-
1
-
-
0033695810
-
Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes
-
Bandyopadhyay G, Kanoh Y, Sajan MP, Standaert ML, Farese RV. Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes. Endocrinology 141: 4120-4127, 2000.
-
(2000)
Endocrinology
, vol.141
, pp. 4120-4127
-
-
Bandyopadhyay, G.1
Kanoh, Y.2
Sajan, M.P.3
Standaert, M.L.4
Farese, R.V.5
-
2
-
-
0036173994
-
PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes
-
Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Lea-Currie R, Sen A, Farese RV. PKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytes. J Clin Endocrinol Metab 87: 716-723, 2002.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 716-723
-
-
Bandyopadhyay, G.1
Sajan, M.P.2
Kanoh, Y.3
Standaert, M.L.4
Quon, M.J.5
Lea-Currie, R.6
Sen, A.7
Farese, R.V.8
-
3
-
-
0030812546
-
Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes
-
Bandyopadhyay G, Standaert ML, Galloway L, Moscat J, Farese RV. Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 138: 4721-4731, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 4721-4731
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Galloway, L.3
Moscat, J.4
Farese, R.V.5
-
4
-
-
0033082749
-
Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ε) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes. Specific interchangeable effects of protein kinase C-ζ and -λ
-
Bandyopadhyay G, Standaert ML, Kikkawa U, Ono Y, Moscat J, Farese RV. Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ε) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes. Specific interchangeable effects of protein kinase C-ζ and -λ. Biochem J 337: 461-470, 1999.
-
(1999)
Biochem J
, vol.337
, pp. 461-470
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Kikkawa, U.3
Ono, Y.4
Moscat, J.5
Farese, R.V.6
-
5
-
-
0031038052
-
Activation of PKC (α, β, and ζ) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-ζ in glucose transport
-
Bandyopadhyay G, Standaert ML, Zhao L, Yu B, Avignon A, Galloway L, Karnam P, Moscat J, Farese RV. Activation of PKC (α, β, and ζ) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-ζ in glucose transport. J Biol Chem 272: 2551-2558, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 2551-2558
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Zhao, L.3
Yu, B.4
Avignon, A.5
Galloway, L.6
Karnam, P.7
Moscat, J.8
Farese, R.V.9
-
6
-
-
23644448924
-
Increased p85/55/50 expression and decreased phosphatidylinositol 3-kinase activity in insulin-resistant skeletal muscle
-
Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM. Increased p85/55/50 expression and decreased phosphatidylinositol 3-kinase activity in insulin-resistant skeletal muscle. Diabetes 54: 2351-2359, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 2351-2359
-
-
Bandyopadhyay, G.K.1
Yu, J.G.2
Ofrecio, J.3
Olefsky, J.M.4
-
7
-
-
0042093782
-
-
3 is defective in muscle in type 2 diabetes and impaired glucose intolerance. Amelioration by rosiglitazone and exercise. Diabetes 52: 1926-1934, 2003.
-
3 is defective in muscle in type 2 diabetes and impaired glucose intolerance. Amelioration by rosiglitazone and exercise. Diabetes 52: 1926-1934, 2003.
-
-
-
-
8
-
-
5044250556
-
-
3 in obesity and polycystic ovary syndrome. Metabolic Syndr Relat Disord 2: 49-56, 2004.
-
3 in obesity and polycystic ovary syndrome. Metabolic Syndr Relat Disord 2: 49-56, 2004.
-
-
-
-
9
-
-
13444259991
-
Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells
-
Bicaku E, Patel R, Acevedo-Duncan M. Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells. Tissue Cell 37: 53-58, 2005.
-
(2005)
Tissue Cell
, vol.37
, pp. 53-58
-
-
Bicaku, E.1
Patel, R.2
Acevedo-Duncan, M.3
-
10
-
-
0034774069
-
Activation of protein kinase C zeta induces serine phpsphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle
-
Braiman L, Alt A, Kuroki T, Ohba M, Bak A, Tennenbaum T, Sampson SR. Activation of protein kinase C zeta induces serine phpsphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle. Mol Cell Biol 21: 7852-7861, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7852-7861
-
-
Braiman, L.1
Alt, A.2
Kuroki, T.3
Ohba, M.4
Bak, A.5
Tennenbaum, T.6
Sampson, S.R.7
-
11
-
-
0035489990
-
Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation
-
Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M. Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes 50: 2237-2243, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 2237-2243
-
-
Buteau, J.1
Foisy, S.2
Rhodes, C.J.3
Carpenter, L.4
Biden, T.J.5
Prentki, M.6
-
12
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11: 183-190, 2005.
-
(2005)
Nat Med
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
13
-
-
0037189548
-
Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport
-
Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, Farese RV Jr, Farese RV. Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport. J Biol Chem 277: 23554-23562, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 23554-23562
-
-
Chen, H.C.1
Bandyopadhyay, G.2
Sajan, M.P.3
Kanoh, Y.4
Standaert, M.5
Farese Jr, R.V.6
Farese, R.V.7
-
14
-
-
0042525909
-
Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation
-
Duran A, Diaz-Meco MT, Moscat J. Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation. EMBO J 22: 3910-3918, 2003.
-
(2003)
EMBO J
, vol.22
, pp. 3910-3918
-
-
Duran, A.1
Diaz-Meco, M.T.2
Moscat, J.3
-
15
-
-
34547663520
-
Muscle-specific knockout of protein kinase C-λ impairs glucose transport and induces metabolic and diabetic syndromes
-
Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WJ Jr, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M. Muscle-specific knockout of protein kinase C-λ impairs glucose transport and induces metabolic and diabetic syndromes. J Clin Invest 117: 2289-2301, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 2289-2301
-
-
Farese, R.V.1
Sajan, M.P.2
Yang, H.3
Li, P.4
Mastorides, S.5
Gower Jr, W.J.6
Nimal, S.7
Choi, C.S.8
Kim, S.9
Shulman, G.I.10
Kahn, C.R.11
Braun, U.12
Leitges, M.13
-
16
-
-
36749037936
-
Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer
-
Fields AP, Frederick LA, Regala RP. Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer. Biochem Soc Trans 35: 996-1000, 2007.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 996-1000
-
-
Fields, A.P.1
Frederick, L.A.2
Regala, R.P.3
-
17
-
-
3342977753
-
Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells
-
Guizzetti M, Thompson BD, Kim Y, VanDeMark K, Costa LG. Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells. J Neurochem 90: 646-653, 2004.
-
(2004)
J Neurochem
, vol.90
, pp. 646-653
-
-
Guizzetti, M.1
Thompson, B.D.2
Kim, Y.3
VanDeMark, K.4
Costa, L.G.5
-
18
-
-
67650032833
-
α1-AMPK-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase Cζ
-
Gusarova GA, Dada LA, Kelly AM, Brodie C, Witters LE, Chandel NS, Sznajder JI. α1-AMPK-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase Cζ. Mol Cell Biol 29: 3455-3464, 2009.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3455-3464
-
-
Gusarova, G.A.1
Dada, L.A.2
Kelly, A.M.3
Brodie, C.4
Witters, L.E.5
Chandel, N.S.6
Sznajder, J.I.7
-
19
-
-
85047693987
-
PKClambda regulates glucoseinduced insulin secretion through modulation of gene expression in pancreatic islets
-
Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M. PKClambda regulates glucoseinduced insulin secretion through modulation of gene expression in pancreatic islets. J Clin Invest 115: 138-145, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 138-145
-
-
Hashimoto, N.1
Kido, Y.2
Uchida, T.3
Matsuda, T.4
Suzuki, K.5
Inoue, H.6
Matsumoto, M.7
Ogawa, W.8
Maeda, S.9
Fujihara, H.10
Ueta, Y.11
Uchiyama, Y.12
Akimoto, K.13
Ohno, S.14
Noda, T.15
Kasuga, M.16
-
20
-
-
0642376906
-
Protein kinase Czeta (PKCzeta): Activation mechanisms and cellular functions
-
Hirai T, Chida K. Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions. J Biochem 133: 1-7, 2003.
-
(2003)
J Biochem
, vol.133
, pp. 1-7
-
-
Hirai, T.1
Chida, K.2
-
21
-
-
3843129678
-
Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5
-
Hirano Y, Yoshinaga S, Ogura K, Yokochi M, Noda Y, Sumimoto H, Inagaki F. Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5. J Biol Chem 279: 31883-31890, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 31883-31890
-
-
Hirano, Y.1
Yoshinaga, S.2
Ogura, K.3
Yokochi, M.4
Noda, Y.5
Sumimoto, H.6
Inagaki, F.7
-
22
-
-
0042093781
-
Insulinstimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: Reversal with weight reduction
-
Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB. Insulinstimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction. Diabetes 52: 1935-1942, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 1935-1942
-
-
Kim, Y.B.1
Kotani, K.2
Ciaraldi, T.P.3
Henry, R.R.4
Kahn, B.B.5
-
23
-
-
0031724590
-
Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes
-
Kotani K, Ogawa W, Matsumoto M, Kitamura T, Sakaue H, Hino Y, Miyake K, Sano W, Akimoto K, Ohno S, Kasuga M. Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes. Mol Cell Biol 18: 6971-6982, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6971-6982
-
-
Kotani, K.1
Ogawa, W.2
Matsumoto, M.3
Kitamura, T.4
Sakaue, H.5
Hino, Y.6
Miyake, K.7
Sano, W.8
Akimoto, K.9
Ohno, S.10
Kasuga, M.11
-
24
-
-
0032588389
-
Activation of IkappaB kinase beta by protein kinase C isoforms
-
Lallena MJ, Diaz-Meco MT, Bren G, Payá CV, Moscat J. Activation of IkappaB kinase beta by protein kinase C isoforms. Mol Cell Biol 19: 2180-2188, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2180-2188
-
-
Lallena, M.J.1
Diaz-Meco, M.T.2
Bren, G.3
Payá, C.V.4
Moscat, J.5
-
25
-
-
0032566691
-
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
-
Le Good JA, Ziegler WH, Parekh DB, Alessi DR, Cohen P, Parker PJ. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science 281: 2042-2045, 1998.
-
(1998)
Science
, vol.281
, pp. 2042-2045
-
-
Le Good, J.A.1
Ziegler, W.H.2
Parekh, D.B.3
Alessi, D.R.4
Cohen, P.5
Parker, P.J.6
-
26
-
-
0242713738
-
Knockout of protein kinase C-α enhances insulin signaling through phosphatidylinositol 3-kinase
-
Leitges M, Ploman M, Standaert ML, Bandyopadhyay G, Sajan MP, Kanoh Y, Farese RV. Knockout of protein kinase C-α enhances insulin signaling through phosphatidylinositol 3-kinase. Mol Endocrinol 16: 847-858, 2002.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 847-858
-
-
Leitges, M.1
Ploman, M.2
Standaert, M.L.3
Bandyopadhyay, G.4
Sajan, M.P.5
Kanoh, Y.6
Farese, R.V.7
-
27
-
-
33745746346
-
Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells
-
Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y, Fang FD, Tong PC. Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells. Mol Biol Cell 17: 2322-2330, 2006.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 2322-2330
-
-
Liu, L.Z.1
Zhao, H.L.2
Zuo, J.3
Ho, S.K.4
Chan, J.C.5
Meng, Y.6
Fang, F.D.7
Tong, P.C.8
-
28
-
-
31844437335
-
-
3 in muscle of diabetic subjects. Diabetologia 49: 375-382, 2006.
-
3 in muscle of diabetic subjects. Diabetologia 49: 375-382, 2006.
-
-
-
-
29
-
-
51649083258
-
Phosphorylation of the human full-length protein kinase Ciota
-
Macek B, Benda C, Jestel A, Maskos K, Mann M, Messerschmidt A. Phosphorylation of the human full-length protein kinase Ciota. J Proteome Res 7: 2928-2935, 2008.
-
(2008)
J Proteome Res
, vol.7
, pp. 2928-2935
-
-
Macek, B.1
Benda, C.2
Jestel, A.3
Maskos, K.4
Mann, M.5
Messerschmidt, A.6
-
30
-
-
0142217895
-
PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
-
Matsumoto M, Ogawa W, Akimoto K, Inoue H, Miyaki K, Furukawa K, Hayashi Y, Iguchi H, Marsuki Y, Hiramatsu R, Shimano H, Yamada N, Ohno S, Kasuga M, Noda T. PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. J Clin Invest 112: 935-944, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 935-944
-
-
Matsumoto, M.1
Ogawa, W.2
Akimoto, K.3
Inoue, H.4
Miyaki, K.5
Furukawa, K.6
Hayashi, Y.7
Iguchi, H.8
Marsuki, Y.9
Hiramatsu, R.10
Shimano, H.11
Yamada, N.12
Ohno, S.13
Kasuga, M.14
Noda, T.15
-
31
-
-
24644488646
-
Crystal structure of the catalytic domain of human atypical protein kinase C-iota reveals interaction mode of phosphorylation site in turn motif
-
Messerschmidt A, Macieira S, Velarde M, Bädeker M, Benda C, Jestel A, Brandstetter H, Neuefeind T, Blaesse M. Crystal structure of the catalytic domain of human atypical protein kinase C-iota reveals interaction mode of phosphorylation site in turn motif. J Mol Biol 30: 918-931, 2005.
-
(2005)
J Mol Biol
, vol.30
, pp. 918-931
-
-
Messerschmidt, A.1
Macieira, S.2
Velarde, M.3
Bädeker, M.4
Benda, C.5
Jestel, A.6
Brandstetter, H.7
Neuefeind, T.8
Blaesse, M.9
-
32
-
-
10644251864
-
Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes
-
Miura A, Sajan MP, Standaert ML, Bandyopadhyay G, Kahn CR, Farese RV. Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes. Biochemistry 43: 15503-15509, 2004.
-
(2004)
Biochemistry
, vol.43
, pp. 15503-15509
-
-
Miura, A.1
Sajan, M.P.2
Standaert, M.L.3
Bandyopadhyay, G.4
Kahn, C.R.5
Farese, R.V.6
-
33
-
-
38349124747
-
Involvement of PKC-iota in glioma proliferation
-
Patel R, Win H, Desai S, Patel K, Matthews JA, Acevedo-Duncan M. Involvement of PKC-iota in glioma proliferation. Cell Prolif 41: 122-135, 2008.
-
(2008)
Cell Prolif
, vol.41
, pp. 122-135
-
-
Patel, R.1
Win, H.2
Desai, S.3
Patel, K.4
Matthews, J.A.5
Acevedo-Duncan, M.6
-
34
-
-
33845946450
-
Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical PKC isoforms
-
Pu Y, Peach ML, Garfield SH, Wincovitch S, Marquez VE, Blumberg PM. Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical PKC isoforms. J Biol Chem 281: 33773-33788, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 33773-33788
-
-
Pu, Y.1
Peach, M.L.2
Garfield, S.H.3
Wincovitch, S.4
Marquez, V.E.5
Blumberg, P.M.6
-
35
-
-
0032932198
-
p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signaling complex
-
Romanelli A, Martin KA, Toker A, Blenis J. p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signaling complex. Mol Cell Biol 19: 2921-2928, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2921-2928
-
-
Romanelli, A.1
Martin, K.A.2
Toker, A.3
Blenis, J.4
-
36
-
-
67349090336
-
Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance
-
Sajan MP, Standaert ML, Rivas J, Miura A, Kanoh Y, Soto J, Taniguchi CM, Kahn CR, Farese RV. Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance. Diabetologia 52: 1197-1207, 2009.
-
(2009)
Diabetologia
, vol.52
, pp. 1197-1207
-
-
Sajan, M.P.1
Standaert, M.L.2
Rivas, J.3
Miura, A.4
Kanoh, Y.5
Soto, J.6
Taniguchi, C.M.7
Kahn, C.R.8
Farese, R.V.9
-
37
-
-
74949121815
-
AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK- and PDK1-dependent activation of atypical PKC
-
doi:10.1152/ajpendo.00392
-
Sajan MP, Bandyopadhyay G, Miura A, Standaert M, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn CR, Braun U, Leitges M, Farese RV. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK- and PDK1-dependent activation of atypical PKC. Am J Physiol Endocrinol Metab. doi:10.1152/ajpendo.00392.2009.
-
(2009)
Am J Physiol Endocrinol Metab
-
-
Sajan, M.P.1
Bandyopadhyay, G.2
Miura, A.3
Standaert, M.4
Nimal, S.5
Longnus, S.L.6
Van Obberghen, E.7
Hainault, I.8
Foufelle, F.9
Kahn, C.R.10
Braun, U.11
Leitges, M.12
Farese, R.V.13
-
38
-
-
33745198007
-
Repletion of atypical protein kinase C following RNA interference-mediated depletion restores insulin-stimulated glucose transport
-
Sajan MP, Rivas J, Li P, Standaert ML, Farese RV. Repletion of atypical protein kinase C following RNA interference-mediated depletion restores insulin-stimulated glucose transport. J Biol Chem 281: 17466-17473, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 17466-17473
-
-
Sajan, M.P.1
Rivas, J.2
Li, P.3
Standaert, M.L.4
Farese, R.V.5
-
39
-
-
0032697545
-
PKC-ζ and PDK-1 are required for insulin-induced activation of ERK2 in rat adipocytes
-
Sajan MP, Standaert ML, Bandyopadhyay G, Quon MJ, Burke TR, Farese RV. PKC-ζ and PDK-1 are required for insulin-induced activation of ERK2 in rat adipocytes. J Biol Chem 274: 30495-30500, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 30495-30500
-
-
Sajan, M.P.1
Standaert, M.L.2
Bandyopadhyay, G.3
Quon, M.J.4
Burke, T.R.5
Farese, R.V.6
-
40
-
-
4043049693
-
-
3 in cultured pre-adipocyte-derived adipocytes and myotubes of obese subjects. J Clin Endocrinol Metab 89: 3994-3998, 2004.
-
3 in cultured pre-adipocyte-derived adipocytes and myotubes of obese subjects. J Clin Endocrinol Metab 89: 3994-3998, 2004.
-
-
-
-
41
-
-
5044228079
-
Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice
-
Sajan MP, Standaert ML, Miura A, Kahn CR, Farese RV. Tissue-specific differences in activation of atypical protein kinase C and protein kinase B in muscle, liver, and adipocytes of insulin receptor substrate-1 knockout mice. Mol Endocrinol 18: 2513-2521, 2004.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2513-2521
-
-
Sajan, M.P.1
Standaert, M.L.2
Miura, A.3
Kahn, C.R.4
Farese, R.V.5
-
42
-
-
67650564157
-
Critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFκB in obesity
-
Sajan MP, Standaert ML, Nimal S, Varanasi U, Pastoor T, Mastorides S, Braun U, Leitges M, Farese RV. Critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFκB in obesity. J Lipid Res 50: 1133-1145, 2009.
-
(2009)
J Lipid Res
, vol.50
, pp. 1133-1145
-
-
Sajan, M.P.1
Standaert, M.L.2
Nimal, S.3
Varanasi, U.4
Pastoor, T.5
Mastorides, S.6
Braun, U.7
Leitges, M.8
Farese, R.V.9
-
43
-
-
58149089889
-
80K-H acts as a signaling bridge in intact living cells between PKCzeta and the GLUT4 translocation regulator Munc18c
-
Smithers NP, Hodgkinson CP, Cuttle M, Sale GJ. 80K-H acts as a signaling bridge in intact living cells between PKCzeta and the GLUT4 translocation regulator Munc18c. J Recept Signal Transduct Res 28: 581-589, 2008.
-
(2008)
J Recept Signal Transduct Res
, vol.28
, pp. 581-589
-
-
Smithers, N.P.1
Hodgkinson, C.P.2
Cuttle, M.3
Sale, G.J.4
-
44
-
-
0034721863
-
Unique structure and functional properties of the ATP-binding domain of atypical protein kinase C-iota
-
Spitaler M, Villunger A, Grunicke H, Uberall F. Unique structure and functional properties of the ATP-binding domain of atypical protein kinase C-iota. J Biol Chem 275: 33289-33296, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 33289-33296
-
-
Spitaler, M.1
Villunger, A.2
Grunicke, H.3
Uberall, F.4
-
45
-
-
32944470373
-
A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells
-
Stallings-Mann M, Jamieson L, Regala RP, Weems C, Murray NR, Fields AP. A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells. Cancer Res 66: 1767-1774, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 1767-1774
-
-
Stallings-Mann, M.1
Jamieson, L.2
Regala, R.P.3
Weems, C.4
Murray, N.R.5
Fields, A.P.6
-
46
-
-
0033305732
-
Effects of knockout of the PKC-β gene on glucose transport and glucose homeostasis
-
Standaert ML, Bandyopadhyay G, Galloway L, Soto J, Ono Y, Kikkawa U, Farese RV, Leitges M. Effects of knockout of the PKC-β gene on glucose transport and glucose homeostasis. Endocrinology 140: 4470-4477, 1999.
-
(1999)
Endocrinology
, vol.140
, pp. 4470-4477
-
-
Standaert, M.L.1
Bandyopadhyay, G.2
Galloway, L.3
Soto, J.4
Ono, Y.5
Kikkawa, U.6
Farese, R.V.7
Leitges, M.8
-
47
-
-
0035830320
-
3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites
-
3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites. Biochemistry 40: 249-255, 2001.
-
(2001)
Biochemistry
, vol.40
, pp. 249-255
-
-
Standaert, M.L.1
Bandyopadhyay, G.2
Kanoh, Y.3
Sajan, M.P.4
Farese, R.V.5
-
48
-
-
0033520373
-
Insulin activates PKC-ζ and PKC-λ by an autophosphorylation- dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes
-
Standaert ML, Bandyopadhyay G, Perez L, Price D, Galloway L, Poklepovic A, Sajan MP, Cenni V, Sirri A, Moscat J, Toker A, Farese RV. Insulin activates PKC-ζ and PKC-λ by an autophosphorylation- dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes. J Biol Chem 274: 25308-25316, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 25308-25316
-
-
Standaert, M.L.1
Bandyopadhyay, G.2
Perez, L.3
Price, D.4
Galloway, L.5
Poklepovic, A.6
Sajan, M.P.7
Cenni, V.8
Sirri, A.9
Moscat, J.10
Toker, A.11
Farese, R.V.12
-
49
-
-
0030810216
-
Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport
-
Standaert ML, Galloway L, Karnam P, Bandyopadhyay G, Moscat J, Farese RV. Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. J Biol Chem 272: 30075-30082, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 30075-30082
-
-
Standaert, M.L.1
Galloway, L.2
Karnam, P.3
Bandyopadhyay, G.4
Moscat, J.5
Farese, R.V.6
-
50
-
-
0036787463
-
Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota
-
Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, Farese RV. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Diabetes 51: 2936-2943, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 2936-2943
-
-
Standaert, M.L.1
Ortmeyer, H.K.2
Sajan, M.P.3
Kanoh, Y.4
Bandyopadhyay, G.5
Hansen, B.C.6
Farese, R.V.7
-
51
-
-
2942530449
-
Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states
-
Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states. J Biol Chem 279: 24929-24934, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 24929-24934
-
-
Standaert, M.L.1
Sajan, M.P.2
Miura, A.3
Kanoh, Y.4
Chen, H.C.5
Farese Jr, R.V.6
Farese, R.V.7
-
52
-
-
0042493623
-
Atypical protein kinase C isozyme zeta mediates carbachol-stimulated insulin secretion in RINm5F cells
-
Tang SH, Sharp GW. Atypical protein kinase C isozyme zeta mediates carbachol-stimulated insulin secretion in RINm5F cells. Diabetes 47: 905-912, 1998.
-
(1998)
Diabetes
, vol.47
, pp. 905-912
-
-
Tang, S.H.1
Sharp, G.W.2
-
53
-
-
33646148946
-
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta
-
Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta. Cell Metab 3: 343-353, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 343-353
-
-
Taniguchi, C.M.1
Kondo, T.2
Sajan, M.3
Luo, J.4
Bronson, R.5
Asano, T.6
Farese, R.7
Cantley, L.C.8
Kahn, C.R.9
-
54
-
-
71949113900
-
Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses
-
Thaler JP, Choi SJ, Sajan MP, Ogimoto K, Nguyen HT, Matsen M, Benoit SC, Wisse BE, Farese RV, Schwartz MW. Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses. Endocrinology 150: 5362-5372, 2009.
-
(2009)
Endocrinology
, vol.150
, pp. 5362-5372
-
-
Thaler, J.P.1
Choi, S.J.2
Sajan, M.P.3
Ogimoto, K.4
Nguyen, H.T.5
Matsen, M.6
Benoit, S.C.7
Wisse, B.E.8
Farese, R.V.9
Schwartz, M.W.10
-
55
-
-
18544407572
-
Restored insulin sensitivity in IRS-1-deficient mice treated by adenovirus-meduated gene therapy
-
Ueki K, Yamauchi T, Takemoto H, Tobe K, Yamamoto-Honda R, Kaburagi Y, Akanuma Y, Yazaki Y, Aizawa S, Nagai R, Kadowaki T. Restored insulin sensitivity in IRS-1-deficient mice treated by adenovirus-meduated gene therapy. J Clin Invest 105: 1437-1445, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 1437-1445
-
-
Ueki, K.1
Yamauchi, T.2
Takemoto, H.3
Tobe, K.4
Yamamoto-Honda, R.5
Kaburagi, Y.6
Akanuma, Y.7
Yazaki, Y.8
Aizawa, S.9
Nagai, R.10
Kadowaki, T.11
-
56
-
-
0042822138
-
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes
-
Valverde AM, Burks DJ, Fabregat I, Fisher TL, Carretero J, White MF, Benito M. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes. Diabetes 52: 2239-2248, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 2239-2248
-
-
Valverde, A.M.1
Burks, D.J.2
Fabregat, I.3
Fisher, T.L.4
Carretero, J.5
White, M.F.6
Benito, M.7
-
57
-
-
0036227755
-
Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3′ kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance
-
Vollenweider P, Ménard B, Nicod P. Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3′ kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance. Diabetes 51: 1052-1059, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 1052-1059
-
-
Vollenweider, P.1
Ménard, B.2
Nicod, P.3
-
58
-
-
0035193041
-
Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway
-
Wooten MW, Vandenplas ML, Seibenhener ML, Geetha T, Diaz-Meco MT. Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway. Mol Cell Biol 21: 8414-8427, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8414-8427
-
-
Wooten, M.W.1
Vandenplas, M.L.2
Seibenhener, M.L.3
Geetha, T.4
Diaz-Meco, M.T.5
-
59
-
-
0029897280
-
Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice
-
Yamauchi T, Tobe K, Tamemoto H, Ueki K, Kaburagi Y, Yamamoto-Honda R, Takahashi Y, Yoshizawa F, Aizawa S, Akanuma Y, Sonenberg N, Yazaki Y, Kadowaki T. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice. Mol Cell Biol 16: 3074-3084, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3074-3084
-
-
Yamauchi, T.1
Tobe, K.2
Tamemoto, H.3
Ueki, K.4
Kaburagi, Y.5
Yamamoto-Honda, R.6
Takahashi, Y.7
Yoshizawa, F.8
Aizawa, S.9
Akanuma, Y.10
Sonenberg, N.11
Yazaki, Y.12
Kadowaki, T.13
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