-
2
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature. 2001;410:1107-11.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
-
3
-
-
0035071525
-
NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma
-
Smyth MJ, Crowe NY, Godfrey DI. NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma. Int Immunol. 2001;13:459-63.
-
(2001)
Int Immunol
, vol.13
, pp. 459-463
-
-
Smyth, M.J.1
Crowe, N.Y.2
Godfrey, D.I.3
-
4
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll D. Does the immune system see tumors as foreign or self? Annu Rev Immunol. 2003;21:807-39.
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
5
-
-
4143141823
-
The immunobiology of cancer immunosurveillance and immunoediting
-
Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21:137-48.
-
(2004)
Immunity
, vol.21
, pp. 137-148
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
6
-
-
0034770605
-
Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells
-
Gorelik L, Flavell RA. Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells. Nat Med. 2001;7:1118-22.
-
(2001)
Nat Med
, vol.7
, pp. 1118-1122
-
-
Gorelik, L.1
Flavell, R.A.2
-
7
-
-
0031296663
-
TCR vaccines for active immunotherapy of T cell malignancies
-
Okada CY, Wong CP, Denney DW, Levy R. TCR vaccines for active immunotherapy of T cell malignancies. J Immunol. 1997;159:5516-27.
-
(1997)
J Immunol
, vol.159
, pp. 5516-5527
-
-
Okada, C.Y.1
Wong, C.P.2
Denney, D.W.3
Levy, R.4
-
8
-
-
0034695880
-
Differential tumor surveillance by natural killer (NK) and NKT cells
-
Smyth MJ, Thia KY, Street SE, Cretney E, Trapani JA, Taniguchi M, et al. Differential tumor surveillance by natural killer (NK) and NKT cells. J Exp Med. 2000;191:661-8.
-
(2000)
J Exp Med
, vol.191
, pp. 661-668
-
-
Smyth, M.J.1
Thia, K.Y.2
Street, S.E.3
Cretney, E.4
Trapani, J.A.5
Taniguchi, M.6
-
9
-
-
0035914134
-
Regulation of cutaneous malignancy by gammadelta T cells
-
Girardi M, Oppenheim DE, Steele CR, Lewis JM, Glusac E, Filler R, et al. Regulation of cutaneous malignancy by gammadelta T cells. Science. 2001;294:605-9.
-
(2001)
Science
, vol.294
, pp. 605-609
-
-
Girardi, M.1
Oppenheim, D.E.2
Steele, C.R.3
Lewis, J.M.4
Glusac, E.5
Filler, R.6
-
10
-
-
0034646255
-
In vivo natural killer cell activities revealed by natural killer cell-deficient mice
-
Kim S, Iizuka K, Aguila HL, Weissman IL, Yokoyama WM. In vivo natural killer cell activities revealed by natural killer cell-deficient mice. Proc Natl Acad Sci USA. 2000;97:2731-6.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2731-2736
-
-
Kim, S.1
Iizuka, K.2
Aguila, H.L.3
Weissman, I.L.4
Yokoyama, W.M.5
-
11
-
-
22144465860
-
A critical function for type I interferons in cancer immunoediting
-
Dunn GP, Bruce AT, Sheehan KC, Shankaran V, Uppaluri R, Bui JD, et al. A critical function for type I interferons in cancer immunoediting. Nat Immunol. 2005;6:722-9.
-
(2005)
Nat Immunol
, vol.6
, pp. 722-729
-
-
Dunn, G.P.1
Bruce, A.T.2
Sheehan, K.C.3
Shankaran, V.4
Uppaluri, R.5
Bui, J.D.6
-
12
-
-
0038725690
-
The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal
-
Lieberman J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nat Rev Immunol. 2003;3:361-70.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 361-370
-
-
Lieberman, J.1
-
13
-
-
0036217977
-
Lymphocyte-mediated cytotoxicity
-
Russell JH, Ley TJ. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol. 2002;20:323-70.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 323-370
-
-
Russell, J.H.1
Ley, T.J.2
-
16
-
-
0033991158
-
Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
-
Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol. 2000;74:181-273.
-
(2000)
Adv Immunol
, vol.74
, pp. 181-273
-
-
Marincola, F.M.1
Jaffee, E.M.2
Hicklin, D.J.3
Ferrone, S.4
-
17
-
-
0033827817
-
Antigen-processing machinery breakdown and tumor growth
-
Seliger B, Maeurer MJ, Ferrone S. Antigen-processing machinery breakdown and tumor growth. Immunol Today. 2000;21:455-64.
-
(2000)
Immunol Today
, vol.21
, pp. 455-464
-
-
Seliger, B.1
Maeurer, M.J.2
Ferrone, S.3
-
18
-
-
0032101973
-
Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL
-
Bakker AB, Phillips JH, Figdor CG, Lanier LL. Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL. J Immunol. 1998;160:5239-45.
-
(1998)
J Immunol
, vol.160
, pp. 5239-5245
-
-
Bakker, A.B.1
Phillips, J.H.2
Figdor, C.G.3
Lanier, L.L.4
-
19
-
-
0031053587
-
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes
-
Moretta A, Biassoni R, Bottino C, Pende D, Vitale M, Poggi A, et al. Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunol Rev. 1997;155:105-17.
-
(1997)
Immunol Rev
, vol.155
, pp. 105-117
-
-
Moretta, A.1
Biassoni, R.2
Bottino, C.3
Pende, D.4
Vitale, M.5
Poggi, A.6
-
20
-
-
0030042385
-
Inhibitory MHC class I receptors on NK cells and T cells
-
Lanier LL, Phillips JH. Inhibitory MHC class I receptors on NK cells and T cells. Immunol Today. 1996;17:86-91.
-
(1996)
Immunol Today
, vol.17
, pp. 86-91
-
-
Lanier, L.L.1
Phillips, J.H.2
-
21
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
22
-
-
2442484053
-
+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol. 2004;22:531-62.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
23
-
-
31644432589
-
Regulatory T cells in immune surveillance and treatment of cancer
-
Yamaguchi T, Sakaguchi S. Regulatory T cells in immune surveillance and treatment of cancer. Semin Cancer Biol. 2006;16:115-23.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 115-123
-
-
Yamaguchi, T.1
Sakaguchi, S.2
-
25
-
-
33645286546
-
T cells, tumour immunity and immunotherapy
-
Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol. 2006;6:295-307.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 295-307
-
-
Regulatory, Z.W.1
-
26
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol. 2005;6:338-44.
-
(2005)
Nat Immunol
, vol.6
, pp. 338-344
-
-
von Boehmer, H.1
-
27
-
-
5144228905
-
+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer
-
+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer. Exp Dermatol. 2004;13:613-20.
-
(2004)
Exp Dermatol
, vol.13
, pp. 613-620
-
-
Nagai, H.1
Horikawa, T.2
Hara, I.3
Fukunaga, A.4
Oniki, S.5
Oka, M.6
-
28
-
-
0033168037
-
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
-
Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, Nakayama E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 1999;9:3128-33.
-
(1999)
Cancer Res
, vol.9
, pp. 3128-3133
-
-
Onizuka, S.1
Tawara, I.2
Shimizu, J.3
Sakaguchi, S.4
Fujita, T.5
Nakayama, E.6
-
29
-
-
0033571105
-
+ T cells: A common basis between tumor immunity and autoimmunity
-
+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol. 1999;163:5211-8.
-
(1999)
J Immunol
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
30
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Sakaguchi S, Houghton AN. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med. 2004;200:771-82.
-
(2004)
J Exp Med
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
Guevara-Patino, J.A.2
Rizzuto, G.A.3
Engelhorn, M.E.4
Sakaguchi, S.5
Houghton, A.N.6
-
33
-
-
34248194231
-
Tregs and rethinking cancer immunotherapy
-
Curiel TJ. Tregs and rethinking cancer immunotherapy. J Clin Invest. 2007;117:1167-74.
-
(2007)
J Clin Invest
, vol.117
, pp. 1167-1174
-
-
Curiel, T.J.1
-
34
-
-
0014667395
-
Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
-
Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science. 1969;166:753-5.
-
(1969)
Science
, vol.166
, pp. 753-755
-
-
Nishizuka, Y.1
Sakakura, T.2
-
35
-
-
0020451946
-
Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
-
Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J Exp Med. 1982;156:1577-86.
-
(1982)
J Exp Med
, vol.156
, pp. 1577-1586
-
-
Sakaguchi, S.1
Takahashi, T.2
Nishizuka, Y.3
-
37
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri E, Torgerson TR, Ochs HD. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol. 2003;15:430-5.
-
(2003)
Curr Opin Rheumatol
, vol.15
, pp. 430-435
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
38
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet. 2001;27:68-73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
-
42
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med. 2004;199:1401-8.
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
von Boehmer, H.2
-
45
-
-
0037128654
-
Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells
-
Gilliet M, Liu YJ. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med. 2002;195:695-704.
-
(2002)
J Exp Med
, vol.195
, pp. 695-704
-
-
Gilliet, M.1
Liu, Y.J.2
-
47
-
-
33847370194
-
Regulatory T cells dynamically control the primary immune response to foreign antigen
-
Haribhai D, Lin W, Relland LM, Truong N, Williams CB, Chatila TA. Regulatory T cells dynamically control the primary immune response to foreign antigen. J Immunol. 2007;178:2961-72.
-
(2007)
J Immunol
, vol.178
, pp. 2961-2972
-
-
Haribhai, D.1
Lin, W.2
Relland, L.M.3
Truong, N.4
Williams, C.B.5
Chatila, T.A.6
-
48
-
-
23844459503
-
Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation of recipient double-negative regulatory T cells
-
Chen W, Zhou D, Torrealba JR, Waddell TK, Grant D, Zhang L. Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation of recipient double-negative regulatory T cells. J Immunol. 2005;175:3409-16.
-
(2005)
J Immunol
, vol.175
, pp. 3409-3416
-
-
Chen, W.1
Zhou, D.2
Torrealba, J.R.3
Waddell, T.K.4
Grant, D.5
Zhang, L.6
-
50
-
-
34548024379
-
Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway
-
Peng G, Wang HY, Peng W, Kiniwa Y, Seo KH, Wang RF. Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity. 2007;27:334-48.
-
(2007)
Immunity
, vol.27
, pp. 334-348
-
-
Peng, G.1
Wang, H.Y.2
Peng, W.3
Kiniwa, Y.4
Seo, K.H.5
Wang, R.F.6
-
51
-
-
34548042986
-
The expanding universe of regulatory T cell subsets in cancer
-
Gajewski TF. The expanding universe of regulatory T cell subsets in cancer. Immunity. 2007;27:185-7.
-
(2007)
Immunity
, vol.27
, pp. 185-187
-
-
Gajewski, T.F.1
-
52
-
-
0027521572
-
Interleukin-10- deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10- deficient mice develop chronic enterocolitis. Cell. 1993;75:263-74.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
53
-
-
0027531528
-
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders KC, et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA. 1993;90:770-4.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
Huh, C.G.2
Becker, D.3
Geiser, A.4
Lyght, M.5
Flanders, K.C.6
-
56
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med. 2002;8:1024-32.
-
(2002)
Nat Med
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
Freeman, G.J.2
Meyer, E.H.3
Greenfield, E.A.4
Chang, T.T.5
Sharpe, A.H.6
-
57
-
-
3242754344
-
Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3
-
Ostroukhova M, Seguin-Devaux C, Oriss TB, Dixon-McCarthy B, Yang L, Ameredes BT, et al. Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J Clin Invest. 2004;114:28-38.
-
(2004)
J Clin Invest
, vol.114
, pp. 28-38
-
-
Ostroukhova, M.1
Seguin-Devaux, C.2
Oriss, T.B.3
Dixon-McCarthy, B.4
Yang, L.5
Ameredes, B.T.6
-
58
-
-
68549110270
-
The development and function of regulatory T cells
-
Workman CJ, Szymczak-Workman AL, Collison LW, Pillai MR, Vignali DA. The development and function of regulatory T cells. Cell Mol Life Sci. 2009;66:2603-22.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2603-2622
-
-
Workman, C.J.1
Szymczak-Workman, A.L.2
Collison, L.W.3
Pillai, M.R.4
Vignali, D.A.5
-
59
-
-
34547204632
-
Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment
-
You S, Leforban B, Garcia C, Bach JF, Bluestone JA, Chatenoud L. Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment. Proc Natl Acad Sci USA. 2007;104:6335-40.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6335-6340
-
-
You, S.1
Leforban, B.2
Garcia, C.3
Bach, J.F.4
Bluestone, J.A.5
Chatenoud, L.6
-
60
-
-
57749170446
-
Immunoregulatory pathways controlling progression of autoimmunity in NOD mice
-
You S, Alyanakian MA, Segovia B, Damotte D, Bluestone J, Bach JF, et al. Immunoregulatory pathways controlling progression of autoimmunity in NOD mice. Ann NY Acad Sci. 2008;1150:300-10.
-
(2008)
Ann NY Acad Sci
, vol.1150
, pp. 300-310
-
-
You, S.1
Alyanakian, M.A.2
Segovia, B.3
Damotte, D.4
Bluestone, J.5
Bach, J.F.6
-
61
-
-
34250813631
-
IL-10 controls ultravioletinduced carcinogenesis in mice
-
Loser K, Apelt J, Voskort M, Mohaupt M, Balkow S, Schwarz T, et al. IL-10 controls ultravioletinduced carcinogenesis in mice. J Immunol. 2007;179:365-71.
-
(2007)
J Immunol
, vol.179
, pp. 365-371
-
-
Loser, K.1
Apelt, J.2
Voskort, M.3
Mohaupt, M.4
Balkow, S.5
Schwarz, T.6
-
62
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, et al. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci USA. 2005;102:419-24.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 419-424
-
-
Chen, M.L.1
Pittet, M.J.2
Gorelik, L.3
Flavell, R.A.4
Weissleder, R.5
von Boehmer, H.6
-
63
-
-
47949104587
-
In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1
-
Gil-Guerrero L, Dotor J, Huibregtse IL, Casares N, Lopez-Vazquez AB, Rudilla F, et al. In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1. J Immunol. 2008;181:126-35.
-
(2008)
J Immunol
, vol.181
, pp. 126-135
-
-
Gil-Guerrero, L.1
Dotor, J.2
Huibregtse, I.L.3
Casares, N.4
Lopez-Vazquez, A.B.5
Rudilla, F.6
-
65
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature. 2007;450:566-9.
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
Boyd, K.4
Wang, Y.5
Vignali, K.M.6
-
67
-
-
0034605122
-
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
-
Smyth MJ, Thia KY, Street SE, MacGregor D, Godfrey DI, Trapani JA. Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med. 2000;192:755-60.
-
(2000)
J Exp Med
, vol.192
, pp. 755-760
-
-
Smyth, M.J.1
Thia, K.Y.2
Street, S.E.3
MacGregor, D.4
Godfrey, D.I.5
Trapani, J.A.6
-
68
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity. 2004;21:589-601.
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
70
-
-
33646567156
-
Activated CD4?CD25? T cells selectively kill B lymphocytes
-
Zhao DM, Thornton AM, DiPaolo RJ, Shevach EM. Activated CD4?CD25? T cells selectively kill B lymphocytes. Blood. 2006;107:3925-32.
-
(2006)
Blood
, vol.107
, pp. 3925-3932
-
-
Zhao, D.M.1
Thornton, A.M.2
DiPaolo, R.J.3
Shevach, E.M.4
-
71
-
-
35449006679
-
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
-
Cao X, Cai SF, Fehniger TA, Song J, Collins LI, Piwnica-Worms DR, et al. Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. Immunity. 2007;27:635-46.
-
(2007)
Immunity
, vol.27
, pp. 635-646
-
-
Cao, X.1
Cai, S.F.2
Fehniger, T.A.3
Song, J.4
Collins, L.I.5
Piwnica-Worms, D.R.6
-
72
-
-
58149290252
-
Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells
-
Gondek DC, Devries V, Nowak EC, Lu LF, Bennett KA, Scott ZA, et al. Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells. J Immunol. 2008;181:4752-60.
-
(2008)
J Immunol
, vol.181
, pp. 4752-4760
-
-
Gondek, D.C.1
Devries, V.2
Nowak, E.C.3
Lu, L.F.4
Bennett, K.A.5
Scott, Z.A.6
-
74
-
-
36248995916
-
Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells
-
Ren X, Ye F, Jiang Z, Chu Y, Xiong S, Wang Y. Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells. Cell Death Differ. 2007;14:2076-84.
-
(2007)
Cell Death Differ
, vol.14
, pp. 2076-2084
-
-
Ren, X.1
Ye, F.2
Jiang, Z.3
Chu, Y.4
Xiong, S.5
Wang, Y.6
-
75
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, Serra P, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol. 2006;7:83-92.
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
Serra, P.6
-
76
-
-
33645067654
-
Regulatory T cells inhibit stable contacts between CD4? T cells and dendritic cells in vivo
-
Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, Maraver A, et al. Regulatory T cells inhibit stable contacts between CD4? T cells and dendritic cells in vivo. J Exp Med. 2006;203:505-11.
-
(2006)
J Exp Med
, vol.203
, pp. 505-511
-
-
Tadokoro, C.E.1
Shakhar, G.2
Shen, S.3
Ding, Y.4
Lino, A.C.5
Maraver, A.6
-
77
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med. 2000;192:295-302.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
80
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol. 2004;4:762-74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
81
-
-
0033519278
-
Inhibition of T cell proliferation by macrophage tryptophan catabolism
-
Munn DH, Shafizadeh E, Attwood JT, Bondarev I, Pashine A, Mellor AL. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med. 1999;189:1363-72.
-
(1999)
J Exp Med
, vol.189
, pp. 1363-1372
-
-
Munn, D.H.1
Shafizadeh, E.2
Attwood, J.T.3
Bondarev, I.4
Pashine, A.5
Mellor, A.L.6
-
82
-
-
0036790338
-
T cell apoptosis by tryptophan catabolism
-
Fallarino F, Grohmann U, Vacca C, Bianchi R, Orabona C, Spreca A, et al. T cell apoptosis by tryptophan catabolism. Cell Death Differ. 2002;9:1069-77.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1069-1077
-
-
Fallarino, F.1
Grohmann, U.2
Vacca, C.3
Bianchi, R.4
Orabona, C.5
Spreca, A.6
-
83
-
-
34848915783
-
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase
-
Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, et al. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase. J Clin Invest. 2007;117:2570-82.
-
(2007)
J Clin Invest
, vol.117
, pp. 2570-2582
-
-
Sharma, M.D.1
Baban, B.2
Chandler, P.3
Hou, D.Y.4
Singh, N.5
Yagita, H.6
-
85
-
-
34250376423
-
Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression
-
Bopp T, Becker C, Klein M, Klein-Hessling S, Palmetshofer A, Serfling E, et al. Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. J Exp Med. 2007;204:1303-10.
-
(2007)
J Exp Med
, vol.204
, pp. 1303-1310
-
-
Bopp, T.1
Becker, C.2
Klein, M.3
Klein-Hessling, S.4
Palmetshofer, A.5
Serfling, E.6
-
87
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
-
91
-
-
62449250053
-
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
-
Gobert M, Treilleux I, Bendriss-Vermare N, Bachelot T, Goddard-Leon S, Arfi V, et al. Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res. 2009;69:2000-9.
-
(2009)
Cancer Res
, vol.69
, pp. 2000-2009
-
-
Gobert, M.1
Treilleux, I.2
Bendriss-Vermare, N.3
Bachelot, T.4
Goddard-Leon, S.5
Arfi, V.6
-
92
-
-
30444443314
-
Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
-
Zhou G, Drake CG, Levitsky HI. Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood. 2006;107:628-36.
-
(2006)
Blood
, vol.107
, pp. 628-636
-
-
Zhou, G.1
Drake, C.G.2
Levitsky, H.I.3
-
93
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
-
Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol. 2006;7:401-10.
-
(2006)
Nat Immunol
, vol.7
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
95
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, et al. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med. 2004;199:1455-65.
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
-
96
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel E, von Boehmer H, Manns MP. Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes. 2005;54:306-10.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
von Boehmer, H.2
Manns, M.P.3
-
99
-
-
37849009964
-
A two-step process for thymic regulatory T cell development
-
Lio CW, Hsieh CS. A two-step process for thymic regulatory T cell development. Immunity. 2008;28:100-11.
-
(2008)
Immunity
, vol.28
, pp. 100-111
-
-
Lio, C.W.1
Hsieh, C.S.2
-
100
-
-
37849008688
-
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
-
Burchill MA, Yang J, Vang KB, Moon JJ, Chu HH, Lio CW, et al. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity. 2008;28:112-21.
-
(2008)
Immunity
, vol.28
, pp. 112-121
-
-
Burchill, M.A.1
Yang, J.2
Vang, K.B.3
Moon, J.J.4
Chu, H.H.5
Lio, C.W.6
-
103
-
-
55349100505
-
Optimizing denileukin diftitox (Ontak) therapy
-
Duvic M, Talpur R. Optimizing denileukin diftitox (Ontak) therapy. Future Oncol. 2008;4:457-69.
-
(2008)
Future Oncol
, vol.4
, pp. 457-469
-
-
Duvic, M.1
Talpur, R.2
-
104
-
-
30144444279
-
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
-
Dannull J, Su Z, Rizzieri D, Yang BK, Coleman D, Yancey D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest. 2005;115:3623-33.
-
(2005)
J Clin Invest
, vol.115
, pp. 3623-3633
-
-
Dannull, J.1
Su, Z.2
Rizzieri, D.3
Yang, B.K.4
Coleman, D.5
Yancey, D.6
-
105
-
-
58749105795
-
Overcoming immunologic tolerance to melanoma: Targeting CTLA-4 with ipilimumab (MDX-010)
-
Weber J. Overcoming immunologic tolerance to melanoma: targeting CTLA-4 with ipilimumab (MDX-010). Oncologist. 2008;13(Suppl 4):16-25.
-
(2008)
Oncologist
, vol.13
, Issue.SUPPL. 4
, pp. 16-25
-
-
Weber, J.1
-
106
-
-
39449126502
-
The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
-
Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol. 2008;9:239-44.
-
(2008)
Nat Immunol
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
|