Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole- specific human αβ+ T cell clones

Journal of Immunology

Volumn 162, Issue 1, 1999, Pages 595-602

  Von Greyerz, Salome ^a   Zanni, Martin P ^a   Frutig, Karin ^a   Schnyder, Benno ^a   Burkhart, Christoph ^a   Pichler, Werner J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LIDOCAINE; SULFAMETHOXAZOLE; SULFONAMIDE; T LYMPHOCYTE RECEPTOR;

ARTICLE; DRUG HYPERSENSITIVITY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CLONE; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; T LYMPHOCYTE;

CLONE CELLS; CROSS REACTIONS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG HYPERSENSITIVITY; EPITOPES, T-LYMPHOCYTE; HUMANS; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SULFAMETHOXAZOLE; SULFONAMIDES; T-LYMPHOCYTE SUBSETS;

EID: 0032960782     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Pichler, W. J., B. Schnyder, M. P. Zanni, Y. Hari, and S. von Greyerz. 1998. Role of T cells in drug allergies. Allergy 53:225.
2. Brander, C., D. Mauri-Hellweg, F. Bettens, H. Rolli, M. Goldman, and W. J. Pichler. 1995. Heterogeneous T cell responses to β-lactam-modified self-structures are observed in penicillin-allergic individuals. J. Immunol. 155:2670.
3. + T cells in individuals allergic to sulfonamides, phenytoin and carbamazepine. J. Immunol. 155:462.
4. Weltzien, H. U., C. Moulon, S. Martin, E. Padovan, U. Hartmann, and J. Kohler. 1996. T cell immune response to haptens: structural models for allergic and autoimmune reactions. Toxicology 107:141.
5. Padovan, E., T. Bauer, M. M. Tongia, H. Kalbacher, and H. U. Weltzien. 1997. Penicilloyl peptides are recognized as T cell antigenic determinants in penicillin allergy. Eur. J. Immunol. 27:1303.
6. Schnyder, B., D. Mauri-Hellweg, M. Zanni, F. Bettens, and W. J. Pichler. 1997. Direct, MHC-dependent presentation of the drug sulfamethoxazole to human αβ T cell clones. J. Clin. Invest. 100:136.
7. + T cell clones. Int. Immunol. 10:507.
8. Zanni, M. P., S. von Greyerz, B. Schnyder, K. A. Brander, K. Frutig, Y. Hari, S. Valitutti, and W. J. Pichler. 1998. HLA restricted, processing- and metabolism-independent pathway of drug recognition by human αβ T lymphocytes. J. Clin. Invest. 102:1531.
9. Kersh, G. J., and P. M. Allen. 1996. Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands. J. Exp. Med. 184:1259.
10. Evavold, B. D., and P. M. Allen. 1991. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 252:1308.
11. De Magistris, M. T., J. Alexander, M. Coggeshalll, A. Altman, F. C. A. Gaeta, H. M. Grey, and A. Sette. 1992. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68:625.
12. Sloan-Lancaster J., B. D. Evavold, and P. M. Allen. 1993. Induction of T cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363:156.
13. Sloan-Lancaster, J., and P. M. Allen. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1.
14. Valitutti, S., M. Dessing, K. Aktories, H. Gallati, and A. Lanzavecchia. 1995. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy: role of T cell actin cytoskeleton. J. Exp. Med. 181:577.
15. Valitutti, S., S. Müller, M. Cella, E. Padovan, and A. Lanzavecchia. 1995. Serial triggering of many T cell receptors by a few peptide-MHC complexes. Nature 375:148.
16. Viola, A., and A. Lanzavecchia. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science 273:104.
17. Lyons, D. S., S. A. Lieberman, J. Hampl, J.J. Boniface, Y. Chien, L. J. Berg, and M. M. Davis. 1996. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 5:53.
18. Kessler, B., D. Hudrisier, J. C. Cerottini, and I. F. Luescher. 1997. Role of CD8 in aberrant function of cytotoxic T lymphocytes. J. Exp. Med. 186:2033.
19. Valitutti, S., and A. Lanzavecchia. 1997. Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol. Today 18:299.
20. Viola, A., S. Linkert, and A. Lanzavecchia. 1997. A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands but does not affect triggering by high-affinity anti-CD3 antibodies. Eur. J. Immunol. 27:3080.
21. b-restricted TNP epitopes. J. Immunol. 151:678.
22. d-restricted cloned CTL specific for a photoreactive peptide derivative. Immunity 3:51.
23. Kohler, J., S. Martin, U. Pflugenfelder, H. Ruh, J. Vollmer, and H. U. Weltzien. 1995. Cross-reactive trinitrophenylated peptides as antigens for class II major histocompatibility complex-restricted T-cells and inducers of contact sensitivity in mice: limited T cell receptor repertoire. Eur. J. Immunol. 25:92.
24. Preckel, T., R. Grimm, S. Martin, and H. U. Weltzien. 1997. Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors. J. Exp. Med. 185:1803.
25. Zanni, M. P., D. Mauri-Hellweg, C. Brander, T. Wendland, B. Schnyder, E. Frei, S. von Greyerz, A. Bircher, and W. J. Pichler. 1997. Characterization of lidocaine-speciric T cells. J. Immunol. 158:1139.
26. Elsasser-Beile, U., S. von Kleist, and H. Gallati. 1991. Evaluation of a test for measuring cytokine production in human whole blood cell cultures. J. Immunol. Methods 139:191.
27. Park, B. K., J. W. Coleman, and N. R. Kitteringham. 1987. Drug disposition and drug hypersensitivity. Biochem. Phamacol. 36:581.
28. Van der Ven, A. J. A. M., M. A. Mantel, T. B. Vree, P. P. Koopmans, and J. V. M. van der Meer. 1994. Formation and elimination of sulphamethoxazole hydroxylamine after oral administration of sulphamethoxazole. Br. J. Clin. Pharmacol. 38:147.
29. Davis, M. M., and P. J. Bjorkman. 1988. T cell antigen receptor genes and T cell recognition. Nature 334:395.
30. Jorgensen, J. L., U. Esser, B. Fazekas de St. Groth, P. A. Reay, and M. M. Davis. 1992. Mapping T cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 355:224.
31. Mauri-Hellweg, D., M. P. Zanni, E. Frei, F. Bettens, C. Brander, and W. J. Pichler. 1996. Crossreactivity of T cell lines and clones to β-lactam antibiotics. J. Immunol. 157:1071.
32. Vollmer, J., M. Fritz, A. Doromy, H. U. Weltzien, and C. Moulon. 1997. Dominance of the BV17 element in nickel-specific human T cell receptors relates to severity of contact sensitivity. Eur. J. Immunol. 27:1865.
33. Hausmann, S., and K. W. Wucherpfennig. 1997. Activation of autoreactive T cells by peptides from human pathogens. Curr. Opin. Immunol. 9:831.
34. Chen Y. Z., S. Matsushita, and Y. Nishimura. 1996. Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation. J. Immunol. 157:3783.
35. Jameson, S. C., and M. J. Bevan. 1995. T cell receptor antagonists and partial agonists. Immunity 2:1.
36. Chan, A. C., and A. S. Shaw. 1995. Regulation of antigen receptor signal transduction by protein tyrosine kinases. Curr. Opin. Immunol. 8:394.
37. McKeithan, T. W. 1995. Kinetic proofreading in T cell receptor signal transduction. Proc. Natl. Acad. Sci. USA 92:5042.
38. Rabinowitz, J. D., C. Beeson, D. S. Lyons, M. M. Davis, and H. M. McConnell. 1996. Kinetic discrimination in T cell activation. Proc. Natl. Acad. Sci. USA 93:1401.
39. Lanzavecchia, A., P. A. Reid, and C. Watts. 1992. Irreversible association of peptides with class II MHC molecules in living cells. Nature 357:249.
40. Nelson, C. A., S. J. Petzold, and E. R. Unanue. 1994. Peptides determine the lifespan of MHC class II molecules in the antigen presenting cell. Nature 37:250.
41. λ complexes: correlation of the dissociation rate with T cell responsiveness. Proc. Natl. Acad. Sci. USA 91: 12862.