Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo

Journal of Biological Chemistry

Volumn 281, Issue 19, 2006, Pages 13068-13074

  Del Borgo, Mark P ^a   Hughes, Richard A ^a   Bathgate, Ross A D ^a   Lin, Feng ^a   Kawamura, Kazu ^b   Wade, John D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONFORMATIONS; INSULIN; SPECTROSCOPIC ANALYSIS; STRUCTURE (COMPOSITION); SYNTHESIS (CHEMICAL);

APOPTOSIS; CIRCULAR DICHROISM SPECTROSCOPY; INSULIN-LIKE PEPTIDE; MOLECULAR MODELING;

POLYPEPTIDES;

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; INSULIN; INSULIN LIKE PEPTIDE 3; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 7; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 8; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; INSULIN; MALE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; TESTIS;

EID: 33744955536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600472200     Document Type: Article

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