Atypical protein kinase C isozyme ζ mediates carbachol-stimulated insulin secretion in RINm5F cells

Diabetes

Volumn 47, Issue 6, 1998, Pages 905-912

  Tang, Shao Hua ^a   Sharp, Geoffrey W G ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARBACHOL; PROTEIN KINASE C;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SUBSTRATE; IMMUNOBLOTTING; INSULIN RELEASE; PRIORITY JOURNAL; PROTEIN TRANSPORT;

ANIMALS; CARBACHOL; CELL MEMBRANE; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITORS; INSULIN; INSULINOMA; ISOENZYMES; PANCREATIC NEOPLASMS; PROTEIN KINASE C; STAUROSPORINE; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0042493623     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.6.905     Document Type: Article

References (55)

1. Mathias PC, Best L, Malaisse WJ: Stimulation by glucose and carbamylcholine of phospholipase C in pancreatic islets. Cell Biochem Funct 3:173-177, 1985
2. Petit P, Manteghetti M, Loubatieres-Mariani MM: Differential effects of purinergic and cholinergic activation on the hydrolysis of membrane polyphosphoinositides in rat pancreatic islets. Biochem Pharmacol 37:1213-1217, 1988
3. Blachier F, Malaisse WJ: Possible role of a GTP-binding protein in the activation of phospholipase C by carbamylcholine in tumoral insulin-producing cells. Res Comm Chem Pathol Pharmacol 58:237-255, 1987
4. Wollheim CB, Biden TJ: Second messenger function of inositol 1,4,5-trisphophate. J Biol Chem 261:8314-8319, 1986
5. Berridge MJ, Irvine RF: Inositol trisphosphate: a novel second messenger in cellular signal transduction. Nature 312:315-321, 1984
6. Nishizuka Y: The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665, 1988
7. Wolf BA, Eason RA, Hughes JH, McDaniel ML, Urek J: Secretagogue-induced diacylglycerol accumulation in isolated pancreatic islets: mass spectrometric characterization of the fatty acyl content indicates multiple mechanisms of generation. Biochemistry 28:4291-4301, 1989
8. Easom RA, Land M, Colca JR, Hughes JH, Turk J, McDaniel M: Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets. J Biol Chem 265:14938-14946, 1990
9. 2+ and a phorbol ester on insulin secretion from islets of Langerhans permeabilised by high-voltage discharge. FEBS Lett 191:102-106, 1985
10. Jones PM, Persaud SJ, Howell SL: Protein kinase C and the regulation of insulin secretion from pancreatic B cells. J Mol Endocrinol 6:121-127, 1991
11. 2+ and protein kinase C in acetylcholine-induced insulin release in the clonal β-cell line, HIT-T15. Biochem J 267:227-232, 1990
12. Tang SH, Yaney GC, Sharp GWG: Unusual carbachol responses in RINm5F cells: evidence for a "distal" site of action in stimulus-secretion coupling. Mol Pharmacol 47:863-870, 1995
13. Bonner TI, Buckley NJ, Young AC, Brann MR: Identification of a family of muscarinic acetylcholine receptor genes. Science 237:527-532, 1987
14. Bonner TI, Young AC, Brann MR, Buckley NJ: Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron 1:403-410, 1988
15. Tang SH, Sharp GWG: Identification of muscarinic receptor subtypes in RINm5F cells by means of polymerase chain reaction, subcloning and DNA sequencing. Diabetes 46:1419-1423, 1997
16. Hosey MM: Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors. FASEB J 6:845-852, 1992
17. Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614, 1992
18. Hug H, Sarre TF: Protein kinase C isoenzymes: divergence in signal transduction? Biochem J 291:329-343, 1993
19. Parker PJ, Kour G, Marais RM, Mitchell F, Pears C, Schaap D, Stabel S, Webster C: Protein kinase C: a family affair. Mol Cell Endocrinol 65:1-11, 1989
20. Ohno S, Akita Y, Hata A, Osada S, Kubo K, Konno Y, Akimoto K, Mizuno K, Saido T, Kuroki T, Suzuki K: Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and novel nPKC. Adv Enzyme Regul 31:287-303, 1991
21. Kiley S, Schaap D, Parker PJ, Hsieh L-L, Jaken S: Protein kinase C heterogeneity in GH4C1 rat pituitary cells. J Biol Chem 265:15704-15712, 1990
22. Olivier AR, Parker PJ: Expression and characterization of PKC-δ. Eur J Biochem 200:805-810, 1991
23. Nakanishi H, Exton JH: Purification and characterization of the zeta isoform of protein kinase C from bovine kidney. J Biol Chem 267:16347-16354, 1992
24. Nakanishi H, Brewer KA, Exton JH: Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 208:13-16, 1993
25. Selbie LA, Schmitz-Peiffer C, Sheng Y, Biden TJ: Molecular cloning and characterization of PKC iota: an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem 268:24296-24302, 1993
26. Johannes FJ, Preslte J, Eis S, Oberhagenann P, Pfizenmaier K: PKCμ is a novel, atypical member of the protein kinase C family. J Biol Chem 269:6140-6148, 1994
27. Olivier AR, Parker PJ: Identification of multiple PKC isoforms in Swiss 3T3 cells: differential downregulation by phorbol ester. J Cell Physiol 152:240-244, 1992
28. Kochs G, Hummel R, Meyer D, Hug H, Marme D, Sarre TF: Activation and substrate specificity of the human protein kinase C alpha and zeta isozymes. Eur J Biochem 216:597-606, 1993
29. Rennecke J, Johannes FJ, Richter KH, Kittstein W, Marks F, Gschwendt M: Immunological demonstration of protein kinase C mu in murine tissues and various cell lines: differential recognition of phosphorylated forms und lack of downregulation upon 12-O-tetradecanoylphorphol-13-acetate treatment of cells. Eur J Biochem 242:428-432, 1996
30. Akimoto K, Mizuno K, Osada S, Hirai S, Tanuma S, Suzuki K, Ohno S: A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells. J Biol Chem 269:12677-12683, 1994
31. Knutson KL, Hoenig M: Identification and subcellular characterization of protein kinase-C isoforms in insulinoma beta-cells and whole islets. Endocrinology 135:881-886, 1994
32. Tian YM, Urquidi V, Ashcroft SJ: Protein kinase C in beta-cells: expression of multiple isoforms and involvement in cholinergic stimulation of insulin secretion. Mol Cell Endocrinol 119:185-193, 1996
33. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685, 1970
34. Nishizuka Y: The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665, 1988
35. Young S, Parker PJ, Ullrich A, Stabel S: Downregulation of protein kinase C is due to on increased rate of degradation. Biochem J 244:775-779, 1987
36. Eichholtz T, de Bont DB, de Widt J, Liskamp RM, Ploegh HL: A myristoylated pseudosubstrate peptide: a novel protein kinase C inhibitor. J Biol Chem 268:1982-1986, 1993
37. i oscillations in single intact rat hepatocytes. Cell Calcium 18:232-244, 1995
38. Harris TE, Persaud SJ, Saermark T, Jones PM: A myristoylated pseudosubstrate peptide inhibitor of protein kinase C: effects on glucose- and carbachol-induced insulin secretion. Mol Cell Endocrinol 121:133-141, 1996
39. Dominguez I, Diaz-meco MT, Municio MM, Berra E, de Herreros AG, Cornet ME, Sanz L, Moscat J: Evidence for a role of protein kinase C ζ subspecies in maturation of Xenopus laevis oocytes. Mol Cell Biol 12:3776-3783, 1992
40. De BP, Gupta S, Gupta S, and Banerjee AK: Cellular protein kinase C isoform ζ regulates human parainfluenza virus type 3 replication. Proc Natl Acad Sci 92:5204-5208, 1995
41. Gschwendt M, Furstenberger G, Leibersperger H, Kittstein W, Lindner D, Rudolph C, Barth H, Kleinschroth J, Marme D, Schachtele C, Marks F: Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo. Carcinogenesis 16:107-111, 1995
42. Zang R, Muller HJ, Kielbassa K, Marks F, Gschwendt M: Partial purification of a type eta protein kinase C from murine brain: separation from other protein kinase C isoenzymes and characterization. Biochem J 304:641-647, 1994
43. Seynaeve CM, Kazanietz MG, Blumberg PM, Sausville EA, Worland PJ: Differential inhibition of protein kinase C isozymes by UCN-01: a staurosporine analogue. Mol Pharmacol 45:1207-1214, 1994
44. Wilkinson SE, Parker PJ, Nixon JS: Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J 294:335-337, 1993
45. Johnson MS, MacEwan DJ, Simpson J, Mitchell R: Characterization of protein kinase C isoforms and enzymic activity from the alpha T3-1 gonadotroph-derived cell line. FEBS Lett 333:67-72, 1993
46. Cabedo H, Minana MD, Grau E, Felipo V, Grisolla S: Protein kinase C isoforms and cell proliferation in neuroblastoma cells. Brain Res Mol Brain Res 37:125-133, 1996
47. Johannes FJ, Prestle J, Dieterich S, Oberhagemann P, Lind G, Pfizenmaier K: Characterization of activators and inhibitors of protein kinase C mu. Eur J Biochem 227:303-307, 1995
48. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charom D, Kirilovsky J: The bisindolylmaleimide GF 109203X is a potent and selective inhibitory protein kinase C. J Biol Chem 266:15771-15781, 1991
49. Van Blitterswijk WJ, Van der Bend RL, Kramer LJM, Verhoeven AL, Hilkman H, de Widt J: A metabolite of an antineoplastic ether phospholipid may inhibit transmembrane signalling via protein kinase C. Lipids 22:842-846, 1987
50. Ono Y, Fujii T, Ogita K, Kikkawa U, Igarashi K, Nishizuka Y: Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties. Proc Natl Acad Sci, USA 86:3099-30103, 1989
51. McGlynn E, Liebetanz J, Reutener S, Wood J, Lydon NB, Hofstetter H, Vanek M, Meyer T, Fabbro D: Expression and partial characterization of rat protein kinase C-delta and protein kinase C-zeta in insect cells using recombinant baculovirus. J Cell Biochem 49:239-250, 1992
52. Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF, Mischak H: The cDNA sequence: expression pattern and protein characteristics of mouse protein kinase C-zeta. Gene 122:305-311, 1992
53. Li GD, Regazzi R, Ullrich S, Pralong WF, Wollheim CB: Potentiation of stimulus-induced insulin secretion in protein kinase C-deficient RINm5F cells. Biochem J 272:637-645, 1990
54. Persaud SJ, Jones PM, Sugden D, Howell S: The role of protein kinase C in cholinergic stimulation of insulin secretion from rat islets of Langerhans. Biochem J 264:753-758, 1989
55. Gao ZY, Gilon P, Henquin JC: The role of protein kinase-C in signal transduction through vasopressin and acetylcholine receptors in pancreatic B cells from normal mouse. Endocrinology 135:191-199, 1994