Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

Journal of Clinical Investigation

Volumn 115, Issue 12, 2005, Pages 3623-3633

  Dannull, Jens ^a   Su, Zhen ^a   Rizzieri, David ^a   Yang, Benjamin K ^a   Coleman, Doris ^a   Yancey, Donna ^a   Zhang, Aijing ^a   Dahm, Philipp ^a   Chao, Nelson ^a   Gilboa, Eli ^a   Vieweg, Johannes ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; DENDRITIC CELL VACCINE; DENILEUKIN DIFTITOX; INTERLEUKIN 2 RECEPTOR ALPHA; RNA;

ADULT; AGED; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PATIENT; CELL POPULATION; CELL PROLIFERATION; CELL STIMULATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG POTENCY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY CARCINOMA; MALE; METASTASIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; STATISTICAL SIGNIFICANCE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY;

AGED; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, NEOPLASM; CANCER VACCINES; CARCINOMA, RENAL CELL; CD4-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; DENDRITIC CELLS; DIPHTHERIA TOXIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; KIDNEY NEOPLASMS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASMS; RECEPTORS, INTERLEUKIN-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, NEOPLASM; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TIME FACTORS; TRANSFECTION;

EID: 30144444279     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI25947     Document Type: Article

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