Cellular disposition of sulphamethoxazole and its metabolites: Implications for hypersensitivity

British Journal of Pharmacology

Volumn 126, Issue 6, 1999, Pages 1393-1407

  Naisbitt, Dean J ^a   Hough, Sally J ^a   Gill, Helen J ^a   Pirmohamed, Munir ^a   Kitteringham, Neil R ^a   Park, B Kevin ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Cellular disposition; Haptenation; Hypersensitivity; Reduction; Sulphamethoxazole

Indexed keywords

CYSTEINE; GLUTATHIONE; SULFAMETHOXAZOLE;

ADULT; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG BINDING; DRUG CONJUGATION; DRUG DISPOSITION; DRUG HYPERSENSITIVITY; DRUG METABOLISM; ERYTHROCYTE; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LEUKOCYTE; LYMPHOCYTE; MALE; MEMBRANE STRUCTURE; NEUTROPHIL; NORMAL HUMAN; OXIDATION; PLASMA; PRIORITY JOURNAL;

EID: 0033001485     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702453     Document Type: Article

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