosaminoglycans
-
Downing S.J., Sherwood O.D. The physiological role of relaxin in the pregnant rat. IV. The influence of relaxin on cervical collagen and glycosaminoglycans. Endocrinology 1986, 118:471-479.
-
(1986)
Endocrinology
, vol.118
, pp. 471-479
-
-
Downing, S.J.1
Sherwood, O.D.2
-
42
-
-
0037428061
-
Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB
-
Dschietzig T., Bartsch C., Richter C., Laule M., Baumann G., Stangl K. Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB. Circ. Res. 2003, 92:32-40.
-
(2003)
Circ. Res.
, vol.92
, pp. 32-40
-
-
Dschietzig, T.1
Bartsch, C.2
Richter, C.3
Laule, M.4
Baumann, G.5
Stangl, K.6
-
43
-
-
0034810896
-
The pregnancy hormone relaxin is a player in human heart failure
-
Dschietzig T., Richter C., Bartsch C., Laule M., Armbruster F.P., Baumann G., Stangl K. The pregnancy hormone relaxin is a player in human heart failure. FASEB J. 2001, 15:2187-2195.
-
(2001)
FASEB J.
, vol.15
, pp. 2187-2195
-
-
Dschietzig, T.1
Richter, C.2
Bartsch, C.3
Laule, M.4
Armbruster, F.P.5
Baumann, G.6
Stangl, K.7
-
44
-
-
62649155715
-
Intravenous recombinant human relaxin in compensated heart failure: a safety, tolerability, and pharmacodynamic trial
-
Dschietzig T., Teichman S., Unemori E., Wood S., Boehmer J., Richter C., Baumann G., Stangl K. Intravenous recombinant human relaxin in compensated heart failure: a safety, tolerability, and pharmacodynamic trial. J. Card. Fail. 2009, 15:182-190.
-
(2009)
J. Card. Fail.
, vol.15
, pp. 182-190
-
-
Dschietzig, T.1
Teichman, S.2
Unemori, E.3
Wood, S.4
Boehmer, J.5
Richter, C.6
Baumann, G.7
Stangl, K.8
-
45
-
-
12244257489
-
Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype
-
Du X.J., Samuel C.S., Gao X.M., Zhao L., Parry L.J., Tregear G.W. Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype. Cardiovasc. Res. 2003, 57:395-404.
-
(2003)
Cardiovasc. Res.
, vol.57
, pp. 395-404
-
-
Du, X.J.1
Samuel, C.S.2
Gao, X.M.3
Zhao, L.4
Parry, L.J.5
Tregear, G.W.6
-
46
-
-
0022575840
-
Radioimmunoassay of relaxin in pregnancy with an analogue of human relaxin
-
Eddie L.W., Bell R.J., Lester A., Geier M., Bennett G., Johnston P.D., Niall H.D. Radioimmunoassay of relaxin in pregnancy with an analogue of human relaxin. Lancet 1986, 1:1344-1346.
-
(1986)
Lancet
, vol.1
, pp. 1344-1346
-
-
Eddie, L.W.1
Bell, R.J.2
Lester, A.3
Geier, M.4
Bennett, G.5
Johnston, P.D.6
Niall, H.D.7
-
47
-
-
0025812626
-
X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants
-
Eigenbrot C., Randal M., Quan C., Burnier J., O'Connell L., Rinderknecht E., Kossiakoff A.A. X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants. J. Mol. Biol. 1991, 221:15-21.
-
(1991)
J. Mol. Biol.
, vol.221
, pp. 15-21
-
-
Eigenbrot, C.1
Randal, M.2
Quan, C.3
Burnier, J.4
O'Connell, L.5
Rinderknecht, E.6
Kossiakoff, A.A.7
-
49
-
-
64549089247
-
Relaxin supports implantation and early pregnancy in the marmoset monkey
-
Einspanier A., Lieder K., Husen B., Ebert K., Lier S., Einspanier R., Unemori E., Kemper M. Relaxin supports implantation and early pregnancy in the marmoset monkey. Ann. N. Y. Acad. Sci. 2009, 1160:140-146.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 140-146
-
-
Einspanier, A.1
Lieder, K.2
Husen, B.3
Ebert, K.4
Lier, S.5
Einspanier, R.6
Unemori, E.7
Kemper, M.8
-
50
-
-
0034524712
-
Hormonal control of gubernaculum development during testis descent: gubernaculum outgrowth in vitro requires both insulin-like factor and androgen
-
Emmen J.M., McLuskey A., Adham I.M., Engel W., Grootegoed J.A., Brinkmann A.O. Hormonal control of gubernaculum development during testis descent: gubernaculum outgrowth in vitro requires both insulin-like factor and androgen. Endocrinology 2000, 141:4720-4727.
-
(2000)
Endocrinology
, vol.141
, pp. 4720-4727
-
-
Emmen, J.M.1
McLuskey, A.2
Adham, I.M.3
Engel, W.4
Grootegoed, J.A.5
Brinkmann, A.O.6
-
51
-
-
0032858945
-
Relationship of serum levels of endogenous relaxin to cervical size in the second trimester and to cervical ripening at term
-
Eppel W., Kucera E., Bieglmayer C. Relationship of serum levels of endogenous relaxin to cervical size in the second trimester and to cervical ripening at term. Br. J. Obstet. Gynaecol. 1999, 106:917-923.
-
(1999)
Br. J. Obstet. Gynaecol.
, vol.106
, pp. 917-923
-
-
Eppel, W.1
Kucera, E.2
Bieglmayer, C.3
-
52
-
-
0028354924
-
Characterization of two relaxin genes in the chimpanzee
-
Evans B.A., Fu P., Tregear G.W. Characterization of two relaxin genes in the chimpanzee. J. Endocrinol. 1994, 140:385-392.
-
(1994)
J. Endocrinol.
, vol.140
, pp. 385-392
-
-
Evans, B.A.1
Fu, P.2
Tregear, G.W.3
-
53
-
-
0027229592
-
The mouse relaxin gene: nucleotide sequence and expression
-
Evans B.A., John M., Fowler K.J., Summers R.J., Cronk M., Shine J., Tregear G.W. The mouse relaxin gene: nucleotide sequence and expression. J. Mol. Endocrinol. 1993, 10:15-23.
-
(1993)
J. Mol. Endocrinol.
, vol.10
, pp. 15-23
-
-
Evans, B.A.1
John, M.2
Fowler, K.J.3
Summers, R.J.4
Cronk, M.5
Shine, J.6
Tregear, G.W.7
-
54
-
-
12744280744
-
Structure of human follicle-stimulating hormone in complex with its receptor
-
Fan Q.R., Hendrickson W.A. Structure of human follicle-stimulating hormone in complex with its receptor. Nature 2005, 433:269-277.
-
(2005)
Nature
, vol.433
, pp. 269-277
-
-
Fan, Q.R.1
Hendrickson, W.A.2
-
55
-
-
0025164162
-
Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells-a specific and high throughput in vitro bioassay
-
Fei D.T., Gross M.C., Lofgren J.L., Mora-Worms M., Chen A.B. Cyclic AMP response to recombinant human relaxin by cultured human endometrial cells-a specific and high throughput in vitro bioassay. Biochem. Biophys. Res. Commun. 1990, 170:214-222.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.170
, pp. 214-222
-
-
Fei, D.T.1
Gross, M.C.2
Lofgren, J.L.3
Mora-Worms, M.4
Chen, A.B.5
-
56
-
-
23644438200
-
Genetic targeting of relaxin and insl3 signaling in mice
-
Feng S., Bogatcheva N.V., Kamat A.A., Agoulnik A.I. Genetic targeting of relaxin and insl3 signaling in mice. Ann. N. Y. Acad. Sci. 2005, 1041:82-90.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 82-90
-
-
Feng, S.1
Bogatcheva, N.V.2
Kamat, A.A.3
Agoulnik, A.I.4
-
57
-
-
33748987068
-
Paracrine and endocrine roles of insulin-like factor 3
-
Ferlin A., Arredi B., Zuccarello D., Garolla A., Selice R., Foresta C. Paracrine and endocrine roles of insulin-like factor 3. J. Endocrinol. Invest. 2006, 29:657-664.
-
(2006)
J. Endocrinol. Invest.
, vol.29
, pp. 657-664
-
-
Ferlin, A.1
Arredi, B.2
Zuccarello, D.3
Garolla, A.4
Selice, R.5
Foresta, C.6
-
58
-
-
33748749893
-
Changes in serum insulin-like factor 3 during normal male puberty
-
Ferlin A., Garolla A., Rigon F., Rasi Caldogno L., Lenzi A., Foresta C. Changes in serum insulin-like factor 3 during normal male puberty. J. Clin. Endocrinol. Metab. 2006, 91:3426-3431.
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 3426-3431
-
-
Ferlin, A.1
Garolla, A.2
Rigon, F.3
Rasi Caldogno, L.4
Lenzi, A.5
Foresta, C.6
-
59
-
-
64549159376
-
New roles for INSL3 in adults
-
Ferlin A., Pepe A., Gianesello L., Garolla A., Feng S., Facciolli A., Morello R., Agoulnik A.I., Foresta C. New roles for INSL3 in adults. Ann. N. Y. Acad. Sci. 2009, 1160:215-218.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 215-218
-
-
Ferlin, A.1
Pepe, A.2
Gianesello, L.3
Garolla, A.4
Feng, S.5
Facciolli, A.6
Morello, R.7
Agoulnik, A.I.8
Foresta, C.9
-
60
-
-
42449137005
-
Mutations in the insulin-like factor 3 receptor are associated with osteoporosis
-
Ferlin A., Pepe A., Gianesello L., Garolla A., Feng S., Giannini S., Zaccolo M., Facciolli A., Morello R., Agoulnik A.I., Foresta C. Mutations in the insulin-like factor 3 receptor are associated with osteoporosis. J. Bone Miner. Res. 2008, 23:683-693.
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 683-693
-
-
Ferlin, A.1
Pepe, A.2
Gianesello, L.3
Garolla, A.4
Feng, S.5
Giannini, S.6
Zaccolo, M.7
Facciolli, A.8
Morello, R.9
Agoulnik, A.I.10
Foresta, C.11
-
62
-
-
12144291562
-
Relaxin regulation of endometrial structure and function in the rhesus monkey
-
Goldsmith L.T., Weiss G., Palejwala S., Plant T.M., Wojtczuk A., Lambert W.C., Ammur N., Heller D., Skurnick J.H., Edwards D., Cole D.M. Relaxin regulation of endometrial structure and function in the rhesus monkey. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:4685-4689.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 4685-4689
-
-
Goldsmith, L.T.1
Weiss, G.2
Palejwala, S.3
Plant, T.M.4
Wojtczuk, A.5
Lambert, W.C.6
Ammur, N.7
Heller, D.8
Skurnick, J.H.9
Edwards, D.10
Cole, D.M.11
-
63
-
-
0037106428
-
Mutations of the GREAT gene cause cryptorchidism
-
Gorlov I.P., Kamat A., Bogatcheva N.V., Jones E., Lamb D.J., Truong A., Bishop C.E., McElreavey K., Agoulnik A.I. Mutations of the GREAT gene cause cryptorchidism. Hum. Mol. Genet. 2002, 11:2309-2318.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2309-2318
-
-
Gorlov, I.P.1
Kamat, A.2
Bogatcheva, N.V.3
Jones, E.4
Lamb, D.J.5
Truong, A.6
Bishop, C.E.7
McElreavey, K.8
Agoulnik, A.I.9
-
64
-
-
0023723483
-
Monoclonal antibodies specific for rat relaxin. II. Passive immunization with monoclonal antibodies throughout the second half of pregnancy disrupts birth in intact rats
-
Guico-Lamm M.L., Sherwood O.D. Monoclonal antibodies specific for rat relaxin. II. Passive immunization with monoclonal antibodies throughout the second half of pregnancy disrupts birth in intact rats. Endocrinology 1988, 123:2479-2485.
-
(1988)
Endocrinology
, vol.123
, pp. 2479-2485
-
-
Guico-Lamm, M.L.1
Sherwood, O.D.2
-
65
-
-
23644442600
-
Signaling pathways of the LGR7 and LGR8 receptors determined by reporter genes
-
Halls M.L., Bathgate R.A., Roche P.J., Summers R.J. Signaling pathways of the LGR7 and LGR8 receptors determined by reporter genes. Ann. N. Y. Acad. Sci. 2005, 1041:292-295.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 292-295
-
-
Halls, M.L.1
Bathgate, R.A.2
Roche, P.J.3
Summers, R.J.4
-
66
-
-
23644456397
-
Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors
-
Halls M.L., Bathgate R.A., Sudo S., Kumagai J., Bond C.P., Summers R.J. Identification of binding sites with differing affinity and potency for relaxin analogues on LGR7 and LGR8 receptors. Ann. N. Y. Acad. Sci. 2005, 1041:17-21.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 17-21
-
-
Halls, M.L.1
Bathgate, R.A.2
Sudo, S.3
Kumagai, J.4
Bond, C.P.5
Summers, R.J.6
-
67
-
-
33745226248
-
Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms
-
Halls M.L., Bathgate R.A., Summers R.J. Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms. Mol. Pharmacol. 2006, 70:214-226.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 214-226
-
-
Halls, M.L.1
Bathgate, R.A.2
Summers, R.J.3
-
68
-
-
33845939640
-
Comparison of signaling pathways activated by the relaxin family peptide receptors, RXFP1 and RXFP2, using reporter genes
-
Halls M.L., Bathgate R.A., Summers R.J. Comparison of signaling pathways activated by the relaxin family peptide receptors, RXFP1 and RXFP2, using reporter genes. J. Pharmacol. Exp. Ther. 2007, 320:281-290.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.320
, pp. 281-290
-
-
Halls, M.L.1
Bathgate, R.A.2
Summers, R.J.3
-
69
-
-
64549095557
-
Relaxin activates multiple cAMP signaling pathway profiles in different target cells
-
Halls M.L., Hewitson T.D., Moore X.L., Du X.J., Bathgate R.A., Summers R.J. Relaxin activates multiple cAMP signaling pathway profiles in different target cells. Ann. N. Y. Acad. Sci. 2009, 1160:108-111.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 108-111
-
-
Halls, M.L.1
Hewitson, T.D.2
Moore, X.L.3
Du, X.J.4
Bathgate, R.A.5
Summers, R.J.6
-
70
-
-
69249158290
-
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
-
Han Y., Moreira I.S., Urizar E., Weinstein H., Javitch J.A. Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation. Nat. Chem. Biol. 2009, 5:688-695.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 688-695
-
-
Han, Y.1
Moreira, I.S.2
Urizar, E.3
Weinstein, H.4
Javitch, J.A.5
-
71
-
-
64549155679
-
Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function
-
Hartley B.J., Scott D.J., Callander G.E., Wilkinson T.N., Ganella D.E., Kong C.K.S.L., Ferraro T., Petrie E.J.., Bathgate R.A. Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function. Ann. N. Y. Acad. Sci. 2009, 1160:67-73.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 67-73
-
-
Hartley, B.J.1
Scott, D.J.2
Callander, G.E.3
Wilkinson, T.N.4
Ganella, D.E.5
Kong, C.K.S.L.6
Ferraro, T.7
Petrie, E.J..8
Bathgate, R.A.9
-
72
-
-
64849117347
-
Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework
-
Haugaard-Jonsson L.M., Hossain M.A., Daly N.L., Craik D.J., Wade J.D., Rosengren K.J. Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. Biochem. J. 2009, 419:619-627.
-
(2009)
Biochem. J.
, vol.419
, pp. 619-627
-
-
Haugaard-Jonsson, L.M.1
Hossain, M.A.2
Daly, N.L.3
Craik, D.J.4
Wade, J.D.5
Rosengren, K.J.6
-
73
-
-
58249103037
-
Relaxin signalling in primary cultures of human myometrial cells
-
Heng K., Ivell R., Wagaarachchi P., Anand-Ivell R. Relaxin signalling in primary cultures of human myometrial cells. Mol. Hum. Reprod. 2008, 14:603-611.
-
(2008)
Mol. Hum. Reprod.
, vol.14
, pp. 603-611
-
-
Heng, K.1
Ivell, R.2
Wagaarachchi, P.3
Anand-Ivell, R.4
-
74
-
-
0003412980
-
Experimental relaxation of the pubic ligament of the guinea pig
-
Hisaw F.L. Experimental relaxation of the pubic ligament of the guinea pig. Proc. Soc. Exp. Biol. Med. 1926, 23:661-663.
-
(1926)
Proc. Soc. Exp. Biol. Med.
, vol.23
, pp. 661-663
-
-
Hisaw, F.L.1
-
75
-
-
23644436539
-
Relaxin induces matrix metalloproteinase-9 through activation of nuclear factor kappa B in human THP-1 cells
-
Ho T.Y., Bagnell C.A. Relaxin induces matrix metalloproteinase-9 through activation of nuclear factor kappa B in human THP-1 cells. Ann. N. Y. Acad. Sci. 2005, 1041:314-316.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 314-316
-
-
Ho, T.Y.1
Bagnell, C.A.2
-
76
-
-
23644432627
-
The human LGR7 low-density lipoprotein class A module requires calcium for structure
-
Hopkins E.J., Bathgate R.A., Gooley P.R. The human LGR7 low-density lipoprotein class A module requires calcium for structure. Ann. N. Y. Acad. Sci. 2005, 1041:27-34.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 27-34
-
-
Hopkins, E.J.1
Bathgate, R.A.2
Gooley, P.R.3
-
77
-
-
33947501041
-
The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation
-
Hopkins E.J., Layfield S., Ferraro T., Bathgate R.A., Gooley P.R. The NMR solution structure of the relaxin (RXFP1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation. J. Biol. Chem. 2007, 282:4172-4184.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4172-4184
-
-
Hopkins, E.J.1
Layfield, S.2
Ferraro, T.3
Bathgate, R.A.4
Gooley, P.R.5
-
78
-
-
47749116027
-
The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors
-
Hossain M.A., Rosengren K.J., Haugaard-Jonsson L.M., Zhang S., Layfield S., Ferraro T., Daly N.L., Tregear G.W., Wade J.D., Bathgate R.A. The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors. J. Biol. Chem. 2008, 283:17287-17297.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17287-17297
-
-
Hossain, M.A.1
Rosengren, K.J.2
Haugaard-Jonsson, L.M.3
Zhang, S.4
Layfield, S.5
Ferraro, T.6
Daly, N.L.7
Tregear, G.W.8
Wade, J.D.9
Bathgate, R.A.10
-
79
-
-
0033310863
-
Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney
-
Hsu S.Y. Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney. Mol. Endocrinol. 1999, 13:2163-2174.
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 2163-2174
-
-
Hsu, S.Y.1
-
80
-
-
0042836864
-
New insights into the evolution of the relaxin-LGR signaling system
-
Hsu S.Y. New insights into the evolution of the relaxin-LGR signaling system. Trends Endocrinol. Metab. 2003, 14:303-309.
-
(2003)
Trends Endocrinol. Metab.
, vol.14
, pp. 303-309
-
-
Hsu, S.Y.1
-
81
-
-
0034464024
-
The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7
-
Hsu S.Y., Kudo M., Chen T., Nakabayashi K., Bhalla A., van der Spek P.J., van Duin M., Hsueh A.J.W. The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol. Endocrinol. 2000, 14:1257-1271.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1257-1271
-
-
Hsu, S.Y.1
Kudo, M.2
Chen, T.3
Nakabayashi, K.4
Bhalla, A.5
van der Spek, P.J.6
van Duin, M.7
Hsueh, A.J.W.8
-
82
-
-
0037169071
-
Activation of orphan receptors by the hormone relaxin
-
Hsu S.Y., Nakabayashi K., Nishi S., Kumagai J., Kudo M., Sherwood O.D., Hsueh A.J. Activation of orphan receptors by the hormone relaxin. Science 2002, 295:671-674.
-
(2002)
Science
, vol.295
, pp. 671-674
-
-
Hsu, S.Y.1
Nakabayashi, K.2
Nishi, S.3
Kumagai, J.4
Kudo, M.5
Sherwood, O.D.6
Hsueh, A.J.7
-
83
-
-
0034464024
-
The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7
-
Hsu Y.S., Kudo M., Chen T., Nakabayashi K., Bhalla A., van der Spek M.D., Hsueh A.J. The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol. Endocrinol. 2000, 14:1257-1271.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1257-1271
-
-
Hsu, Y.S.1
Kudo, M.2
Chen, T.3
Nakabayashi, K.4
Bhalla, A.5
van der Spek, M.D.6
Hsueh, A.J.7
-
84
-
-
0020681051
-
Structure of a genomic clone encoding biologically active human relaxin
-
Hudson P., Haley J., John M., Cronk M., Crawford R., Haralambidis J., Tregear G., Shine J., Niall H. Structure of a genomic clone encoding biologically active human relaxin. Nature 1983, 301:628-631.
-
(1983)
Nature
, vol.301
, pp. 628-631
-
-
Hudson, P.1
Haley, J.2
John, M.3
Cronk, M.4
Crawford, R.5
Haralambidis, J.6
Tregear, G.7
Shine, J.8
Niall, H.9
-
85
-
-
0021514136
-
Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones
-
Hudson P., John M., Crawford R., Haralambidis J., Scanlon D., Gorman J., Tregear G., Shine J., Niall H. Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones. EMBO J. 1984, 3:2333-2339.
-
(1984)
EMBO J.
, vol.3
, pp. 2333-2339
-
-
Hudson, P.1
John, M.2
Crawford, R.3
Haralambidis, J.4
Scanlon, D.5
Gorman, J.6
Tregear, G.7
Shine, J.8
Niall, H.9
-
86
-
-
0025748154
-
Monoclonal antibodies specific for rat relaxin. V. Passive immunization with monoclonal antibodies throughout the second half of pregnancy disrupts development of the mammary apparatus and, hence, lactational performance in rats
-
Hwang J.J., Lee A.B., Fields P.A., Haab L.M., Mojonnier L.E., Sherwood O.D. Monoclonal antibodies specific for rat relaxin. V. Passive immunization with monoclonal antibodies throughout the second half of pregnancy disrupts development of the mammary apparatus and, hence, lactational performance in rats. Endocrinology 1991, 129:3034-3042.
-
(1991)
Endocrinology
, vol.129
, pp. 3034-3042
-
-
Hwang, J.J.1
Lee, A.B.2
Fields, P.A.3
Haab, L.M.4
Mojonnier, L.E.5
Sherwood, O.D.6
-
87
-
-
0024365335
-
Monoclonal antibodies specific for rat relaxin. IV. Passive immunization with monoclonal antibodies during the antepartum period reduces cervical growth and extensibility, disrupts birth, and reduces pup survival in intact rats
-
Hwang J.J., Shanks R.D., Sherwood O.D. Monoclonal antibodies specific for rat relaxin. IV. Passive immunization with monoclonal antibodies during the antepartum period reduces cervical growth and extensibility, disrupts birth, and reduces pup survival in intact rats. Endocrinology 1989, 125:260-266.
-
(1989)
Endocrinology
, vol.125
, pp. 260-266
-
-
Hwang, J.J.1
Shanks, R.D.2
Sherwood, O.D.3
-
88
-
-
0023715508
-
Monoclonal antibodies specific for rat relaxin. III. Passive immunization with monoclonal antibodies throughout the second half of pregnancy reduces cervical growth and extensibility in intact rats
-
Hwang J.J., Sherwood O.D. Monoclonal antibodies specific for rat relaxin. III. Passive immunization with monoclonal antibodies throughout the second half of pregnancy reduces cervical growth and extensibility in intact rats. Endocrinology 1988, 123:2486-2490.
-
(1988)
Endocrinology
, vol.123
, pp. 2486-2490
-
-
Hwang, J.J.1
Sherwood, O.D.2
-
89
-
-
0036200341
-
Dynamic changes in the expression of relaxin-like factor (INSL3), cholesterol side-chain cleavage cytochrome p450, and 3beta-hydroxysteroid dehydrogenase in bovine ovarian follicles during growth and atresia
-
Irving-Rodgers H.F., Bathgate R.A., Ivell R., Domagalski R., Rodgers R.J. Dynamic changes in the expression of relaxin-like factor (INSL3), cholesterol side-chain cleavage cytochrome p450, and 3beta-hydroxysteroid dehydrogenase in bovine ovarian follicles during growth and atresia. Biol. Reprod. 2002, 66:934-943.
-
(2002)
Biol. Reprod.
, vol.66
, pp. 934-943
-
-
Irving-Rodgers, H.F.1
Bathgate, R.A.2
Ivell, R.3
Domagalski, R.4
Rodgers, R.J.5
-
90
-
-
3242688248
-
Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates
-
Ivell R., Balvers M., Pohnke Y., Telgmann R., Bartsch O., Milde-Langosch K., Bamberger A.M., Einspanier A. Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates. Reprod. Biol. Endocrinol. 2003, 1:114.
-
(2003)
Reprod. Biol. Endocrinol.
, vol.1
, pp. 114
-
-
Ivell, R.1
Balvers, M.2
Pohnke, Y.3
Telgmann, R.4
Bartsch, O.5
Milde-Langosch, K.6
Bamberger, A.M.7
Einspanier, A.8
-
91
-
-
0036721334
-
Reproductive biology of the relaxin-like factor (RLF/INSL3)
-
Ivell R., Bathgate R.A. Reproductive biology of the relaxin-like factor (RLF/INSL3). Biol. Reprod. 2002, 67:699-705.
-
(2002)
Biol. Reprod.
, vol.67
, pp. 699-705
-
-
Ivell, R.1
Bathgate, R.A.2
-
93
-
-
77949569485
-
The genomics of INSL5
-
Kluwer, Dordrecht, G.W. Tregear (Ed.)
-
Jaspers S., Lok S., Lofton-Day C.E., Haldeman B.A., Whitmore T.E., Foley K.P., Conklin D. The genomics of INSL5. Relaxin 2000: Proceedings of the Third International Conference on Relaxin and Related Peptides 2001, Kluwer, Dordrecht. G.W. Tregear (Ed.).
-
(2001)
Relaxin 2000: Proceedings of the Third International Conference on Relaxin and Related Peptides
-
-
Jaspers, S.1
Lok, S.2
Lofton-Day, C.E.3
Haldeman, B.A.4
Whitmore, T.E.5
Foley, K.P.6
Conklin, D.7
-
94
-
-
38749130120
-
The vascular actions of relaxin
-
Jeyabalan A., Shroff S.G., Novak J., Conrad K.P. The vascular actions of relaxin. Adv. Exp. Med. Biol. 2007, 612:65-87.
-
(2007)
Adv. Exp. Med. Biol.
, vol.612
, pp. 65-87
-
-
Jeyabalan, A.1
Shroff, S.G.2
Novak, J.3
Conrad, K.P.4
-
95
-
-
0019445927
-
Limited sequence homology between porcine and rat relaxins: implications for physiological studies
-
John M.J., Borjesson B.W., Walsh J.R., Niall H.D. Limited sequence homology between porcine and rat relaxins: implications for physiological studies. Endocrinology 1981, 108:726-729.
-
(1981)
Endocrinology
, vol.108
, pp. 726-729
-
-
John, M.J.1
Borjesson, B.W.2
Walsh, J.R.3
Niall, H.D.4
-
96
-
-
4644313216
-
Genetic targeting of relaxin and insulin-like factor 3 receptors in mice
-
Kamat A.A., Feng S., Bogatcheva N.V., Truong A., Bishop C.E., Agoulnik A.I. Genetic targeting of relaxin and insulin-like factor 3 receptors in mice. Endocrinology 2004, 145:4712-4720.
-
(2004)
Endocrinology
, vol.145
, pp. 4712-4720
-
-
Kamat, A.A.1
Feng, S.2
Bogatcheva, N.V.3
Truong, A.4
Bishop, C.E.5
Agoulnik, A.I.6
-
97
-
-
0034463049
-
Identification, chromosomal mapping, and partial characterization of mouse InsI6: a new member of the insulin family
-
Kasik J., Muglia L., Stephan D.A., Menon R.K. Identification, chromosomal mapping, and partial characterization of mouse InsI6: a new member of the insulin family. Endocrinology 2000, 141:458-461.
-
(2000)
Endocrinology
, vol.141
, pp. 458-461
-
-
Kasik, J.1
Muglia, L.2
Stephan, D.A.3
Menon, R.K.4
-
98
-
-
2442485845
-
Paracrine regulation of mammalian oocyte maturation and male germ cell survival
-
Kawamura K., Kumagai J., Sudo S., Chun S.Y., Pisarska M., Morita H., Toppari J., Fu P., Wade J.D., Bathgate R.A., Hsueh A.J. Paracrine regulation of mammalian oocyte maturation and male germ cell survival. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:7323-7328.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 7323-7328
-
-
Kawamura, K.1
Kumagai, J.2
Sudo, S.3
Chun, S.Y.4
Pisarska, M.5
Morita, H.6
Toppari, J.7
Fu, P.8
Wade, J.D.9
Bathgate, R.A.10
Hsueh, A.J.11
-
99
-
-
33847071711
-
The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane
-
Kern A., Agoulnik A.I., Bryant-Greenwood G.D. The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane. Endocrinology 2007, 148:1181-1194.
-
(2007)
Endocrinology
, vol.148
, pp. 1181-1194
-
-
Kern, A.1
Agoulnik, A.I.2
Bryant-Greenwood, G.D.3
-
100
-
-
66449122003
-
Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells
-
Kern A., Bryant-Greenwood G.D. Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells. Endocrinology 2009, 150:2419-2428.
-
(2009)
Endocrinology
, vol.150
, pp. 2419-2428
-
-
Kern, A.1
Bryant-Greenwood, G.D.2
-
101
-
-
40849096162
-
Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes
-
Kern A., Hubbard D., Amano A., Bryant-Greenwood G.D. Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes. Endocrinology 2008, 149:1277-1294.
-
(2008)
Endocrinology
, vol.149
, pp. 1277-1294
-
-
Kern, A.1
Hubbard, D.2
Amano, A.3
Bryant-Greenwood, G.D.4
-
102
-
-
0027718173
-
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
-
Kobe B., Deisenhofer J. Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 2003, 366:751-756.
-
(2003)
Nature
, vol.366
, pp. 751-756
-
-
Kobe, B.1
Deisenhofer, J.2
-
103
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B., Kajava A.V. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 2001, 11:725-732.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
104
-
-
0031710135
-
Identification of specific relaxin-binding cells in the human female
-
Kohsaka T., Min G., Lukas G., Trupin S., Campbell E.T., Sherwood O.D. Identification of specific relaxin-binding cells in the human female. Biol. Reprod. 1998, 59:991-999.
-
(1998)
Biol. Reprod.
, vol.59
, pp. 991-999
-
-
Kohsaka, T.1
Min, G.2
Lukas, G.3
Trupin, S.4
Campbell, E.T.5
Sherwood, O.D.6
-
105
-
-
0029786504
-
Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family
-
Koman A., Cazaubon S., Couraud P.O., Ullrich A., Strosberg A.D. Molecular characterization and in vitro biological activity of placentin, a new member of the insulin gene family. J. Biol. Chem. 1996, 271:20238-20241.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20238-20241
-
-
Koman, A.1
Cazaubon, S.2
Couraud, P.O.3
Ullrich, A.4
Strosberg, A.D.5
-
106
-
-
0036849160
-
Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): effect of pertussis toxin
-
Kompa A.R., Samuel C.S., Summers R.J. Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): effect of pertussis toxin. Br. J. Pharmacol. 2002, 137:710-718.
-
(2002)
Br. J. Pharmacol.
, vol.137
, pp. 710-718
-
-
Kompa, A.R.1
Samuel, C.S.2
Summers, R.J.3
-
107
-
-
0347986674
-
Impaired nipple development and parturition in LGR7 knockout mice
-
Krajnc-Franken M.A., van Disseldorp A.J., Koenders J.E., Mosselman S., van Duin M., Gossen J.A. Impaired nipple development and parturition in LGR7 knockout mice. Mol. Cell. Biol. 2004, 24:687-696.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 687-696
-
-
Krajnc-Franken, M.A.1
van Disseldorp, A.J.2
Koenders, J.E.3
Mosselman, S.4
van Duin, M.5
Gossen, J.A.6
-
108
-
-
0037999625
-
The action of aqueous corpus luteum extract upon uterine activity
-
Krantz J.C., Bryant H.H., Carr C.J. The action of aqueous corpus luteum extract upon uterine activity. Surg. Gynecol. Obstet. 1950, 90:372-375.
-
(1950)
Surg. Gynecol. Obstet.
, vol.90
, pp. 372-375
-
-
Krantz, J.C.1
Bryant, H.H.2
Carr, C.J.3
-
109
-
-
0031747997
-
The role of receptor kinases and arrestins in G protein-coupled receptor regulation
-
Krupnick J.G., Benovic J.L. The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu. Rev. Pharmacol. Toxicol. 1998, 38:289-319.
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 289-319
-
-
Krupnick, J.G.1
Benovic, J.L.2
-
110
-
-
34249695006
-
Expression of leucine-rich repeat-containing G-protein-coupled receptors in the human cyclic endometrium
-
Krusche C.A., Kroll T., Beier H.M., Classen-Linke I. Expression of leucine-rich repeat-containing G-protein-coupled receptors in the human cyclic endometrium. Fertil. Steril. 2007, 87:1428-1437.
-
(2007)
Fertil. Steril.
, vol.87
, pp. 1428-1437
-
-
Krusche, C.A.1
Kroll, T.2
Beier, H.M.3
Classen-Linke, I.4
-
111
-
-
0035043428
-
Leydig insulin-like hormone, gubernacular development and testicular descent
-
Kubota Y., Nef S., Farmer P.J., Temelcos C., Parada L.F., Hutson J.M. Leydig insulin-like hormone, gubernacular development and testicular descent. J. Urol. 2001, 165:1673-1675.
-
(2001)
J. Urol.
, vol.165
, pp. 1673-1675
-
-
Kubota, Y.1
Nef, S.2
Farmer, P.J.3
Temelcos, C.4
Parada, L.F.5
Hutson, J.M.6
-
112
-
-
0036798057
-
The role of insulin 3, testosterone, Mullerian inhibiting substance and relaxin in rat gubernacular growth
-
Kubota Y., Temelcos C., Bathgate R.A., Smith K.J., Scott D., Zhao C., Hutson J.M. The role of insulin 3, testosterone, Mullerian inhibiting substance and relaxin in rat gubernacular growth. Mol. Hum. Reprod. 2002, 8:900-905.
-
(2002)
Mol. Hum. Reprod.
, vol.8
, pp. 900-905
-
-
Kubota, Y.1
Temelcos, C.2
Bathgate, R.A.3
Smith, K.J.4
Scott, D.5
Zhao, C.6
Hutson, J.M.7
-
113
-
-
34548471964
-
R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization
-
Kuei C., Sutton S., Bonaventure P., Pudiak C., Shelton J., Zhu J., Nepomuceno D., Wu J., Chen J., Kamme F., Seierstad M., Hack M.D., Bathgate R.A., Hossain M.A., Wade J.D., Atack J., Lovenberg T.W., Liu C. R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization. J. Biol. Chem. 2007, 282:25425-25435.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 25425-25435
-
-
Kuei, C.1
Sutton, S.2
Bonaventure, P.3
Pudiak, C.4
Shelton, J.5
Zhu, J.6
Nepomuceno, D.7
Wu, J.8
Chen, J.9
Kamme, F.10
Seierstad, M.11
Hack, M.D.12
Bathgate, R.A.13
Hossain, M.A.14
Wade, J.D.15
Atack, J.16
Lovenberg, T.W.17
Liu, C.18
-
114
-
-
0029054871
-
Relaxin acts directly on rat mammary nipples to stimulate their growth
-
Kuenzi M.J., Connolly B.A., Sherwood O.D. Relaxin acts directly on rat mammary nipples to stimulate their growth. Endocrinology 1995, 136:2943-2947.
-
(1995)
Endocrinology
, vol.136
, pp. 2943-2947
-
-
Kuenzi, M.J.1
Connolly, B.A.2
Sherwood, O.D.3
-
115
-
-
0037200034
-
INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent
-
Kumagai J., Hsu S.Y., Matsumi H., Roh J.S., Fu P., Wade J.D., Bathgate R.A., Hsueh A.J. INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent. J. Biol. Chem. 2002, 277:31283-31286.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31283-31286
-
-
Kumagai, J.1
Hsu, S.Y.2
Matsumi, H.3
Roh, J.S.4
Fu, P.5
Wade, J.D.6
Bathgate, R.A.7
Hsueh, A.J.8
-
116
-
-
0031658301
-
Insulin-like 4 (INSL4) gene expression in human embryonic and trophoblastic tissues
-
Laurent A., Rouillac C., Delezoide A.L., Giovangrandi Y., Vekemans M., Bellet D., Abitbol M., Vidaud M. Insulin-like 4 (INSL4) gene expression in human embryonic and trophoblastic tissues. Mol. Reprod. Dev. 1998, 51:123-129.
-
(1998)
Mol. Reprod. Dev.
, vol.51
, pp. 123-129
-
-
Laurent, A.1
Rouillac, C.2
Delezoide, A.L.3
Giovangrandi, Y.4
Vekemans, M.5
Bellet, D.6
Abitbol, M.7
Vidaud, M.8
-
117
-
-
23244443050
-
Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats
-
Lekgabe E.D., Kiriazis H., Zhao C., Xu Q., Moore X.L., Su Y., Bathgate R.A., Du X.J., Samuel C.S. Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats. Hypertension 2005, 46:412-418.
-
(2005)
Hypertension
, vol.46
, pp. 412-418
-
-
Lekgabe, E.D.1
Kiriazis, H.2
Zhao, C.3
Xu, Q.4
Moore, X.L.5
Su, Y.6
Bathgate, R.A.7
Du, X.J.8
Samuel, C.S.9
-
118
-
-
0034878781
-
Relaxin increases secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 during uterine and cervical growth and remodeling in the pig
-
Lenhart J.A., Ryan P.L., Ohleth K.M., Palmer S.S., Bagnell C.A. Relaxin increases secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 during uterine and cervical growth and remodeling in the pig. Endocrinology 2001, 142:3941-3949.
-
(2001)
Endocrinology
, vol.142
, pp. 3941-3949
-
-
Lenhart, J.A.1
Ryan, P.L.2
Ohleth, K.M.3
Palmer, S.S.4
Bagnell, C.A.5
-
119
-
-
2342499088
-
Synthetic human insulin 4 does not activate the G-protein-coupled receptors LGR7 or LGR8
-
Lin F., Otvos L., Kumagai J., Tregear G.W., Bathgate R.A., Wade J.D. Synthetic human insulin 4 does not activate the G-protein-coupled receptors LGR7 or LGR8. J. Pept. Sci. 2004, 10:257-264.
-
(2004)
J. Pept. Sci.
, vol.10
, pp. 257-264
-
-
Lin, F.1
Otvos, L.2
Kumagai, J.3
Tregear, G.W.4
Bathgate, R.A.5
Wade, J.D.6
-
120
-
-
11244347812
-
Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7
-
Liu C., Chen J., Kuei C., Sutton S., Nepomuceno D., Bonaventure P., Lovenberg T.W. Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. Mol. Pharmacol. 2005, 67:231-240.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 231-240
-
-
Liu, C.1
Chen, J.2
Kuei, C.3
Sutton, S.4
Nepomuceno, D.5
Bonaventure, P.6
Lovenberg, T.W.7
-
121
-
-
0346118862
-
Identification of relaxin-3/INSL7 as a ligand for GPCR142
-
Liu C., Chen J., Sutton S., Roland B., Kuei C., Farmer N., Sillard R., Lovenberg T.W. Identification of relaxin-3/INSL7 as a ligand for GPCR142. J. Biol. Chem. 2003, 278:50765-50770.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50765-50770
-
-
Liu, C.1
Chen, J.2
Sutton, S.3
Roland, B.4
Kuei, C.5
Farmer, N.6
Sillard, R.7
Lovenberg, T.W.8
-
122
-
-
10744224962
-
Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135
-
Liu C., Eriste E., Sutton S., Chen J., Roland B., Kuei C., Farmer N., Jornvall H., Sillard R., Lovenberg T.W. Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135. J. Biol. Chem. 2003, 278:50754-50764.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50754-50764
-
-
Liu, C.1
Eriste, E.2
Sutton, S.3
Chen, J.4
Roland, B.5
Kuei, C.6
Farmer, N.7
Jornvall, H.8
Sillard, R.9
Lovenberg, T.W.10
-
123
-
-
19944432343
-
INSL5 is a high affinity specific agonist for GPCR142 (GPR100)
-
Liu C., Kuei C., Sutton S., Chen J., Bonaventure P., Wu J., Nepomuceno D., Kamme F., Tran D.T., Zhu J., Wilkinson T., Bathgate R., Eriste E., Sillard R., Lovenberg T.W. INSL5 is a high affinity specific agonist for GPCR142 (GPR100). J. Biol. Chem. 2005, 280:292-300.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 292-300
-
-
Liu, C.1
Kuei, C.2
Sutton, S.3
Chen, J.4
Bonaventure, P.5
Wu, J.6
Nepomuceno, D.7
Kamme, F.8
Tran, D.T.9
Zhu, J.10
Wilkinson, T.11
Bathgate, R.12
Eriste, E.13
Sillard, R.14
Lovenberg, T.W.15
-
124
-
-
0034033108
-
Identification of INSL6, a new member of the insulin family that is expressed in the testis of the human and rat
-
Lok S., Johnston D.S., Conklin D., Lofton-Day C.E., Adams R.L., Jelmberg A.C., Whitmore T.E., Schrader S., Griswold M.D., Jaspers S.R. Identification of INSL6, a new member of the insulin family that is expressed in the testis of the human and rat. Biol. Reprod. 2000, 62:1593-1599.
-
(2000)
Biol. Reprod.
, vol.62
, pp. 1593-1599
-
-
Lok, S.1
Johnston, D.S.2
Conklin, D.3
Lofton-Day, C.E.4
Adams, R.L.5
Jelmberg, A.C.6
Whitmore, T.E.7
Schrader, S.8
Griswold, M.D.9
Jaspers, S.R.10
-
125
-
-
1042268781
-
Gene expression pattern and immunoreactive protein localization of LGR7 receptor in human endometrium throughout the menstrual cycle
-
Luna J.J., Riesewijk A., Horcajadas J.A., Van Os Rd R., Dominguez F., Mosselman S., Pellicer A., Simon C. Gene expression pattern and immunoreactive protein localization of LGR7 receptor in human endometrium throughout the menstrual cycle. Mol. Hum. Reprod. 2004, 10:85-90.
-
(2004)
Mol. Hum. Reprod.
, vol.10
, pp. 85-90
-
-
Luna, J.J.1
Riesewijk, A.2
Horcajadas, J.A.3
Van Os Rd, R.4
Dominguez, F.5
Mosselman, S.6
Pellicer, A.7
Simon, C.8
-
126
-
-
33751503663
-
Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat
-
Ma S., Bonaventure P., Ferraro T., Shen P.J., Burazin T.C., Bathgate R.A., Liu C., Tregear G.W., Sutton S.W., Gundlach A.L. Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat. Neuroscience 2007, 144:165-190.
-
(2007)
Neuroscience
, vol.144
, pp. 165-190
-
-
Ma, S.1
Bonaventure, P.2
Ferraro, T.3
Shen, P.J.4
Burazin, T.C.5
Bathgate, R.A.6
Liu, C.7
Tregear, G.W.8
Sutton, S.W.9
Gundlach, A.L.10
-
127
-
-
38749090956
-
Relaxin-family peptide and receptor systems in brain: insights from recent anatomical and functional studies
-
Ma S., Gundlach A.L. Relaxin-family peptide and receptor systems in brain: insights from recent anatomical and functional studies. Adv. Exp. Med. Biol. 2007, 612:119-137.
-
(2007)
Adv. Exp. Med. Biol.
, vol.612
, pp. 119-137
-
-
Ma, S.1
Gundlach, A.L.2
-
128
-
-
0026707533
-
Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones
-
Marriott D., Gillece-Castro B., Gorman C.M. Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones. Mol. Endocrinol. 1992, 6:1441-1450.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1441-1450
-
-
Marriott, D.1
Gillece-Castro, B.2
Gorman, C.M.3
-
129
-
-
0034595301
-
The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors
-
Matsumoto M., Kamohara M., Sugimoto T., Hidaka K., Takasaki J., Saito T., Okada M., Yamaguchi T., Furuichi K. The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors. Gene 2000, 248:183-189.
-
(2000)
Gene
, vol.248
, pp. 183-189
-
-
Matsumoto, M.1
Kamohara, M.2
Sugimoto, T.3
Hidaka, K.4
Takasaki, J.5
Saito, T.6
Okada, M.7
Yamaguchi, T.8
Furuichi, K.9
-
130
-
-
3242882918
-
Disparate effects of relaxin and TGFbeta1: relaxin increases, but TGFbeta1 inhibits, the relaxin receptor and the production of IGFBP-1 in human endometrial stromal/decidual cells
-
Mazella J., Tang M., Tseng L. Disparate effects of relaxin and TGFbeta1: relaxin increases, but TGFbeta1 inhibits, the relaxin receptor and the production of IGFBP-1 in human endometrial stromal/decidual cells. Hum. Reprod. 2004, 19:1513-1518.
-
(2004)
Hum. Reprod.
, vol.19
, pp. 1513-1518
-
-
Mazella, J.1
Tang, M.2
Tseng, L.3
-
131
-
-
64549109754
-
Relaxin-3 and its role in neuroendocrine function
-
McGowan B.M., Stanley S.A., Ghatei M.A., Bloom S.R. Relaxin-3 and its role in neuroendocrine function. Ann. N. Y. Acad. Sci. 2009, 1160:250-255.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 250-255
-
-
McGowan, B.M.1
Stanley, S.A.2
Ghatei, M.A.3
Bloom, S.R.4
-
132
-
-
23044454976
-
Central relaxin-3 administration causes hyperphagia in male Wistar rats
-
McGowan B.M., Stanley S.A., Smith K.L., White N.E., Connolly M.M., Thompson E.L., Gardiner J.V., Murphy K.G., Ghatei M.A., Bloom S.R. Central relaxin-3 administration causes hyperphagia in male Wistar rats. Endocrinology 2005, 146:3295-3300.
-
(2005)
Endocrinology
, vol.146
, pp. 3295-3300
-
-
McGowan, B.M.1
Stanley, S.A.2
Smith, K.L.3
White, N.E.4
Connolly, M.M.5
Thompson, E.L.6
Gardiner, J.V.7
Murphy, K.G.8
Ghatei, M.A.9
Bloom, S.R.10
-
133
-
-
64549148901
-
Role of relaxin in maternal systemic and renal vascular adaptations during gestation
-
McGuane J.T., Debrah J.E., Debrah D.O., Rubin J.P., Segal M., Shroff S.G., Conrad K.P. Role of relaxin in maternal systemic and renal vascular adaptations during gestation. Ann. N. Y. Acad. Sci. 2009, 1160:304-312.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 304-312
-
-
McGuane, J.T.1
Debrah, J.E.2
Debrah, D.O.3
Rubin, J.P.4
Segal, M.5
Shroff, S.G.6
Conrad, K.P.7
-
134
-
-
34548757535
-
The role of GPCR dimerisation/oligomerisation in receptor signalling
-
Milligan G., Canals M., Pediani J.D., Ellis J., Lopez-Gimenez J.F. The role of GPCR dimerisation/oligomerisation in receptor signalling. Ernst Schering Found. Symp. Proc. 2006, 145-161.
-
(2006)
Ernst Schering Found. Symp. Proc.
, pp. 145-161
-
-
Milligan, G.1
Canals, M.2
Pediani, J.D.3
Ellis, J.4
Lopez-Gimenez, J.F.5
-
135
-
-
65349122390
-
Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2
-
Mookerjee I., Hewitson T.D., Halls M.L., Summers R.J., Mathai M.L., Bathgate R.A., Tregear G.W., Samuel C.S. Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2. FASEB J. 2009, 23:1219-1229.
-
(2009)
FASEB J.
, vol.23
, pp. 1219-1229
-
-
Mookerjee, I.1
Hewitson, T.D.2
Halls, M.L.3
Summers, R.J.4
Mathai, M.L.5
Bathgate, R.A.6
Tregear, G.W.7
Samuel, C.S.8
-
136
-
-
30944442868
-
Endogenous relaxin regulates collagen deposition in an animal model of allergic airway disease
-
Mookerjee I., Solly N.R., Royce S.G., Tregear G.W., Samuel C.S., Tang M.L. Endogenous relaxin regulates collagen deposition in an animal model of allergic airway disease. Endocrinology 2006, 147:754-761.
-
(2006)
Endocrinology
, vol.147
, pp. 754-761
-
-
Mookerjee, I.1
Solly, N.R.2
Royce, S.G.3
Tregear, G.W.4
Samuel, C.S.5
Tang, M.L.6
-
137
-
-
33947379636
-
Relaxin antagonizes hypertrophy and apoptosis in neonatal rat cardiomyocytes
-
Moore X.L., Tan S.L., Lo C.Y., Fang L., Su Y.D., Gao X.M., Woodcock E.A., Summers R.J., Tregear G.W., Bathgate R.A., Du X.J. Relaxin antagonizes hypertrophy and apoptosis in neonatal rat cardiomyocytes. Endocrinology 2007, 148:1582-1589.
-
(2007)
Endocrinology
, vol.148
, pp. 1582-1589
-
-
Moore, X.L.1
Tan, S.L.2
Lo, C.Y.3
Fang, L.4
Su, Y.D.5
Gao, X.M.6
Woodcock, E.A.7
Summers, R.J.8
Tregear, G.W.9
Bathgate, R.A.10
Du, X.J.11
-
138
-
-
27144555675
-
Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity
-
Muda M., He C., Martini P.G., Ferraro T., Layfield S., Taylor D., Chevrier C., Schweickhardt R., Kelton C., Ryan P.L., Bathgate R.A. Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity. Mol. Hum. Reprod. 2005, 11:591-600.
-
(2005)
Mol. Hum. Reprod.
, vol.11
, pp. 591-600
-
-
Muda, M.1
He, C.2
Martini, P.G.3
Ferraro, T.4
Layfield, S.5
Taylor, D.6
Chevrier, C.7
Schweickhardt, R.8
Kelton, C.9
Ryan, P.L.10
Bathgate, R.A.11
-
139
-
-
0032989104
-
Cryptorchidism in mice mutant for Insl3
-
Nef S., Parada L.F. Cryptorchidism in mice mutant for Insl3. Nat. Genet. 1999, 22:295-299.
-
(1999)
Nat. Genet.
, vol.22
, pp. 295-299
-
-
Nef, S.1
Parada, L.F.2
-
140
-
-
23644441514
-
Relaxin stimulates cAMP production in MCF-7 cells upon overexpression of type V adenylyl cyclase
-
Nguyen B.T., Dessauer C.W. Relaxin stimulates cAMP production in MCF-7 cells upon overexpression of type V adenylyl cyclase. Ann. N. Y. Acad. Sci. 2005, 1041:296-299.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 296-299
-
-
Nguyen, B.T.1
Dessauer, C.W.2
-
141
-
-
0037503879
-
Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3′,5′-monophosphate by relaxin
-
Nguyen B.T., Yang L., Sanborn B.M., Dessauer C.W. Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3′,5′-monophosphate by relaxin. Mol. Endocrinol. 2003, 17:1075-1084.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1075-1084
-
-
Nguyen, B.T.1
Yang, L.2
Sanborn, B.M.3
Dessauer, C.W.4
-
142
-
-
0036783987
-
Effects of orchiopexy on congenitally cryptorchid insulin-3 knockout mice
-
Nguyen M.T., Showalter P.R., Timmons C.F., Nef S., Parada L.F., Baker L.A. Effects of orchiopexy on congenitally cryptorchid insulin-3 knockout mice. J. Urol. 2002, 168:1779-1783.
-
(2002)
J. Urol.
, vol.168
, pp. 1779-1783
-
-
Nguyen, M.T.1
Showalter, P.R.2
Timmons, C.F.3
Nef, S.4
Parada, L.F.5
Baker, L.A.6
-
143
-
-
4344564007
-
Relaxin receptors and nitric oxide synthases: search for the missing link
-
Nistri S., Bani D. Relaxin receptors and nitric oxide synthases: search for the missing link. Reprod. Biol. Endocrinol. 2003, 1:5.
-
(2003)
Reprod. Biol. Endocrinol.
, vol.1
, pp. 5
-
-
Nistri, S.1
Bani, D.2
-
144
-
-
0024380902
-
Hormonal control of the cervix in pregnant gilts. II. Relaxin promotes changes in the physical properties of the cervix in ovariectomized hormone-treated pregnant gilts
-
O'Day M.B., Winn R.J., Easter R.A., Dziuk P.J., Sherwood O.D. Hormonal control of the cervix in pregnant gilts. II. Relaxin promotes changes in the physical properties of the cervix in ovariectomized hormone-treated pregnant gilts. Endocrinology 1989, 125:3004-3010.
-
(1989)
Endocrinology
, vol.125
, pp. 3004-3010
-
-
O'Day, M.B.1
Winn, R.J.2
Easter, R.A.3
Dziuk, P.J.4
Sherwood, O.D.5
-
145
-
-
0025311303
-
Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain
-
Osheroff P.L., Ling V.T., Vandlen R.L., Cronin M.J., Lofgren J.A. Preparation of biologically active 32P-labeled human relaxin. Displaceable binding to rat uterus, cervix, and brain. J. Biol. Chem. 1990, 265:9396-9401.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 9396-9401
-
-
Osheroff, P.L.1
Ling, V.T.2
Vandlen, R.L.3
Cronin, M.J.4
Lofgren, J.A.5
-
146
-
-
0035019760
-
A transgenic insertion causing cryptorchidism in mice
-
Overbeek P.A., Gorlov I.P., Sutherland R.W., Houston J.B., Harrison W.R., Boettger-Tong H.L., Bishop C.E., Agoulnik A.I. A transgenic insertion causing cryptorchidism in mice. Genesis 2001, 30:26-35.
-
(2001)
Genesis
, vol.30
, pp. 26-35
-
-
Overbeek, P.A.1
Gorlov, I.P.2
Sutherland, R.W.3
Houston, J.B.4
Harrison, W.R.5
Boettger-Tong, H.L.6
Bishop, C.E.7
Agoulnik, A.I.8
-
147
-
-
57649131054
-
Regulation of receptor signaling by relaxin A chain motifs: derivation of pan-specific and LGR7-specific human relaxin analogs
-
Park J.I., Semyonov J., Yi W., Chang C.L., Hsu S.Y. Regulation of receptor signaling by relaxin A chain motifs: derivation of pan-specific and LGR7-specific human relaxin analogs. J. Biol. Chem. 2008, 283:32099-32109.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 32099-32109
-
-
Park, J.I.1
Semyonov, J.2
Yi, W.3
Chang, C.L.4
Hsu, S.Y.5
-
148
-
-
0036972315
-
The expression of the RLF/INSL3 gene is reduced in Leydig cells of the aging rat testis
-
Paust H.J., Wessels J., Ivell R., Mukhopadhyay A.K. The expression of the RLF/INSL3 gene is reduced in Leydig cells of the aging rat testis. Exp. Gerontol. 2002, 37:1461-1467.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 1461-1467
-
-
Paust, H.J.1
Wessels, J.2
Ivell, R.3
Mukhopadhyay, A.K.4
-
149
-
-
0028941369
-
Variations in serum relaxin (hRLX-2) concentrations during human pregnancy
-
Petersen L.K., Vogel I., Agger A.O., Westergard J., Nils M., Uldbjerg N. Variations in serum relaxin (hRLX-2) concentrations during human pregnancy. Acta Obstet. Gynecol. Scand. 1995, 74:251-256.
-
(1995)
Acta Obstet. Gynecol. Scand.
, vol.74
, pp. 251-256
-
-
Petersen, L.K.1
Vogel, I.2
Agger, A.O.3
Westergard, J.4
Nils, M.5
Uldbjerg, N.6
-
150
-
-
36248970132
-
Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
-
Rasmussen S.G., Choi H.J., Rosenbaum D.M., Kobilka T.S., Thian F.S., Edwards P.C., Burghammer M., Ratnala V.R., Sanishvili R., Fischetti R.F., Schertler G.F., Weis W.I., Kobilka B.K. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature 2007, 450:383-387.
-
(2007)
Nature
, vol.450
, pp. 383-387
-
-
Rasmussen, S.G.1
Choi, H.J.2
Rosenbaum, D.M.3
Kobilka, T.S.4
Thian, F.S.5
Edwards, P.C.6
Burghammer, M.7
Ratnala, V.R.8
Sanishvili, R.9
Fischetti, R.F.10
Schertler, G.F.11
Weis, W.I.12
Kobilka, B.K.13
-
151
-
-
33646832952
-
Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3
-
Rosengren K.J., Lin F., Bathgate R.A., Tregear G.W., Daly N.L., Wade J.D., Craik D.J. Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3. J. Biol. Chem. 2006, 281:5845-5851.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5845-5851
-
-
Rosengren, K.J.1
Lin, F.2
Bathgate, R.A.3
Tregear, G.W.4
Daly, N.L.5
Wade, J.D.6
Craik, D.J.7
-
152
-
-
33748762210
-
Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3
-
Rosengren K.J., Zhang S., Lin F., Daly N.L., Scott D.J., Hughes R.A., Bathgate R.A., Craik D.J., Wade J.D. Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3. J. Biol. Chem. 2006, 281:28287-28295.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28287-28295
-
-
Rosengren, K.J.1
Zhang, S.2
Lin, F.3
Daly, N.L.4
Scott, D.J.5
Hughes, R.A.6
Bathgate, R.A.7
Craik, D.J.8
Wade, J.D.9
-
153
-
-
33646522213
-
Relaxin in cardiovascular and renal disease
-
Samuel C.S., Hewitson T.D. Relaxin in cardiovascular and renal disease. Kidney Int. 2006, 69:1498-1502.
-
(2006)
Kidney Int.
, vol.69
, pp. 1498-1502
-
-
Samuel, C.S.1
Hewitson, T.D.2
-
154
-
-
4344606223
-
Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo
-
Samuel C.S., Unemori E.N., Mookerjee I., Bathgate R.A., Layfield S.L., Mak J., Tregear G.W., Du X.J. Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo. Endocrinology 2004, 145:4125-4133.
-
(2004)
Endocrinology
, vol.145
, pp. 4125-4133
-
-
Samuel, C.S.1
Unemori, E.N.2
Mookerjee, I.3
Bathgate, R.A.4
Layfield, S.L.5
Mak, J.6
Tregear, G.W.7
Du, X.J.8
-
155
-
-
0037271801
-
Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis
-
Samuel C.S., Zhao C., Bathgate R.A., Bond C.P., Burton M.D., Parry L.J., Summers R.J., Tang M.L., Amento E.P., Tregear G.W. Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis. FASEB J. 2003, 17:121-123.
-
(2003)
FASEB J.
, vol.17
, pp. 121-123
-
-
Samuel, C.S.1
Zhao, C.2
Bathgate, R.A.3
Bond, C.P.4
Burton, M.D.5
Parry, L.J.6
Summers, R.J.7
Tang, M.L.8
Amento, E.P.9
Tregear, G.W.10
-
156
-
-
2442647519
-
Relaxin-1-deficient mice develop an age-related progression of renal fibrosis
-
Samuel C.S., Zhao C., Bond C.P., Hewitson T.D., Amento E.P., Summers R.J. Relaxin-1-deficient mice develop an age-related progression of renal fibrosis. Kidney Int. 2004, 65:2054-2064.
-
(2004)
Kidney Int.
, vol.65
, pp. 2054-2064
-
-
Samuel, C.S.1
Zhao, C.2
Bond, C.P.3
Hewitson, T.D.4
Amento, E.P.5
Summers, R.J.6
-
158
-
-
23644441614
-
Characterization of the rat INSL3 receptor
-
Scott D.J., Fu P., Shen P.J., Gundlach A., Layfield S., Riesewijk A., Tomiyama H., Hutson J.M., Tregear G.W., Bathgate R.A. Characterization of the rat INSL3 receptor. Ann. N. Y. Acad. Sci. 2005, 1041:13-16.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 13-16
-
-
Scott, D.J.1
Fu, P.2
Shen, P.J.3
Gundlach, A.4
Layfield, S.5
Riesewijk, A.6
Tomiyama, H.7
Hutson, J.M.8
Tregear, G.W.9
Bathgate, R.A.10
-
159
-
-
9344227938
-
Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat-containing G-protein-coupled receptor 7
-
Scott D.J., Layfield S., Riesewijk A., Morita H., Tregear G.W., Bathgate R.A. Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat-containing G-protein-coupled receptor 7. Clin. Exp. Pharmacol. Physiol. 2004, 31:828-832.
-
(2004)
Clin. Exp. Pharmacol. Physiol.
, vol.31
, pp. 828-832
-
-
Scott, D.J.1
Layfield, S.2
Riesewijk, A.3
Morita, H.4
Tregear, G.W.5
Bathgate, R.A.6
-
160
-
-
33845933437
-
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules
-
Scott D.J., Layfield S., Yan Y., Sudo S., Hsueh A.J., Tregear G.W., Bathgate R.A. Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules. J. Biol. Chem. 2006, 281:34942-34954.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34942-34954
-
-
Scott, D.J.1
Layfield, S.2
Yan, Y.3
Sudo, S.4
Hsueh, A.J.5
Tregear, G.W.6
Bathgate, R.A.7
-
161
-
-
23644452138
-
LGR7-truncate is a splice variant of the relaxin receptor LGR7 and is a relaxin antagonist in vitro
-
Scott D.J., Tregear G.W., Bathgate R.A. LGR7-truncate is a splice variant of the relaxin receptor LGR7 and is a relaxin antagonist in vitro. Ann. N. Y. Acad. Sci. 2005, 1041:22-26.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 22-26
-
-
Scott, D.J.1
Tregear, G.W.2
Bathgate, R.A.3
-
162
-
-
64549145456
-
Modeling the primary hormone-binding site of RXFP1 and RXFP2
-
Scott D.J., Tregear G.W., Bathgate R.A. Modeling the primary hormone-binding site of RXFP1 and RXFP2. Ann. N. Y. Acad. Sci. 2009, 1160:74-77.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 74-77
-
-
Scott, D.J.1
Tregear, G.W.2
Bathgate, R.A.3
-
163
-
-
34347270603
-
Defining the LGR8 residues involved in binding insulin-like peptide 3
-
Scott D.J., Wilkinson T.N., Zhang S., Ferraro T., Wade J.D., Tregear G.W., Bathgate R.A. Defining the LGR8 residues involved in binding insulin-like peptide 3. Mol. Endocrinol. 2007, 21:1699-1712.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 1699-1712
-
-
Scott, D.J.1
Wilkinson, T.N.2
Zhang, S.3
Ferraro, T.4
Wade, J.D.5
Tregear, G.W.6
Bathgate, R.A.7
-
164
-
-
0018888075
-
Radioimmunoassay of relaxin throughout pregnancy and during parturition in the rat
-
Sherwood O.D., Crnekovic V.E., Gordon W.L., Rutherford J.E. Radioimmunoassay of relaxin throughout pregnancy and during parturition in the rat. Endocrinology 1980, 107:691-698.
-
(1980)
Endocrinology
, vol.107
, pp. 691-698
-
-
Sherwood, O.D.1
Crnekovic, V.E.2
Gordon, W.L.3
Rutherford, J.E.4
-
165
-
-
0035143742
-
Increase in final stages of follicular atresia and premature decay of corpora lutea in Insl3-deficient mice
-
Spanel-Borowski K., Schafer I., Zimmermann S., Engel W., Adham I.M. Increase in final stages of follicular atresia and premature decay of corpora lutea in Insl3-deficient mice. Mol. Reprod. Dev. 2001, 58:281-286.
-
(2001)
Mol. Reprod. Dev.
, vol.58
, pp. 281-286
-
-
Spanel-Borowski, K.1
Schafer, I.2
Zimmermann, S.3
Engel, W.4
Adham, I.M.5
-
166
-
-
0025299143
-
Relaxin in the peri-implantation period
-
Stewart D.R., Celniker A.C., Taylor C.A., Cragun J.R., Overstreet J.W., Lasley B.L. Relaxin in the peri-implantation period. J. Clin. Endocrinol. Metab. 1990, 70:1771-1773.
-
(1990)
J. Clin. Endocrinol. Metab.
, vol.70
, pp. 1771-1773
-
-
Stewart, D.R.1
Celniker, A.C.2
Taylor, C.A.3
Cragun, J.R.4
Overstreet, J.W.5
Lasley, B.L.6
-
167
-
-
0037424265
-
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
-
Sudo S., Kumagai J., Nishi S., Layfield S., Ferraro T., Bathgate R.A., Hsueh A.J. H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J. Biol. Chem. 2003, 278:7855-7862.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7855-7862
-
-
Sudo, S.1
Kumagai, J.2
Nishi, S.3
Layfield, S.4
Ferraro, T.5
Bathgate, R.A.6
Hsueh, A.J.7
-
168
-
-
0037022389
-
Circulating relaxin acts on subfornical organ neurons to stimulate water drinking in the rat
-
Sunn N., Egli M., Burazin T.C., Burns P., Colvill L., Davern P., Denton D.A., Oldfield B.J., Weisinger R.S., Rauch M., Schmid H.A., McKinley M.J. Circulating relaxin acts on subfornical organ neurons to stimulate water drinking in the rat. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:1701-1706.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 1701-1706
-
-
Sunn, N.1
Egli, M.2
Burazin, T.C.3
Burns, P.4
Colvill, L.5
Davern, P.6
Denton, D.A.7
Oldfield, B.J.8
Weisinger, R.S.9
Rauch, M.10
Schmid, H.A.11
McKinley, M.J.12
-
169
-
-
15544378102
-
Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing
-
Sutton S.W., Bonaventure P., Kuei C., Roland B., Chen J., Nepomuceno D., Lovenberg T.W., Liu C. Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing. Neuroendocrinology 2004, 80:298-307.
-
(2004)
Neuroendocrinology
, vol.80
, pp. 298-307
-
-
Sutton, S.W.1
Bonaventure, P.2
Kuei, C.3
Roland, B.4
Chen, J.5
Nepomuceno, D.6
Lovenberg, T.W.7
Liu, C.8
-
170
-
-
64549134236
-
Metabolic and neuroendocrine responses to RXFP3 modulation in the central nervous system
-
Sutton S.W., Shelton J., Smith C., Williams J., Yun S., Motley T., Kuei C., Bonaventure P., Gundlach A., Liu C., Lovenberg T. Metabolic and neuroendocrine responses to RXFP3 modulation in the central nervous system. Ann. N. Y. Acad. Sci. 2009, 1160:242-249.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 242-249
-
-
Sutton, S.W.1
Shelton, J.2
Smith, C.3
Williams, J.4
Yun, S.5
Motley, T.6
Kuei, C.7
Bonaventure, P.8
Gundlach, A.9
Liu, C.10
Lovenberg, T.11
-
171
-
-
40849119953
-
Cooperative binding of insulin-like peptide 3 to a dimeric relaxin family peptide receptor 2
-
Svendsen A.M., Vrecl M., Ellis T.M., Heding A., Kristensen J.B., Wade J.D., Bathgate R.A., De Meyts P., Nohr J. Cooperative binding of insulin-like peptide 3 to a dimeric relaxin family peptide receptor 2. Endocrinology 2008, 149:1113-1120.
-
(2008)
Endocrinology
, vol.149
, pp. 1113-1120
-
-
Svendsen, A.M.1
Vrecl, M.2
Ellis, T.M.3
Heding, A.4
Kristensen, J.B.5
Wade, J.D.6
Bathgate, R.A.7
De Meyts, P.8
Nohr, J.9
-
172
-
-
56049100923
-
Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1
-
Svendsen A.M., Zalesko A., Konig J., Vrecl M., Heding A., Kristensen J.B., Wade J.D., Bathgate R.A., De Meyts P., Nohr J. Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1. Mol. Cell. Endocrinol. 2008, 296:10-17.
-
(2008)
Mol. Cell. Endocrinol.
, vol.296
, pp. 10-17
-
-
Svendsen, A.M.1
Zalesko, A.2
Konig, J.3
Vrecl, M.4
Heding, A.5
Kristensen, J.B.6
Wade, J.D.7
Bathgate, R.A.8
De Meyts, P.9
Nohr, J.10
-
173
-
-
0031988974
-
Comparison of relaxin receptors in rat isolated atria and uterus by use of synthetic and native relaxin analogues
-
Tan Y.Y., Wade J.D., Tregear G.W., Summers R.J. Comparison of relaxin receptors in rat isolated atria and uterus by use of synthetic and native relaxin analogues. Br. J. Pharmacol. 1998, 123:762-770.
-
(1998)
Br. J. Pharmacol.
, vol.123
, pp. 762-770
-
-
Tan, Y.Y.1
Wade, J.D.2
Tregear, G.W.3
Summers, R.J.4
-
174
-
-
0032908730
-
Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: characterization and effects of oestrogen treatment
-
Tan Y.Y., Wade J.D., Tregear G.W., Summers R.J. Quantitative autoradiographic studies of relaxin binding in rat atria, uterus and cerebral cortex: characterization and effects of oestrogen treatment. Br. J. Pharmacol. 1999, 127:91-98.
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 91-98
-
-
Tan, Y.Y.1
Wade, J.D.2
Tregear, G.W.3
Summers, R.J.4
-
175
-
-
18444395865
-
Neurons expressing relaxin 3/INSL 7 in the nucleus incertus respond to stress
-
Tanaka M., Iijima N., Miyamoto Y., Fukusumi S., Itoh Y., Ozawa H., Ibata Y. Neurons expressing relaxin 3/INSL 7 in the nucleus incertus respond to stress. Eur. J. Neurosci. 2005, 21:1659-1670.
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 1659-1670
-
-
Tanaka, M.1
Iijima, N.2
Miyamoto, Y.3
Fukusumi, S.4
Itoh, Y.5
Ozawa, H.6
Ibata, Y.7
-
176
-
-
65249190276
-
Relaxin for the treatment of patients with acute heart failure (pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study
-
Teerlink J.R., Metra M., Felker G.M., Ponikowski P., Voors A.A., Weatherley B.D., Marmor A., Katz A., Grzybowski J., Unemori E., Teichman S.L., Cotter G. Relaxin for the treatment of patients with acute heart failure (pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study. Lancet 2009, 373:1429-1439.
-
(2009)
Lancet
, vol.373
, pp. 1429-1439
-
-
Teerlink, J.R.1
Metra, M.2
Felker, G.M.3
Ponikowski, P.4
Voors, A.A.5
Weatherley, B.D.6
Marmor, A.7
Katz, A.8
Grzybowski, J.9
Unemori, E.10
Teichman, S.L.11
Cotter, G.12
-
177
-
-
70449113183
-
Relaxin, pleiotropic vasodilator for the treatment of heart failure
-
Teichman S.L., Unemori E., Dschietzig T., Conrad K., Voors A.A., Teerlink J.R., Felker G.M., Metra M., Cotter G. Relaxin, pleiotropic vasodilator for the treatment of heart failure. Heart Fail. Rev. 2009, 14:321-329.
-
(2009)
Heart Fail. Rev.
, vol.14
, pp. 321-329
-
-
Teichman, S.L.1
Unemori, E.2
Dschietzig, T.3
Conrad, K.4
Voors, A.A.5
Teerlink, J.R.6
Felker, G.M.7
Metra, M.8
Cotter, G.9
-
178
-
-
0033037935
-
Relaxin stimulates expression of vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women
-
Unemori E.N., Erikson M.E., Rocco S.E., Sutherland K.M., Parsell D.A., Mak J., Grove B.H. Relaxin stimulates expression of vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women. Hum. Reprod. 1999, 14:800-806.
-
(1999)
Hum. Reprod.
, vol.14
, pp. 800-806
-
-
Unemori, E.N.1
Erikson, M.E.2
Rocco, S.E.3
Sutherland, K.M.4
Parsell, D.A.5
Mak, J.6
Grove, B.H.7
-
179
-
-
34347338779
-
The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism
-
van der Westhuizen E.T., Werry T.D., Sexton P.M., Summers R.J. The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependent mechanism. Mol. Pharmacol. 2007, 71:1618-1629.
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 1618-1629
-
-
van der Westhuizen, E.T.1
Werry, T.D.2
Sexton, P.M.3
Summers, R.J.4
-
180
-
-
64549133824
-
A randomized, double-blind, placebo-controlled trial of relaxin for cervical ripening in post-delivery date pregnancies
-
Weiss G., Teichman S., Stewart D., Nader D., Wood S., Unemori E. A randomized, double-blind, placebo-controlled trial of relaxin for cervical ripening in post-delivery date pregnancies. Ann. N. Y. Acad. Sci. 2009, 1160:385-386.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 385-386
-
-
Weiss, G.1
Teichman, S.2
Stewart, D.3
Nader, D.4
Wood, S.5
Unemori, E.6
-
181
-
-
0032799753
-
Glycosylation of G-protein-coupled receptors for hormones central to normal reproductive functioning: its occurrence and role
-
Wheatley M., Hawtin S.R. Glycosylation of G-protein-coupled receptors for hormones central to normal reproductive functioning: its occurrence and role. Hum. Reprod. Update 1999, 5:356-364.
-
(1999)
Hum. Reprod. Update
, vol.5
, pp. 356-364
-
-
Wheatley, M.1
Hawtin, S.R.2
-
182
-
-
23644439429
-
Coevolution of the relaxin-like peptides and their receptors
-
Wilkinson T.N., Speed T.P., Tregear G.W., Bathgate R.A. Coevolution of the relaxin-like peptides and their receptors. Ann. N. Y. Acad. Sci. 2005, 1041:534-539.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1041
, pp. 534-539
-
-
Wilkinson, T.N.1
Speed, T.P.2
Tregear, G.W.3
Bathgate, R.A.4
-
183
-
-
15244345349
-
Evolution of the relaxin-like peptide family
-
Wilkinson T.N., Speed T.P., Tregear G.W., Bathgate R.A. Evolution of the relaxin-like peptide family. BMC Evol. Biol. 2005, 5:14.
-
(2005)
BMC Evol. Biol.
, vol.5
, pp. 14
-
-
Wilkinson, T.N.1
Speed, T.P.2
Tregear, G.W.3
Bathgate, R.A.4
-
184
-
-
33747614333
-
Expression of LGR7 and LGR8 by neonatal porcine uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by suckling
-
Yan W., Wiley A.A., Bathgate R.A., Frankshun A.L., Lasano S., Crean B.D., Steinetz B.G., Bagnell C.A., Bartol F.F. Expression of LGR7 and LGR8 by neonatal porcine uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by suckling. Endocrinology 2006, 147:4303-4310.
-
(2006)
Endocrinology
, vol.147
, pp. 4303-4310
-
-
Yan, W.1
Wiley, A.A.2
Bathgate, R.A.3
Frankshun, A.L.4
Lasano, S.5
Crean, B.D.6
Steinetz, B.G.7
Bagnell, C.A.8
Bartol, F.F.9
-
185
-
-
46049108362
-
Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function
-
Yan Y., Scott D.J., Wilkinson T.N., Ji J., Tregear G.W., Bathgate R.A. Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function. Biochemistry 2008, 47:6953-6968.
-
(2008)
Biochemistry
, vol.47
, pp. 6953-6968
-
-
Yan, Y.1
Scott, D.J.2
Wilkinson, T.N.3
Ji, J.4
Tregear, G.W.5
Bathgate, R.A.6
-
186
-
-
0026578887
-
Relaxin receptors in mice: demonstration of ligand binding in symphyseal tissues and uterine membrane fragments
-
Yang S., Rembiesa B., Bullesbach E.E., Schwabe C. Relaxin receptors in mice: demonstration of ligand binding in symphyseal tissues and uterine membrane fragments. Endocrinology 1992, 130:179-185.
-
(1992)
Endocrinology
, vol.130
, pp. 179-185
-
-
Yang, S.1
Rembiesa, B.2
Bullesbach, E.E.3
Schwabe, C.4
-
187
-
-
42449109125
-
Relaxin acts on stromal cells to promote epithelial and stromal proliferation and inhibit apoptosis in the mouse cervix and vagina
-
Yao L., Agoulnik A.I., Cooke P.S., Meling D.D., Sherwood O.D. Relaxin acts on stromal cells to promote epithelial and stromal proliferation and inhibit apoptosis in the mouse cervix and vagina. Endocrinology 2008, 149:2072-2079.
-
(2008)
Endocrinology
, vol.149
, pp. 2072-2079
-
-
Yao, L.1
Agoulnik, A.I.2
Cooke, P.S.3
Meling, D.D.4
Sherwood, O.D.5
-
188
-
-
64549111332
-
Relaxin family genes in humans and teleosts
-
Yegorov S., Good-Avila S.V., Parry L., Wilson B.C. Relaxin family genes in humans and teleosts. Ann. N. Y. Acad. Sci. 2009, 1160:42-44.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1160
, pp. 42-44
-
-
Yegorov, S.1
Good-Avila, S.V.2
Parry, L.3
Wilson, B.C.4
-
189
-
-
0036242761
-
Relaxin activates the MAP kinase pathway in human endometrial stromal cells
-
Zhang Q., Liu S.H., Erikson M., Lewis M., Unemori E. Relaxin activates the MAP kinase pathway in human endometrial stromal cells. J. Cell. Biochem. 2002, 85:536-544.
-
(2002)
J. Cell. Biochem.
, vol.85
, pp. 536-544
-
-
Zhang, Q.1
Liu, S.H.2
Erikson, M.3
Lewis, M.4
Unemori, E.5
-
190
-
-
0032918829
-
Mice without a functional relaxin gene are unable to deliver milk to their pups
-
Zhao L., Roche P.J., Gunnersen J.M., Hammond V.E., Tregear G.W., Wintour E.M., Beck F. Mice without a functional relaxin gene are unable to deliver milk to their pups. Endocrinology 1999, 140:445-453.
-
(1999)
Endocrinology
, vol.140
, pp. 445-453
-
-
Zhao, L.1
Roche, P.J.2
Gunnersen, J.M.3
Hammond, V.E.4
Tregear, G.W.5
Wintour, E.M.6
Beck, F.7
-
191
-
-
0033837983
-
Collagen studies in late pregnant relaxin null mice
-
Zhao L., Samuel C.S., Tregear G.W., Beck F., Wintour E.M. Collagen studies in late pregnant relaxin null mice. Biol. Reprod. 2000, 63:697-703.
-
(2000)
Biol. Reprod.
, vol.63
, pp. 697-703
-
-
Zhao, L.1
Samuel, C.S.2
Tregear, G.W.3
Beck, F.4
Wintour, E.M.5
-
192
-
-
0035017179
-
Evidence that relaxin inhibits apoptosis in the cervix and the vagina during the second half of pregnancy in the rat
-
Zhao S., Fields P.A., Sherwood O.D. Evidence that relaxin inhibits apoptosis in the cervix and the vagina during the second half of pregnancy in the rat. Endocrinology 2001, 142:2221-2229.
-
(2001)
Endocrinology
, vol.142
, pp. 2221-2229
-
-
Zhao, S.1
Fields, P.A.2
Sherwood, O.D.3
-
193
-
-
48049118575
-
Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135)
-
Zhu J., Kuei C., Sutton S., Kamme F., Yu J., Bonaventure P., Atack J., Lovenberg T.W., Liu C. Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135). Eur. J. Pharmacol. 2008, 590:43-52.
-
(2008)
Eur. J. Pharmacol.
, vol.590
, pp. 43-52
-
-
Zhu, J.1
Kuei, C.2
Sutton, S.3
Kamme, F.4
Yu, J.5
Bonaventure, P.6
Atack, J.7
Lovenberg, T.W.8
Liu, C.9
-
194
-
-
0033304740
-
Targeted disruption of the Insl3 gene causes bilateral cryptorchidism
-
Zimmermann S., Steding G., Emmen J.M., Brinkmann A., Nayernia K., Holstein A.F., Engel W., Adham I.M. Targeted disruption of the Insl3 gene causes bilateral cryptorchidism. Mol. Endocrinol. 1999, 13:681-691.
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 681-691
-
-
Zimmermann, S.1
Steding, G.2
Emmen, J.M.3
Brinkmann, A.4
Nayernia, K.5
Holstein, A.F.6
Engel, W.7
Adham, I.M.8
|