Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

Cell Metabolism

Volumn 3, Issue 5, 2006, Pages 343-353

  Taniguchi, Cullen M ^a   Kondo, Tatsuya ^b   Sajan, Mini ^c   Luo, Ji ^a,d   Bronson, Roderick ^a   Asano, Tomoichiro ^e   Farese, Robert ^c   Cantley, Lewis C ^a,d   Kahn, C Ronald ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

SIGNALING

Indexed keywords

GLUCOSE; INSULIN; LIPID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C LAMBDA; PROTEIN KINASE C ZETA; PROTEIN SUBUNIT; REGULATOR PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GLUCONEOGENESIS; HYPERINSULINEMIA; HYPOLIPEMIA; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; KNOCKOUT MOUSE; LIPID METABOLISM; LIVER CELL; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOSE TISSUE; ANIMALS; GLUCONEOGENESIS; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; ISOENZYMES; LIPID METABOLISM; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMALIA;

EID: 33646148946     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2006.04.005     Document Type: Article

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