Activation of protein kinase C-ζ by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: Amelioration by rosiglitazone and exercise

Diabetes

Volumn 52, Issue 8, 2003, Pages 1926-1934

  Beeson, Mary ^a   Sajan, Mini P ^a   Dizon, Michelle ^a,b   Grebenev, Dmitry ^a,b   Gomez Daspet, Joaquin ^a,b   Miura, Atsushi ^a,b   Kanoh, Yoshinori ^a,b   Powe, Jennifer ^a,b   Bandyopadhyay, Gautam ^a,b   Standaert, Mary L ^a,b   Farese, Robert V ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; METFORMIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C ZETA; ROSIGLITAZONE; SULFONYLUREA DERIVATIVE;

ADULT; ARTICLE; BICYCLE ERGOMETER; CLAMP; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXERCISE; FEMALE; GLUCOSE TRANSPORT; HORMONE ACTION; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; MALE; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; EXERCISE; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TRANSPORTER TYPE 4; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; ISOENZYMES; MALE; MIDDLE AGED; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; THIAZOLES; THIAZOLIDINEDIONES;

EID: 0042093782     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.8.1926     Document Type: Article

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