메뉴 건너뛰기




Volumn 51, Issue 10, 2002, Pages 2936-2943

Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-ζ/λ/ι

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C IOTA; PROTEIN KINASE C LAMBDA; PROTEIN KINASE C ZETA; UNCLASSIFIED DRUG;

EID: 0036787463     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.10.2936     Document Type: Article
Times cited : (62)

References (32)
  • 1
    • 0033536157 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance in humans
    • Shulman GI: Cellular mechanisms of insulin resistance in humans. Am J Cardiol 84:3J-10J, 1999
    • (1999) Am J Cardiol , vol.84
    • Shulman, G.I.1
  • 2
    • 0024026298 scopus 로고
    • The triumvirate: β-cell, muscle, liver: A collusion responsible for NIDDM
    • DeFronzo RA: The triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM. Diabetes 37:667-687, 1988
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 3
    • 0026624835 scopus 로고
    • Facilitative glucose transporters: Regulatory mechanisms and dysregulation in diabetes
    • Kahn BB: Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. J Clin Invest 89:1367-1374, 1992
    • (1992) J Clin Invest , vol.89 , pp. 1367-1374
    • Kahn, B.B.1
  • 5
    • 0029908016 scopus 로고    scopus 로고
    • Expression of a constitutively active Akt Ser/Thr kinase in 3T3/L 1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
    • Kohn AD, Summers SA, Birnbaum MJ, Roth RA: Expression of a constitutively active Akt Ser/Thr kinase in 3T3/L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271:31372-31378, 1996
    • (1996) J Biol Chem , vol.271 , pp. 31372-31378
    • Kohn, A.D.1    Summers, S.A.2    Birnbaum, M.J.3    Roth, R.A.4
  • 7
    • 0033049422 scopus 로고    scopus 로고
    • Protein kinase B/Akt participates in Glut4 translocation by insulin in L6 myoblasts
    • Wang Q, Somwar R, Bilan PJ, Liu Z, Jin J, Woodgett JR, Klip A: Protein kinase B/Akt participates in Glut4 translocation by insulin in L6 myoblasts. Mol Cell Biol 19:4008-4018, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 4008-4018
    • Wang, Q.1    Somwar, R.2    Bilan, P.J.3    Liu, Z.4    Jin, J.5    Woodgett, J.R.6    Klip, A.7
  • 8
    • 0031038052 scopus 로고    scopus 로고
    • Activation of protein kinase C (α, β, and ζ) by insulin in 3T3/L1 cells: Transfection studies suggest a role for PKC-ζ in glucose transport
    • Bandyopadhyay G, Standaert MI, Zhao L, Yu B, Avignon A, Galloway L, Karnam P, Moscat J, Farese RV: Activation of protein kinase C (α, β, and ζ) by insulin in 3T3/L1 cells: transfection studies suggest a role for PKC-ζ in glucose transport. J Biol Chem 272:2551-2558, 1997
    • (1997) J Biol Chem , vol.272 , pp. 2551-2558
    • Bandyopadhyay, G.1    Standaert, M.I.2    Zhao, L.3    Yu, B.4    Avignon, A.5    Galloway, L.6    Karnam, P.7    Moscat, J.8    Farese, R.V.9
  • 9
    • 0030812546 scopus 로고    scopus 로고
    • Evidence for involvement of protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L 6 myotubes
    • Bandyopadhyay G, Standaert ML, Galloway L, Moscat J, Farese RV: Evidence for involvement of protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 138:4721-4731, 1997
    • (1997) Endocrinology , vol.138 , pp. 4721-4731
    • Bandyopadhyay, G.1    Standaert, M.L.2    Galloway, L.3    Moscat, J.4    Farese, R.V.5
  • 10
    • 0030810216 scopus 로고    scopus 로고
    • Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes: Potential role in glucose transport
    • Standaert ML, Galloway L, Karnam P, Bandyopadhyay G, Moscat J, Farese RV: Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes: potential role in glucose transport. J Biol Chem 272:30075-30082, 1997
    • (1997) J Biol Chem , vol.272 , pp. 30075-30082
    • Standaert, M.L.1    Galloway, L.2    Karnam, P.3    Bandyopadhyay, G.4    Moscat, J.5    Farese, R.V.6
  • 11
    • 0033082749 scopus 로고    scopus 로고
    • Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ε) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged Glut4 glucose transporters in rat adipocytes: Specific interchangeable effects of protein kinases C-ζ and C-λ
    • Bandyopadhyay G, Standaert ML, Kikkawa U, Ono Y, Moscat J, Farese RV: Effects of transiently expressed atypical (ζ, λ), conventional (α, β) and novel (δ, ε) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged Glut4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-ζ and C-λ. Biochem J 337:461-470, 1999
    • (1999) Biochem J , vol.337 , pp. 461-470
    • Bandyopadhyay, G.1    Standaert, M.L.2    Kikkawa, U.3    Ono, Y.4    Moscat, J.5    Farese, R.V.6
  • 13
    • 0031057526 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
    • Bjornholm M, Kawano Y, Lehtihet M, Zierath JR: Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes 46:524-527, 1997
    • (1997) Diabetes , vol.46 , pp. 524-527
    • Bjornholm, M.1    Kawano, Y.2    Lehtihet, M.3    Zierath, J.R.4
  • 14
    • 0031852665 scopus 로고    scopus 로고
    • Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
    • Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H: Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47:1281-1286, 1998
    • (1998) Diabetes , vol.47 , pp. 1281-1286
    • Krook, A.1    Roth, R.A.2    Jiang, X.J.3    Zierath, J.R.4    Wallberg-Henriksson, H.5
  • 15
    • 0032698470 scopus 로고    scopus 로고
    • Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
    • Kim Y-B, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB: Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J Clin Invest 104:733-741, 1999
    • (1999) J Clin Invest , vol.104 , pp. 733-741
    • Kim, Y.-B.1    Nikoulina, S.E.2    Ciaraldi, T.P.3    Henry, R.R.4    Kahn, B.B.5
  • 16
    • 0002483918 scopus 로고    scopus 로고
    • Insulin-stimulated PKC-λ/ζ activity is impaired in muscle of insulin-resistant subjects
    • Kim Y-B, Kotani K, Ciaraldi TP, Farese RV, Henry RR, Kahn BB: Insulin-stimulated PKC-λ/ζ activity is impaired in muscle of insulin-resistant subjects (Abstract). Diabetes 50 (Suppl. 2):A62, 2001
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Kim, Y.-B.1    Kotani, K.2    Ciaraldi, T.P.3    Farese, R.V.4    Henry, R.R.5    Kahn, B.B.6
  • 17
    • 0035053628 scopus 로고    scopus 로고
    • Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-ζ/λ by insulin in vastus lateralis muscles and adipocytes of diabetic rats
    • Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV: Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-ζ/λ by insulin in vastus lateralis muscles and adipocytes of diabetic rats. Endocrinology 142:1595-1605, 2001
    • (2001) Endocrinology , vol.142 , pp. 1595-1605
    • Kanoh, Y.1    Bandyopadhyay, G.2    Sajan, M.P.3    Standaert, M.L.4    Farese, R.V.5
  • 18
    • 0035432971 scopus 로고    scopus 로고
    • Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atuypical protein kinase (ζ/λ) activities
    • Tremblay F, Lavigne C, Jaques H, Marette A: Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atuypical protein kinase (ζ/λ) activities. Diabetes 50:1901-1910, 2001
    • (2001) Diabetes , vol.50 , pp. 1901-1910
    • Tremblay, F.1    Lavigne, C.2    Jaques, H.3    Marette, A.4
  • 19
    • 0022868041 scopus 로고
    • Heterogeneity of insulin responses: Phases leading to type 2 (non-insulin-dependent) diabetes mellitus in the rhesus monkey
    • Hansen BC, Bodkin NL: Heterogeneity of insulin responses: phases leading to type 2 (non-insulin-dependent) diabetes mellitus in the rhesus monkey. Diabetologia 29:713-719, 1986
    • (1986) Diabetologia , vol.29 , pp. 713-719
    • Hansen, B.C.1    Bodkin, N.L.2
  • 20
    • 0024523898 scopus 로고
    • Hepatic glucose production and insulin sensitivity preceding diabetes in monkeys
    • Bodkin NL, Metzger BL, Hansen BC: Hepatic glucose production and insulin sensitivity preceding diabetes in monkeys. Am J Physiol 256: E676-E681, 1989
    • (1989) Am J Physiol , vol.256
    • Bodkin, N.L.1    Metzger, B.L.2    Hansen, B.C.3
  • 21
    • 0025182175 scopus 로고
    • β-cell hyperresponsiveness: Earliest event in development of diabetes in monkeys
    • Hansen BC, Bodkin NL: β-Cell hyperresponsiveness: earliest event in development of diabetes in monkeys. Am J Physiol 259:R612-R617, 1990
    • (1990) Am J Physiol , vol.259
    • Hansen, B.C.1    Bodkin, N.L.2
  • 22
    • 0029366031 scopus 로고
    • Prevention of obesity in nuddle-aged monkeys: Food intake during body weight clamp
    • Hansen BC, Ortmeyer HK, Bodkin NL: Prevention of obesity in nuddle-aged monkeys: food intake during body weight clamp. Obes Res 3 (Suppl. 2):199S-204S, 1995
    • (1995) Obes Res , vol.3 , Issue.SUPPL. 2
    • Hansen, B.C.1    Ortmeyer, H.K.2    Bodkin, N.L.3
  • 23
    • 0027437865 scopus 로고
    • Primary prevention of diabetes mellitus by prevention of obesity in monkeys
    • Hansen BC, Bodkin NL: Primary prevention of diabetes mellitus by prevention of obesity in monkeys. Diabetes 42:1809-1814, 1993
    • (1993) Diabetes , vol.42 , pp. 1809-1814
    • Hansen, B.C.1    Bodkin, N.L.2
  • 24
    • 0029143129 scopus 로고
    • Long-term dietary restriction in older-aged rhesus monkeys: Effects on insulin resistance
    • Bodkin NL, Ortmeyer HK, Hansen BC: Long-term dietary restriction in older-aged rhesus monkeys: effects on insulin resistance. J Gerontol A Biol Sci Med Sci 50A:B142-B147, 1995
    • (1995) J Gerontol A Biol Sci Med Sci , vol.50 A
    • Bodkin, N.L.1    Ortmeyer, H.K.2    Hansen, B.C.3
  • 25
    • 0024523898 scopus 로고
    • Hepatic glucose production and insulin sensitivity preceding diabetes in monkeys
    • Bodkin NL, Metzger BL, Hansen BC: Hepatic glucose production and insulin sensitivity preceding diabetes in monkeys. Am J Physiol 256:E676E681, 1989
    • (1989) Am J Physiol , vol.256
    • Bodkin, N.L.1    Metzger, B.L.2    Hansen, B.C.3
  • 26
    • 0027488879 scopus 로고
    • Insulin-mediated glycogen synthase activity in muscle of spontaneously insulin-resistant and diabetic rhesus monkeys
    • Ortmeyer HK, Bodkin NL, Hansen BC: Insulin-mediated glycogen synthase activity in muscle of spontaneously insulin-resistant and diabetic rhesus monkeys. Am J Physiol 265:R552-558., 1993
    • (1993) Am J Physiol , vol.265
    • Ortmeyer, H.K.1    Bodkin, N.L.2    Hansen, B.C.3
  • 27
    • 0033695810 scopus 로고    scopus 로고
    • Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes
    • Bandyopadhyay G, Kanoh Y, Sajan MP, Standaert ML, Farese RV: Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-λ on insulin-stimulated glucose transport in L6 myotubes. Endocrinology 141:4120-4127, 2000
    • (2000) Endocrinology , vol.141 , pp. 4120-4127
    • Bandyopadhyay, G.1    Kanoh, Y.2    Sajan, M.P.3    Standaert, M.L.4    Farese, R.V.5
  • 30
    • 0035090324 scopus 로고    scopus 로고
    • In vivo insulin regulation of skeletal muscle glycogen synthase in calorie-restricted and in ad libitum-fed rhesus monkeys
    • Ortmeyer HK: In vivo insulin regulation of skeletal muscle glycogen synthase in calorie-restricted and in ad libitum-fed rhesus monkeys. J Nutr 131:907S-912S, 2001
    • (2001) J Nutr , vol.131
    • Ortmeyer, H.K.1
  • 31
    • 0001410299 scopus 로고
    • Chronic caloric restriction alters glycogen metabolism in rhesus monkeys
    • Ortmeyer HK, Bodkin NL, Hansen BC: Chronic caloric restriction alters glycogen metabolism in rhesus monkeys. Obes Res 2:549-555, 1994
    • (1994) Obes Res , vol.2 , pp. 549-555
    • Ortmeyer, H.K.1    Bodkin, N.L.2    Hansen, B.C.3
  • 32
    • 0035830320 scopus 로고    scopus 로고
    • 3 activate PKC-ζ: By mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites
    • 3 activate PKC-ζ: by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites. Biochemistry 40:249-255, 2001
    • (2001) Biochemistry , vol.40 , pp. 249-255
    • Standaert, M.L.1    Bandyopadhyay, G.2    Kanoh, Y.3    Sajan, M.P.4    Farese, R.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.