Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Diabetologia

Volumn 52, Issue 6, 2009, Pages 1197-1207

  Sajan, M P ^a   Standaert, M L ^a   Rivas, J ^a   Miura, A ^a   Kanoh, Y ^a   Soto, J ^a   Taniguchi, C M ^b   Kahn, C R ^b   Farese, R V ^a,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROSKAMP INSTITUTE   (United States)

Author keywords

Atypical protein kinase C; Diabetes; Insulin; IRS 1; IRS 2; Liver; Muscle; Protein kinase B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; SHORT HAIRPIN RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ADENOVIRUS; ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; ENZYME INHIBITION; GOTO KAKIZAKI RAT; HYPERLIPIDEMIA; INFLAMMATION; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CHOLESTEROL; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HYPERLIPIDEMIAS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIVER; MALE; MUSCLES; NF-KAPPA B; PROTEIN KINASE C; RATS; RATS, WISTAR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES;

EID: 67349090336     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1336-5     Document Type: Article

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