PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells

Journal of Clinical Investigation

Volumn 115, Issue 1, 2005, Pages 138-145

  Hashimoto, Naoko ^a   Kido, Yoshiaki ^a,b   Uchida, Tohru ^a   Matsuda, Tomokazu ^a   Suzuki, Kazuhisa ^b   Inoue, Hiroshi ^a   Matsumoto, Michihiro ^a   Ogawa, Wataru ^a   Maeda, Sakan ^b   Fujihara, Hiroaki ^c   Ueta, Yoichi ^c   Uchiyama, Yasuo ^d   Akimoto, Kazunori ^e   Ohno, Shigeo ^e   Noda, Tetsuo ^f   Kasuga, Masato ^a  

^a Div of Diabet/Digest/Kidney Dis ^*  (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e YOKOHAMA CITY UNIVERSITY   (Japan)

^f CANCER INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GLUCOSE; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 3; HEPATOCYTE NUCLEAR FACTOR 3BETA; HEXOKINASE; HEXOKINASE 2; HEXOKINASE ISOENZYME; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; ISOENZYME; MESSENGER RNA; PROTEIN KINASE C LAMBDA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; FOXA2 PROTEIN, MOUSE; NUCLEAR PROTEIN; PROTEIN KINASE C; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; EXPERIMENTAL MODEL; GENE EXPRESSION REGULATION; HYPOINSULINEMIA; IMMUNOHISTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; KNOCKOUT MOUSE; MOUSE; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE LEVEL; ANIMAL; CYTOLOGY; DRUG EFFECT; ELECTRON MICROSCOPY; FAT INTAKE; GENE DELETION; GENETICS; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; SECRETION;

ANIMALS; DIETARY FATS; DNA-BINDING PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 3-BETA; INSULIN; ISLETS OF LANGERHANS; ISOENZYMES; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; NUCLEAR PROTEINS; PROTEIN KINASE C; TRANSCRIPTION FACTORS;

EID: 85047693987     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI22232     Document Type: Article

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